메뉴 건너뛰기




Volumn 468, Issue 3, 2016, Pages 475-490

Modulating Ca2+ signals: a common theme for TMEM16, Ist2, and TMC

Author keywords

Anoctamin 1; Anoctamin 6; Ca2+ signaling; ER Ca2+ store; Ist2; Lipid rafts; nhTMEM16; SCP2; Secretion; TMC; TMEM16 proteins; TMEM16A; TMEM16F

Indexed keywords

ANOCTAMIN; ANOCTAMIN 1; ANOCTAMIN 10; ANOCTAMIN 2; ANOCTAMIN 3; ANOCTAMIN 5; ANOCTAMIN 6; CALCIUM ACTIVATED CHLORIDE CHANNEL; CALCIUM ION; CHLORIDE ION; UNCLASSIFIED DRUG; ANO1 PROTEIN, HUMAN; CALCIUM; CHLORIDE; CHLORIDE CHANNEL; TUMOR PROTEIN;

EID: 84957966707     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-015-1767-4     Document Type: Review
Times cited : (58)

References (202)
  • 2
    • 84928253329 scopus 로고    scopus 로고
    • Conditional knockout of TMEM16A/anoctamin1 abolishes the calcium-activated chloride current in mouse vomeronasal sensory neurons
    • PID: 2577987
    • Amjad A, Hernandez-Clavijo A, Pifferi S, Maurya DK, Boccaccio A, Franzot J, Rock JR, Menini A (2015) Conditional knockout of TMEM16A/anoctamin1 abolishes the calcium-activated chloride current in mouse vomeronasal sensory neurons. J Gen Physiol 145:285–301
    • (2015) J Gen. Physiol. , vol.145 , pp. 285-301
    • Amjad, A.1    Hernandez-Clavijo, A.2    Pifferi, S.3    Maurya, D.K.4    Boccaccio, A.5    Franzot, J.6    Rock, J.R.7    Menini, A.8
  • 5
    • 77949884841 scopus 로고    scopus 로고
    • ER localized bestrophin1 acts as a counter-ion channel to activate Ca2+ dependent ion channels TMEM16A and SK4
    • PID: 1982386
    • Barro Soria R, AlDehni F, Almaca J, Witzgall R, Schreiber R, Kunzelmann K (2009) ER localized bestrophin1 acts as a counter-ion channel to activate Ca2+ dependent ion channels TMEM16A and SK4. Pflügers Arch 459:485–497
    • (2009) Pflügers Arch , vol.459 , pp. 485-497
    • Barro Soria, R.1    AlDehni, F.2    Almaca, J.3    Witzgall, R.4    Schreiber, R.5    Kunzelmann, K.6
  • 8
    • 84964698402 scopus 로고    scopus 로고
    • Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility
    • PID: 2492805
    • Bernstein K, Vink JY, Fu XW, Wakita H, Danielsson J, Wapner R, Gallos G (2014) Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility. Am J Obstet Gynecol 211(688):e1–10
    • (2014) Am J Obstet. Gynecol , vol.211 , Issue.688 , pp. e1-e10
    • Bernstein, K.1    Vink, J.Y.2    Fu, X.W.3    Wakita, H.4    Danielsson, J.5    Wapner, R.6    Gallos, G.7
  • 9
    • 84929514908 scopus 로고    scopus 로고
    • Anoctamin-1 in the juvenile rat urinary bladder
    • PID: 2518153
    • Bijos DA, Drake MJ, Vahabi B (2014) Anoctamin-1 in the juvenile rat urinary bladder. PLoS ONE 9:e106190
    • (2014) PLoS ONE , vol.9 , pp. e106190
    • Bijos, D.A.1    Drake, M.J.2    Vahabi, B.3
  • 14
    • 84918807150 scopus 로고    scopus 로고
    • X-ray structure of a calcium-activated TMEM16 lipid scramblase
    • PID: 2538353
    • Brunner JD, Lim NK, Schenck S, Duerst A, Dutzler R (2014) X-ray structure of a calcium-activated TMEM16 lipid scramblase. Nature 516:207–212
    • (2014) Nature , vol.516 , pp. 207-212
    • Brunner, J.D.1    Lim, N.K.2    Schenck, S.3    Duerst, A.4    Dutzler, R.5
  • 15
    • 84899750733 scopus 로고    scopus 로고
    • Anoctamin 1 induces calcium-activated chloride secretion and tissue proliferation in polycystic kidney disease
    • PID: 2415296
    • Buchholz B, Faria D, Schley G, Schreiber R, Eckardt KU, Kunzelmann K (2014) Anoctamin 1 induces calcium-activated chloride secretion and tissue proliferation in polycystic kidney disease. Kidney Int 85:1058–1067
    • (2014) Kidney Int , vol.85 , pp. 1058-1067
    • Buchholz, B.1    Faria, D.2    Schley, G.3    Schreiber, R.4    Eckardt, K.U.5    Kunzelmann, K.6
  • 17
    • 84866992308 scopus 로고    scopus 로고
    • Bulley S, Neeb ZP, Burris SK, Bannister JP, Thomas-Gatewood CM, Jangsangthong W, and Jaggar JH (2012) TMEM16A channels contribute to the myogenic response in cerebral arteries. Circ. Res. (in press) 111: 1027-1036
    • Bulley S, Neeb ZP, Burris SK, Bannister JP, Thomas-Gatewood CM, Jangsangthong W, and Jaggar JH (2012) TMEM16A channels contribute to the myogenic response in cerebral arteries. Circ. Res. (in press) 111: 1027-1036.
  • 19
    • 84937975018 scopus 로고    scopus 로고
    • Haploinsufficiency of ANO6, NELL2 and DBX2 in a boy with intellectual disability and growth delay
    • PID: 2584605
    • Carlsen EO, Frengen E, Fannemel M, Misceo D (2015) Haploinsufficiency of ANO6, NELL2 and DBX2 in a boy with intellectual disability and growth delay. Am J Med Genet A 167A(8):1890–6. doi:10.1002/ajmg.a.37079
    • (2015) Am J Med. Genet. A , vol.167A , Issue.8 , pp. 1890-1896
    • Carlsen, E.O.1    Frengen, E.2    Fannemel, M.3    Misceo, D.4
  • 20
    • 79955974150 scopus 로고    scopus 로고
    • Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome
    • PID: 2151196
    • Castoldi E, Collins PW, Williamson PL, Bevers EM (2011) Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome. Blood 117:4399–4400
    • (2011) Blood , vol.117 , pp. 4399-4400
    • Castoldi, E.1    Collins, P.W.2    Williamson, P.L.3    Bevers, E.M.4
  • 22
    • 84910141888 scopus 로고    scopus 로고
    • Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts
    • PID: 2512799
    • Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O (2014) Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts. Dev Biol 394:54–64
    • (2014) Dev. Biol. , vol.394 , pp. 54-64
    • Cerqueira, D.M.1    Tran, U.2    Romaker, D.3    Abreu, J.G.4    Wessely, O.5
  • 26
    • 84901032996 scopus 로고    scopus 로고
    • Prognostic significance of TMEM16A, PPFIA1, and FADD expression in invasive ductal carcinoma of the breast
    • PID: 2488628
    • Choi EJ, Yun JA, Jabeen S, Jeon EK, Won HS, Ko YH, Kim SY (2014) Prognostic significance of TMEM16A, PPFIA1, and FADD expression in invasive ductal carcinoma of the breast. World J Surg Oncol 12:137–12
    • (2014) World J Surg. Oncol. , vol.12 , pp. 112-137
    • Choi, E.J.1    Yun, J.A.2    Jabeen, S.3    Jeon, E.K.4    Won, H.S.5    Ko, Y.H.6    Kim, S.Y.7
  • 27
    • 84904726032 scopus 로고    scopus 로고
    • TMEM16A knockdown abrogates two different Ca-activated Cl currents and contractility of smooth muscle in rat mesenteric small arteries
    • PID: 2416223
    • Dam VS, Boedtkjer DM, Nyvad J, Aalkjaer C, Matchkov V (2013) TMEM16A knockdown abrogates two different Ca-activated Cl currents and contractility of smooth muscle in rat mesenteric small arteries. Pflugers Arch 466:1391–1409
    • (2013) Pflugers Arch. , vol.466 , pp. 1391-1409
    • Dam, V.S.1    Boedtkjer, D.M.2    Nyvad, J.3    Aalkjaer, C.4    Matchkov, V.5
  • 28
    • 84979854379 scopus 로고    scopus 로고
    • Danielsson J, Perez-Zoghbi J, Bernstein K, Barajas MB, Zhang Y, Kumar S, Sharma PK, Gallos G, and Emala CW (2015) Antagonists of the TMEM16A calcium-activated chloride channel modulate airway smooth muscle tone and intracellular calcium. Anesthesiology (in press
    • Danielsson J, Perez-Zoghbi J, Bernstein K, Barajas MB, Zhang Y, Kumar S, Sharma PK, Gallos G, and Emala CW (2015) Antagonists of the TMEM16A calcium-activated chloride channel modulate airway smooth muscle tone and intracellular calcium. Anesthesiology (in press)
  • 29
    • 84859431577 scopus 로고    scopus 로고
    • Expression patterns of anoctamin 1 and anoctamin 2 chloride channels in the mammalian nose
    • PID: 2231484
    • Dauner K, Lissmann J, Jeridi S, Frings S, Mohrlen F (2012) Expression patterns of anoctamin 1 and anoctamin 2 chloride channels in the mammalian nose. Cell Tissue Res 347:327–341
    • (2012) Cell Tissue Res. , vol.347 , pp. 327-341
    • Dauner, K.1    Lissmann, J.2    Jeridi, S.3    Frings, S.4    Mohrlen, F.5
  • 31
    • 84890352250 scopus 로고    scopus 로고
    • Direct recording and molecular identification of the calcium channel of primary cilia
    • PID: 2433628
    • DeCaen PG, Delling M, Vien TN, Clapham DE (2013) Direct recording and molecular identification of the calcium channel of primary cilia. Nature 504:315–318
    • (2013) Nature , vol.504 , pp. 315-318
    • DeCaen, P.G.1    Delling, M.2    Vien, T.N.3    Clapham, D.E.4
  • 32
    • 84856401688 scopus 로고    scopus 로고
    • [Muscular dystrophy due to mutations in anoctamin 5: clinical and molecular genetic findings.] Muskeldystrophie infolge Anoctamin-5-Mutationen: Klinische und molekulargenetische Befunde. DEP - 20110709
    • PID: 2173927
    • Deschauer M, Joshi PR, Glaser D, Hanisch F, Stoltenburg G, Zierz S (2011) [Muscular dystrophy due to mutations in anoctamin 5: clinical and molecular genetic findings.] Muskeldystrophie infolge Anoctamin-5-Mutationen: Klinische und molekulargenetische Befunde. DEP - 20110709. Nervenarzt 82:1596–1603
    • (2011) Nervenarzt. , vol.82 , pp. 1596-1603
    • Deschauer, M.1    Joshi, P.R.2    Glaser, D.3    Hanisch, F.4    Stoltenburg, G.5    Zierz, S.6
  • 36
    • 65749107143 scopus 로고    scopus 로고
    • Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart
    • PID: 1917165
    • Duan D (2009) Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart. J Physiol 587:2163–2177
    • (2009) J Physiol. , vol.587 , pp. 2163-2177
    • Duan, D.1
  • 38
    • 84871865470 scopus 로고    scopus 로고
    • Mechanosensitive Cl- secretion in biliary epithelium mediated through TMEM16A. Am. J Physiol Gastrointest
    • Dutta AK, Woo K, Khimji AK, Kresge C, Feranchak AP (2012) Mechanosensitive Cl- secretion in biliary epithelium mediated through TMEM16A. Am. J Physiol Gastrointest. Liver Physiol 304:G87–G98
    • (2012) Liver Physiol , vol.304 , pp. G87-G98
    • Dutta, A.K.1    Woo, K.2    Khimji, A.K.3    Kresge, C.4    Feranchak, A.P.5
  • 41
    • 70649107057 scopus 로고    scopus 로고
    • A conserved, lipid-mediated sorting mechanism of yeast Ist2 and mammalian STIM proteins to the peripheral ER
    • PID: 1984591
    • Ercan E, Momburg F, Engel U, Temmerman K, Nickel W, Seedorf M (2009) A conserved, lipid-mediated sorting mechanism of yeast Ist2 and mammalian STIM proteins to the peripheral ER. Traffic 10:1802–1818
    • (2009) Traffic , vol.10 , pp. 1802-1818
    • Ercan, E.1    Momburg, F.2    Engel, U.3    Temmerman, K.4    Nickel, W.5    Seedorf, M.6
  • 46
  • 47
    • 77951236838 scopus 로고    scopus 로고
    • Intricate interaction between store-operated calcium entry and calcium-activated chloride channels in pulmonary artery smooth muscle cells
    • PID: 2020472
    • Forrest AS, Angermann JE, Raghunathan R, Lachendro C, Greenwood IA, Leblanc N (2010) Intricate interaction between store-operated calcium entry and calcium-activated chloride channels in pulmonary artery smooth muscle cells. Adv Exp Med Biol 661:31–55
    • (2010) Adv. Exp. Med. Biol. , vol.661 , pp. 31-55
    • Forrest, A.S.1    Angermann, J.E.2    Raghunathan, R.3    Lachendro, C.4    Greenwood, I.A.5    Leblanc, N.6
  • 54
    • 67649518731 scopus 로고    scopus 로고
    • Anoctamin and transmembrane channel-like proteins are evolutionarily related
    • PID: 1951353
    • Hahn Y, Kim DS, Pastan IH, Lee B (2009) Anoctamin and transmembrane channel-like proteins are evolutionarily related. Int J Mol Med 24:51–55
    • (2009) Int. J. Mol. Med. , vol.24 , pp. 51-55
    • Hahn, Y.1    Kim, D.S.2    Pastan, I.H.3    Lee, B.4
  • 57
    • 84891778834 scopus 로고    scopus 로고
    • Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity
    • PID: 2435780
    • Harper MT, Poole AW (2013) Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity. Cell Death Dis 4:e969
    • (2013) Cell Death. Dis. , vol.4 , pp. e969
    • Harper, M.T.1    Poole, A.W.2
  • 62
    • 84883313607 scopus 로고    scopus 로고
    • TMEM16C facilitates Na(+)-activated K(+) currents in rat sensory neurons and regulates pain processing
    • PID: 2387259
    • Huang F, Wang X, Ostertag EM, Nuwal T, Huang B, Jan YN, Basbaum AI, Jan LY (2013) TMEM16C facilitates Na(+)-activated K(+) currents in rat sensory neurons and regulates pain processing. Nat Neurosci 16:1284–1290
    • (2013) Nat. Neurosci. , vol.16 , pp. 1284-1290
    • Huang, F.1    Wang, X.2    Ostertag, E.M.3    Nuwal, T.4    Huang, B.5    Jan, Y.N.6    Basbaum, A.I.7    Jan, L.Y.8
  • 64
    • 84859645387 scopus 로고    scopus 로고
    • Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons
    • PID: 2250063
    • Huang WC, Xiao S, Huang F, Harfe BD, Jan YN, Jan LY (2012) Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron 74:179–192
    • (2012) Neuron. , vol.74 , pp. 179-192
    • Huang, W.C.1    Xiao, S.2    Huang, F.3    Harfe, B.D.4    Jan, Y.N.5    Jan, L.Y.6
  • 69
    • 84879468128 scopus 로고    scopus 로고
    • Presynaptic localization and possible function of calcium-activated chloride channel anoctamin 1 in the mammalian retina
    • PID: 2384080
    • Jeon JH, Paik SS, Chun MH, Oh U, Kim IB (2013) Presynaptic localization and possible function of calcium-activated chloride channel anoctamin 1 in the mammalian retina. PLoS ONE 8:e67989
    • (2013) PLoS ONE , vol.8 , pp. e67989
    • Jeon, J.H.1    Paik, S.S.2    Chun, M.H.3    Oh, U.4    Kim, I.B.5
  • 70
    • 80052784394 scopus 로고    scopus 로고
    • Expression and immunohistochemical localization of TMEM16A/anoctamin 1, a calcium-activated chloride channel in the mouse cochlea
    • PID: 2177978
    • Jeon JH, Park JW, Lee JW, Jeong SW, Yeo SW, Kim IB (2011) Expression and immunohistochemical localization of TMEM16A/anoctamin 1, a calcium-activated chloride channel in the mouse cochlea. Cell Tissue Res 345:223–230
    • (2011) Cell Tissue Res. , vol.345 , pp. 223-230
    • Jeon, J.H.1    Park, J.W.2    Lee, J.W.3    Jeong, S.W.4    Yeo, S.W.5    Kim, I.B.6
  • 71
    • 84957981404 scopus 로고    scopus 로고
    • Jin X, Shah S, Du X, Zhang H, and Gamper N (2014) Activation of Ca2+-activated Cl- channel ANO1 by localized Ca2+ signals. J Physiol.(in press)
    • Jin X, Shah S, Du X, Zhang H, and Gamper N (2014) Activation of Ca2+-activated Cl- channel ANO1 by localized Ca2+ signals. J Physiol.(in press).
  • 73
    • 84891920748 scopus 로고    scopus 로고
    • Anoctamin 5 muscular dystrophy associated with a silent p.Leu115Leu mutation resulting in exon skipping
    • PID: 2423905
    • Joshi PR, Glaser D, Dressel C, Kress W, Weis J, Deschauer M (2013) Anoctamin 5 muscular dystrophy associated with a silent p.Leu115Leu mutation resulting in exon skipping. Neuromuscul Disord 24:43–47
    • (2013) Neuromuscul. Disord. , vol.24 , pp. 43-47
    • Joshi, P.R.1    Glaser, D.2    Dressel, C.3    Kress, W.4    Weis, J.5    Deschauer, M.6
  • 75
    • 84891763415 scopus 로고    scopus 로고
    • Anoctamin 6 differs from VRAC and VSOAC but is involved in apoptosis and supports volume regulation in the presence of Ca
    • PID: 2441953
    • Juul CA, Grubb S, Poulsen KA, Kyed T, Hashem N, Lambert IH, Larsen EH, Hoffmann EK (2014) Anoctamin 6 differs from VRAC and VSOAC but is involved in apoptosis and supports volume regulation in the presence of Ca. Pflugers Arch 466:1899–1910
    • (2014) Pflugers Arch , vol.466 , pp. 1899-1910
    • Juul, C.A.1    Grubb, S.2    Poulsen, K.A.3    Kyed, T.4    Hashem, N.5    Lambert, I.H.6    Larsen, E.H.7    Hoffmann, E.K.8
  • 76
    • 84901002681 scopus 로고    scopus 로고
    • Expression of transient receptor potential vanilloid 1 and anoctamin 1 in rat trigeminal ganglion neurons innervating the tongue
    • PID: 2479278
    • Kanazawa T, Matsumoto S (2014) Expression of transient receptor potential vanilloid 1 and anoctamin 1 in rat trigeminal ganglion neurons innervating the tongue. Brain Res Bull 106:17–20
    • (2014) Brain Res. Bull. , vol.106 , pp. 17-20
    • Kanazawa, T.1    Matsumoto, S.2
  • 78
  • 82
    • 84922481177 scopus 로고    scopus 로고
    • Novel ANO5 homozygous microdeletion causing myalgia and unprovoked rhabdomyolysis in an Arabic man
    • PID: 2488986
    • Lahoria R, Winder TL, Lui J, Al Owain MA, Milone M (2014) Novel ANO5 homozygous microdeletion causing myalgia and unprovoked rhabdomyolysis in an Arabic man. Muscle Nerve 50:610–613
    • (2014) Muscle Nerve. , vol.50 , pp. 610-613
    • Lahoria, R.1    Winder, T.L.2    Lui, J.3    Al Owain, M.A.4    Milone, M.5
  • 83
    • 84892763451 scopus 로고    scopus 로고
    • Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity. Mol. Pain
    • Lee B, Cho H, Jung J, Yang YD, Yang DJ, and Oh U (2014) Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity. Mol. Pain. 10.1186/1744-8069-10-5.
    • (2014) 10.1186/1744-8069-10-5
    • Lee, B.1    Cho, H.2    Jung, J.3    Yang, Y.D.4    Yang, D.J.5    Oh, U.6
  • 84
    • 74949102212 scopus 로고    scopus 로고
    • Mechanisms of Ca2+-stimulated fluid secretion by porcine bronchial submucosal gland serous acinar cells
    • PID: 1996598
    • Lee RJ, Foskett JK (2009) Mechanisms of Ca2+-stimulated fluid secretion by porcine bronchial submucosal gland serous acinar cells. Am J Physiol Lung Cell Mol Physiol 298:L210–L231
    • (2009) Am. J. Physiol Lung Cell Mol. Physiol. , vol.298 , pp. L210-L231
    • Lee, R.J.1    Foskett, J.K.2
  • 85
    • 84902333338 scopus 로고    scopus 로고
    • Ca signaling and fluid secretion by secretory cells of the airway epithelium
    • PID: 2470309
    • Lee RJ, Foskett JK (2014) Ca signaling and fluid secretion by secretory cells of the airway epithelium. Cell Calcium 55:325–336
    • (2014) Cell Calcium. , vol.55 , pp. 325-336
    • Lee, R.J.1    Foskett, J.K.2
  • 86
    • 80053429773 scopus 로고    scopus 로고
    • Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome
    • PID: 2195838
    • Lhermusier T, Chap H, Payrastre B (2011) Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome. J Thromb Haemost 9:1883–1891
    • (2011) J Thromb. Haemost. , vol.9 , pp. 1883-1891
    • Lhermusier, T.1    Chap, H.2    Payrastre, B.3
  • 87
    • 79961104749 scopus 로고    scopus 로고
    • Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca(2+) sparks in airway myocytes
    • PID: 2174684
    • Lifshitz LM, Carmichael JD, Lai FA, Sorrentino V, Bellve K, Fogarty KE, ZhuGe R (2011) Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca(2+) sparks in airway myocytes. J Gen Physiol 138:195–209
    • (2011) J Gen. Physiol. , vol.138 , pp. 195-209
    • Lifshitz, L.M.1    Carmichael, J.D.2    Lai, F.A.3    Sorrentino, V.4    Bellve, K.5    Fogarty, K.E.6    ZhuGe, R.7
  • 88
    • 84929510604 scopus 로고    scopus 로고
    • TMEM16A mediates the hypersecretion of mucus induced by interleukin-13
    • PID: 2577001
    • Lin J, Jiang Y, Li L, Liu Y, Tang H, Jiang D (2015) TMEM16A mediates the hypersecretion of mucus induced by interleukin-13. Exp Cell Res 334:260–269
    • (2015) Exp. Cell Res. , vol.334 , pp. 260-269
    • Lin, J.1    Jiang, Y.2    Li, L.3    Liu, Y.4    Tang, H.5    Jiang, D.6
  • 91
    • 84929650178 scopus 로고    scopus 로고
    • TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGF-beta signaling
    • PID: 2583916
    • Liu F, Cao QH, Lu J, Luo B, Lu XF, Luo RC, Wang XG (2015) TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGF-beta signaling. Oncotarget 6:11585–11599
    • (2015) Oncotarget , vol.6 , pp. 11585-11599
    • Liu, F.1    Cao, Q.H.2    Lu, J.3    Luo, B.4    Lu, X.F.5    Luo, R.C.6    Wang, X.G.7
  • 92
    • 84866143707 scopus 로고    scopus 로고
    • Inhibition of Ca(2+)-activated Cl(-) channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma
    • PID: 2282016
    • Liu W, Lu M, Liu B, Huang Y, Wang K (2012) Inhibition of Ca(2+)-activated Cl(-) channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma. Cancer Lett 326:41–51
    • (2012) Cancer Lett. , vol.326 , pp. 41-51
    • Liu, W.1    Lu, M.2    Liu, B.3    Huang, Y.4    Wang, K.5
  • 94
    • 84866305183 scopus 로고    scopus 로고
    • Selective pattern of muscle involvement seen in distal muscular dystrophy associated with anoctamin 5 mutations: a follow-up muscle MRI study
    • PID: 2298076
    • Mahjneh I, Bashir R, Kiuru-Enari S, Linssen W, Lamminen A, Visser M (2012) Selective pattern of muscle involvement seen in distal muscular dystrophy associated with anoctamin 5 mutations: a follow-up muscle MRI study. Neuromuscul Disord 22(Suppl 2):S130–S136
    • (2012) Neuromuscul. Disord. , vol.22 , pp. S130-S136
    • Mahjneh, I.1    Bashir, R.2    Kiuru-Enari, S.3    Linssen, W.4    Lamminen, A.5    Visser, M.6
  • 97
    • 84870793680 scopus 로고    scopus 로고
    • ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology
    • PID: 2323795
    • Manford AG, Stefan CJ, Yuan HL, Macgurn JA, Emr SD (2012) ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology. Dev Cell 23:1129–1140
    • (2012) Dev. Cell. , vol.23 , pp. 1129-1140
    • Manford, A.G.1    Stefan, C.J.2    Yuan, H.L.3    Macgurn, J.A.4    Emr, S.D.5
  • 98
    • 77954517197 scopus 로고    scopus 로고
    • TMEM16A/Anoctamin1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells
    • PID: 2042128
    • Manoury B, Tamuleviciute A, Tammaro P (2010) TMEM16A/Anoctamin1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells. J Physiol 588:2305–2314
    • (2010) J Physiol. , vol.588 , pp. 2305-2314
    • Manoury, B.1    Tamuleviciute, A.2    Tammaro, P.3
  • 103
  • 105
    • 80355129636 scopus 로고    scopus 로고
    • Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction
    • PID: 2183602
    • Namkung W, Yao Z, Finkbeiner WE, Verkman AS (2011) Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. FASEB J 25:4048–4062
    • (2011) FASEB J. , vol.25 , pp. 4048-4062
    • Namkung, W.1    Yao, Z.2    Finkbeiner, W.E.3    Verkman, A.S.4
  • 106
    • 84861715725 scopus 로고    scopus 로고
    • Human spermatozoa possess a calcium-dependent chloride channel that may participate in the acrosomal reaction
    • PID: 2247377
    • Orta G, Ferreira G, Jose O, Trevino CL, Beltran C, Darszon A (2012) Human spermatozoa possess a calcium-dependent chloride channel that may participate in the acrosomal reaction. J Physiol 590:2659–2675
    • (2012) J. Physiol. , vol.590 , pp. 2659-2675
    • Orta, G.1    Ferreira, G.2    Jose, O.3    Trevino, C.L.4    Beltran, C.5    Darszon, A.6
  • 110
    • 79955642356 scopus 로고    scopus 로고
    • Rotavirus toxin NSP4 activates the calcium dependent chloride channel TMEM16A and inhibits absorptive Na+ transport
    • PID: 2139989
    • Ousingsawat J, Tian Y, AlDehni F, Roussa E, Schreiber R, Mirza M, Cook DI, Kunzelmann K (2011) Rotavirus toxin NSP4 activates the calcium dependent chloride channel TMEM16A and inhibits absorptive Na+ transport. Pflügers Arch 461:579–589
    • (2011) Pflügers Arch , vol.461 , pp. 579-589
    • Ousingsawat, J.1    Tian, Y.2    AlDehni, F.3    Roussa, E.4    Schreiber, R.5    Mirza, M.6    Cook, D.I.7    Kunzelmann, K.8
  • 113
    • 84900406113 scopus 로고    scopus 로고
    • Structure and function of TMEM16 proteins (anoctamins)
    • PID: 2469235
    • Pedemonte N, Galietta LJ (2014) Structure and function of TMEM16 proteins (anoctamins). Physiol Rev 94:419–459
    • (2014) Physiol Rev. , vol.94 , pp. 419-459
    • Pedemonte, N.1    Galietta, L.J.2
  • 114
    • 84862980716 scopus 로고    scopus 로고
    • Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network
    • PID: 2268520
    • Perez-Cornejo P, Gokhale A, Duran C, Cui Y, Xiao Q, Hartzell HC, Faundez V (2012) Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network. Proc Natl Acad Sci U S A 109:10376–10381
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 10376-10381
    • Perez-Cornejo, P.1    Gokhale, A.2    Duran, C.3    Cui, Y.4    Xiao, Q.5    Hartzell, H.C.6    Faundez, V.7
  • 115
    • 84940892690 scopus 로고    scopus 로고
    • Phua SC, Lin YC, and Inoue T (2015) An intelligent nano-antenna: primary cilium harnesses TRP channels to decode polymodal stimuli. Cell Calcium (in press)
    • Phua SC, Lin YC, and Inoue T (2015) An intelligent nano-antenna: primary cilium harnesses TRP channels to decode polymodal stimuli. Cell Calcium (in press).
  • 116
    • 70349573000 scopus 로고    scopus 로고
    • TMEM16B induces chloride currents activated by calcium in mammalian cells
    • PID: 1947541
    • Pifferi S, Dibattista M, Menini A (2009) TMEM16B induces chloride currents activated by calcium in mammalian cells. Pflugers Arch 458:1023–1038
    • (2009) Pflugers Arch. , vol.458 , pp. 1023-1038
    • Pifferi, S.1    Dibattista, M.2    Menini, A.3
  • 117
    • 84906827685 scopus 로고    scopus 로고
    • Inhibitory role of phosphatidylinositol 4,5 bisphosphate on TMEM16A encoded calcium-activated chloride channels in rat pulmonary artery
    • PID: 2483496
    • Pritchard HA, Leblanc N, Albert AP, Greenwood IA (2014) Inhibitory role of phosphatidylinositol 4,5 bisphosphate on TMEM16A encoded calcium-activated chloride channels in rat pulmonary artery. Br J Pharmacol 171(18):4311–21. doi:10.1111/bph.12778
    • (2014) Br. J Pharmacol , vol.171 , Issue.18 , pp. 4311-4321
    • Pritchard, H.A.1    Leblanc, N.2    Albert, A.P.3    Greenwood, I.A.4
  • 120
    • 84862615722 scopus 로고    scopus 로고
    • Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation
    • PID: 2217009
    • Rievaj J, Davidson C, Nadeem A, Hollenberg M, Duszyk M, Vliagoftis H (2012) Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation. Pflugers Arch 463:497–509
    • (2012) Pflugers Arch. , vol.463 , pp. 497-509
    • Rievaj, J.1    Davidson, C.2    Nadeem, A.3    Hollenberg, M.4    Duszyk, M.5    Vliagoftis, H.6
  • 121
    • 51549098165 scopus 로고    scopus 로고
    • Expression of TMEM16 paralogs during murine embryogenesis
    • PID: 1872923
    • Rock JR, Harfe BD (2008) Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn 237:2566–2574
    • (2008) Dev. Dyn. , vol.237 , pp. 2566-2574
    • Rock, J.R.1    Harfe, B.D.2
  • 122
    • 36048993202 scopus 로고    scopus 로고
    • Identification of genes expressed in the mouse limb using a novel ZPA microarray approach
    • PID: 1791104
    • Rock JR, Lopez MC, Baker HV, Harfe BD (2007) Identification of genes expressed in the mouse limb using a novel ZPA microarray approach. Gene Expr Patterns 8:19–26
    • (2007) Gene Expr. Patterns. , vol.8 , pp. 19-26
    • Rock, J.R.1    Lopez, M.C.2    Baker, H.V.3    Harfe, B.D.4
  • 127
    • 0033570085 scopus 로고    scopus 로고
    • Calcium release at fertilization of Xenopus eggs requires type I IP(3) receptors, but not SH2 domain-mediated activation of PLCgamma or G(q)-mediated activation of PLCbeta
    • PID: 1052534
    • Runft LL, Watras J, Jaffe LA (1999) Calcium release at fertilization of Xenopus eggs requires type I IP(3) receptors, but not SH2 domain-mediated activation of PLCgamma or G(q)-mediated activation of PLCbeta. Dev Biol 214:399–411
    • (1999) Dev. Biol. , vol.214 , pp. 399-411
    • Runft, L.L.1    Watras, J.2    Jaffe, L.A.3
  • 128
    • 84901660625 scopus 로고    scopus 로고
    • The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis
    • PID: 2469459
    • Ruppersburg CC, Hartzell HC (2014) The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis. Mol Biol Cell 25:1793–1807
    • (2014) Mol. Biol. Cell. , vol.25 , pp. 1793-1807
    • Ruppersburg, C.C.1    Hartzell, H.C.2
  • 129
    • 84969386537 scopus 로고    scopus 로고
    • Presence of the Ca2+-activated chloride channel anoctamin 1 in urethra and its role in excitatory neurotransmission
    • Sancho M, Garcia-Pascual A, Triguero D (2011) Presence of the Ca2+-activated chloride channel anoctamin 1 in urethra and its role in excitatory neurotransmission. Am J Physiol Renal Physiol 91:685–693
    • (2011) Am J Physiol Renal Physiol , vol.91 , pp. 685-693
    • Sancho, M.1    Garcia-Pascual, A.2    Triguero, D.3
  • 131
    • 84939891077 scopus 로고    scopus 로고
    • Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine
    • PID: 2497490
    • Schreiber R, Faria D, Skryabin BV, Rock JR, Kunzelmann K (2014) Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine. Pflügers Arch 467:1203–1213
    • (2014) Pflügers Arch , vol.467 , pp. 1203-1213
    • Schreiber, R.1    Faria, D.2    Skryabin, B.V.3    Rock, J.R.4    Kunzelmann, K.5
  • 133
    • 51549120559 scopus 로고    scopus 로고
    • Expression cloning of TMEM16A as a calcium-activated chloride channel subunit
    • PID: 1880509
    • Schroeder BC, Cheng T, Jan YN, Jan LY (2008) Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell 134:1019–1029
    • (2008) Cell. , vol.134 , pp. 1019-1029
    • Schroeder, B.C.1    Cheng, T.2    Jan, Y.N.3    Jan, L.Y.4
  • 135
    • 84940612857 scopus 로고    scopus 로고
    • Scudieri P, Caci E, Venturini A, Sondo E, Pianigiani G, Marchetti C, Ravazzolo R, Pagani F, and Galietta LJ (2015) Ion channel and lipid scramblase activity associated with expression of tmem16F/ANO6 isoforms. J Physiol.(in press)
    • Scudieri P, Caci E, Venturini A, Sondo E, Pianigiani G, Marchetti C, Ravazzolo R, Pagani F, and Galietta LJ (2015) Ion channel and lipid scramblase activity associated with expression of tmem16F/ANO6 isoforms. J Physiol.(in press).
  • 136
    • 84878390836 scopus 로고    scopus 로고
    • TMEM16A-TMEM16B chimeras to investigate the structure-function relationship of calcium-activated chloride channels
    • PID: 2357055
    • Scudieri P, Sondo E, Caci E, Ravazzolo R, Galietta LJ (2013) TMEM16A-TMEM16B chimeras to investigate the structure-function relationship of calcium-activated chloride channels. Biochem J 452:443–455
    • (2013) Biochem. J. , vol.452 , pp. 443-455
    • Scudieri, P.1    Sondo, E.2    Caci, E.3    Ravazzolo, R.4    Galietta, L.J.5
  • 137
    • 82755163551 scopus 로고    scopus 로고
    • Constitutive exposure of phosphatidylserine on viable cells
    • PID: 2208412
    • Segawa K, Suzuki J, Nagata S (2011) Constitutive exposure of phosphatidylserine on viable cells. Proc Natl Acad Sci U S A 108:19246–19251
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 19246-19251
    • Segawa, K.1    Suzuki, J.2    Nagata, S.3
  • 138
    • 78651384517 scopus 로고    scopus 로고
    • Characterization of the oligomeric structure of the Ca2+-activated Cl- channel Ano1/TMEM16A
    • PID: 2105698
    • Sheridan JT, Worthington EN, Yu K, Gabriel SE, Hartzell HC, Tarran R (2011) Characterization of the oligomeric structure of the Ca2+-activated Cl- channel Ano1/TMEM16A. J Biol Chem 286:1381–1388
    • (2011) J Biol. Chem. , vol.286 , pp. 1381-1388
    • Sheridan, J.T.1    Worthington, E.N.2    Yu, K.3    Gabriel, S.E.4    Hartzell, H.C.5    Tarran, R.6
  • 139
    • 84878648060 scopus 로고    scopus 로고
    • TMEM16F is a component of a Ca2+-activated Cl- channel but not a volume-sensitive outwardly rectifying Cl- channel
    • PID: 2342696
    • Shimizu T, Iehara T, Sato K, Fujii T, Sakai H, Okada Y (2013) TMEM16F is a component of a Ca2+-activated Cl- channel but not a volume-sensitive outwardly rectifying Cl- channel. Am J Physiol Cell Physiol 304:C748–C759
    • (2013) Am. J Physiol Cell Physiol. , vol.304 , pp. C748-C759
    • Shimizu, T.1    Iehara, T.2    Sato, K.3    Fujii, T.4    Sakai, H.5    Okada, Y.6
  • 142
  • 144
    • 84907638078 scopus 로고    scopus 로고
    • TMC8 (EVER2) attenuates intracellular signaling by Zn2+ and Ca2+ and suppresses activation of Cl- currents
    • PID: 2522038
    • Sirianant L, Ousingsawat J, Tian Y, Schreiber R, Kunzelmann K (2014) TMC8 (EVER2) attenuates intracellular signaling by Zn2+ and Ca2+ and suppresses activation of Cl- currents. Cell Signal 26:2826–2833
    • (2014) Cell Signal. , vol.26 , pp. 2826-2833
    • Sirianant, L.1    Ousingsawat, J.2    Tian, Y.3    Schreiber, R.4    Kunzelmann, K.5
  • 145
    • 77952029786 scopus 로고    scopus 로고
    • E. coli alpha-hemolysin triggers shrinkage of erythrocytes via KCa3.1 and TMEM16A channels with subsequent phosphatidyl serine exposure
    • PID: 2023127
    • Skals M, Jensen UB, Ousingsawat J, Kunzelmann K, Leipziger J, Praetorius HA (2010) E. coli alpha-hemolysin triggers shrinkage of erythrocytes via KCa3.1 and TMEM16A channels with subsequent phosphatidyl serine exposure. J Biol Chem 285:15557–15565
    • (2010) J. Biol. Chem , vol.285 , pp. 15557-15565
    • Skals, M.1    Jensen, U.B.2    Ousingsawat, J.3    Kunzelmann, K.4    Leipziger, J.5    Praetorius, H.A.6
  • 146
    • 77954777804 scopus 로고    scopus 로고
    • Cholesterol depletion alters amplitude and pharmacology of vascular calcium-activated chloride channels
    • PID: 2017286
    • Sones WR, Davis AJ, Leblanc N, Greenwood IA (2010) Cholesterol depletion alters amplitude and pharmacology of vascular calcium-activated chloride channels. Cardiovasc Res 87:476–484
    • (2010) Cardiovasc. Res. , vol.87 , pp. 476-484
    • Sones, W.R.1    Davis, A.J.2    Leblanc, N.3    Greenwood, I.A.4
  • 150
  • 151
    • 84919924478 scopus 로고    scopus 로고
    • Inhibition of TMEM16A expression suppresses growth and invasion in human colorectal cancer cells
    • PID: 2554194
    • Sui Y, Sun M, Wu F, Yang L, Di W, Zhang G, Zhong L, Ma Z, Zheng J, Fang X, Ma T (2014) Inhibition of TMEM16A expression suppresses growth and invasion in human colorectal cancer cells. PLoS One 9:e115443
    • (2014) PLoS One , vol.9 , pp. e115443
    • Sui, Y.1    Sun, M.2    Wu, F.3    Yang, L.4    Di, W.5    Zhang, G.6    Zhong, L.7    Ma, Z.8    Zheng, J.9    Fang, X.10    Ma, T.11
  • 152
    • 84864297897 scopus 로고    scopus 로고
    • Chronic hypoxia-induced upregulation of Ca2+-activated Cl- channel in pulmonary arterial myocytes: a mechanism contributing to enhanced vasoreactivity
    • PID: 2267471
    • Sun H, Xia Y, Paudel O, Yang XR, Sham JS (2012) Chronic hypoxia-induced upregulation of Ca2+-activated Cl- channel in pulmonary arterial myocytes: a mechanism contributing to enhanced vasoreactivity. J Physiol 590:3507–3521
    • (2012) J Physiol. , vol.590 , pp. 3507-3521
    • Sun, H.1    Xia, Y.2    Paudel, O.3    Yang, X.R.4    Sham, J.S.5
  • 153
    • 34548203177 scopus 로고    scopus 로고
    • Zn2+ sensitivity of high- and low-voltage activated calcium channels
    • PID: 1752656
    • Sun HS, Hui K, Lee DW, Feng ZP (2007) Zn2+ sensitivity of high- and low-voltage activated calcium channels. Biophys J 93:1175–1183
    • (2007) Biophys. J. , vol.93 , pp. 1175-1183
    • Sun, H.S.1    Hui, K.2    Lee, D.W.3    Feng, Z.P.4
  • 154
    • 84905009302 scopus 로고    scopus 로고
    • Anoctamin 1 calcium-activated chloride channel downregulates estrogen production in mouse ovarian granulosa cells
    • Sun M, Sui Y, Li L, Su W, Hao F, Zhu Q, Di W, Gao H, Ma T (2014) Anoctamin 1 calcium-activated chloride channel downregulates estrogen production in mouse ovarian granulosa cells. Endocrinol 155:2787–2796
    • (2014) Endocrinol , vol.155 , pp. 2787-2796
    • Sun, M.1    Sui, Y.2    Li, L.3    Su, W.4    Hao, F.5    Zhu, Q.6    Di, W.7    Gao, H.8    Ma, T.9
  • 155
    • 84937923307 scopus 로고    scopus 로고
    • Sun Y, Birnbaumer L, and Singh BB (2015) TRPC1 regulates calcium-activated chloride channels in salivary gland cells. J Cell Physiol.(in press)
    • Sun Y, Birnbaumer L, and Singh BB (2015) TRPC1 regulates calcium-activated chloride channels in salivary gland cells. J Cell Physiol.(in press).
  • 156
    • 84880758440 scopus 로고    scopus 로고
    • Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells
    • PID: 2384594
    • Suzuki J, Denning DP, Imanishi E, Horvitz HR, Nagata S (2013) Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells. Science 341:403–406
    • (2013) Science , vol.341 , pp. 403-406
    • Suzuki, J.1    Denning, D.P.2    Imanishi, E.3    Horvitz, H.R.4    Nagata, S.5
  • 157
    • 84877709762 scopus 로고    scopus 로고
    • Calcium-dependent phospholipid scramblase activity of TMEM16 family members
    • PID: 2353283
    • Suzuki J, Fujii T, Imao T, Ishihara K, Kuba H, Nagata S (2013) Calcium-dependent phospholipid scramblase activity of TMEM16 family members. J Biol Chem 288:13305–13316
    • (2013) J Biol Chem. , vol.288 , pp. 13305-13316
    • Suzuki, J.1    Fujii, T.2    Imao, T.3    Ishihara, K.4    Kuba, H.5    Nagata, S.6
  • 158
    • 78650172970 scopus 로고    scopus 로고
    • Calcium-dependent phospholipid scrambling by TMEM16F
    • PID: 2110732
    • Suzuki J, Umeda M, Sims PJ, Nagata S (2010) Calcium-dependent phospholipid scrambling by TMEM16F. Nature 468:834–838
    • (2010) Nature , vol.468 , pp. 834-838
    • Suzuki, J.1    Umeda, M.2    Sims, P.J.3    Nagata, S.4
  • 161
    • 84901049773 scopus 로고    scopus 로고
    • Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1
    • PID: 2450991
    • Takayama Y, Shibasaki K, Suzuki Y, Yamanaka A, Tominaga M (2014) Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1. FASEB J 28:2238–2248
    • (2014) FASEB J. , vol.28 , pp. 2238-2248
    • Takayama, Y.1    Shibasaki, K.2    Suzuki, Y.3    Yamanaka, A.4    Tominaga, M.5
  • 162
    • 84928308934 scopus 로고    scopus 로고
    • Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons
    • PID: 2584805
    • Takayama Y, Uta D, Furue H, Tominaga M (2015) Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons. Proc Natl Acad Sci U S A 112(16):5213–8. doi:10.1073/pnas.1421507112
    • (2015) Proc. Natl. Acad. Sci U. S. A. , vol.112 , Issue.16 , pp. 5213-5218
    • Takayama, Y.1    Uta, D.2    Furue, H.3    Tominaga, M.4
  • 163
    • 0034644626 scopus 로고    scopus 로고
    • Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier
    • PID: 1103065
    • Takizawa PA, DeRisi JL, Wilhelm JE, Vale RD (2000) Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier. Science 290:341–344
    • (2000) Science , vol.290 , pp. 341-344
    • Takizawa, P.A.1    DeRisi, J.L.2    Wilhelm, J.E.3    Vale, R.D.4
  • 164
    • 84888323395 scopus 로고    scopus 로고
    • Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels
    • PID: 2416726
    • Terashima H, Picollo A, Accardi A (2013) Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels. Proc Natl Acad Sci U S A 110:19354–19359
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 19354-19359
    • Terashima, H.1    Picollo, A.2    Accardi, A.3
  • 166
  • 167
    • 84872236421 scopus 로고    scopus 로고
    • Anoctamins are a family of Ca2+ activated Cl- channels
    • PID: 2294605
    • Tian Y, Schreiber R, Kunzelmann K (2012) Anoctamins are a family of Ca2+ activated Cl- channels. J Cell Sci 125:4991–4998
    • (2012) J Cell Sci , vol.125 , pp. 4991-4998
    • Tian, Y.1    Schreiber, R.2    Kunzelmann, K.3
  • 168
    • 84905186544 scopus 로고    scopus 로고
    • A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife
    • Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, and Yang H (2014) A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. doi: 10.7554/eLife.02772.
    • (2014) doi: 10.7554/eLife.02772
    • Tien, J.1    Peters, C.J.2    Wong, X.M.3    Cheng, T.4    Jan, Y.N.5    Jan, L.Y.6    Yang, H.7
  • 169
    • 84886264667 scopus 로고    scopus 로고
    • Tran TT, Tobiume K, Hirono C, Fujimoto S, Mizuta K, Kubozono K, Inoue H, Itakura M, Sugita M, and Kamata N (2014) TMEM16E (GDD1) exhibits protein instability and distinct characteristics in chloride channel/pore forming ability. J. Cell Physiol. (in press) 229: 181-190
    • Tran TT, Tobiume K, Hirono C, Fujimoto S, Mizuta K, Kubozono K, Inoue H, Itakura M, Sugita M, and Kamata N (2014) TMEM16E (GDD1) exhibits protein instability and distinct characteristics in chloride channel/pore forming ability. J. Cell Physiol. (in press) 229: 181-190.
  • 172
    • 84876516813 scopus 로고    scopus 로고
    • Both TMEM16F-dependent and TMEM16F-independent pathways contribute to phosphatidylserine exposure in platelet apoptosis and platelet activation
    • PID: 2330382
    • van Kruchten R, Mattheij NJ, Saunders C, Feijge MA, Swieringa F, Wolfs JL, Collins PW, Heemskerk JW, Bevers EM (2013) Both TMEM16F-dependent and TMEM16F-independent pathways contribute to phosphatidylserine exposure in platelet apoptosis and platelet activation. Blood 121:1850–1857
    • (2013) Blood , vol.121 , pp. 1850-1857
    • van Kruchten, R.1    Mattheij, N.J.2    Saunders, C.3    Feijge, M.A.4    Swieringa, F.5    Wolfs, J.L.6    Collins, P.W.7    Heemskerk, J.W.8    Bevers, E.M.9
  • 174
    • 84871700177 scopus 로고    scopus 로고
    • Functional coupling of TRPC2 cation channels and the calcium-activated anion channels in rat thyroid cells: implications for iodide homeostasis
    • Viitanen T, Sukumaran P, Lof C, Tornquist K (2012) Functional coupling of TRPC2 cation channels and the calcium-activated anion channels in rat thyroid cells: implications for iodide homeostasis. J Cell Physiol 228:814–823
    • (2012) J Cell Physiol. , vol.228 , pp. 814-823
    • Viitanen, T.1    Sukumaran, P.2    Lof, C.3    Tornquist, K.4
  • 178
    • 84924576156 scopus 로고    scopus 로고
    • Overexpression of ANO1/TMEM16A, an arterial Ca(2+)-activated Cl(-) channel, contributes to spontaneous hypertension
    • PID: 2573900
    • Wang B, Li C, Huai R, Qu Z (2015) Overexpression of ANO1/TMEM16A, an arterial Ca(2+)-activated Cl(-) channel, contributes to spontaneous hypertension. J Mol Cell Cardiol 82:22–32
    • (2015) J Mol. Cell Cardiol. , vol.82 , pp. 22-32
    • Wang, B.1    Li, C.2    Huai, R.3    Qu, Z.4
  • 179
    • 84878219975 scopus 로고    scopus 로고
    • Purinergic regulation of CFTR and Ca2+-activated Cl- channels and K+ channels in human pancreatic duct epithelium
    • PID: 2336426
    • Wang J, Haanes KA, Novak I (2013) Purinergic regulation of CFTR and Ca2+-activated Cl- channels and K+ channels in human pancreatic duct epithelium. Am J Physiol Cell Physiol 304:C673–C684
    • (2013) Am. J Physiol Cell Physiol , vol.304 , pp. C673-C684
    • Wang, J.1    Haanes, K.A.2    Novak, I.3
  • 180
    • 84863150267 scopus 로고    scopus 로고
    • Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension through promoting basilar smooth muscle cell proliferation
    • PID: 2221585
    • Wang M, Yang H, Zheng LY, Zhang Z, Tang YB, Wang GL, Du YH, Lv XF, Liu J, Zhou JG, Guan YY (2012) Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension through promoting basilar smooth muscle cell proliferation. Circulation 125:697–707
    • (2012) Circulation , vol.125 , pp. 697-707
    • Wang, M.1    Yang, H.2    Zheng, L.Y.3    Zhang, Z.4    Tang, Y.B.5    Wang, G.L.6    Du, Y.H.7    Lv, X.F.8    Liu, J.9    Zhou, J.G.10    Guan, Y.Y.11
  • 182
    • 84881553837 scopus 로고    scopus 로고
    • Anoctamin 5 muscular dystrophy in Denmark: prevalence, genotypes, phenotypes, cardiac findings, and muscle protein expression
    • PID: 2367030
    • Witting N, Duno M, Petri H, Krag T, Bundgaard H, Kober L, Vissing J (2013) Anoctamin 5 muscular dystrophy in Denmark: prevalence, genotypes, phenotypes, cardiac findings, and muscle protein expression. J Neurol 260:2084–2093
    • (2013) J Neurol. , vol.260 , pp. 2084-2093
    • Witting, N.1    Duno, M.2    Petri, H.3    Krag, T.4    Bundgaard, H.5    Kober, L.6    Vissing, J.7
  • 183
    • 84863611406 scopus 로고    scopus 로고
    • Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment
    • PID: 2280805
    • Wolf W, Kilic A, Schrul B, Lorenz H, Schwappach B, Seedorf M (2012) Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment. PLoS One 7:e39703
    • (2012) PLoS One , vol.7 , pp. e39703
    • Wolf, W.1    Kilic, A.2    Schrul, B.3    Lorenz, H.4    Schwappach, B.5    Seedorf, M.6
  • 184
    • 84887386469 scopus 로고    scopus 로고
    • Subdued, a TMEM16 family Ca2+-activated Cl- channel in Drosophila melanogaster with an unexpected role in host defense
    • PID: 2419203
    • Wong XM, Younger S, Peters CJ, Jan YN, Jan LY (2013) Subdued, a TMEM16 family Ca2+-activated Cl- channel in Drosophila melanogaster with an unexpected role in host defense. Elife 2:e00862
    • (2013) Elife , vol.2 , pp. e00862
    • Wong, X.M.1    Younger, S.2    Peters, C.J.3    Jan, Y.N.4    Jan, L.Y.5
  • 185
    • 79957786620 scopus 로고    scopus 로고
    • Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop
    • PID: 2155558
    • Xiao Q, Yu K, Perez-Cornejo P, Cui Y, Arreola J, Hartzell HC (2011) Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci U S A 108:8891–8896
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 8891-8896
    • Xiao, Q.1    Yu, K.2    Perez-Cornejo, P.3    Cui, Y.4    Arreola, J.5    Hartzell, H.C.6
  • 186
    • 84863687970 scopus 로고    scopus 로고
    • Activity of Ca -activated Cl channels contributes to regulating receptor- and store-operated Ca entry in human pulmonary artery smooth muscle cells
    • PID: 2203461
    • Yamamura A, Yamamura H, Zeifman A, Yuan JX (2011) Activity of Ca -activated Cl channels contributes to regulating receptor- and store-operated Ca entry in human pulmonary artery smooth muscle cells. Pulm Circ 1:269–279
    • (2011) Pulm. Circ. , vol.1 , pp. 269-279
    • Yamamura, A.1    Yamamura, H.2    Zeifman, A.3    Yuan, J.X.4
  • 187
    • 84871860558 scopus 로고    scopus 로고
    • TMEM16F forms a Ca(2+)-activated cation channel required for lipid scrambling in platelets during blood coagulation
    • PID: 2302121
    • Yang H, Kim A, David T, Palmer D, Jin T, Tien J, Huang F, Cheng T, Coughlin SR, Jan YN, Jan LY (2012) TMEM16F forms a Ca(2+)-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell 151:111–122
    • (2012) Cell. , vol.151 , pp. 111-122
    • Yang, H.1    Kim, A.2    David, T.3    Palmer, D.4    Jin, T.5    Tien, J.6    Huang, F.7    Cheng, T.8    Coughlin, S.R.9    Jan, Y.N.10    Jan, L.Y.11
  • 188
    • 84900444758 scopus 로고    scopus 로고
    • Chloroquine stimulates Cl(-) secretion by Ca(2+) activated Cl(-) channels in rat ileum
    • PID: 2449815
    • Yang N, Lei Z, Li X, Zhao J, Liu T, Ning N, Xiao A, Xu L, Li J (2014) Chloroquine stimulates Cl(-) secretion by Ca(2+) activated Cl(-) channels in rat ileum. PLoS One 9:e87627
    • (2014) PLoS One , vol.9 , pp. e87627
    • Yang, N.1    Lei, Z.2    Li, X.3    Zhao, J.4    Liu, T.5    Ning, N.6    Xiao, A.7    Xu, L.8    Li, J.9
  • 189
    • 84919897860 scopus 로고    scopus 로고
    • Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels
    • PID: 2548908
    • Yang T, Hendrickson WA, Colecraft HM (2014) Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels. Proc Natl Acad Sci U S A 111:18213–18218
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , pp. 18213-18218
    • Yang, T.1    Hendrickson, W.A.2    Colecraft, H.M.3
  • 191
    • 84907533247 scopus 로고    scopus 로고
    • Developmental role of anoctamin-1/TMEM16A in Ca(2+)-dependent volume change in supporting cells of the mouse cochlea
    • PID: 2446514
    • Yi E, Lee J, Lee CJ (2013) Developmental role of anoctamin-1/TMEM16A in Ca(2+)-dependent volume change in supporting cells of the mouse cochlea. Exp Neurobiol 22:322–329
    • (2013) Exp. Neurobiol. , vol.22 , pp. 322-329
    • Yi, E.1    Lee, J.2    Lee, C.J.3
  • 193
    • 84859435658 scopus 로고    scopus 로고
    • Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology
    • PID: 2239451
    • Yu K, Duran C, Qu Z, Cui YY, Hartzell HC (2012) Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology. Circ Res 110:990–999
    • (2012) Circ. Res. , vol.110 , pp. 990-999
    • Yu, K.1    Duran, C.2    Qu, Z.3    Cui, Y.Y.4    Hartzell, H.C.5
  • 194
    • 84933046969 scopus 로고    scopus 로고
    • Identification of a lipid scrambling domain in ANO6/TMEM16F
    • PID: 2605782
    • Yu K, Whitlock JM, Lee K, Ortlund EA, Yuan CY, Hartzell HC (2015) Identification of a lipid scrambling domain in ANO6/TMEM16F. Elife 4:e06901. doi:10.7554/eLife.06901
    • (2015) Elife. , vol.4 , pp. e06901
    • Yu, K.1    Whitlock, J.M.2    Lee, K.3    Ortlund, E.A.4    Yuan, C.Y.5    Hartzell, H.C.6
  • 195
    • 84893141356 scopus 로고    scopus 로고
    • Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin
    • PID: 2442077
    • Yu K, Zhu J, Qu Z, Cui YY, Hartzell HC (2014) Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin. J Gen Physiol 143:253–267
    • (2014) J Gen. Physiol. , vol.143 , pp. 253-267
    • Yu, K.1    Zhu, J.2    Qu, Z.3    Cui, Y.Y.4    Hartzell, H.C.5
  • 197
    • 84873974893 scopus 로고    scopus 로고
    • The transmembrane protein 16A Ca(2+)-activated Cl- channel in airway smooth muscle contributes to airway hyperresponsiveness
    • PID: 2323915
    • Zhang CH, Li Y, Zhao W, Lifshitz LM, Li H, Harfe BD, Zhu MS, ZhuGe R (2013) The transmembrane protein 16A Ca(2+)-activated Cl- channel in airway smooth muscle contributes to airway hyperresponsiveness. Am J Respir Crit Care Med 187:374–381
    • (2013) Am J Respir. Crit Care Med. , vol.187 , pp. 374-381
    • Zhang, C.H.1    Li, Y.2    Zhao, W.3    Lifshitz, L.M.4    Li, H.5    Harfe, B.D.6    Zhu, M.S.7    ZhuGe, R.8
  • 200
    • 84929996502 scopus 로고    scopus 로고
    • TMEM16A-mediated mucin secretion in IL-13-induced nasal epithelial cells from chronic rhinosinusitis patients
    • PID: 2574977
    • Zhang Y, Wang X, Wang H, Jiao J, Li Y, Fan E, Zhang L, Bachert C (2015) TMEM16A-mediated mucin secretion in IL-13-induced nasal epithelial cells from chronic rhinosinusitis patients. Allergy Asthma Immunol Res 7:367–375
    • (2015) Allergy Asthma Immunol. Res. , vol.7 , pp. 367-375
    • Zhang, Y.1    Wang, X.2    Wang, H.3    Jiao, J.4    Li, Y.5    Fan, E.6    Zhang, L.7    Bachert, C.8
  • 202
    • 76249119259 scopus 로고    scopus 로고
    • Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle
    • PID: 1992013
    • ZhuGe R, Bao R, Fogarty KE, Lifshitz LM (2010) Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle. J Biol Chem 285:2203–2210
    • (2010) J Biol Chem. , vol.285 , pp. 2203-2210
    • ZhuGe, R.1    Bao, R.2    Fogarty, K.E.3    Lifshitz, L.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.