Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development

Developmental Dynamics

Volumn 243, Issue 3, 2014, Pages 381-392

  Nelson, Daryl O ^a   Jin, Dexter X ^a   Downs, Karen M ^a   Kamp, Timothy J ^a   Lyons, Gary E ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Cardiogenesis; Differentiation; Heart fields

Indexed keywords

ANIMALS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART VENTRICLES; HOMEODOMAIN PROTEINS; MICE; MICE, INBRED BALB C; MYOCARDIUM; MYOCYTES, CARDIAC; ORGAN SPECIFICITY; ORGANOGENESIS;

EID: 84894243644     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.24078     Document Type: Article

References (44)

1. Abu-Issa R, Waldo K, Kirby ML. 2004. Heart fields: one, two or more? Dev Biol 272:281-285.
2. Anderson RH, Webb S, Brown NA, Lamers W, Moorman A. 2003. Development of the heart: (2) Septation of the atriums and ventricles. Heart 89:949-958.
3. Bao ZZ, Bruneau BG, Seidman JG, Seidman CE, Cepko CL. 1999. Regulation of chamber-specific gene expression in the developing heart by Irx4. Science 283:1161-1164.
4. Bersell K, Arab S, Haring B, Kuhn B. 2009. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 138:257-270.
5. Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE. 2000. Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand. Dev Biol 217:266-277.
6. Bruneau BG, Bao ZZ, Fatkin D, Xavier-Neto J, Georgakopoulos D, Maguire CT, Berul CI, Kass DA, Kuroski-de Bold ML, de Bold AJ, Conner DA, Rosenthal N, Cepko CL, Seidman CE, Seidman JG. 2001. Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression. Mol Cell Biol 21:1730-1736.
7. Champlin AK, Dorr DL, Gates AH. 1973. Determining the stage of the estrous cycle in the mouse by the appearance of the vagina. Biol Reprod 8:491-494.
8. Chen HW, Yu SL, Chen WJ, Yang PC, Chien CT, Chou HY, Li HN, Peck K, Huang CH, Lin FY, Chen JJ, Lee YT. 2004. Dynamic changes of gene expression profiles during postnatal development of the heart in mice. Heart 90:927-934.
9. Christoffels VM, Habets PE, Franco D, Campione M, de Jong F, Lamers WH, Bao ZZ, Palmer S, Biben C, Harvey RP, Moorman AF. 2000a. Chamber formation and morphogenesis in the developing mammalian heart. Dev Biol 223:266-278.
10. Christoffels VM, Keijser AG, Houweling AC, Clout DE, Moorman AF. 2000b. Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart. Dev Biol 224:263-274.
11. David R, Jarsch VB, Schwarz F, Nathan P, Gegg M, Lickert H, Franz WM. 2011. Induction of MesP1 by Brachyury(T) generates the common multipotent cardiovascular stem cell. Cardiovasc Res 92:115-122.
12. Domian IJ, Chiravuri M, van der Meer P, Feinberg AW, Shi X, Shao Y, Wu SM, Parker KK, Chien KR. 2009. Generation of functional ventricular heart muscle from mouse ventricular progenitor cells. Science 326:426-429.
13. Downs KM, Davies T. 1993. Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development 118:1255-1266.
14. Dyer LA, Kirby ML. 2009. The role of secondary heart field in cardiac development. Dev Biol 336:137-144.
15. Engleka KA, Manderfield LJ, Brust RD, Li L, Cohen A, Dymecki SM, Epstein JA. 2012. Islet1 derivatives in the heart are of both neural crest and second heart field origin. Circ Res 110:922-926.
16. Evans SM, Yelon D, Conlon FL, Kirby ML. 2010. Myocardial lineage development. Circ Res 107:1428-1444.
17. Fishman GI. 2005. Understanding conduction system development: a hop, skip and jump away? Circ Res 96:809-811.
18. Francou A, Saint-Michel E, Mesbah K, Theveniau-Ruissy M, Rana MS, Christoffels VM, Kelly RG. 2013. Second heart field cardiac progenitor cells in the early mouse embryo. Biochim Biophys Acta 1833:795-798.
19. Fukuda M, Asano S, Nakamura T, Adachi M, Yoshida M, Yanagida M, Nishida E. 1997. CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature 390:308-311.
20. Herrmann F, Bundschu K, Kuhl SJ, Kuhl M. 2011. Tbx5 overexpression favors a first heart field lineage in murine embryonic stem cells and in Xenopus laevis embryos. Dev Dyn 240:2634-2645.
21. Kim KH, Rosen A, Bruneau BG, Hui CC, Backx PH. 2012. Iroquois homeodomain transcription factors in heart development and function. Circ Res 110:1513-1524.
22. Kitajima S, Takagi A, Inoue T, Saga Y. 2000. MesP1 and MesP2 are essential for the development of cardiac mesoderm. Development 127:3215-3226.
23. Kubalak SW, Miller-Hance WC, O'Brien TX, Dyson E, Chien KR. 1994. Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis. J Biol Chem 269:16961-16970.
24. Kudo N, Wolff B, Sekimoto T, Schreiner EP, Yoneda Y, Yanagida M, Horinouchi S, Yoshida M. 1998. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp Cell Res 242:540-547.
25. Kulisz A, Simon HG. 2008. An evolutionarily conserved nuclear export signal facilitates cytoplasmic localization of the Tbx5 transcription factor. Mol Cell Biol 28:1553-1564.
26. Li F, Wang X, Capasso JM, Gerdes AM. 1996. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J Mol Cell Cardiol 28:1737-1746.
27. Liang X, Wang G, Lin L, Lowe J, Zhang Q, Bu L, Chen YH, Chen J, Sun Y, Evans SM. 2013. HCN4 dynamically marks the first heart field and conduction system precursors. Circ Res 113:399-407.
28. Liu Z, Yue S, Chen X, Kubin T, Braun T. 2010. Regulation of cardiomyocyte polyploidy and multinucleation by CyclinG1. Circ Res 106:1498-1506.
29. Ma Q, Zhou B, Pu WT. 2008. Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity. Dev Biol 323:98-104.
30. Mahmoud AI, Kocabas F, Muralidhar SA, Kimura W, Koura AS, Thet S, Porrello ER, Sadek HA. 2013. Meis1 regulates postnatal cardiomyocyte cell cycle arrest. Nature 497:249-253.
31. Moorman A, Webb S, Brown NA, Lamers W, Anderson RH. 2003. Development of the heart: (1) formation of the cardiac chambers and arterial trunks. Heart 89:806-814.
32. Moretti A, Caron L, Nakano A, Lam JT, Bernshausen A, Chen Y, Qyang Y, Bu L, Sasaki M, Martin-Puig S, Sun Y, Evans SM, Laugwitz KL, Chien KR. 2006. Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 127:1151-1165.
33. Munoz JP, Collao A, Chiong M, Maldonado C, Adasme T, Carrasco L, Ocaranza P, Bravo R, Gonzalez L, Diaz-Araya G, Hidalgo C, Lavandero S. 2009. The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling. Biochem Biophys Res Commun 388:155-160.
34. Porrello ER, Mahmoud AI, Simpson E, Hill JA, Richardson JA, Olson EN, Sadek HA. 2011. Transient regenerative potential of the neonatal mouse heart. Science 331:1078-1080.
35. Porrello ER, Johnson BA, Aurora AB, Simpson E, Nam YJ, Matkovich SJ, Dorn GW Jr, van Rooij E, Olson EN. 2013. MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes. Circ Res 109:670-679.
36. Reynolds JO, Chiang DY, Wang W, Beavers DL, Dixit SS, Skapura DG, Landstrom AP, Song LS, Ackerman MJ, Wehrens XH. 2013. Junctophilin-2 is necessary for T-tubule maturation during mouse heart development. Cardiovasc Res 100:44-53.
37. Saga Y, Kitajima S, Miyagawa-Tomita S. 2000. Mesp1 expression is the earliest sign of cardiovascular development. Trends Cardiovasc Med 10:345-352.
38. Sedmera D, Thompson RP. 2011. Myocyte proliferation in the developing heart. Dev Dyn 240:1322-1334.
39. Solloway MJ, Harvey RP. 2003. Molecular pathways in myocardial development: a stem cell perspective. Cardiovasc Res 58:264-277.
40. Sun Q, Carrasco YP, Hu Y, Guo X, Mirzaei H, Macmillan J, Chook YM. 2013. Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc Natl Acad Sci U S A 110:1303-1308.
41. Sun Y, Liang X, Najafi N, Cass M, Lin L, Cai CL, Chen J, Evans SM. 2007. Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells. Dev Biol 304:286-296.
42. Verzi MP, McCulley DJ, De Val S, Dodou E, Black BL. 2005. The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field. Dev Biol 287:134-145.
43. Vincent SD, Buckingham ME. 2010. How to make a heart: the origin and regulation of cardiac progenitor cells. Curr Top Dev Biol 90:1-41.
44. Wu SM, Fujiwara Y, Cibulsky SM, Clapham DE, Lien CL, Schultheiss TM, Orkin SH. 2006. Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell 127:1137-1150.