Vitamin C and genomic stability

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 475, Issue 1-2, 2001, Pages 29-35

  Halliwell, Barry ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

DNA damage; Vitamin C

Indexed keywords

ASCORBIC ACID; CELL DNA; DNA BASE;

ANTIOXIDANT ACTIVITY; CANCER RISK; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHROMOSOME ABERRATION; DEGENERATIVE DISEASE; DIETARY INTAKE; DNA STRAND BREAKAGE; FRUIT; GENETIC STABILITY; HUMAN; MICRONUCLEUS; NONHUMAN; PRIORITY JOURNAL; REVIEW; STOMACH CARCINOMA; VEGETABLE;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; DNA; DNA DAMAGE; HUMANS;

EID: 0035906337     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(01)00072-0     Document Type: Review

References (69)

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5. Ascorbic acid and total Vitamin C concentrations in plasma, gastric juice and gastrointestinal mucosa: Effects of gastritis and oral supplementation
6. Effect of ascorbic acid dose taken with a meal on nitrosoproline excretion in subjects ingesting nitrate and proline
7. Hepatic ascorbic acid saturation is the most stringent response criterion for determining the Vitamin C requirement of juvenile European Sea Bass (Dicentrarchus labrax)
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14. 2-generating peroxisomal urate oxidase
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20. Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids
21. Long-term dietary strawberry, spinach or Vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioural deficits
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44. Vitamin C exhibits pro-oxidant properties
45. Can antioxidant vitamins materially reduce oxidative damage in humans?
46. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm
47. The effects of iron and Vitamin C co-supplementation on oxidative damage to DNA in healthy volunteers
48. 8dG in the liver of guinea pigs supplemented with graded dietary doses of ascorbic acid and α-tocopherol
49. Ex vivo assessment of lymphocyte antioxidant status using the comet assay
50. Effect of Vitamin C supplementation on chromosome damage, apoptosis and necrosis ex vivo
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55. Protective effect of Vitamins C and E on the number of micronuclei in lymphocytes in smokers and their role in ascorbate free radical formation in plasma
56. 2
57. Immunochemical detection of oxalate monoalkylamide, an ascorbate-derived Maillard reaction product in the human lens
58. Ascorbic acid therapy in a thermal burn model of corneal ulceration in rabbits
59. In vivo dual effects of vitamin C on paraquat-induced lung damage: Dependence on released metals from the damaged tissue
60. High correlation between pentosidine protein cross-links and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis
61. Novel repair action of Vitamin C upon in vivo oxidative DNA damage
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63. Chronic antioxidant use and changes in endothelial dysfunction: A review of clinical investigations
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65. Treatment of hypertension with ascorbic acid
66. Effect of Vitamin C on ambulatory blood pressure and plasma lipids in older persons
67. Vitamin C attenuates nitrate tolerance independently of its antioxidant effect