Endotoxin activates de novo sphingolipid biosynthesis via nuclear factor kappa B-mediated upregulation of Sptlc2

Prostaglandins and Other Lipid Mediators

Volumn 94, Issue 1-2, 2011, Pages 44-52

  Chang, Zhi Qiang ^a,b   Lee, Su Yeon ^a   Kim, Hye Jin ^a   Kim, Jung Ran ^a   Kim, Su Jung ^a   Hong, In Kyung ^a   Oh, Byung Chul ^a   Choi, Cheol Soo ^a   Goldberg, Ira J ^c   Park, Tae Sik ^a  

^a Gachon University College of Medicine   (South Korea)

^b YELLOW SEA FISHERIES RESEARCH INSTITUTE   (China)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Ceramide; Inflammation; Macrophage; NF B; Serine palmitoyltransferase

Indexed keywords

CERAMIDE; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; SERINE PALMITOYLTRANSFERASE; SERINE PALMITOYLTRANSFERASE SPTLC2; SPHINGOLIPID; SPHINGOMYELIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOSYNTHESIS; CHROMATIN IMMUNOPRECIPITATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; UPREGULATION;

ANIMALS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; SERINE C-PALMITOYLTRANSFERASE; SPHINGOLIPIDS; SPHINGOMYELINS; TRANSFECTION; UP-REGULATION;

EID: 79551555431     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2010.12.003     Document Type: Article

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