Sinupret activates CFTR and TMEM16A-dependent transepithelial chloride transport and improves indicators of mucociliary clearance

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Zhang, Shaoyan ^a,b   Skinner, Daniel ^a,b   Hicks, Stephen Bradley ^a   Bevensee, Mark O ^b,c   Sorscher, Eric J ^b,d   Lazrak, Ahmed ^e   Matalon, Sadis ^e   McNicholas, Carmel M ^c   Woodworth, Bradford A ^a,c  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d University of Alabama at Birmingham   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANO1 PROTEIN, HUMAN; CALCIUM; CHLORIDE; CHLORIDE CHANNEL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; PLANT EXTRACT; SINUPRET; TMEM16A PROTEIN, MOUSE; TUMOR PROTEIN;

ANIMAL; CHEMISTRY; DRUG EFFECTS; EPITHELIUM CELL; EUKARYOTIC FLAGELLUM; GENETICS; HUMAN; ION TRANSPORT; METABOLISM; MOUSE; MUCOCILIARY CLEARANCE; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CHLORIDE CHANNELS; CHLORIDES; CILIA; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; HUMANS; ION TRANSPORT; MICE; MUCOCILIARY CLEARANCE; NEOPLASM PROTEINS; PATCH-CLAMP TECHNIQUES; PLANT EXTRACTS; PROTEIN INTERACTION DOMAINS AND MOTIFS; SIGNAL TRANSDUCTION;

EID: 84905899119     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0104090     Document Type: Article

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