Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction

International Journal of Epidemiology

Volumn 41, Issue 1, 2012, Pages 106-115

  Talens, Rudolf P ^a   Jukema, J W ^a,b,c,d   Trompet, S ^a   Kremer, D ^a   Westendorp, R G J ^a,b   Lumey, L H ^e   Sattar, N ^f   Putter, Hein ^a   Slagboom, P E ^a,b   Heijmans, B T ^a,b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Netherlands Consortium for Healthy Ageing   (Netherlands)

^c ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^d Durrer Center for Cardiogenetic Research   (Netherlands)

^e Columbia University ^*  (United States)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Coronary heart disease; Epigenetic biomarkers; Epigenetic epidemiology; Epigenetic risk factors; Prenatal adversity

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL; CPG OLIGODEOXYNUCLEOTIDE; CYCLIC AMP; GLUCOSE; GNASAS PROTEIN; INSIGF PROTEIN; INTERLEUKIN 10; LEPTIN; PEPTIDES AND PROTEINS; PRAVASTATIN; SOMATOMEDIN B; UNCLASSIFIED DRUG;

BASELINE CONDITIONS; BLOOD; CARDIOVASCULAR DISEASE; DISEASE INCIDENCE; EPIDEMIOLOGY; MASS SPECTROMETRY; WOMENS HEALTH;

AGED; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DIABETES MELLITUS; DNA EXTRACTION; DNA METHYLATION; EPIGENETICS; FEMALE; FETUS GROWTH; FOLLOW UP; GENE CONTROL; GENE LOCUS; GENETIC ASSOCIATION; GENOME IMPRINTING; GLUCOSE METABOLISM; GROWTH, DEVELOPMENT AND AGING; HEART INFARCTION; HUMAN; HYPERTENSION; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; METABOLISM; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; PROMOTER REGION; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK REDUCTION; SEX DIFFERENCE; SMOKING;

AGED; AGED, 80 AND OVER; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FETAL NUTRITION DISORDERS; FOLLOW-UP STUDIES; GENE-ENVIRONMENT INTERACTION; GENETIC LOCI; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INCIDENCE; MALE; MYOCARDIAL INFARCTION; PRAVASTATIN; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84858636393     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyr153     Document Type: Article

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