Human pluripotent stem cells: Prospects and challenges as a source of cardiomyocytes for in vitro modeling and cell-based cardiac repair

Advanced Drug Delivery Reviews

Volumn 96, Issue , 2016, Pages 3-17

  Hartman, Matthew E ^a,b,c,d   Dai, Dao Fu ^c,d,e   Laflamme, Michael A ^c,d,e  

^a Department of Medicine   (United States)

^b Department of Genome Sciences ^*  (United States)

^c Institute for Stem Cells and Regenerative Medicine   (United States)

^d Center for Cardiovascular Biology   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cardiac regeneration; Cardiac repair; Cardiovascular disease; Disease modeling; Drug discovery; Embryonic stem cells; Heart failure; Induced pluripotent stem cells

Indexed keywords

CARDIOLOGY; CELL DEATH; DIAGNOSIS; DISEASE CONTROL; HEART; REPAIR;

CARDIAC REGENERATION; CARDIAC REPAIR; CARDIO-VASCULAR DISEASE; DISEASE MODELING; DRUG DISCOVERY; EMBRYONIC STEM CELLS; HEART FAILURE; INDUCED PLURIPOTENT STEM CELLS;

STEM CELLS;

ACTIVIN; ALPHA ACTININ; ATRIAL NATRIURETIC FACTOR; BONE MORPHOGENETIC PROTEIN 4; CALCIUM; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; DNA; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; MYOSIN HEAVY CHAIN ALPHA; MYOSIN HEAVY CHAIN BETA; MYOSIN LIGHT CHAIN 2; OCTAMER TRANSCRIPTION FACTOR 4; ODULIMOMAB; PROTEIN NODAL; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR SOX2; TROPONIN I; TROPONIN T; WNT PROTEIN;

ARRHYTHMOGENESIS; CALCIUM TRANSPORT; CARCINOGENICITY; CARDIOVASCULAR DISEASE; CELL DEATH; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL MATURATION; CELL POPULATION; CELL STRUCTURE; CHROMOSOME ABERRATION; CLINICAL PROTOCOL; DISEASE MODEL; DNA MODIFICATION; DRUG RESEARCH; DRUG SAFETY; DRUG SCREENING; EMBRYOLOGY; EMBRYONIC STEM CELL; ENDODERM; EXTRACELLULAR MATRIX; GRAFT REJECTION; HEART ARRHYTHMIA; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL RESPIRATION; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; STEM CELL TRANSPLANTATION; TERATOMA; WNT SIGNALING PATHWAY; ANIMAL; BIOLOGICAL MODEL; CARDIAC MUSCLE CELL; CELL SEPARATION; CYTOLOGY; HEART DISEASES; MESODERM; TISSUE ENGINEERING; TRANSPLANTATION;

ANIMALS; CELL DIFFERENTIATION; CELL SEPARATION; EMBRYONIC STEM CELLS; ENDODERM; HEART DISEASES; HUMANS; MESODERM; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS; TISSUE ENGINEERING;

EID: 84951860090     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2015.05.004     Document Type: Review

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