Host genetics of severe influenza: From mouse Mx1 to human IRF7

Current Opinion in Immunology

Volumn 38, Issue , 2016, Pages 109-120

  Ciancanelli, Michael J ^a   Abel, Laurent ^a,b,c   Zhang, Shen Ying ^a,b,c   Casanova, Jean Laurent ^a,b,c,d  

^a ROCKEFELLER UNIVERSITY   (United States)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; INTERFERON; INTERFERON REGULATORY FACTOR 7; PROTEIN IFITM3; UNCLASSIFIED DRUG; VIRUS RNA; ALPHA INTERFERON; BETA INTERFERON; CYTOKINE; INTERFERON-LAMBDA PROTEIN, MOUSE; IRF7 PROTEIN, HUMAN; MX1 PROTEIN, MOUSE; MYXOVIRUS RESISTANCE PROTEIN;

B LYMPHOCYTE; CELLULAR IMMUNITY; DISEASE SEVERITY; EXOME; GENE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; GENETICS; HOST GENETICS; HOST RESISTANCE; HOST SUSCEPTIBILITY; HUMAN; IFITM3 GENE; IMMUNE DEFICIENCY; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA; INFLUENZA A VIRUS; IRF7 GENE; MOUSE; MX1 GENE; NEXT GENERATION SEQUENCING; NONHUMAN; PROTEIN FUNCTION; QUANTITATIVE TRAIT LOCUS; RANBP2 GENE; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; T LYMPHOCYTE; VIRAL GENETICS; VIRUS GENOME; VIRUS REPLICATION; ANIMAL; DEFICIENCY; DISEASE PREDISPOSITION; GENE EXPRESSION REGULATION; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; INNATE IMMUNITY; ORTHOMYXOVIRIDAE; PATHOGENICITY; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; CYTOKINES; DISEASE SUSCEPTIBILITY; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; IMMUNOCOMPROMISED HOST; INFLUENZA, HUMAN; INTERFERON REGULATORY FACTOR-7; INTERFERON-ALPHA; INTERFERON-BETA; MICE; MICE, TRANSGENIC; MYXOVIRUS RESISTANCE PROTEINS; ORTHOMYXOVIRIDAE; SIGNAL TRANSDUCTION;

EID: 84952884939     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2015.12.002     Document Type: Review

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