Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 51, 2014, Pages 18213-18218

  Yang, Tingting ^a   Hendrickson, Wayne A ^a,b   Colecraft, Henry M ^b  

^a Department of Biochemistry and Molecular Biophysics Columbia University ^*  (United States)

^b Department of Physiology and Cellular Biophysics College of Physicians and Surgeons Columbia University ^*  (United States)

Author keywords

Anoctamin1; Calcium activated chloride channel; Calmodulin; TMEM16A

Indexed keywords

CALCIUM ION; CALMODULIN; CHLORIDE CHANNEL; MEMBRANE PROTEIN; PROTEIN; TMEM16A PROTEIN; TMEM16B PROTEIN; UNCLASSIFIED DRUG; ANO1 PROTEIN, HUMAN; CALCIUM; TMEM16B PROTEIN, HUMAN; TUMOR PROTEIN;

ALTERNATIVE RNA SPLICING; ARTICLE; BIOENGINEERING; COMPLEX FORMATION; CONTROLLED STUDY; GENE INACTIVATION; HOMEOSTASIS; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SENSITIZATION; ANTAGONISTS AND INHIBITORS; CHANNEL GATING; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; RNA SPLICING;

CALCIUM; CALMODULIN; CHLORIDE CHANNELS; HUMANS; ION CHANNEL GATING; MEMBRANE PROTEINS; NEOPLASM PROTEINS; RNA SPLICING;

EID: 84919897860     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420984111     Document Type: Article

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