Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring

British Journal of Nutrition

Volumn 100, Issue 2, 2008, Pages 278-282

  Lillycrop, Karen A ^a   Phillips, Emma S ^a   Torrens, Christopher ^b   Hanson, Mark A ^b   Jackson, Alan A ^b   Burdge, Graham C ^b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Epigenetic regulation; Fetal programming; PPAR ; Rats

Indexed keywords

CASEIN; CYTOSINE; FOLIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FEMALE; GENE CONTROL; GENE SEQUENCE; LIVER PARENCHYMA; MALE; MATERNAL NUTRITION; NONHUMAN; PERINATAL PERIOD; POSTNATAL DEVELOPMENT; PREGNANCY; PROGENY; PROMOTER REGION; PROTEIN RESTRICTION; RAT; STATISTICAL SIGNIFICANCE; VITAMIN INTAKE;

ANIMALS; BASE SEQUENCE; CPG ISLANDS; CYTOSINE; DIET, PROTEIN-RESTRICTED; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FETAL DEVELOPMENT; LIVER; MOLECULAR SEQUENCE DATA; PPAR ALPHA; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PRENATAL NUTRITION PHYSIOLOGY; PROMOTER REGIONS (GENETICS); RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

RATTUS;

EID: 50049108528     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507894438     Document Type: Article

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