Escherichia coli α-hemolysin triggers shrinkage of erythrocytes via KCa3.1 and TMEM16A channels with subsequent phosphatidylserine exposure

Journal of Biological Chemistry

Volumn 285, Issue 20, 2010, Pages 15557-15565

  Skals, Marianne ^a   Jensen, Uffe B ^a   Ousingsawat, Jiraporn ^b   Kunzelmann, Karl ^b   Leipziger, Jens ^a   Praetorius, Helle A ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL VOLUME; HUMAN ERYTHROCYTES; INTRAVASCULAR; PHOSPHATIDYLSERINE; PLASMA MEMBRANES; PORE FORMING TOXINS; UNDERLYING MECHANISM; VOLUME REDUCTIONS;

BLOOD; CELL MEMBRANES; ESCHERICHIA COLI; SHRINKAGE;

CALCIUM;

ALPHA HEMOLYSIN; AQUAPORIN; CALCIUM ACTIVATED CHLORIDE CHANNEL; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; CHLORIDE CHANNEL; CHLORIDE ION; CLOTRIMAZOLE; PHOSPHATIDYLSERINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL ISOLATION; CELL MEMBRANE; CELL SWELLING; CHANNEL GATING; CONTROLLED STUDY; ERYTHROCYTE VOLUME; ESCHERICHIA COLI; GRAM NEGATIVE SEPSIS; HEMOLYSIS; HUMAN; HUMAN CELL; INTRAVASCULAR HEMOLYSIS; MACROPHAGE; MOUSE; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL;

ANIMALS; CELL SIZE; CELLS, CULTURED; ERYTHROCYTES; ESCHERICHIA COLI PROTEINS; FLOW CYTOMETRY; HEMOLYSIN PROTEINS; HEMOLYSIS; HUMANS; MEMBRANE PROTEINS; MICE; NEOPLASM PROTEINS; PHOSPHATIDYLSERINES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED;

ESCHERICHIA COLI; MUS;

EID: 77952029786     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.082578     Document Type: Article

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