TRPC1 regulates calcium-activated chloride channels in salivary gland cells

Journal of Cellular Physiology

Volumn 230, Issue 11, 2015, Pages 2848-2856

  Sun, Yuyang ^a   Birnbaumer, Lutz ^b   Singh, Brij B ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED CHLORIDE CHANNEL; CALCIUM ION; CELL MEMBRANE PROTEIN; NIFLUMIC ACID; THAPSIGARGIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSMEMBRANE PROTEINS OF UNKNOWN FUNCTION 16; UNCLASSIFIED DRUG; ANO1 PROTEIN, HUMAN; CALCIUM; CHLORIDE CHANNEL; PYRIMIDINE DERIVATIVE; T16AINH-A01; THIAZOLE DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY C, MEMBER 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TUMOR PROTEIN;

ACINAR CELL; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL ISOLATION; CELL STIMULATION; CHLORIDE CURRENT; CONTROLLED STUDY; EXOCRINE CELL; GENE SILENCING; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIMARY CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SALIVARY GLAND; SALIVARY GLAND CELL; SALIVATION; SUBMANDIBULAR GLAND; ANIMAL; ANTAGONISTS AND INHIBITORS; CALCIUM SIGNALING; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

MUS;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CHLORIDE CHANNELS; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, KNOCKOUT; NEOPLASM PROTEINS; NIFLUMIC ACID; PYRIMIDINES; SALIVARY GLANDS; THIAZOLES; TRPC CATION CHANNELS;

EID: 84937923307     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.25017     Document Type: Article

References (34)

1. Ambudkar IS. 2012. Polarization of calcium signaling and fluid secretion in salivary gland cells. Curr Med Chem 19:5774-5781.
2. Caputo A, Caci E, Ferrera L, Pedemonte N, Barsanti C, Sondo E, Pfeffer U, Ravazzolo R, Zegarra-Moran O, Galietta LJ. 2008. TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science 322:590-594.
3. Catalan MA, Kondo Y, Pena-Munzenmayer G, Jaramillo Y, Liu F, Choi S, Crandall E, Borok Z, Flodby P, Shull GE, Melvin JE. 2015. A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland. Proc Natl Acad Sci USA 112:2263-2268.
4. Cho HJ, Park SM, Kim IK, Nam IK, Baek KE, Im MJ, Yoo JM, Park SH, Ryu KJ, Han HT, Kim HJ, Hong SC, Kim KD, Pak Y, Kim JW, Lee CW, Yoo J. 2014. RhoGDI2 promotes epithelial-mesenchymal transition via induction of Snail in gastric cancer cells. Oncotarget 5:1554-1564.
5. Davis AJ, Shi J, Pritchard HA, Chadha PS, Leblanc N, Vasilikostas G, Yao Z, Verkman AS, Albert AP, Greenwood IA. 2013. Potent vasorelaxant activity of the TMEM16A inhibitor T16A(inh) - A01. Br J Pharmacol 168:773-784.
6. Ferrera L, Caputo A, Galietta LJ. 2010. TMEM16A protein: A new identity for Ca(2+)-dependent Cl(-) channels. Physiology 25:357-363.
7. Ferrera L, Zegarra-Moran O, Galietta LJ. 2011. Ca2+-activated Cl-channels. Compre Physiol 1:2155-2174.
8. Frizzell RA, Hanrahan JW. 2012. Physiology of epithelial chloride and fluid secretion. Cold Spring Harb Perspect Med 2:a009563.
9. Futatsugi A, Nakamura T, Yamada MK, Ebisui E, Nakamura K, Uchida K, Kitaguchi T, Takahashi-Iwanaga H, Noda T, Aruga J, Mikoshiba K. 2005. IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Science 309, 2232-2234.
10. Galan C, Dionisio N, Smani T, Salido GM, Rosado JA. 2011. The cytoskeleton plays a modulatory role in the association between STIM1 and the Ca2+ channel subunits Orai1 and TRPC1. Biochem Pharmacol 82:400-410.
11. Hartzell C, Putzier I, Arreola J. 2005. Calcium-activated chloride channels. Annu Rev Physiol 67:719-758.
12. Huang F, Rock JR, Harfe BD, Cheng T, Huang X, Jan YN, Jan LY. 2009. Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci USA 106:21413-21418.
13. Huang F, Wong X, Jan LY. 2012. International union of basic and clinical pharmacology. LXXXV: Calcium-activated chloride channels. Pharmacol Rev 64:1-15.
14. Jung J, Nam JH, Park HW, Oh U, Yoon JH, Lee MG. 2013. Dynamic modulation of ANO1/TMEM16A HCO3(-) permeability by Ca2+/calmodulin. Proc Natl Acad Sci USA 110:360-365.
15. Lee RJ, Foskett JK. 2010. Mechanisms of Ca2+-stimulated fluid secretion by porcine bronchial submucosal gland serous acinar cells. Am J Physiol Lung Cell Mol Physiol 298:L210-231.
16. Liu X, Cheng KT, Bandyopadhyay BC, Pani B, Dietrich A, Paria BC, Swaim WD, Beech D, Yildrim E, Singh BB, Birnbaumer L, Ambudkar IS. 2007. Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice. Proc Natl Acad Sci USA 104:17542-17547.
17. Liu X, Ong HL, Pani B, Johnson K, Swaim WB, Singh B, Ambudkar I. 2010. Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE. Cell Calcium 47:491-499.
18. Liu X, Singh BB, Ambudkar IS. 2003. TRPC1 is required for functional store-operated Ca2+ channels. Role of acidic amino acid residues in the S5-S6 region. J Biol Chem 278:11337-11343.
19. Liu X, Wang W, Singh BB, Lockwich T, Jadlowiec J, O'Connell B, Wellner R, Zhu MX, Ambudkar IS. 2000. Trp1, a candidate protein for the store-operated Ca(2+) influx mechanism in salivary gland cells. J Biol Chem 275:3403-3411.
20. Melvin JE, Yule D, Shuttleworth T, Begenisich T. 2005. Regulation of fluid and electrolyte secretion in salivary gland acinar cells. Annu Rev Physiol 67:445-469.
21. Ong HL, Cheng KT, Liu X, Bandyopadhyay BC, Paria BC, Soboloff J, Pani B, Gwack Y, Srikanth S, Singh BB, Gill DL, Ambudkar IS. 2007. Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. J Biol Chem 282:9105-9116.
22. Ousingsawat J, Martins JR, Schreiber R, Rock JR, Harfe BD, Kunzelmann K. 2009. Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem 284:28698-28703.
23. Pang C, Yuan H, Ren S, Chen Y, An H, Zhan Y. 2014. TMEM16A/B associated CaCC: Structural and functional insights. Protein Pept Lett 21:94-99.
24. Pani B, Liu X, Bollimuntha S, Cheng KT, Niesman IR, Zheng C, Achen VR, Patel HH, Ambudkar IS, Singh BB. 2013. Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1. J Cell Sci 126:667-675.
25. Pedemonte N, Galietta LJ. 2014. Structure and function of TMEM16 proteins (anoctamins). Physiol Rev 94:419-459.
26. Romanenko VG, Catalan MA, Brown DA, Putzier I, Hartzell HC, Marmorstein AD, Gonzalez-Begne M, Rock JR, Harfe BD, Melvin JE. 2010. Tmem16A encodes the Ca2+-activated Cl-channel in mouse submandibular salivary gland acinar cells. J Biol Chem 285:12990-13001.
27. Roussa E. 2011. Channels and transporters in salivary glands. Cell Tissue Res 343:263-287.
28. Schroeder BC, Cheng T, Jan YN, Jan LY. 2008. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell 134:1019-1029.
29. 2+ influx by interaction with a site in the C-terminus of TRPC1. Mol Cell 9:739-750.
30. Sun Y, Sukumaran P, Varma A, Derry S, Sahmoun AE, Singh BB. 2014. Cholesterol-induced activation of TRPM7 regulates cell proliferation, migration, and viability of human prostate cells. Biochim Biophys Acta 1843:1839-1850.
31. Takayama Y, Shibasaki K, Suzuki Y, Yamanaka A, Tominaga M. 2014. Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1. Faseb J 28:2238-2248.
32. Thomas-Gatewood C, Neeb ZP, Bulley S, Adebiyi A, Bannister JP, Leo MD, Jaggar JH. 2011. TMEM16A channels generate Ca(2)(+)-activated Cl(-) currents in cerebral artery smooth muscle cells. Am J Physiol Heart Circ Physiol 301:H1819-1827.
33. Viitanen TM, Sukumaran P, Lof C, Tornquist K. 2013. Functional coupling of TRPC2 cation channels and the calcium-activated anion channels in rat thyroid cells: Implications for iodide homeostasis. J Cell Physiol 228:814-823.
34. Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh U. 2008. TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature 455:1210-1215.