Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling

Journal of Lipid Research

Volumn 50, Issue 6, 2009, Pages 1101-1108

  Hamai, Hiroko ^a   Keyserman, Fannie ^a   Quittell, Lynne M ^a   Worgall, Tilla S ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cystic fibrosis transmembrane conductance regulator; Long chain base subunit 1; Serinepalmitoyl transferase; Sphinganine; Sphingomyelin; Sphingosine

Indexed keywords

CERAMIDE; SERINE PALMITOYLTRANSFERASE; SPHINGANINE; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOSINE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID COMPOSITION; LIPOGENESIS; LUNG ALVEOLUS EPITHELIUM; MEMBRANE STRUCTURE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WILD TYPE;

CELL LINE; CELL MEMBRANE; CERAMIDES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; LIPID METABOLISM; MUTATION; RECOMBINANT PROTEINS; SERINE C-PALMITOYLTRANSFERASE; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; TRANSDUCTION, GENETIC;

EID: 67049121806     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800427-JLR200     Document Type: Article

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