Activity of Ca2+-activated Cl- channels contributes to regulating receptor- and store-operated Ca2+ entry in human pulmonary artery smooth muscle cells

Pulmonary Circulation

Volumn 1, Issue 2, 2011, Pages 269-279

  Yamamura, Aya ^a   Yamamura, Hisao ^a   Zeifman, Amy ^a   Yuan, Jason X J ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Angiotensin II; Ca2+ signaling; Ca2+ activated Cl current; Niflumic acid; TMEM16A

Indexed keywords

EID: 84863687970     PISSN: 20458932     EISSN: 20458940     Source Type: Journal    
DOI: 10.4103/2045-8932.83447     Document Type: Article

References (56)

1. Firth AL, Remillard CV, Yuan JX. TRP channels in hypertension. Biochim Biophys Acta 2007;1772:895-906.
2. Morrell NW, Adnot S, Archer SL, Dupuis J, Jones PL, MacLean MR, et al. Cellular and molecular basis of pulmonary arterial hypertension. J Am Coll Cardiol 2009;54:S20-31.
3. Firth AL, Remillard CV, Platoshyn O, Fantozzi I, Ko EA, Yuan JX. Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels. Pulm Circ 2011;1:48-71.
4. + current in rat intrapulmonary arterial myocytes by endothelin-1. Am J Physiol 1998;274:L842-53.
5. Pitt BR, Weng W, Steve AR, Blakely RD, Reynolds I, Davies P. Serotonin increases DNA synthesis in rat proximal and distal pulmonary vascular smooth muscle cells in culture. Am J Physiol 1994;266:L178-86.
6. 2+ entry and tyrosine kinase activation in canine pulmonary arterial smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2000;278:L118-30.
7. 2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells. Am J Physiol Cell Physiol 2006;290:C325-36.
8. Ohlstein EH, Douglas SA, Sung CP, Yue TL, Louden C, Arleth A, et al. Carvedilol, a cardiovascular drug, prevents vascular smooth muscle cell proliferation, migration, and neointimal formation following vascular injury. Proc Natl Acad Sci USA 1993;90:6189-93.
9. Yu Y, Sweeney M, Zhang S, Platoshyn O, Landsberg J, Rothman A, et al. PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression. Am J Physiol Cell Physiol 2003;284:C316-30.
10. Yang XR, Lin MJ, Sham JS. Physiological functions of transient receptor potential channels in pulmonary arterial smooth muscle cells. Adv Exp Med Biol 2010;661:109-22.
11. Wang Y, Deng X, Hewavitharana T, Soboloff J, Gill DL. Stim, ORAI and TRPC channels in the control of calcium entry signals in smooth muscle. Clin Exp Pharmacol Physiol 2008;35:1127-33.
12. Albert AP, Saleh SN, Peppiatt-Wildman CM, Large WA. Multiple activation mechanisms of store-operated TRPC channels in smooth muscle cells. J Physiol 2007;583:25-36.
13. 2+ entry and attenuates pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol 2002;283:L144-55.
14. 2+ entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol 2001;280:H746-55.
15. 2+-activated Cl-conductance in smooth muscle. Am J Physiol 1996;271:C435-54.
16. Leblanc N, Ledoux J, Saleh S, Sanguinetti A, Angermann J, O’Driscoll K, et al. Regulation of calcium-activated chloride channels in smooth muscle cells: a complex picture is emerging. Can J Physiol Pharmacol 2005;83:541-56.
17. Chipperfield AR, Harper AA. Chloride in smooth muscle. Prog Biophys Mol Biol 2000;74:175-221.
18. Caputo A, Caci E, Ferrera L, Pedemonte N, Barsanti C, Sondo E, et al. TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science 2008;322:590-4.
19. Schroeder BC, Cheng T, Jan YN, Jan LY. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell 2008;134:1019-29.
20. Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, et al. TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature 2008;455:1210-5.
21. Cornfield DN, Stevens T, McMurtry IF, Abman SH, Rodman DM. Acute hypoxia increases cytosolic calcium in fetal pulmonary artery smooth muscle cells. Am J Physiol 1993;265:L53-6.
22. Bonnet S, Belus A, Hyvelin JM, Roux E, Marthan R, Savineau JP. Effect of chronic hypoxia on agonist-induced tone and calcium signaling in rat pulmonary artery. Am J Physiol Lung Cell Mol Physiol 2001;281:L193-201.
23. Gögelein H, Dahlem D, Englert HC, Lang HJ. Flufenamic acid, mefenamic acid and niflumic acid inhibit single nonselective cation channels in the rat exocrine pancreas. FEBS Lett 1990;268:79-82.
24. Ottolia M, Toro L. Potentiation of large conductance KCa channels by niflumic, flufenamic, and mefenamic acids. Biophys J 1994;67:2272-9.
25. Foster RR, Zadeh MA, Welsh GI, Satchell SC, Ye Y, Mathieson PW, et al. Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells. Cell Calcium 2009;45:384-90.
26. Fuchs B, Dietrich A, Gudermann T, Kalwa H, Grimminger F, Weissmann N. The role of classical transient receptor potential channels in the regulation of hypoxic pulmonary vasoconstriction. Adv Exp Med Biol 2010;661:187-200.
27. 2+ responses to hypoxia. Am J Physiol Lung Cell Mol Physiol 2008;295:L104-13.
28. 2+ entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Pulm Circ 2011;1:84-94.
29. 2+ entry in mouse pulmonary arterial smooth muscle cells. J Physiol 2009;587:2429-42.
30. Jung S, Strotmann R, Schultz G, Plant TD. TRPC6 is a candidate channel involved in receptor-stimulated cation currents in A7r5 smooth muscle cells. Am J Physiol Cell Physiol 2002;282:C347-59.
31. Tai K, Hamaide MC, Debaix H, Gailly P, Wibo M, Morel N. Agonist-evoked calcium entry in vascular smooth muscle cells requires IP3 receptor-mediated activation of TRPC1. Eur J Pharmacol 2008;583:135-47.
32. Maruyama Y, Nakanishi Y, Walsh EJ, Wilson DP, Welsh DG, Cole WC. Heteromultimeric TRPC6-TRPC7 channels contribute to arginine vasopressin-induced cation current of A7r5 vascular smooth muscle cells. Circ Res 2006;98:1520-7.
33. 2+ entry and transient receptor potential canonical and vanilloid-related proteins in rat distal pulmonary venous smooth muscle. Am J Physiol Lung Cell Mol Physiol 2010;299:L621-30.
34. 2+ channels in native vascular smooth muscle cells. Circ Res 2001;88:84-7.
35. 2+ entry in vascular smooth muscle cells. J Pharmacol Exp Ther 2006;317:488-99.
36. 2+ entry in agonist-induced pulmonary vasoconstriction. Am J Physiol Lung Cell Mol Physiol 2001;280:L870-80.
37. 2+ channels in pulmonary arterial smooth muscle cells: A novel mechanism of hypoxic pulmonary hypertension. Circ Res 2004;95:496-505.
38. 2+ influx and contraction in rat pulmonary artery. Circ Res 2001;89:923-9.
39. Hassoun PM, Mouthon L, Barberá JA, Eddahibi S, Flores SC, Grimminger F, et al. Inflammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol 2009;54:S10-9.
40. 2+-calmodulin-dependent kinase. J Physiol 2001;534:395-408.
41. Yuan XJ. Role of calcium-activated chloride current in regulating pulmonary vasomotor tone. Am J Physiol 1997;272:L959-68.
42. Manoury B, Tamuleviciute A, Tammaro P. TMEM16A/anoctamin 1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells. J Physiol 2010;588:2305-14.
43. 2+-activated Cl-channels. J Physiol 2009;587:2127-39.
44. Hwang SJ, Blair PJ, Britton FC, O’Driscoll KE, Hennig G, Bayguinov YR, et al. Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles. J Physiol 2009;587:4887-904.
45. Huang F, Rock JR, Harfe BD, Cheng T, Huang X, Jan YN, et al. Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci USA 2009;106:21413-8.
46. 2+-activated Cl-conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity. J Physiol 2009;587:4905-18.
47. 2+-regulated Cl-secretory channel in mouse airways. J Biol Chem 2009;284:14875-80.
48. 2+-dependent chloride transport. J Biol Chem 2009;284:28698-703.
49. Davis AJ, Forrest AS, Jepps TA, Valencik ML, Wiwchar M, Singer CA, et al. Expression profile and protein translation of TMEM16A in murine smooth muscle. Am J Physiol Cell Physiol 2010;299:C948-59.
50. Gomez-Pinilla PJ, Gibbons SJ, Bardsley MR, Lorincz A, Pozo MJ, Pasricha PJ, et al. Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol 2009;296:G1370-81.
51. Ferrera L, Caputo A, Ubby I, Bussani E, Zegarra-Moran O, Ravazzolo R, et al. Regulation of TMEM16A chloride channel properties by alternative splicing. J Biol Chem 2009;284:33360-8.
52. Stöhr H, Heisig JB, Benz PM, Schöberl S, Milenkovic VM, Strauss O, et al. TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals. J Neurosci 2009;29:6809-18.
53. Pifferi S, Dibattista M, Menini A. TMEM16B induces chloride currents activated by calcium in mammalian cells. Pflügers Arch 2009;458:1023-38.
54. Stephan AB, Shum EY, Hirsh S, Cygnar KD, Reisert J, Zhao H. ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification. Proc Natl Acad Sci USA 2009;106:11776-81.
55. Forrest AS, Angermann JE, Raghunathan R, Lachendro C, Greenwood IA, Leblanc N. Intricate interaction between store-operated calcium entry and calcium-activated chloride channels in pulmonary artery smooth muscle cells. Adv Exp Med Biol 2010;661:31-55.
56. Liang W, Ray JB, He JZ, Backx PH, Ward ME. Regulation of proliferation and membrane potential by chloride currents in rat pulmonary artery smooth muscle cells. Hypertension 2009;54:286-93.