메뉴 건너뛰기




Volumn 86, Issue 20, 2012, Pages 10988-10998

TLR7 Recognition is dispensable for influenza virus a infection but important for the induction of hemagglutinin-specific antibodies in response to the 2009 pandemic split vaccine in mice

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M ANTIBODY; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 7; VIRUS ANTIBODY; VIRUS RNA;

EID: 84869044834     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01064-12     Document Type: Article
Times cited : (56)

References (63)
  • 1
    • 0032127279 scopus 로고    scopus 로고
    • Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
    • Adachi O, et al. 1998. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 9:143-150.
    • (1998) Immunity , vol.9 , pp. 143-150
    • Adachi, O.1
  • 2
    • 35548997439 scopus 로고    scopus 로고
    • Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic
    • Ahmed R, Oldstone MB, Palese P. 2007. Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic. Nat. Immunol. 8:1188-1193.
    • (2007) Nat. Immunol. , vol.8 , pp. 1188-1193
    • Ahmed, R.1    Oldstone, M.B.2    Palese, P.3
  • 3
    • 79751480796 scopus 로고    scopus 로고
    • The relative efficacy of trivalent live attenuated and inactivated influenza vaccines in children and adults
    • Ambrose CS, Levin MJ, Belshe RB. 2011. The relative efficacy of trivalent live attenuated and inactivated influenza vaccines in children and adults. Influenza Other Respi. Viruses 5:67-75.
    • (2011) Influenza Other Respi. Viruses , vol.5 , pp. 67-75
    • Ambrose, C.S.1    Levin, M.J.2    Belshe, R.B.3
  • 4
    • 12344263746 scopus 로고    scopus 로고
    • Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways
    • Barchet W, et al. 2005. Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways. Eur. J. Immunol. 35:236-242.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 236-242
    • Barchet, W.1
  • 5
    • 70349664422 scopus 로고    scopus 로고
    • Toll-like receptors; sentries in the B-cell response
    • Bekeredjian-Ding I, Jego G. 2009. Toll-like receptors; sentries in the B-cell response. Immunology 128:311-323.
    • (2009) Immunology , vol.128 , pp. 311-323
    • Bekeredjian-Ding, I.1    Jego, G.2
  • 6
    • 33846995457 scopus 로고    scopus 로고
    • Live attenuated versus inactivated influenza vaccine in infants and young children
    • Belshe RB, et al. 2007. Live attenuated versus inactivated influenza vaccine in infants and young children. N. Engl. J. Med. 356:685-696.
    • (2007) N. Engl. J. Med. , vol.356 , pp. 685-696
    • Belshe, R.B.1
  • 7
    • 80053445138 scopus 로고    scopus 로고
    • Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells
    • doi:10.1371/journal.pone.0025542 One
    • Boeglin E, et al. 2011. Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells. PLoS One 6:e25542. doi:10.1371/journal.pone.0025542.
    • (2011) PLoS , vol.6
    • Boeglin, E.1
  • 8
    • 80055080756 scopus 로고    scopus 로고
    • Toll-like receptor 7 controls the anti-retroviral germinal center response
    • doi:10.1371/journal.ppat. 1002293
    • Browne EP. 2011. Toll-like receptor 7 controls the anti-retroviral germinal center response. PLoS Pathog. 7:e1002293. doi:10.1371/journal.ppat. 1002293.
    • (2011) PLoS Pathog , vol.7
    • Browne, E.P.1
  • 9
    • 80455126055 scopus 로고    scopus 로고
    • Improving immunogenicity and effectiveness of influenza vaccine in older adults
    • Cao W, et al. 2011. Improving immunogenicity and effectiveness of influenza vaccine in older adults. Expert Rev. Vaccines 10:1529-1537.
    • (2011) Expert Rev. Vaccines , vol.10 , pp. 1529-1537
    • Cao, W.1
  • 10
    • 84860324628 scopus 로고    scopus 로고
    • Differential roles for RIG-I-like receptors and nucleic acid-sensing TLR pathways in controlling a chronic viral infection
    • Clingan JM, Ostrow K, Hosiawa KA, Chen ZJ, Matloubian M. 2012. Differential roles for RIG-I-like receptors and nucleic acid-sensing TLR pathways in controlling a chronic viral infection. J. Immunol. 188:4432-4440.
    • (2012) J. Immunol. , vol.188 , pp. 4432-4440
    • Clingan, J.M.1    Ostrow, K.2    Hosiawa, K.A.3    Chen, Z.J.4    Matloubian, M.5
  • 11
    • 57149107560 scopus 로고    scopus 로고
    • In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responses
    • Co MD, et al. 2009. In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responses. Vaccine 27:319-327.
    • (2009) Vaccine , vol.27 , pp. 319-327
    • Co, M.D.1
  • 12
    • 78650078441 scopus 로고    scopus 로고
    • Phylogenetic analysis of surface proteins of novel H1N1 virus isolated from 2009 pandemic
    • Danishuddin M, Khan SN, Khan AU. 2009. Phylogenetic analysis of surface proteins of novel H1N1 virus isolated from 2009 pandemic. Bioinformation 4:94-97.
    • (2009) Bioinformation , vol.4 , pp. 94-97
    • Danishuddin, M.1    Khan, S.N.2    Khan, A.U.3
  • 13
    • 0347593991 scopus 로고    scopus 로고
    • A critical role for induced IgM in the protection against West Nile virus infection
    • Diamond MS, et al. 2003. A critical role for induced IgM in the protection against West Nile virus infection. J. Exp. Med. 198:1853-1862.
    • (2003) J. Exp. Med. , vol.198 , pp. 1853-1862
    • Diamond, M.S.1
  • 16
    • 33747411261 scopus 로고    scopus 로고
    • Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses
    • Fink K, et al. 2006. Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses. Eur. J. Immunol. 36: 2094-2105.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 2094-2105
    • Fink, K.1
  • 17
    • 78650640612 scopus 로고    scopus 로고
    • Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity
    • Fotin-Mleczek M, et al. 2011. Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity. J. Immunother. 34:1-15.
    • (2011) J. Immunother , vol.34 , pp. 1-15
    • Fotin-Mleczek, M.1
  • 18
    • 50849116757 scopus 로고    scopus 로고
    • Superior immunogenicity of inactivated whole virus H5N1 influenza vaccine is primarily controlled by Toll-like receptor signalling
    • doi:10.1371/journal.ppat.1000138
    • Geeraedts F, et al. 2008. Superior immunogenicity of inactivated whole virus H5N1 influenza vaccine is primarily controlled by Toll-like receptor signalling. PLoS Pathog. 4:e1000138. doi:10.1371/journal.ppat.1000138.
    • (2008) PLoS Pathog , vol.4
    • Geeraedts, F.1
  • 19
    • 58149131467 scopus 로고    scopus 로고
    • Toll-like receptor 7-induced naive human B-cell differentiation and immunoglobulin production
    • Glaum MC, et al. 2009. Toll-like receptor 7-induced naive human B-cell differentiation and immunoglobulin production. J. Allergy Clin. Immunol. 123:224-230.e4.
    • (2009) J. Allergy Clin. Immunol. , vol.123
    • Glaum, M.C.1
  • 20
    • 0002051540 scopus 로고    scopus 로고
    • BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT
    • Hall TA. 1999. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp. Ser. 41:95-98.
    • (1999) Nucleic Acids Symp. Ser. , vol.41 , pp. 95-98
    • Hall, T.A.1
  • 21
    • 49249088078 scopus 로고    scopus 로고
    • Comparison of human B cell activation by TLR7 and TLR9 agonists
    • doi:10.1186/1471-2172-9-39
    • Hanten JA, et al. 2008. Comparison of human B cell activation by TLR7 and TLR9 agonists. BMC Immunol. 9:39. doi:10.1186/1471-2172-9-39.
    • (2008) BMC Immunol , vol.9 , pp. 39
    • Hanten, J.A.1
  • 22
    • 33846937311 scopus 로고    scopus 로고
    • TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses
    • Heer AK, et al. 2007. TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses. J. Immunol. 178: 2182-2191.
    • (2007) J. Immunol. , vol.178 , pp. 2182-2191
    • Heer, A.K.1
  • 24
    • 79952745936 scopus 로고    scopus 로고
    • Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response
    • Hou B, et al. 2011. Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response. Immunity 34:375-384.
    • (2011) Immunity , vol.34 , pp. 375-384
    • Hou, B.1
  • 25
    • 60549112774 scopus 로고    scopus 로고
    • Inflammasome recognition of influenza virus is essential for adaptive immune responses
    • Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A. 2009. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J. Exp. Med. 206:79-87.
    • (2009) J. Exp. Med. , vol.206 , pp. 79-87
    • Ichinohe, T.1    Lee, H.K.2    Ogura, Y.3    Flavell, R.4    Iwasaki, A.5
  • 26
    • 69149093400 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of new swineorigin H1N1 influenza viruses
    • Itoh Y, et al. 2009. In vitro and in vivo characterization of new swineorigin H1N1 influenza viruses. Nature 460:1021-1025.
    • (2009) Nature , vol.460 , pp. 1021-1025
    • Itoh, Y.1
  • 27
    • 80053092279 scopus 로고    scopus 로고
    • Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice
    • doi:10.1371/journal.pone.0025242
    • Jeisy-Scott V, et al. 2011. Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice. PLoS One 6:e25242. doi:10.1371/journal.pone.0025242.
    • (2011) PLoS One , vol.6
    • Jeisy-Scott, V.1
  • 28
    • 80055115679 scopus 로고    scopus 로고
    • MyD88 plays an essential role in inducing B cells capable of differentiating into antibody-secreting cells after vaccination
    • Kang SM, et al. 2011. MyD88 plays an essential role in inducing B cells capable of differentiating into antibody-secreting cells after vaccination. J. Virol. 85:11391-11400.
    • (2011) J. Virol. , vol.85 , pp. 11391-11400
    • Kang, S.M.1
  • 29
    • 79955505656 scopus 로고    scopus 로고
    • Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets
    • Kastenmuller K, et al. 2011. Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets. J. Clin. Invest. 121:1782-1796.
    • (2011) J. Clin. Invest , vol.121 , pp. 1782-1796
    • Kastenmuller, K.1
  • 30
    • 79952173864 scopus 로고    scopus 로고
    • Programming the magnitude and persistence of antibody responses with innate immunity
    • Kasturi SP, et al. 2011. Programming the magnitude and persistence of antibody responses with innate immunity. Nature 470:543-547.
    • (2011) Nature , vol.470 , pp. 543-547
    • Kasturi, S.P.1
  • 32
    • 0031804870 scopus 로고    scopus 로고
    • Low CD3_CD28-induced interleukin-2 production correlates with decreased reactive oxygen intermediate formation in neonatal T cells
    • Kilpinen S, Hurme M. 1998. Low CD3_CD28-induced interleukin-2 production correlates with decreased reactive oxygen intermediate formation in neonatal T cells. Immunology 94:167-172.
    • (1998) Immunology , vol.94 , pp. 167-172
    • Kilpinen, S.1    Hurme, M.2
  • 33
    • 0036687929 scopus 로고    scopus 로고
    • Role of IgM antibodies versus B cells in influenza virus-specific immunity
    • Kopf M, Brombacher F, Bachmann MF. 2002. Role of IgM antibodies versus B cells in influenza virus-specific immunity. Eur. J. Immunol. 32: 2229-2236.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2229-2236
    • Kopf, M.1    Brombacher, F.2    Bachmann, M.F.3
  • 34
    • 77952982038 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes
    • doi10.1126/scitranslmed.3000759
    • Koyama S, et al. 2010. Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes. Sci. Transl. Med. 2:25ra24. doi10.1126/scitranslmed.3000759.
    • (2010) Sci. Transl. Med , vol.2
    • Koyama, S.1
  • 35
    • 38949117752 scopus 로고    scopus 로고
    • Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination
    • Koyama S, et al. 2007. Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination. J. Immunol. 179:4711-4720.
    • (2007) J. Immunol. , vol.179 , pp. 4711-4720
    • Koyama, S.1
  • 37
    • 34247622766 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity in B-cell activation and antibody responses
    • Lanzavecchia A, Sallusto F. 2007. Toll-like receptors and innate immunity in B-cell activation and antibody responses. Curr. Opin. Immunol. 19:268-274.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 268-274
    • Lanzavecchia, A.1    Sallusto, F.2
  • 38
    • 9144238160 scopus 로고    scopus 로고
    • TLR-independent induction of dendritic cell maturation and adaptive immunity by negative-strand RNA viruses
    • Lopez CB, et al. 2004. TLR-independent induction of dendritic cell maturation and adaptive immunity by negative-strand RNA viruses. J. Immunol. 173:6882-6889.
    • (2004) J. Immunol. , vol.173 , pp. 6882-6889
    • Lopez, C.B.1
  • 39
    • 77958008216 scopus 로고    scopus 로고
    • Intranasal vaccination with messenger RNA as a new approach in gene therapy: use against tuberculosis
    • doi:10.1186/1472-6750-10-77
    • Lorenzi JC, et al. 2010. Intranasal vaccination with messenger RNA as a new approach in gene therapy: use against tuberculosis. BMC Biotechnol. 10:77. doi:10.1186/1472-6750-10-77.
    • (2010) BMC Biotechnol , vol.10 , pp. 77
    • Lorenzi, J.C.1
  • 40
    • 1842631428 scopus 로고    scopus 로고
    • Recognition of single-stranded RNA viruses by Toll-like receptor 7
    • Lund JM, et al. 2004. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc. Natl. Acad. Sci. U. S. A. 101:5598-5603.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 5598-5603
    • Lund, J.M.1
  • 41
    • 37549034962 scopus 로고    scopus 로고
    • B cell intrinsic TLR signals amplify but are not required for humoral immunity
    • Meyer-Bahlburg A, Khim S, Rawlings DJ. 2007. B cell intrinsic TLR signals amplify but are not required for humoral immunity. J. Exp. Med. 204:3095-3101.
    • (2007) J. Exp. Med. , vol.204 , pp. 3095-3101
    • Meyer-Bahlburg, A.1    Khim, S.2    Rawlings, D.J.3
  • 42
    • 79953770830 scopus 로고    scopus 로고
    • The first influenza pandemic of the new millennium
    • Neumann G, Kawaoka Y. 2011. The first influenza pandemic of the new millennium. Influenza Other Respi. Viruses 5:157-166.
    • (2011) Influenza Other Respi. Viruses , vol.5 , pp. 157-166
    • Neumann, G.1    Kawaoka, Y.2
  • 43
    • 0032787091 scopus 로고    scopus 로고
    • Control of early viral and bacterial distribution and disease by natural antibodies
    • Ochsenbein AF, et al. 1999. Control of early viral and bacterial distribution and disease by natural antibodies. Science 286:2156-2159.
    • (1999) Science , vol.286 , pp. 2156-2159
    • Ochsenbein, A.F.1
  • 44
    • 31344450870 scopus 로고    scopus 로고
    • Making better influenza virus vaccines?
    • Palese P. 2006. Making better influenza virus vaccines? Emerg. Infect. Dis. 12:61-65.
    • (2006) Emerg. Infect. Dis , vol.12 , pp. 61-65
    • Palese, P.1
  • 45
    • 78650754831 scopus 로고    scopus 로고
    • Inflammasomes as mediators of immunity against influenza virus
    • Pang IK, Iwasaki A. 2011. Inflammasomes as mediators of immunity against influenza virus. Trends Immunol. 32:34-41.
    • (2011) Trends Immunol , vol.32 , pp. 34-41
    • Pang, I.K.1    Iwasaki, A.2
  • 46
    • 79952282195 scopus 로고    scopus 로고
    • Different B cell populations mediate early and late memory during an endogenous immune response
    • Pape KA, Taylor JJ, Maul RW, Gearhart PJ, Jenkins MK. 2011. Different B cell populations mediate early and late memory during an endogenous immune response. Science 331:1203-1207.
    • (2011) Science , vol.331 , pp. 1203-1207
    • Pape, K.A.1    Taylor, J.J.2    Maul, R.W.3    Gearhart, P.J.4    Jenkins, M.K.5
  • 47
    • 27844541797 scopus 로고    scopus 로고
    • Control of B-cell responses by Toll-like receptors
    • Pasare C, Medzhitov R. 2005. Control of B-cell responses by Toll-like receptors. Nature 438:364-368.
    • (2005) Nature , vol.438 , pp. 364-368
    • Pasare, C.1    Medzhitov, R.2
  • 48
    • 33745158157 scopus 로고
    • A simple method of estimating fifty per cent endpoints
    • Reed, L. J., andH. Muench. 1938. A simple method of estimating fifty per cent endpoints. Am. J. Hyg. 27:493-497.
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 49
    • 73949098473 scopus 로고    scopus 로고
    • Estimates of the prevalence of pandemic (H1N1) 2009 United States
    • Reed C, et al. 2009. Estimates of the prevalence of pandemic (H1N1) 2009, United States, April-July 2009. Emerg. Infect. Dis. 15:2004-2007.
    • (2009) April-July 2009. Emerg. Infect. Dis , vol.15 , pp. 2004-2007
    • Reed, C.1
  • 50
    • 33645956556 scopus 로고    scopus 로고
    • Toll-like receptor stimulation as a third signal required for activation of human naive B cells
    • Ruprecht CR, Lanzavecchia A. 2006. Toll-like receptor stimulation as a third signal required for activation of human naive B cells. Eur. J. Immunol. 36:810-816.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 810-816
    • Ruprecht, C.R.1    Lanzavecchia, A.2
  • 51
    • 0035414579 scopus 로고    scopus 로고
    • Heterosubtypic immunity against human influenza A viruses, including recently emerged avian H5 and H9 viruses, induced by FLU-ISCOM vaccine in mice requires both cytotoxic T-lymphocyte and macrophage function
    • Sambhara S, et al. 2001. Heterosubtypic immunity against human influenza A viruses, including recently emerged avian H5 and H9 viruses, induced by FLU-ISCOM vaccine in mice requires both cytotoxic T-lymphocyte and macrophage function. Cell. Immunol. 211:143-153.
    • (2001) Cell. Immunol. , vol.211 , pp. 143-153
    • Sambhara, S.1
  • 52
    • 78649423252 scopus 로고    scopus 로고
    • MyD88 signaling is indispensable for primary influenza A virus infection but dispensable for secondary infection
    • Seo S-U, et al. 2010. MyD88 signaling is indispensable for primary influenza A virus infection but dispensable for secondary infection. J. Virol. 84:12713-12722.
    • (2010) J. Virol. , vol.84 , pp. 12713-12722
    • Seo, S.-U.1
  • 53
    • 79956076226 scopus 로고    scopus 로고
    • Toward self-adjuvanting subunit vaccines: model peptide and protein antigens incorporating covalently bound Toll-like receptor-7 agonistic imidazoquinolines
    • Shukla NM, et al. 2011. Toward self-adjuvanting subunit vaccines: model peptide and protein antigens incorporating covalently bound Toll-like receptor-7 agonistic imidazoquinolines. Bioorg. Med. Chem. Lett. 21: 3232-3236.
    • (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 3232-3236
    • Shukla, N.M.1
  • 54
    • 84880666503 scopus 로고    scopus 로고
    • Influenza: propagation, quantificationand storage
    • Chapter 15:Unit 15G
    • Szretter KJ, Balish AL, Katz JM. 2006. Influenza: propagation, quantification, and storage. Curr. Protoc. Microbiol. Chapter 15:Unit 15G.1.
    • (2006) Curr. Protoc. Microbiol , pp. 1
    • Szretter, K.J.1    Balish, A.L.2    Katz, J.M.3
  • 56
    • 34347216401 scopus 로고    scopus 로고
    • The origin and virulence of the 1918 "Spanish" influenza virus
    • Taubenberger JK. 2006. The origin and virulence of the 1918 "Spanish" influenza virus. Proc. Am. Philos. Soc. 150:86-112.
    • (2006) Proc. Am. Philos. Soc. , vol.150 , pp. 86-112
    • Taubenberger, J.K.1
  • 57
    • 60449095987 scopus 로고    scopus 로고
    • Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production
    • Tsukamoto Y, et al. 2009. Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production. Mol. Immunol. 46:1278-1288.
    • (2009) Mol. Immunol. , vol.46 , pp. 1278-1288
    • Tsukamoto, Y.1
  • 58
    • 80054024974 scopus 로고    scopus 로고
    • Oil-in-water emulsion adjuvant with influenza vaccine in young children
    • Vesikari T, et al. 2011. Oil-in-water emulsion adjuvant with influenza vaccine in young children. N. Engl. J. Med. 365:1406-1416.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 1406-1416
    • Vesikari, T.1
  • 59
    • 0033970454 scopus 로고    scopus 로고
    • Human Tc1 and Tc2/Tc0 CD8 T-cell clones display distinct cell surface and functional phenotypes
    • Vukmanovic-Stejic M, Vyas B, Gorak-Stolinska P, Noble A, Kemeny DM. 2000. Human Tc1 and Tc2/Tc0 CD8 T-cell clones display distinct cell surface and functional phenotypes. Blood 95:231-240.
    • (2000) Blood , vol.95 , pp. 231-240
    • Vukmanovic-Stejic, M.1    Vyas, B.2    Gorak-Stolinska, P.3    Noble, A.4    Kemeny, D.M.5
  • 60
    • 78650642085 scopus 로고    scopus 로고
    • Influenza A infection enhances cross-priming of CD8_ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion
    • Wei J, et al. 2010. Influenza A infection enhances cross-priming of CD8_ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion. J. Immunol. 185:6013-6022.
    • (2010) J. Immunol , vol.185 , pp. 6013-6022
    • Wei, J.1
  • 61
    • 77957667097 scopus 로고    scopus 로고
    • WHO. 2009. WHO, Geneva, Switzerland
    • WHO. 2009. 2009. Influenza (seasonal) fact sheet. WHO, Geneva, Switzerland.
    • (2009) Influenza (seasonal) fact sheet
  • 62
    • 20444430129 scopus 로고    scopus 로고
    • Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8_ T cell responses
    • Wille-Reece U, Wu CY, Flynn BJ, Kedl RM, Seder RA. 2005. Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8_ T cell responses. J. Immunol. 174:7676-7683.
    • (2005) J. Immunol. , vol.174 , pp. 7676-7683
    • Wille-Reece, U.1    Wu, C.Y.2    Flynn, B.J.3    Kedl, R.M.4    Seder, R.A.5
  • 63
    • 35448975223 scopus 로고    scopus 로고
    • Properties and function of polyreactive antibodies and polyreactive antigen-binding B cells
    • Zhou ZH, Tzioufas AG, Notkins AL. 2007. Properties and function of polyreactive antibodies and polyreactive antigen-binding B cells. J. Autoimmun. 29:219-228.
    • (2007) J. Autoimmun. , vol.29 , pp. 219-228
    • Zhou, Z.H.1    Tzioufas, A.G.2    Notkins, A.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.