-
2
-
-
77956058729
-
Epigenetics and cardiovascular disease
-
Ordovás JM, Smith CE. Epigenetics and cardiovascular disease. Nat Rev Cardiol. 2010;7:510-519. doi: 10.1038/nrcardio.2010.104.
-
(2010)
Nat Rev Cardiol
, vol.7
, pp. 510-519
-
-
Ordovás, J.M.1
Smith, C.E.2
-
3
-
-
79952805247
-
Cardiovascular epigenetics: Basic concepts and results from animal and human studies
-
Baccarelli A, Rienstra M, Benjamin EJ. Cardiovascular epigenetics: basic concepts and results from animal and human studies. Circ Cardiovasc Genet. 2010;3:567-573. doi: 10.1161/CIRCGENETICS.110.958744.
-
(2010)
Circ Cardiovasc Genet
, vol.3
, pp. 567-573
-
-
Baccarelli, A.1
Rienstra, M.2
Benjamin, E.J.3
-
4
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet. 2003;33:245-254. doi: 10.1038/ng1089.
-
(2003)
Nat Genet
, vol.33
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
5
-
-
66549125217
-
MicroRNAs: Regulating a change of heart
-
Barringhaus KG, Zamore PD. MicroRNAs: regulating a change of heart. Circulation. 2009;119:2217-2224. doi: 10.1161/CIRCULATIONAHA. 107.715839.
-
(2009)
Circulation
, vol.119
, pp. 2217-2224
-
-
Barringhaus, K.G.1
Zamore, P.D.2
-
6
-
-
59749094084
-
Epigenetic histone acetylation modifiers in vascular remodelling: New targets for therapy in cardiovascular disease
-
Pons D, de Vries FR, van den Elsen PJ, Heijmans BT, Quax PH, Jukema JW. Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease. Eur Heart J. 2009;30:266-277. doi: 10.1093/eurheartj/ehn603.
-
(2009)
Eur Heart J
, vol.30
, pp. 266-277
-
-
Pons, D.1
De Vries, F.R.2
Van Den Elsen, P.J.3
Heijmans, B.T.4
Quax, P.H.5
Jukema, J.W.6
-
7
-
-
70149121045
-
MicroRNAs and ischemic heart disease: Towards a better comprehension of pathogenesis, new diagnostic tools and new therapeutic targets
-
Silvestri P, Di Russo C, Rigattieri S, Fedele S, Todaro D, Ferraiuolo G, Altamura G, Loschiavo P. MicroRNAs and ischemic heart disease: towards a better comprehension of pathogenesis, new diagnostic tools and new therapeutic targets. Recent Pat Cardiovasc Drug Discov. 2009;4:109-118.
-
(2009)
Recent Pat Cardiovasc Drug Discov
, vol.4
, pp. 109-118
-
-
Silvestri, P.1
Di Russo, C.2
Rigattieri, S.3
Fedele, S.4
Todaro, D.5
Ferraiuolo, G.6
Altamura, G.7
Loschiavo, P.8
-
8
-
-
84931480038
-
Michels KB
-
Maastricht, Netherlands: Springer
-
Michels KB, ed. Epigenetic Epidemiology. Maastricht, Netherlands: Springer; 2012.
-
(2012)
Epigenetic Epidemiology
-
-
-
9
-
-
33847032960
-
The mammalian epigenome
-
Bernstein BE, Meissner A, Lander ES. The mammalian epigenome. Cell. 2007;128:669-681. doi: 10.1016/j.cell.2007.01.033.
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
10
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. Translating the histone code. Science. 2001;293:1074-1080. doi: 10.1126/science.1063127.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
11
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development
-
Li E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet. 2002;3:662-673. doi: 10.1038/nrg887.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 662-673
-
-
Li, E.1
-
12
-
-
17444409344
-
Epigenetic reprogramming in mammals
-
Morgan HD, Santos F, Green K, Dean W, Reik W. Epigenetic reprogramming in mammals. Hum Mol Genet. 2005;14:R47-R58. doi: 10.1093/hmg/ddi114.
-
(2005)
Hum Mol Genet
, vol.14
, pp. R47-R58
-
-
Morgan, H.D.1
Santos, F.2
Green, K.3
Dean, W.4
Reik, W.5
-
13
-
-
33847037497
-
Noncoding RNAs and gene silencing
-
Zaratiegui M, Irvine DV, Martienssen RA. Noncoding RNAs and gene silencing. Cell. 2007;128:763-776. doi: 10.1016/j.cell.2007.02.016.
-
(2007)
Cell
, vol.128
, pp. 763-776
-
-
Zaratiegui, M.1
Irvine, D.V.2
Martienssen, R.A.3
-
14
-
-
0033569641
-
Epigenetics: Regulation through repression
-
Wolffe AP, Matzke MA. Epigenetics: regulation through repression. Science. 1999;286:481-486.
-
(1999)
Science
, vol.286
, pp. 481-486
-
-
Wolffe, A.P.1
Matzke, M.A.2
-
15
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A. DNA methylation patterns and epigenetic memory. Genes Dev. 2002;16:6-21. doi: 10.1101/gad.947102.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
16
-
-
84892763878
-
Reversing DNA methylation: Mechanisms, genomics, and biological functions
-
Wu H, Zhang Y. Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell. 2014;156:45-68. doi: 10.1016/j. cell.2013.12.019.
-
(2014)
Cell
, vol.156
, pp. 45-68
-
-
Wu, H.1
Zhang, Y.2
-
17
-
-
79951774325
-
DNA methylation of genes in adipose tissue
-
Pinnick KE, Karpe F. DNA methylation of genes in adipose tissue. Proc Nutr Soc. 2011;70:57-63. doi: 10.1017/S0029665110004015.
-
(2011)
Proc Nutr Soc
, vol.70
, pp. 57-63
-
-
Pinnick, K.E.1
Karpe, F.2
-
18
-
-
84874194072
-
DNA methylation: Roles in mammalian development
-
Smith ZD, Meissner A. DNA methylation: roles in mammalian development. Nat Rev Genet. 2013;14:204-220. doi: 10.1038/nrg3354.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 204-220
-
-
Smith, Z.D.1
Meissner, A.2
-
19
-
-
77956095231
-
Active DNA demethylation: Many roads lead to Rome
-
Wu SC, Zhang Y. Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol. 2010;11:607-620. doi: 10.1038/nrm2950.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 607-620
-
-
Wu, S.C.1
Zhang, Y.2
-
20
-
-
77249137168
-
Principles and challenges of genomewide DNA methylation analysis
-
Laird PW. Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet. 2010;11:191-203. doi: 10.1038/nrg2732.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 191-203
-
-
Laird, P.W.1
-
21
-
-
47649085663
-
Epigenetic control of 11 beta-hydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension
-
Friso S, Pizzolo F, Choi SW, Guarini P, Castagna A, Ravagnani V, Carletto A, Pattini P, Corrocher R, Olivieri O. Epigenetic control of 11 beta-hydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension. Atherosclerosis. 2008;199:323-327. doi: 10.1016/j. atherosclerosis.2007.11.029.
-
(2008)
Atherosclerosis
, vol.199
, pp. 323-327
-
-
Friso, S.1
Pizzolo, F.2
Choi, S.W.3
Guarini, P.4
Castagna, A.5
Ravagnani, V.6
Carletto, A.7
Pattini, P.8
Corrocher, R.9
Olivieri, O.10
-
23
-
-
4644231710
-
DNA methylation is a nonredundant repressor of the Th2 effector program
-
Makar KW, Wilson CB. DNA methylation is a nonredundant repressor of the Th2 effector program. J Immunol. 2004;173:4402-4406.
-
(2004)
J Immunol
, vol.173
, pp. 4402-4406
-
-
Makar, K.W.1
Wilson, C.B.2
-
24
-
-
0035282903
-
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition
-
Chen Z, Karaplis AC, Ackerman SL, et al. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Hum Mol Genet. 2001;10:433-443.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 433-443
-
-
Chen, Z.1
Karaplis, A.C.2
Ackerman, S.L.3
-
25
-
-
3142672297
-
DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein e
-
Lund G, Andersson L, Lauria M, Lindholm M, Fraga MF, Villar-Garea A, Ballestar E, Esteller M, Zaina S. DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E. J Biol Chem. 2004;279:29147-29154. doi: 10.1074/jbc.M403618200.
-
(2004)
J Biol Chem
, vol.279
, pp. 29147-29154
-
-
Lund, G.1
Andersson, L.2
Lauria, M.3
Lindholm, M.4
Fraga, M.F.5
Villar-Garea, A.6
Ballestar, E.7
Esteller, M.8
Zaina, S.9
-
26
-
-
77649197044
-
Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure
-
Movassagh M, Choy MK, Goddard M, Bennett MR, Down TA, Foo RS. Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure. PLoS One. 2010;5:e8564. doi: 10.1371/journal.pone.0008564.
-
(2010)
PLoS One
, vol.5
, pp. e8564
-
-
Movassagh, M.1
Choy, M.K.2
Goddard, M.3
Bennett, M.R.4
Down, T.A.5
Foo, R.S.6
-
27
-
-
77958489643
-
Ischemic heart disease and stroke in relation to blood DNA methylation
-
Baccarelli A, Wright R, Bollati V, Litonjua A, Zanobetti A, Tarantini L, Sparrow D, Vokonas P, Schwartz J. Ischemic heart disease and stroke in relation to blood DNA methylation. Epidemiology. 2010;21:819-828. doi: 10.1097/EDE.0b013e3181f20457.
-
(2010)
Epidemiology
, vol.21
, pp. 819-828
-
-
Baccarelli, A.1
Wright, R.2
Bollati, V.3
Litonjua, A.4
Zanobetti, A.5
Tarantini, L.6
Sparrow, D.7
Vokonas, P.8
Schwartz, J.9
-
28
-
-
77953825565
-
DNA methylation as a biomarker for cardiovascular disease risk
-
Kim M, Long TI, Arakawa K, Wang R, Yu MC, Laird PW. DNA methylation as a biomarker for cardiovascular disease risk. PLoS One. 2010;5:e9692. doi: 10.1371/journal.pone.0009692.
-
(2010)
PLoS One
, vol.5
, pp. e9692
-
-
Kim, M.1
Long, T.I.2
Arakawa, K.3
Wang, R.4
Yu, M.C.5
Laird, P.W.6
-
29
-
-
79951903268
-
Genome-wide DNA methylation in human heart failure
-
Movassagh M, Vujic A, Foo R. Genome-wide DNA methylation in human heart failure. Epigenomics. 2011;3:103-109. doi: 10.2217/epi.10.70.
-
(2011)
Epigenomics
, vol.3
, pp. 103-109
-
-
Movassagh, M.1
Vujic, A.2
Foo, R.3
-
30
-
-
84858636393
-
Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction
-
PROSPER Group
-
Talens RP, Jukema JW, Trompet S, Kremer D, Westendorp RG, Lumey LH, Sattar N, Putter H, Slagboom PE, Heijmans BT; PROSPER Group. Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction. Int J Epidemiol. 2012;41:106-115. doi: 10.1093/ije/dyr153.
-
(2012)
Int J Epidemiol
, vol.41
, pp. 106-115
-
-
Talens, R.P.1
Jukema, J.W.2
Trompet, S.3
Kremer, D.4
Westendorp, R.G.5
Lumey, L.H.6
Sattar, N.7
Putter, H.8
Slagboom, P.E.9
Heijmans, B.T.10
-
31
-
-
84862127099
-
Environmental exposures, epigenetics and cardiovascular disease
-
Baccarelli A, Ghosh S. Environmental exposures, epigenetics and cardiovascular disease. Curr Opin Clin Nutr Metab Care. 2012;15:323-329. doi: 10.1097/MCO.0b013e328354bf5c.
-
(2012)
Curr Opin Clin Nutr Metab Care
, vol.15
, pp. 323-329
-
-
Baccarelli, A.1
Ghosh, S.2
-
32
-
-
4444382796
-
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study
-
INTERHEART Study Investigators
-
Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, McQueen M, Budaj A, Pais P, Varigos J, Lisheng L; INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004;364:937-952. doi: 10.1016/S0140-6736(04)17018-9.
-
(2004)
Lancet
, vol.364
, pp. 937-952
-
-
Yusuf, S.1
Hawken, S.2
Ounpuu, S.3
Dans, T.4
Avezum, A.5
Lanas, F.6
McQueen, M.7
Budaj, A.8
Pais, P.9
Varigos, J.10
Lisheng, L.11
-
33
-
-
68849098348
-
Healthy living is the best revenge: Findings from the European Prospective Investigation into Cancer and Nutrition-Potsdam study
-
Ford ES, Bergmann MM, Kröger J, Schienkiewitz A, Weikert C, Boeing H. Healthy living is the best revenge: findings from the European Prospective Investigation Into Cancer and Nutrition-Potsdam study. Arch Intern Med. 2009;169:1355-1362. doi: 10.1001/archinternmed.2009.237.
-
(2009)
Arch Intern Med
, vol.169
, pp. 1355-1362
-
-
Ford, E.S.1
Bergmann, M.M.2
Kröger, J.3
Schienkiewitz, A.4
Weikert, C.5
Boeing, H.6
-
34
-
-
0027376801
-
Socioeconomic factors and cardiovascular disease: A review of the literature
-
Kaplan GA, Keil JE. Socioeconomic factors and cardiovascular disease: a review of the literature. Circulation. 1993;88:1973-1998.
-
(1993)
Circulation
, vol.88
, pp. 1973-1998
-
-
Kaplan, G.A.1
Keil, J.E.2
-
35
-
-
53049106445
-
Combined impact of lifestyle factors on mortality: Prospective cohort study in US women
-
van Dam RM, Li T, Spiegelman D, Franco OH, Hu FB. Combined impact of lifestyle factors on mortality: prospective cohort study in US women. BMJ. 2008;337:a1440.
-
(2008)
BMJ
, vol.337
, pp. a1440
-
-
Van Dam, R.M.1
Li, T.2
Spiegelman, D.3
Franco, O.H.4
Hu, F.B.5
-
36
-
-
58149497235
-
Developmental and epigenetic pathways to obesity: An evolutionary-developmental perspective
-
Gluckman PD, Hanson MA. Developmental and epigenetic pathways to obesity: an evolutionary-developmental perspective. Int J Obes (Lond). 2008;32(suppl 7):S62-S71. doi: 10.1038/ijo.2008.240.
-
(2008)
Int J Obes (Lond)
, vol.32
, pp. S62-S71
-
-
Gluckman, P.D.1
Hanson, M.A.2
-
37
-
-
84866423735
-
Environmental epigenetics: A role in endocrine disease
-
Fleisch AF, Wright RO, Baccarelli AA. Environmental epigenetics: a role in endocrine disease J Mol Endocrinol. 2012;49:R61-R67. doi: 10.1530/JME-12-0066.
-
(2012)
J Mol Endocrinol
, vol.49
, pp. R61-R67
-
-
Fleisch, A.F.1
Wright, R.O.2
Baccarelli, A.A.3
-
38
-
-
33645633542
-
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
-
Dolinoy DC, Weidman JR, Waterland RA, Jirtle RL. Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect. 2006;114:567-572.
-
(2006)
Environ Health Perspect
, vol.114
, pp. 567-572
-
-
Dolinoy, D.C.1
Weidman, J.R.2
Waterland, R.A.3
Jirtle, R.L.4
-
39
-
-
37649011327
-
DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status
-
Sinclair KD, Allegrucci C, Singh R, Gardner DS, Sebastian S, Bispham J, Thurston A, Huntley JF, Rees WD, Maloney CA, Lea RG, Craigon J, McEvoy TG, Young LE. DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. Proc Natl Acad Sci USA. 2007;104:19351-19356. doi: 10.1073/pnas.0707258104.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19351-19356
-
-
Sinclair, K.D.1
Allegrucci, C.2
Singh, R.3
Gardner, D.S.4
Sebastian, S.5
Bispham, J.6
Thurston, A.7
Huntley, J.F.8
Rees, W.D.9
Maloney, C.A.10
Lea, R.G.11
Craigon, J.12
McEvoy, T.G.13
Young, L.E.14
-
40
-
-
50049108528
-
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring
-
Lillycrop KA, Phillips ES, Torrens C, Hanson MA, Jackson AA, Burdge GC. Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr. 2008;100:278-282. doi: 10.1017/S0007114507894438.
-
(2008)
Br J Nutr
, vol.100
, pp. 278-282
-
-
Lillycrop, K.A.1
Phillips, E.S.2
Torrens, C.3
Hanson, M.A.4
Jackson, A.A.5
Burdge, G.C.6
-
41
-
-
34247514180
-
Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications
-
Lillycrop KA, Slater-Jefferies JL, Hanson MA, Godfrey KM, Jackson AA, Burdge GC. Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications. Br J Nutr. 2007;97:1064-1073. doi: 10.1017/S000711450769196X.
-
(2007)
Br J Nutr
, vol.97
, pp. 1064-1073
-
-
Lillycrop, K.A.1
Slater-Jefferies, J.L.2
Hanson, M.A.3
Godfrey, K.M.4
Jackson, A.A.5
Burdge, G.C.6
-
42
-
-
77957258099
-
Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes
-
Vucetic Z, Kimmel J, Totoki K, Hollenbeck E, Reyes TM. Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes. Endocrinology. 2010;151:4756-4764. doi: 10.1210/en.2010-0505.
-
(2010)
Endocrinology
, vol.151
, pp. 4756-4764
-
-
Vucetic, Z.1
Kimmel, J.2
Totoki, K.3
Hollenbeck, E.4
Reyes, T.M.5
-
43
-
-
37049020951
-
Cohort profile: The Dutch Hunger Winter families study
-
Lumey LH, Stein AD, Kahn HS, van der Pal-de Bruin KM, Blauw GJ, Zybert PA, Susser ES. Cohort profile: the Dutch Hunger Winter families study. Int J Epidemiol. 2007;36:1196-1204. doi: 10.1093/ije/dym126.
-
(2007)
Int J Epidemiol
, vol.36
, pp. 1196-1204
-
-
Lumey, L.H.1
Stein, A.D.2
Kahn, H.S.3
Van Der Pal-De Bruin, K.M.4
Blauw, G.J.5
Zybert, P.A.6
Susser, E.S.7
-
44
-
-
21944442058
-
Prenatal exposure to the Dutch famine and disease in later life: An overview
-
Painter RC, Roseboom TJ, Bleker OP. Prenatal exposure to the Dutch famine and disease in later life: an overview. Reprod Toxicol. 2005;20:345-352. doi: 10.1016/j.reprotox.2005.04.005.
-
(2005)
Reprod Toxicol
, vol.20
, pp. 345-352
-
-
Painter, R.C.1
Roseboom, T.J.2
Bleker, O.P.3
-
45
-
-
33746911576
-
The Dutch famine and its long-term consequences for adult health
-
Roseboom T, de Rooij S, Painter R. The Dutch famine and its long-term consequences for adult health. Early Hum Dev. 2006;82:485-491. doi: 10.1016/j.earlhumdev.2006.07.001.
-
(2006)
Early Hum Dev
, vol.82
, pp. 485-491
-
-
Roseboom, T.1
De Rooij, S.2
Painter, R.3
-
46
-
-
55949137722
-
Persistent epigenetic differences associated with prenatal exposure to famine in humans
-
Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, Slagboom PE, Lumey LH. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA. 2008;105:17046-17049. doi: 10.1073/pnas.0806560105.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17046-17049
-
-
Heijmans, B.T.1
Tobi, E.W.2
Stein, A.D.3
Putter, H.4
Blauw, G.J.5
Susser, E.S.6
Slagboom, P.E.7
Lumey, L.H.8
-
47
-
-
70349999407
-
DNA methylation differences after exposure to prenatal famine are common and timing-and sex-specific
-
Tobi EW, Lumey LH, Talens RP, Kremer D, Putter H, Stein AD, Slagboom PE, Heijmans BT. DNA methylation differences after exposure to prenatal famine are common and timing-and sex-specific. Hum Mol Genet. 2009;18:4046-4053. doi: 10.1093/hmg/ddp353.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4046-4053
-
-
Tobi, E.W.1
Lumey, L.H.2
Talens, R.P.3
Kremer, D.4
Putter, H.5
Stein, A.D.6
Slagboom, P.E.7
Heijmans, B.T.8
-
48
-
-
79960150663
-
Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancy
-
Hoyo C, Murtha AP, Schildkraut JM, Jirtle RL, Demark-Wahnefried W, Forman MR, Iversen ES, Kurtzberg J, Overcash F, Huang Z, Murphy SK. Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancy. Epigenetics. 2011;6:928-936.
-
(2011)
Epigenetics
, vol.6
, pp. 928-936
-
-
Hoyo, C.1
Murtha, A.P.2
Schildkraut, J.M.3
Jirtle, R.L.4
Demark-Wahnefried, W.5
Forman, M.R.6
Iversen, E.S.7
Kurtzberg, J.8
Overcash, F.9
Huang, Z.10
Murphy, S.K.11
-
49
-
-
77957333258
-
Induction of epigenetic alterations by dietary and other environmental factors
-
Mathers JC, Strathdee G, Relton CL. Induction of epigenetic alterations by dietary and other environmental factors. Adv Genet. 2010;71:3-39. doi: 10.1016/B978-0-12-380864-6.00001-8.
-
(2010)
Adv Genet
, vol.71
, pp. 3-39
-
-
Mathers, J.C.1
Strathdee, G.2
Relton, C.L.3
-
50
-
-
70649097099
-
Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child
-
Steegers-Theunissen RP, Obermann-Borst SA, Kremer D, Lindemans J, Siebel C, Steegers EA, Slagboom PE, Heijmans BT. Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child. PLoS One. 2009;4:e7845. doi: 10.1371/journal.pone.0007845.
-
(2009)
PLoS One
, vol.4
, pp. e7845
-
-
Steegers-Theunissen, R.P.1
Obermann-Borst, S.A.2
Kremer, D.3
Lindemans, J.4
Siebel, C.5
Steegers, E.A.6
Slagboom, P.E.7
Heijmans, B.T.8
-
51
-
-
79953798143
-
Relationship of folate, vitamin B12 and methylation of insulin-like growth factor-II in maternal and cord blood
-
Ba Y, Yu H, Liu F, Geng X, Zhu C, Zhu Q, Zheng T, Ma S, Wang G, Li Z, Zhang Y. Relationship of folate, vitamin B12 and methylation of insulin-like growth factor-II in maternal and cord blood. Eur J Clin Nutr. 2011;65:480-485. doi: 10.1038/ejcn.2010.294.
-
(2011)
Eur J Clin Nutr
, vol.65
, pp. 480-485
-
-
Ba, Y.1
Yu, H.2
Liu, F.3
Geng, X.4
Zhu, C.5
Zhu, Q.6
Zheng, T.7
Ma, S.8
Wang, G.9
Li, Z.10
Zhang, Y.11
-
52
-
-
0345275879
-
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
-
Fang MZ, Wang Y, Ai N, Hou Z, Sun Y, Lu H, Welsh W, Yang CS. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res. 2003;63:7563-7570.
-
(2003)
Cancer Res
, vol.63
, pp. 7563-7570
-
-
Fang, M.Z.1
Wang, Y.2
Ai, N.3
Hou, Z.4
Sun, Y.5
Lu, H.6
Welsh, W.7
Yang, C.S.8
-
53
-
-
84860006823
-
Dietary and lifestyle factors of DNA methylation
-
Lim U, Song MA. Dietary and lifestyle factors of DNA methylation. Methods Mol Biol. 2012;863:359-376. doi: 10.1007/978-1-61779-612-8-23.
-
(2012)
Methods Mol Biol
, vol.863
, pp. 359-376
-
-
Lim, U.1
Song, M.A.2
-
54
-
-
79958186419
-
Dietary patterns are associated with levels of global genomic DNA methylation in a cancer-free population
-
Zhang FF, Morabia A, Carroll J, Gonzalez K, Fulda K, Kaur M, Vishwanatha JK, Santella RM, Cardarelli R. Dietary patterns are associated with levels of global genomic DNA methylation in a cancer-free population. J Nutr. 2011;141:1165-1171. doi: 10.3945/jn.110.134536.
-
(2011)
J Nutr
, vol.141
, pp. 1165-1171
-
-
Zhang, F.F.1
Morabia, A.2
Carroll, J.3
Gonzalez, K.4
Fulda, K.5
Kaur, M.6
Vishwanatha, J.K.7
Santella, R.M.8
Cardarelli, R.9
-
55
-
-
69249132169
-
Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation
-
Breton CV, Byun HM, Wenten M, Pan F, Yang A, Gilliland FD. Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. Am J Respir Crit Care Med. 2009;180:462-467. doi: 10.1164/rccm.200901-0135OC.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 462-467
-
-
Breton, C.V.1
Byun, H.M.2
Wenten, M.3
Pan, F.4
Yang, A.5
Gilliland, F.D.6
-
56
-
-
79953706343
-
Tobacco-smokingrelated differential DNA methylation: 27K discovery and replication
-
Breitling LP, Yang R, Korn B, Burwinkel B, Brenner H. Tobacco-smokingrelated differential DNA methylation: 27K discovery and replication. Am J Hum Genet. 2011;88:450-457. doi: 10.1016/j.ajhg.2011.03.003.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 450-457
-
-
Breitling, L.P.1
Yang, R.2
Korn, B.3
Burwinkel, B.4
Brenner, H.5
-
57
-
-
33748495552
-
Protease-activated receptors in cardiovascular diseases
-
Leger AJ, Covic L, Kuliopulos A. Protease-activated receptors in cardiovascular diseases. Circulation. 2006;114:1070-1077. doi: 10.1161/CIRCULATIONAHA.105.574830.
-
(2006)
Circulation
, vol.114
, pp. 1070-1077
-
-
Leger, A.J.1
Covic, L.2
Kuliopulos, A.3
-
58
-
-
84867251622
-
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy
-
Joubert BR, Håberg SE, Nilsen RM, et al. 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ Health Perspect. 2012;120:1425-1431. doi: 10.1289/ehp.1205412.
-
(2012)
Environ Health Perspect
, vol.120
, pp. 1425-1431
-
-
Joubert, B.R.1
Håberg, S.E.2
Nilsen, R.M.3
-
59
-
-
84855839546
-
Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers
-
Monick MM, Beach SR, Plume J, Sears R, Gerrard M, Brody GH, Philibert RA. Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers. Am J Med Genet B Neuropsychiatr Genet. 2012;159B:141-151. doi: 10.1002/ajmg.b.32021.
-
(2012)
Am J Med Genet B Neuropsychiatr Genet
, vol.159 B
, pp. 141-151
-
-
Monick, M.M.1
Beach, S.R.2
Plume, J.3
Sears, R.4
Gerrard, M.5
Brody, G.H.6
Philibert, R.A.7
-
60
-
-
84935010496
-
Novel epigenetic changes unveiled by monozygotic twins discordant for smoking habits
-
Allione A, Marcon F, Fiorito G, Guarrera S, Siniscalchi E, Zijno A, Crebelli R, Matullo G. Novel epigenetic changes unveiled by monozygotic twins discordant for smoking habits. PLoS One. 2015;10:e0128265. doi: 10.1371/journal.pone.0128265.
-
(2015)
PLoS One
, vol.10
, pp. e0128265
-
-
Allione, A.1
Marcon, F.2
Fiorito, G.3
Guarrera, S.4
Siniscalchi, E.5
Zijno, A.6
Crebelli, R.7
Matullo, G.8
-
61
-
-
84863509978
-
Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome
-
Wan ES, Qiu W, Baccarelli A, Carey VJ, Bacherman H, Rennard SI, Agusti A, Anderson W, Lomas DA, Demeo DL. Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Hum Mol Genet. 2012;21:3073-3082. doi: 10.1093/hmg/dds135.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 3073-3082
-
-
Wan, E.S.1
Qiu, W.2
Baccarelli, A.3
Carey, V.J.4
Bacherman, H.5
Rennard, S.I.6
Agusti, A.7
Anderson, W.8
Lomas, D.A.9
Demeo, D.L.10
-
62
-
-
84893387036
-
F2RL3 methylation as a biomarker of current and lifetime smoking exposures
-
Zhang Y, Yang R, Burwinkel B, Breitling LP, Brenner H. F2RL3 methylation as a biomarker of current and lifetime smoking exposures. Environ Health Perspect. 2014;122:131-137. doi: 10.1289/ehp.1306937.
-
(2014)
Environ Health Perspect
, vol.122
, pp. 131-137
-
-
Zhang, Y.1
Yang, R.2
Burwinkel, B.3
Breitling, L.P.4
Brenner, H.5
-
64
-
-
0025098083
-
Decline in the risk of myocardial infarction among women who stop smoking
-
Rosenberg L, Palmer JR, Shapiro S. Decline in the risk of myocardial infarction among women who stop smoking. N Engl J Med. 1990;322:213-217. doi: 10.1056/NEJM199001253220401.
-
(1990)
N Engl J Med
, vol.322
, pp. 213-217
-
-
Rosenberg, L.1
Palmer, J.R.2
Shapiro, S.3
-
65
-
-
0027315444
-
Mortality in relation to smoking history: 13 years' follow-up of 68,000 Norwegian men and women 35-49 years
-
Tverdal A, Thelle D, Stensvold I, Leren P, Bjartveit K. Mortality in relation to smoking history: 13 years' follow-up of 68,000 Norwegian men and women 35-49 years. J Clin Epidemiol. 1993;46:475-487.
-
(1993)
J Clin Epidemiol
, vol.46
, pp. 475-487
-
-
Tverdal, A.1
Thelle, D.2
Stensvold, I.3
Leren, P.4
Bjartveit, K.5
-
66
-
-
2642540057
-
Air pollution and cardiovascular disease: A statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association
-
Expert Panel on Population and Prevention Science of the American Heart Association
-
Brook RD, Franklin B, Cascio W, Hong Y, Howard G, Lipsett M, Luepker R, Mittleman M, Samet J, Smith SC Jr, Tager I; Expert Panel on Population and Prevention Science of the American Heart Association. Air pollution and cardiovascular disease: a statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association. Circulation. 2004;109:2655-2671. doi: 10.1161/01. CIR.0000128587.30041.C8.
-
(2004)
Circulation
, vol.109
, pp. 2655-2671
-
-
Brook, R.D.1
Franklin, B.2
Cascio, W.3
Hong, Y.4
Howard, G.5
Lipsett, M.6
Luepker, R.7
Mittleman, M.8
Samet, J.9
Smith, S.C.10
Tager, I.11
-
67
-
-
77953229216
-
Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association
-
American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Council on Nutrition, Physical Activity and Metabolism
-
Brook RD, Rajagopalan S, Pope CA III, Brook JR, Bhatnagar A, Diez-Roux AV, Holguin F, Hong Y, Luepker RV, Mittleman MA, Peters A, Siscovick D, Smith SC Jr, Whitsel L, Kaufman JD; American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Council on Nutrition, Physical Activity and Metabolism. Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association. Circulation. 2010;121:2331-2378. doi: 10.1161/CIR.0b013e3181dbece1.
-
(2010)
Circulation
, vol.121
, pp. 2331-2378
-
-
Brook, R.D.1
Rajagopalan, S.2
Pope, C.A.3
Brook, J.R.4
Bhatnagar, A.5
Diez-Roux, A.V.6
Holguin, F.7
Hong, Y.8
Luepker, R.V.9
Mittleman, M.A.10
Peters, A.11
Siscovick, D.12
Smith, S.C.13
Whitsel, L.14
Kaufman, J.D.15
-
68
-
-
65249142729
-
Rapid DNA methylation changes after exposure to traffic particles
-
Baccarelli A, Wright RO, Bollati V, Tarantini L, Litonjua AA, Suh HH, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J. Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med. 2009;179:572-578. doi: 10.1164/rccm.200807-1097OC.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 572-578
-
-
Baccarelli, A.1
Wright, R.O.2
Bollati, V.3
Tarantini, L.4
Litonjua, A.A.5
Suh, H.H.6
Zanobetti, A.7
Sparrow, D.8
Vokonas, P.S.9
Schwartz, J.10
-
69
-
-
84857055272
-
Air pollution and markers of coagulation, inflammation, and endothelial function: Associations and epigene-environment interactions in an elderly cohort
-
Bind MA, Baccarelli A, Zanobetti A, Tarantini L, Suh H, Vokonas P, Schwartz J. Air pollution and markers of coagulation, inflammation, and endothelial function: associations and epigene-environment interactions in an elderly cohort. Epidemiology. 2012;23:332-340. doi: 10.1097/EDE.0b013e31824523f0.
-
(2012)
Epidemiology
, vol.23
, pp. 332-340
-
-
Bind, M.A.1
Baccarelli, A.2
Zanobetti, A.3
Tarantini, L.4
Suh, H.5
Vokonas, P.6
Schwartz, J.7
-
70
-
-
67749129297
-
Epigenetics and environmental chemicals
-
Baccarelli A, Bollati V. Epigenetics and environmental chemicals. Curr Opin Pediatr. 2009;21:243-251.
-
(2009)
Curr Opin Pediatr
, vol.21
, pp. 243-251
-
-
Baccarelli, A.1
Bollati, V.2
-
71
-
-
84899152478
-
Air pollution and genespecific methylation in the Normative Aging Study: Association, effect modification, and mediation analysis
-
Bind MA, Lepeule J, Zanobetti A, Gasparrini A, Baccarelli A, Coull BA, Tarantini L, Vokonas PS, Koutrakis P, Schwartz J. Air pollution and genespecific methylation in the Normative Aging Study: association, effect modification, and mediation analysis. Epigenetics. 2014;9:448-458. doi: 10.4161/epi.27584.
-
(2014)
Epigenetics
, vol.9
, pp. 448-458
-
-
Bind, M.A.1
Lepeule, J.2
Zanobetti, A.3
Gasparrini, A.4
Baccarelli, A.5
Coull, B.A.6
Tarantini, L.7
Vokonas, P.S.8
Koutrakis, P.9
Schwartz, J.10
-
72
-
-
60749124259
-
Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation
-
Tarantini L, Bonzini M, Apostoli P, Pegoraro V, Bollati V, Marinelli B, Cantone L, Rizzo G, Hou L, Schwartz J, Bertazzi PA, Baccarelli A. Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation. Environ Health Perspect. 2009;117:217-222. doi: 10.1289/ehp.11898.
-
(2009)
Environ Health Perspect
, vol.117
, pp. 217-222
-
-
Tarantini, L.1
Bonzini, M.2
Apostoli, P.3
Pegoraro, V.4
Bollati, V.5
Marinelli, B.6
Cantone, L.7
Rizzo, G.8
Hou, L.9
Schwartz, J.10
Bertazzi, P.A.11
Baccarelli, A.12
-
73
-
-
60849100524
-
Decline in genomic DNA methylation through aging in a cohort of elderly subjects
-
Bollati V, Schwartz J, Wright R, Litonjua A, Tarantini L, Suh H, Sparrow D, Vokonas P, Baccarelli A. Decline in genomic DNA methylation through aging in a cohort of elderly subjects. Mech Ageing Dev. 2009;130:234-239. doi: 10.1016/j.mad.2008.12.003.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 234-239
-
-
Bollati, V.1
Schwartz, J.2
Wright, R.3
Litonjua, A.4
Tarantini, L.5
Suh, H.6
Sparrow, D.7
Vokonas, P.8
Baccarelli, A.9
-
74
-
-
84862979818
-
Distinct DNA methylomes of newborns and centenarians
-
Heyn H, Li N, Ferreira HJ, et al. Distinct DNA methylomes of newborns and centenarians. Proc Natl Acad Sci USA. 2012;109:10522-10527. doi: 10.1073/pnas.1120658109.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 10522-10527
-
-
Heyn, H.1
Li, N.2
Ferreira, H.J.3
-
75
-
-
0015885681
-
The 5-methylcytosine in DNA of rats. Tissue and age specificity and the changes induced by hydrocortisone and other agents
-
Vanyushin BF, Nemirovsky LE, Klimenko VV, Vasiliev VK, Belozersky AN. The 5-methylcytosine in DNA of rats. Tissue and age specificity and the changes induced by hydrocortisone and other agents. Gerontologia. 1973;19:138-152.
-
(1973)
Gerontologia
, vol.19
, pp. 138-152
-
-
Vanyushin, B.F.1
Nemirovsky, L.E.2
Klimenko, V.V.3
Vasiliev, V.K.4
Belozersky, A.N.5
-
77
-
-
45849127657
-
Intra-individual change over time in DNA methylation with familial clustering
-
Bjornsson HT, Sigurdsson MI, Fallin MD, et al. Intra-individual change over time in DNA methylation with familial clustering. JAMA. 2008;299:2877-2883. doi: 10.1001/jama.299.24.2877.
-
(2008)
JAMA
, vol.299
, pp. 2877-2883
-
-
Bjornsson, H.T.1
Sigurdsson, M.I.2
Fallin, M.D.3
-
78
-
-
84866868744
-
Aging effects on DNA methylation modules in human brain and blood tissue
-
Horvath S, Zhang Y, Langfelder P, Kahn RS, Boks MP, van Eijk K, van den Berg LH, Ophoff RA. Aging effects on DNA methylation modules in human brain and blood tissue. Genome Biol. 2012;13:R97. doi: 10.1186/gb-2012-13-10-r97.
-
(2012)
Genome Biol
, vol.13
, pp. R97
-
-
Horvath, S.1
Zhang, Y.2
Langfelder, P.3
Kahn, R.S.4
Boks, M.P.5
Van Eijk, K.6
Van Den Berg, L.H.7
Ophoff, R.A.8
-
79
-
-
79952202597
-
Epigenetic regulation of aging
-
Rodríguez-Rodero S, Fernández-Morera JL, Fernandez AF, Menéndez-Torre E, Fraga MF. Epigenetic regulation of aging. Discov Med. 2010;10:225-233.
-
(2010)
Discov Med
, vol.10
, pp. 225-233
-
-
Rodríguez-Rodero, S.1
Fernández-Morera, J.L.2
Fernandez, A.F.3
Menéndez-Torre, E.4
Fraga, M.F.5
-
80
-
-
77950650405
-
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer
-
Teschendorff AE, Menon U, Gentry-Maharaj A, et al. Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res. 2010;20:440-446. doi: 10.1101/gr.103606.109.
-
(2010)
Genome Res
, vol.20
, pp. 440-446
-
-
Teschendorff, A.E.1
Menon, U.2
Gentry-Maharaj, A.3
-
81
-
-
84860572791
-
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
-
MuTHER Consortium
-
Bell JT, Tsai PC, Yang TP, et al; MuTHER Consortium. Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet. 2012;8:e1002629. doi: 10.1371/journal.pgen.1002629.
-
(2012)
PLoS Genet
, vol.8
, pp. e1002629
-
-
Bell, J.T.1
Tsai, P.C.2
Yang, T.P.3
-
82
-
-
70149099610
-
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
-
Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet. 2009;5:e1000602. doi: 10.1371/journal.pgen.1000602.
-
(2009)
PLoS Genet
, vol.5
, pp. e1000602
-
-
Christensen, B.C.1
Houseman, E.A.2
Marsit, C.J.3
Zheng, S.4
Wrensch, M.R.5
Wiemels, J.L.6
Nelson, H.H.7
Karagas, M.R.8
Padbury, J.F.9
Bueno, R.10
Sugarbaker, D.J.11
Yeh, R.F.12
Wiencke, J.K.13
Kelsey, K.T.14
-
83
-
-
77950657253
-
Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
-
Rakyan VK, Down TA, Maslau S, Andrew T, Yang TP, Beyan H, Whittaker P, McCann OT, Finer S, Valdes AM, Leslie RD, Deloukas P, Spector TD. Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains. Genome Res. 2010;20:434-439. doi: 10.1101/gr.103101.109.
-
(2010)
Genome Res
, vol.20
, pp. 434-439
-
-
Rakyan, V.K.1
Down, T.A.2
Maslau, S.3
Andrew, T.4
Yang, T.P.5
Beyan, H.6
Whittaker, P.7
McCann, O.T.8
Finer, S.9
Valdes, A.M.10
Leslie, R.D.11
Deloukas, P.12
Spector, T.D.13
-
84
-
-
84886111619
-
DNA methylation age of human tissues and cell types
-
Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14:R115. doi: 10.1186/gb-2013-14-10-r115.
-
(2013)
Genome Biol
, vol.14
, pp. R115
-
-
Horvath, S.1
-
85
-
-
84908441328
-
Obesity accelerates epigenetic aging of human liver
-
Horvath S, Erhart W, Brosch M, et al. Obesity accelerates epigenetic aging of human liver. Proc Natl Acad Sci USA. 2014;111:15538-15543. doi: 10.1073/pnas.1412759111.
-
(2014)
Proc Natl Acad Sci USA.
, vol.111
, pp. 15538-15543
-
-
Horvath, S.1
Erhart, W.2
Brosch, M.3
-
86
-
-
84926674860
-
DNA methylation age of blood predicts all-cause mortality in later life
-
Marioni RE, Shah S, McRae AF, et al. DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol. 2015;16:25. doi: 10.1186/s13059-015-0584-6.
-
(2015)
Genome Biol
, vol.16
, pp. 25
-
-
Marioni, R.E.1
Shah, S.2
McRae, A.F.3
-
87
-
-
84863469546
-
The role of longitudinal cohort studies in epigenetic epidemiology: Challenges and opportunities
-
Ng JW, Barrett LM, Wong A, Kuh D, Smith GD, Relton CL. The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities. Genome Biol. 2012;13:246. doi: 10.1186/gb-2012-13-6-246.
-
(2012)
Genome Biol
, vol.13
, pp. 246
-
-
Ng, J.W.1
Barrett, L.M.2
Wong, A.3
Kuh, D.4
Smith, G.D.5
Relton, C.L.6
-
88
-
-
79960556965
-
Epigenome-wide association studies for common human diseases
-
Rakyan VK, Down TA, Balding DJ, Beck S. Epigenome-wide association studies for common human diseases. Nat Rev Genet. 2011;12:529-541. doi: 10.1038/nrg3000.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 529-541
-
-
Rakyan, V.K.1
Down, T.A.2
Balding, D.J.3
Beck, S.4
-
89
-
-
84863337808
-
Is epidemiology ready for epigenetics
-
Relton CL, Davey Smith G. Is epidemiology ready for epigenetics Int J Epidemiol. 2012;41:5-9. doi: 10.1093/ije/dys006.
-
(2012)
Int J Epidemiol
, vol.41
, pp. 5-9
-
-
Relton, C.L.1
Davey Smith, G.2
-
90
-
-
84943792919
-
Adiposity is associated with DNA methylation profile in adipose tissue
-
Agha G, Houseman EA, Kelsey KT, Eaton CB, Buka SL, Loucks EB. Adiposity is associated with DNA methylation profile in adipose tissue. Int J Epidemiol. 2015;44:1277-1287. doi: 10.1093/ije/dyu236.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 1277-1287
-
-
Agha, G.1
Houseman, E.A.2
Kelsey, K.T.3
Eaton, C.B.4
Buka, S.L.5
Loucks, E.B.6
-
91
-
-
75649087405
-
Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction
-
Bouchard L, Rabasa-Lhoret R, Faraj M, Lavoie ME, Mill J, Pérusse L, Vohl MC. Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction. Am J Clin Nutr. 2010;91:309-320. doi: 10.3945/ajcn.2009.28085.
-
(2010)
Am J Clin Nutr
, vol.91
, pp. 309-320
-
-
Bouchard, L.1
Rabasa-Lhoret, R.2
Faraj, M.3
Lavoie, M.E.4
Mill, J.5
Pérusse, L.6
Vohl, M.C.7
-
92
-
-
84921316380
-
DNA methylation and bodymass index: A genome-wide analysis
-
Dick KJ, Nelson CP, Tsaprouni L, et al. DNA methylation and bodymass index: a genome-wide analysis. Lancet. 2014;383:1990-1998. doi: 10.1016/S0140-6736(13)62674-4.
-
(2014)
Lancet
, vol.383
, pp. 1990-1998
-
-
Dick, K.J.1
Nelson, C.P.2
Tsaprouni, L.3
-
93
-
-
84898935560
-
Predicting DNA methylation level across human tissues
-
Ma B, Wilker EH, Willis-Owen SA, Byun HM, Wong KC, Motta V, Baccarelli AA, Schwartz J, Cookson WO, Khabbaz K, Mittleman MA, Moffatt MF, Liang L. Predicting DNA methylation level across human tissues. Nucleic Acids Res. 2014;42:3515-3528. doi: 10.1093/nar/gkt1380.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 3515-3528
-
-
Ma, B.1
Wilker, E.H.2
Willis-Owen, S.A.3
Byun, H.M.4
Wong, K.C.5
Motta, V.6
Baccarelli, A.A.7
Schwartz, J.8
Cookson, W.O.9
Khabbaz, K.10
Mittleman, M.A.11
Moffatt, M.F.12
Liang, L.13
-
94
-
-
82355180985
-
Distinct epigenomic features in end-stage failing human hearts
-
Movassagh M, Choy MK, Knowles DA, Cordeddu L, Haider S, Down T, Siggens L, Vujic A, Simeoni I, Penkett C, Goddard M, Lio P, Bennett MR, Foo RS. Distinct epigenomic features in end-stage failing human hearts. Circulation. 2011;124:2411-2422. doi: 10.1161/CIRCULATIONAHA.111.040071.
-
(2011)
Circulation
, vol.124
, pp. 2411-2422
-
-
Movassagh, M.1
Choy, M.K.2
Knowles, D.A.3
Cordeddu, L.4
Haider, S.5
Down, T.6
Siggens, L.7
Vujic, A.8
Simeoni, I.9
Penkett, C.10
Goddard, M.11
Lio, P.12
Bennett, M.R.13
Foo, R.S.14
-
95
-
-
84884592505
-
Review of processing and analysis methods for DNA methylation array data
-
Wilhelm-Benartzi CS, Koestler DC, Karagas MR, Flanagan JM, Christensen BC, Kelsey KT, Marsit CJ, Houseman EA, Brown R. Review of processing and analysis methods for DNA methylation array data. Br J Cancer. 2013;109:1394-1402. doi: 10.1038/bjc.2013.496.
-
(2013)
Br J Cancer
, vol.109
, pp. 1394-1402
-
-
Wilhelm-Benartzi, C.S.1
Koestler, D.C.2
Karagas, M.R.3
Flanagan, J.M.4
Christensen, B.C.5
Kelsey, K.T.6
Marsit, C.J.7
Houseman, E.A.8
Brown, R.9
-
96
-
-
84879678934
-
A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue
-
Rönn T, Volkov P, Davegårdh C, Dayeh T, Hall E, Olsson AH, Nilsson E, Tornberg A, Dekker Nitert M, Eriksson KF, Jones HA, Groop L, Ling C. A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue. PLoS Genet. 2013;9:e1003572. doi: 10.1371/journal.pgen.1003572.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003572
-
-
Rönn, T.1
Volkov, P.2
Davegårdh, C.3
Dayeh, T.4
Hall, E.5
Olsson, A.H.6
Nilsson, E.7
Tornberg, A.8
Dekker Nitert, M.9
Eriksson, K.F.10
Jones, H.A.11
Groop, L.12
Ling, C.13
-
97
-
-
0036081355
-
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
-
Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 2002;30:207-210.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 207-210
-
-
Edgar, R.1
Domrachev, M.2
Lash, A.E.3
-
98
-
-
84860637797
-
DNA methylation arrays as surrogate measures of cell mixture distribution
-
Houseman EA, Accomando WP, Koestler DC, Christensen BC, Marsit CJ, Nelson HH, Wiencke JK, Kelsey KT. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics. 2012;13:86. doi: 10.1186/1471-2105-13-86.
-
(2012)
BMC Bioinformatics
, vol.13
, pp. 86
-
-
Houseman, E.A.1
Accomando, W.P.2
Koestler, D.C.3
Christensen, B.C.4
Marsit, C.J.5
Nelson, H.H.6
Wiencke, J.K.7
Kelsey, K.T.8
-
99
-
-
78651226750
-
Global methylation profiles in DNA from different blood cell types
-
Wu HC, Delgado-Cruzata L, Flom JD, Kappil M, Ferris JS, Liao Y, Santella RM, Terry MB. Global methylation profiles in DNA from different blood cell types. Epigenetics. 2011;6:76-85. doi: 10.4161/epi.6.1.13391.
-
(2011)
Epigenetics
, vol.6
, pp. 76-85
-
-
Wu, H.C.1
Delgado-Cruzata, L.2
Flom, J.D.3
Kappil, M.4
Ferris, J.S.5
Liao, Y.6
Santella, R.M.7
Terry, M.B.8
-
100
-
-
84899103134
-
Correcting for cell-type composition bias in epigenome-wide association studies
-
Lowe R, Rakyan VK. Correcting for cell-type composition bias in epigenome-wide association studies. Genome Med. 2014;6:23. doi: 10.1186/gm540.
-
(2014)
Genome Med
, vol.6
, pp. 23
-
-
Lowe, R.1
Rakyan, V.K.2
-
101
-
-
84893192328
-
Accounting for cellular heterogeneity is critical in epigenome-wide association studies
-
Jaffe AE, Irizarry RA. Accounting for cellular heterogeneity is critical in epigenome-wide association studies. Genome Biol. 2014;15:R31. doi: 10.1186/gb-2014-15-2-r31.
-
(2014)
Genome Biol
, vol.15
, pp. R31
-
-
Jaffe, A.E.1
Irizarry, R.A.2
-
102
-
-
84884828422
-
Recommendations for the design and analysis of epigenome-wide association studies
-
Michels KB, Binder AM, Dedeurwaerder S, Epstein CB, Greally JM, Gut I, Houseman EA, Izzi B, Kelsey KT, Meissner A, Milosavljevic A, Siegmund KD, Bock C, Irizarry RA. Recommendations for the design and analysis of epigenome-wide association studies. Nat Methods. 2013;10:949-955. doi: 10.1038/nmeth.2632.
-
(2013)
Nat Methods
, vol.10
, pp. 949-955
-
-
Michels, K.B.1
Binder, A.M.2
Dedeurwaerder, S.3
Epstein, C.B.4
Greally, J.M.5
Gut, I.6
Houseman, E.A.7
Izzi, B.8
Kelsey, K.T.9
Meissner, A.10
Milosavljevic, A.11
Siegmund, K.D.12
Bock, C.13
Irizarry, R.A.14
-
103
-
-
84900824657
-
Reference-free cell mixture adjustments in analysis of DNA methylation data
-
Houseman EA, Molitor J, Marsit CJ. Reference-free cell mixture adjustments in analysis of DNA methylation data. Bioinformatics. 2014;30:1431-1439. doi: 10.1093/bioinformatics/btu029.
-
(2014)
Bioinformatics
, vol.30
, pp. 1431-1439
-
-
Houseman, E.A.1
Molitor, J.2
Marsit, C.J.3
-
104
-
-
84895540377
-
Epigenomewide association studies without the need for cell-type composition
-
Zou J, Lippert C, Heckerman D, Aryee M, Listgarten J. Epigenomewide association studies without the need for cell-type composition. Nat Methods. 2014;11:309-311. doi: 10.1038/nmeth.2815.
-
(2014)
Nat Methods
, vol.11
, pp. 309-311
-
-
Zou, J.1
Lippert, C.2
Heckerman, D.3
Aryee, M.4
Listgarten, J.5
-
105
-
-
84928712138
-
Genome-wide assays that identify and quantify modified cytosines in human disease studies
-
Ulahannan N, Greally JM. Genome-wide assays that identify and quantify modified cytosines in human disease studies. Epigenetics Chromatin. 2015;8:5. doi: 10.1186/1756-8935-8-5.
-
(2015)
Epigenetics Chromatin
, vol.8
, pp. 5
-
-
Ulahannan, N.1
Greally, J.M.2
-
106
-
-
84884922407
-
Report on the 2nd annual infinium humanmethylation 450 Array Workshop
-
15 April 2013 QMUL, London, UK
-
Lowe R, Morris T. Report on the 2nd Annual Infinium Humanmethylation450 Array Workshop: 15 April 2013 QMUL, London, UK. Epigenetics. 2013;8:1123-1124. doi: 10.4161/epi.26073.
-
(2013)
Epigenetics
, vol.8
, pp. 1123-1124
-
-
Lowe, R.1
Morris, T.2
-
107
-
-
0037109785
-
Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays
-
Balog RP, de Souza YE, Tang HM, DeMasellis GM, Gao B, Avila A, Gaban DJ, Mittelman D, Minna JD, Luebke KJ, Garner HR. Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays. Anal Biochem. 2002;309:301-310.
-
(2002)
Anal Biochem
, vol.309
, pp. 301-310
-
-
Balog, R.P.1
De Souza, Y.E.2
Tang, H.M.3
DeMasellis, G.M.4
Gao, B.5
Avila, A.6
Gaban, D.J.7
Mittelman, D.8
Minna, J.D.9
Luebke, K.J.10
Garner, H.R.11
-
108
-
-
18444364803
-
A microarray-based method for detecting methylated loci
-
Hatada I, Kato A, Morita S, Obata Y, Nagaoka K, Sakurada A, Sato M, Horii A, Tsujimoto A, Matsubara K. A microarray-based method for detecting methylated loci. J Hum Genet. 2002;47:448-451. doi: 10.1007/s100380200063.
-
(2002)
J Hum Genet
, vol.47
, pp. 448-451
-
-
Hatada, I.1
Kato, A.2
Morita, S.3
Obata, Y.4
Nagaoka, K.5
Sakurada, A.6
Sato, M.7
Horii, A.8
Tsujimoto, A.9
Matsubara, K.10
-
109
-
-
84856306090
-
Genome-wide DNA methylation profiling using Infinium® assay
-
Bibikova M, Le J, Barnes B, Saedinia-Melnyk S, Zhou L, Shen R, Gunderson KL. Genome-wide DNA methylation profiling using Infinium® assay. Epigenomics. 2009;1:177-200. doi: 10.2217/epi.09.14.
-
(2009)
Epigenomics
, vol.1
, pp. 177-200
-
-
Bibikova, M.1
Le Barnes J, B.2
Saedinia-Melnyk, S.3
Zhou, L.4
Shen, R.5
Gunderson, K.L.6
-
110
-
-
82455206314
-
Evaluation of the Infinium Methylation 450K technology
-
Dedeurwaerder S, Defrance M, Calonne E, Denis H, Sotiriou C, Fuks F. Evaluation of the Infinium Methylation 450K technology. Epigenomics. 2011;3:771-784. doi: 10.2217/epi.11.105.
-
(2011)
Epigenomics
, vol.3
, pp. 771-784
-
-
Dedeurwaerder, S.1
Defrance, M.2
Calonne, E.3
Denis, H.4
Sotiriou, C.5
Fuks, F.6
-
111
-
-
33845432928
-
Adjusting batch effects in microarray expression data using empirical Bayes methods
-
Johnson WE, Li C, Rabinovic A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics. 2007;8:118-127. doi: 10.1093/biostatistics/kxj037.
-
(2007)
Biostatistics
, vol.8
, pp. 118-127
-
-
Johnson, W.E.1
Li, C.2
Rabinovic, A.3
-
112
-
-
77951846108
-
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
-
Meng H, Joyce AR, Adkins DE, Basu P, Jia Y, Li G, Sengupta TK, Zedler BK, Murrelle EL, van den Oord EJ. A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling. BMC Bioinformatics. 2010;11:227. doi: 10.1186/1471-2105-11-227.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 227
-
-
Meng, H.1
Joyce, A.R.2
Adkins, D.E.3
Basu, P.4
Jia, Y.5
Li, G.6
Sengupta, T.K.7
Zedler, B.K.8
Murrelle, E.L.9
Van Den Oord, E.J.10
-
113
-
-
84876538609
-
Low-level processing of Illumina Infinium DNA Methylation BeadArrays
-
Triche TJ Jr, Weisenberger DJ, Van Den Berg D, Laird PW, Siegmund KD. Low-level processing of Illumina Infinium DNA Methylation BeadArrays. Nucleic Acids Res. 2013;41:e90. doi: 10.1093/nar/gkt090.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. e90
-
-
Triche, T.J.1
Weisenberger, D.J.2
Van Den Berg, D.3
Laird, P.W.4
Siegmund, K.D.5
-
114
-
-
84876806540
-
A data-driven approach to preprocessing Illumina 450K methylation array data
-
Pidsley R, Y Wong CC, Volta M, Lunnon K, Mill J, Schalkwyk LC. A data-driven approach to preprocessing Illumina 450K methylation array data. BMC Genomics. 2013;14:293. doi: 10.1186/1471-2164-14-293.
-
(2013)
BMC Genomics
, vol.14
, pp. 293
-
-
Pidsley, R.1
Wong, C.C.Y.2
Volta, M.3
Lunnon, K.4
Mill, J.5
Schalkwyk, L.C.6
-
115
-
-
84875737335
-
An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform
-
Marabita F, Almgren M, Lindholm ME, Ruhrmann S, Fagerström-Billai F, Jagodic M, Sundberg CJ, Ekström TJ, Teschendorff AE, Tegnér J, Gomez-Cabrero D. An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform. Epigenetics. 2013;8:333-346. doi: 10.4161/epi.24008.
-
(2013)
Epigenetics
, vol.8
, pp. 333-346
-
-
Marabita, F.1
Almgren, M.2
Lindholm, M.E.3
Ruhrmann, S.4
Fagerström-Billai, F.5
Jagodic, M.6
Sundberg, C.J.7
Ekström, T.J.8
Teschendorff, A.E.9
Tegnér, J.10
Gomez-Cabrero, D.11
-
116
-
-
84872564830
-
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
-
Teschendorff AE, Marabita F, Lechner M, Bartlett T, Tegner J, Gomez-Cabrero D, Beck S. A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data. Bioinformatics. 2013;29:189-196. doi: 10.1093/bioinformatics/bts680.
-
(2013)
Bioinformatics
, vol.29
, pp. 189-196
-
-
Teschendorff, A.E.1
Marabita, F.2
Lechner, M.3
Bartlett, T.4
Tegner, J.5
Gomez-Cabrero, D.6
Beck, S.7
-
117
-
-
84892564202
-
A systematic assessment of normalization approaches for the Infinium 450K methylation platform
-
Wu MC, Joubert BR, Kuan PF, Håberg SE, Nystad W, Peddada SD, London SJ. A systematic assessment of normalization approaches for the Infinium 450K methylation platform. Epigenetics. 2014;9:318-329. doi: 10.4161/epi.27119.
-
(2014)
Epigenetics
, vol.9
, pp. 318-329
-
-
Wu, M.C.1
Joubert, B.R.2
Kuan, P.F.3
Håberg, S.E.4
Nystad, W.5
Peddada, S.D.6
London, S.J.7
-
118
-
-
84876230269
-
The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium as a model of collaborative science
-
Psaty BM, Sitlani C. The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium as a model of collaborative science. Epidemiology. 2013;24:346-348. doi: 10.1097/EDE.0b013e31828b2cbb.
-
(2013)
Epidemiology
, vol.24
, pp. 346-348
-
-
Psaty, B.M.1
Sitlani, C.2
-
119
-
-
9644271335
-
Maternal experiences of racism and violence as predictors of preterm birth: Rationale and study design
-
Rich-Edwards J, Krieger N, Majzoub J, Zierler S, Lieberman E, Gillman M. Maternal experiences of racism and violence as predictors of preterm birth: rationale and study design. Paediatr Perinat Epidemiol. 2001;15(suppl 2):124-135.
-
(2001)
Paediatr Perinat Epidemiol
, vol.15
, pp. 124-135
-
-
Rich-Edwards, J.1
Krieger, N.2
Majzoub, J.3
Zierler, S.4
Lieberman, E.5
Gillman, M.6
-
120
-
-
84875577737
-
Cohort Profile: The 'children of the 90s'-The index offspring of the Avon Longitudinal Study of Parents and Children
-
Boyd A, Golding J, Macleod J, Lawlor DA, Fraser A, Henderson J, Molloy L, Ness A, Ring S, Davey Smith G. Cohort Profile: the 'children of the 90s'-the index offspring of the Avon Longitudinal Study of Parents and Children. Int J Epidemiol. 2013;42:111-127. doi: 10.1093/ije/dys064.
-
(2013)
Int J Epidemiol
, vol.42
, pp. 111-127
-
-
Boyd, A.1
Golding, J.2
MacLeod, J.3
Lawlor, D.A.4
Fraser, A.5
Henderson, J.6
Molloy, L.7
Ness, A.8
Ring, S.9
Davey Smith, G.10
-
121
-
-
78649506925
-
Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus
-
International Type 2 Diabetes 1q Consortium
-
Bell CG, Finer S, Lindgren CM, et al; International Type 2 Diabetes 1q Consortium. Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus. PLoS One. 2010;5:e14040. doi: 10.1371/journal. pone.0014040.
-
(2010)
PLoS One
, vol.5
, pp. e14040
-
-
Bell, C.G.1
Finer, S.2
Lindgren, C.M.3
-
122
-
-
77649204292
-
Genetic control of individual differences in gene-specific methylation in human brain
-
Zhang D, Cheng L, Badner JA, Chen C, Chen Q, Luo W, Craig DW, Redman M, Gershon ES, Liu C. Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet. 2010;86:411-419. doi: 10.1016/j.ajhg.2010.02.005.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 411-419
-
-
Zhang, D.1
Cheng, L.2
Badner, J.A.3
Chen, C.4
Chen, Q.5
Luo, W.6
Craig, D.W.7
Redman, M.8
Gershon, E.S.9
Liu, C.10
-
123
-
-
38949127024
-
Mendelian randomization: Can genetic epidemiology help redress the failures of observational epidemiology
-
Ebrahim S, Davey Smith G. Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology Hum Genet. 2008;123:15-33. doi: 10.1007/s00439-007-0448-6.
-
(2008)
Hum Genet
, vol.123
, pp. 15-33
-
-
Ebrahim, S.1
Davey Smith, G.2
-
124
-
-
84858648623
-
Two-step epigenetic Mendelian randomization: A strategy for establishing the causal role of epigenetic processes in pathways to disease
-
Relton CL, Davey Smith G. Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int J Epidemiol. 2012;41:161-176. doi: 10.1093/ije/dyr233.
-
(2012)
Int J Epidemiol
, vol.41
, pp. 161-176
-
-
Relton, C.L.1
Davey Smith, G.2
-
125
-
-
77952717253
-
Illustrating bias due to conditioning on a collider
-
Cole SR, Platt RW, Schisterman EF, Chu H, Westreich D, Richardson D, Poole C. Illustrating bias due to conditioning on a collider. Int J Epidemiol. 2010;39:417-420. doi: 10.1093/ije/dyp334.
-
(2010)
Int J Epidemiol
, vol.39
, pp. 417-420
-
-
Cole, S.R.1
Platt, R.W.2
Schisterman, E.F.3
Chu, H.4
Westreich, D.5
Richardson, D.6
Poole, C.7
-
126
-
-
41549104622
-
Alcohol intake and blood pressure: A systematic review implementing a Mendelian randomization approach
-
Chen L, Smith GD, Harbord RM, Lewis SJ. Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach. PLoS Med. 2008;5:e52. doi: 10.1371/journal.pmed.0050052.
-
(2008)
PLoS Med
, vol.5
, pp. e52
-
-
Chen, L.1
Smith, G.D.2
Harbord, R.M.3
Lewis, S.J.4
-
127
-
-
67649855154
-
Does greater adiposity increase blood pressure and hypertension risk: Mendelian randomization using the FTO/MC4R genotype
-
Timpson NJ, Harbord R, Davey Smith G, Zacho J, Tybjaerg-Hansen A, Nordestgaard BG. Does greater adiposity increase blood pressure and hypertension risk: Mendelian randomization using the FTO/MC4R genotype. Hypertension. 2009;54:84-90. doi: 10.1161/HYPERTENSIONAHA.109.130005.
-
(2009)
Hypertension
, vol.54
, pp. 84-90
-
-
Timpson, N.J.1
Harbord, R.2
Davey Smith, G.3
Zacho, J.4
Tybjaerg-Hansen, A.5
Nordestgaard, B.G.6
-
128
-
-
79952843139
-
Low-density lipoprotein cholesterol and the risk of cancer: A mendelian randomization study
-
Benn M, Tybjærg-Hansen A, Stender S, Frikke-Schmidt R, Nordestgaard BG. Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study. J Natl Cancer Inst. 2011;103:508-519. doi: 10.1093/jnci/djr008.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 508-519
-
-
Benn, M.1
Tybjærg-Hansen, A.2
Stender, S.3
Frikke-Schmidt, R.4
Nordestgaard, B.G.5
-
129
-
-
1542709218
-
Fibrinogen C-reactive protein and coronary heart disease: Does Mendelian randomization suggest the associations are non-causal
-
Davey Smith G, Harbord R, Ebrahim S. Fibrinogen, C-reactive protein and coronary heart disease: does Mendelian randomization suggest the associations are non-causal QJM. 2004;97:163-166.
-
(2004)
QJM
, vol.97
, pp. 163-166
-
-
Davey Smith, G.1
Harbord, R.2
Ebrahim, S.3
-
130
-
-
84888788432
-
The causal effect of red blood cell folate on genome-wide methylation in cord blood: A Mendelian randomization approach
-
Binder AM, Michels KB. The causal effect of red blood cell folate on genome-wide methylation in cord blood: a Mendelian randomization approach. BMC Bioinformatics. 2013;14:353. doi: 10.1186/1471-2105-14-353.
-
(2013)
BMC Bioinformatics
, vol.14
, pp. 353
-
-
Binder, A.M.1
Michels, K.B.2
-
131
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
Gerken T, Girard CA, Tung YC, et al. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science. 2007;318:1469-1472. doi: 10.1126/science.1151710.
-
(2007)
Science
, vol.318
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.C.3
-
132
-
-
0026556155
-
Identifiability and exchangeability for direct and indirect effects
-
Robins JM, Greenland S. Identifiability and exchangeability for direct and indirect effects. Epidemiology. 1992;3:143-155.
-
(1992)
Epidemiology
, vol.3
, pp. 143-155
-
-
Robins, J.M.1
Greenland, S.2
-
133
-
-
84885859371
-
DNA hypomethylation, ambient particulate matter, and increased blood pressure: Findings from controlled human exposure experiments
-
Bellavia A, Urch B, Speck M, Brook RD, Scott JA, Albetti B, Behbod B, North M, Valeri L, Bertazzi PA, Silverman F, Gold D, Baccarelli AA. DNA hypomethylation, ambient particulate matter, and increased blood pressure: findings from controlled human exposure experiments. J Am Heart Assoc. 2013;2:e000212. doi: 10.1161/JAHA.113.000212.
-
(2013)
J Am Heart Assoc
, vol.2
, pp. e000212
-
-
Bellavia, A.1
Urch, B.2
Speck, M.3
Brook, R.D.4
Scott, J.A.5
Albetti, B.6
Behbod, B.7
North, M.8
Valeri, L.9
Bertazzi, P.A.10
Silverman, F.11
Gold, D.12
Baccarelli, A.A.13
-
134
-
-
84879489423
-
Blood hypomethylation of inflammatory genes mediates the effects of metal-rich airborne pollutants on blood coagulation
-
Tarantini L, Bonzini M, Tripodi A, Angelici L, Nordio F, Cantone L, Apostoli P, Bertazzi PA, Baccarelli AA. Blood hypomethylation of inflammatory genes mediates the effects of metal-rich airborne pollutants on blood coagulation. Occup Environ Med. 2013;70:418-425. doi: 10.1136/oemed-2012-101079.
-
(2013)
Occup Environ Med
, vol.70
, pp. 418-425
-
-
Tarantini, L.1
Bonzini, M.2
Tripodi, A.3
Angelici, L.4
Nordio, F.5
Cantone, L.6
Apostoli, P.7
Bertazzi, P.A.8
Baccarelli, A.A.9
-
135
-
-
0035906332
-
Zinc and the gene
-
Dreosti IE. Zinc and the gene. Mutat Res. 2001;475:161-167.
-
(2001)
Mutat Res
, vol.475
, pp. 161-167
-
-
Dreosti, I.E.1
-
136
-
-
0035906337
-
Vitamin C and genomic stability
-
Halliwell B. Vitamin C and genomic stability. Mutat Res. 2001;475:29-35.
-
(2001)
Mutat Res
, vol.475
, pp. 29-35
-
-
Halliwell, B.1
-
137
-
-
0035906329
-
Niacin, poly(ADP-ribose) polymerase-1 and genomic stability
-
Hageman GJ, Stierum RH. Niacin, poly(ADP-ribose) polymerase-1 and genomic stability. Mutat Res. 2001;475:45-56.
-
(2001)
Mutat Res
, vol.475
, pp. 45-56
-
-
Hageman, G.J.1
Stierum, R.H.2
-
138
-
-
0031816123
-
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
-
Jacob RA, Gretz DM, Taylor PC, James SJ, Pogribny IP, Miller BJ, Henning SM, Swendseid ME. Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J Nutr. 1998;128:1204-1212.
-
(1998)
J Nutr
, vol.128
, pp. 1204-1212
-
-
Jacob, R.A.1
Gretz, D.M.2
Taylor, P.C.3
James, S.J.4
Pogribny, I.P.5
Miller, B.J.6
Henning, S.M.7
Swendseid, M.E.8
-
139
-
-
17644402494
-
Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma
-
Pufulete M, Al-Ghnaniem R, Khushal A, Appleby P, Harris N, Gout S, Emery PW, Sanders TA. Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma. Gut. 2005;54:648-653. doi: 10.1136/gut.2004.054718.
-
(2005)
Gut
, vol.54
, pp. 648-653
-
-
Pufulete, M.1
Al-Ghnaniem, R.2
Khushal, A.3
Appleby, P.4
Harris, N.5
Gout, S.6
Emery, P.W.7
Sanders, T.A.8
-
140
-
-
84930656468
-
Cardiac autonomic dysfunction: Particulate air pollution effects are modulated by epigenetic immunoregulation of Toll-like receptor 2 and dietary flavonoid intake
-
Zhong J, Colicino E, Lin X, et al. Cardiac autonomic dysfunction: particulate air pollution effects are modulated by epigenetic immunoregulation of Toll-like receptor 2 and dietary flavonoid intake. J Am Heart Assoc. 2015;4:e001423. doi: 10.1161/JAHA.114.001423.
-
(2015)
J Am Heart Assoc
, vol.4
, pp. e001423
-
-
Zhong, J.1
Colicino, E.2
Lin, X.3
-
141
-
-
0032738821
-
First steps toward understanding the pathophysiologic link between air pollution and cardiac mortality
-
Stone PH, Godleski JJ. First steps toward understanding the pathophysiologic link between air pollution and cardiac mortality. Am Heart J. 1999;138:804-807.
-
(1999)
Am Heart J
, vol.138
, pp. 804-807
-
-
Stone, P.H.1
Godleski, J.J.2
-
142
-
-
33847026146
-
Changes in DNA methylation patterns in subjects exposed to low-dose benzene
-
Bollati V, Baccarelli A, Hou L, Bonzini M, Fustinoni S, Cavallo D, Byun HM, Jiang J, Marinelli B, Pesatori AC, Bertazzi PA, Yang AS. Changes in DNA methylation patterns in subjects exposed to low-dose benzene. Cancer Res. 2007;67:876-880. doi: 10.1158/0008-5472.CAN-06-2995.
-
(2007)
Cancer Res
, vol.67
, pp. 876-880
-
-
Bollati, V.1
Baccarelli, A.2
Hou, L.3
Bonzini, M.4
Fustinoni, S.5
Cavallo, D.6
Byun, H.M.7
Jiang, J.8
Marinelli, B.9
Pesatori, A.C.10
Bertazzi, P.A.11
Yang, A.S.12
-
143
-
-
73349117486
-
Atherosclerosis risk factors can impose aberrant DNA methylation patterns: A tale of traffic and homocysteine
-
Lund G, Zaina S. Atherosclerosis risk factors can impose aberrant DNA methylation patterns: a tale of traffic and homocysteine. Curr Opin Lipidol. 2009;20:448-449. doi: 10.1097/MOL.0b013e3283309928.
-
(2009)
Curr Opin Lipidol
, vol.20
, pp. 448-449
-
-
Lund, G.1
Zaina, S.2
-
144
-
-
79960133058
-
Prolonged exposure to particulate pollution, genes associated with glutathione pathways, and DNA methylation in a cohort of older men
-
Madrigano J, Baccarelli A, Mittleman MA, Wright RO, Sparrow D, Vokonas PS, Tarantini L, Schwartz J. Prolonged exposure to particulate pollution, genes associated with glutathione pathways, and DNA methylation in a cohort of older men. Environ Health Perspect. 2011;119:977-982. doi: 10.1289/ehp.1002773.
-
(2011)
Environ Health Perspect
, vol.119
, pp. 977-982
-
-
Madrigano, J.1
Baccarelli, A.2
Mittleman, M.A.3
Wright, R.O.4
Sparrow, D.5
Vokonas, P.S.6
Tarantini, L.7
Schwartz, J.8
-
145
-
-
84881010102
-
Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero
-
Koestler DC, Avissar-Whiting M, Houseman EA, Karagas MR, Marsit CJ. Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero. Environ Health Perspect. 2013;121:971-977. doi: 10.1289/ehp.1205925.
-
(2013)
Environ Health Perspect
, vol.121
, pp. 971-977
-
-
Koestler, D.C.1
Avissar-Whiting, M.2
Houseman, E.A.3
Karagas, M.R.4
Marsit, C.J.5
-
146
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
Branco MR, Ficz G, Reik W. Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet. 2012;13:7-13. doi: 10.1038/nrg3080.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
-
147
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor WA, Pape UJ, Huang Y, et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature. 2011;473:394-397. doi: 10.1038/nature10102.
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
-
148
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
-
Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K, Sun YE, Zhang Y. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev. 2011;25:679-684. doi: 10.1101/gad.2036011.
-
(2011)
Genes Dev
, vol.25
, pp. 679-684
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Wang, Z.4
Cui, K.5
Zhao, K.6
Sun, Y.E.7
Zhang, Y.8
-
149
-
-
79955055958
-
Epigenetics in cardiovascular disease
-
Shirodkar AV, Marsden PA. Epigenetics in cardiovascular disease. Curr Opin Cardiol. 2011;26:209-215. doi: 10.1097/HCO.0b013e328345986e.
-
(2011)
Curr Opin Cardiol
, vol.26
, pp. 209-215
-
-
Shirodkar, A.V.1
Marsden, P.A.2
-
150
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science. 2009;324:930-935. doi: 10.1126/science.1170116.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
Rao, A.11
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