Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema

American Journal of Respiratory and Critical Care Medicine

Volumn 181, Issue 4, 2010, Pages 344-352

  Diab, Khalil J ^a   Adamowicz, Jeremy J ^a   Kamocki, Krzysztof ^a   Rush, Natalia I ^a   Garrison, Jana ^a   Gu, Yuan ^a   Schweitzer, Kelly S ^a   Skobeleva, Anastasia ^b   Rajashekhar, Gangaraju ^c   Hubbard, Walter C ^d   Berdyshev, Evgeny V ^b   Petrache, Irina ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c INDIANA UNIVERSITY   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Apoptosis; Ceramide; Chronic obstructive pulmonary disease; Endothelial cells; Vascular endothelial growth factor

Indexed keywords

5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; CASPASE 3; CERAMIDE; DIHYDROCERAMIDE; FINGOLIMOD; RNA; SEMAXANIB; SPHINGANINE; SPHINGOLIPID; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE KINASE; SPHINGOSINE KINASE 1; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNOBLOTTING; LIQUID CHROMATOGRAPHY; LUNG ALVEOLUS; LUNG ALVEOLUS CELL; LUNG EMPHYSEMA; LUNG PARENCHYMA; MALE; MORPHOMETRICS; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; CERAMIDES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POLYMERASE CHAIN REACTION; PROPYLENE GLYCOLS; PULMONARY ALVEOLI; PULMONARY EMPHYSEMA; PYRROLES; RECEPTORS, LYSOSPHINGOLIPID; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 76149139431     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200906-0826OC     Document Type: Article

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