Non-cardiomyocytes influence the electrophysiological maturation of human embryonic stem cell-derived cardiomyocytes during differentiation

Stem Cells and Development

Volumn 19, Issue 6, 2010, Pages 783-795

  Kim, Changsung ^a   Majdi, Maryam ^a   Xia, Peng ^a   Wei, Karen A ^a,b   Talantova, Maria ^a   Spiering, Sean ^a   Nelson, Brandon ^a   Mercola, Mark ^a   Chen, Huei Sheng Vincent ^a,c  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ION CHANNEL; PUROMYCIN; SODIUM CHANNEL;

ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL MATURATION; CELL POPULATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EMBRYONIC STEM CELL; FROZEN SECTION; HEART AUTOMATICITY; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PACEMAKER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOLEMMA;

ACTION POTENTIALS; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL LINE; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; ELECTROPHYSIOLOGICAL PHENOMENA; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INTRACELLULAR SPACE; ION CHANNEL GATING; MUSCLE PROTEINS; MYOCYTES, CARDIAC; PUROMYCIN; PYRIMIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM CHANNELS; SPHEROIDS, CELLULAR; TETRODOTOXIN;

LENTIVIRUS;

EID: 77954202607     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2009.0349     Document Type: Article

References (31)

1. Smith RR, L Barile, E Messina and E Marb. (2008). Stem cells in the heart: what's the buzz all about? Part 2: Arrhythmic risks and clinical studies. Heart Rhythm 5: 880-887.
2. Kehat I, L Khimovich, O Caspi, A Gepstein, R Shofti, G Arbel, I Huber, J Satin, J Itskovitz-Eldor and L Gepstein. (2004). Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol 22: 1282-1289. (Pubitemid 39341201)
3. Mummery C, D Ward-van Oostwaard, P Doevendans, R Spijker, S van den Brink, R Hassink, M van der Heyden, T Opthof, M Pera, AB de la Riviere, R Passier and L Tertoolen. (2003). Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation 107: 2733-2740.
4. He JQ, Y Ma, Y Lee, JA Thomson and TJ Kamp. (2003). Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ Res 93: 32-39.
5. Satin J, I Kehat, O Caspi, I Huber, G Arbel, I Itzhaki, J Magyar, EA Schroder, I Perlman and L Gepstein. (2004). Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes. J Physiol (Lond) 559 (Pt 2): 479-496. (Pubitemid 39263813)
6. Janse MK, RH Anderson, FJ van Capelle and D Durrer. (1976). A combined electrophysiological and anatomical study of the human fetal heart. Am Heart J 91: 556-562.
7. Dobrzynski H, MR Boyett and RH Anderson. (2007). New insights into pacemaker activity: promoting understanding of sick sinus syndrome. Circulation 115: 1921-1932.
8. Lakatta EG, T Vinogradova, A Lyashkov, S Sirenko, W Zhu, A Ruknudin and VA Maltsev. (2006). The integration of spontaneous intracellular Ca 2+ cycling and surface membrane ion channel activation entrains normal automaticity in cells of the heart's pacemaker. Ann N Y Acad Sci 1080: 178-206.
9. Boheler KR, J Czyz, D Tweedie, HT Yang, SV Anisimov and AM Wobus. (2002). Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ Res 91: 189-201.
10. Yanagi K, M Takano, G Narazaki, H Uosaki, T Hoshino, T Ishii, T Misaki and JK Yamashita. (2007). Hyperpolarization-activated cyclic nucleotide-gated channels and T-type calcium channels confer automaticity of embryonic stem cell-derived cardiomyocytes. Stem Cells 25: 2712-2719.
11. Sartiani L, E Bettiol, F Stillitano, A Mugelli, E Cerbai and ME Jaconi. (2007). Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach. Stem Cells 25: 1136-1144.
12. Dolnikov K, M Shilkrut, N Zeevi-Levin, S Gerecht-Nir, M Amit, A Danon, J Itskovitz-Eldor and O Binah. (2006). Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca 2+ handling and the role of sarcoplasmic reticulum in the contraction. Stem Cells 24: 236-245.
13. Liu J, JD Fu, CW Siu and RA Li. (2007). Functional sarcoplasmic reticulum for calcium handling of human embryonic stem cellderived cardiomyocytes: insights for driven maturation. Stem Cells 25: 3038-3044.
14. Davies MP, RH An, P Doevendans, S Kubalak, KR Chien and RS Kass. (1996). Developmental changes in ionic channel activity in the embryonic murine heart. Circ Res 78: 15-25.
15. Yasui K, W Liu, T Opthof, K Kada, JK Lee, K Kamiya and I Kodama. (2001). I(f) current and spontaneous activity in mouse embryonic ventricular myocytes. Circ Res 88: 536-542.
16. Eisenberg LM and RR Markwald. (2004). Cellular recruitment and the development of the myocardium. Dev Biol 274: 225-232.
17. Kita-Matsuo H, M Barcova, N Prigozhina, N Salomonis, K Wei, JG Jacot, B Nelson, S Spiering, R Haverslag, C Kim, M Talantova, R Bajpai, D Calzolari, A Terskikh, AD McCulloch, JH Price, BR Conklin, HS Chen and M Mercola. (2009). Lentiviral vectors and protocols for creation of stable hESC lines for fl uorescent tracking and drug resistance selection of cardiomyocytes. PLoS ONE 4: e5046.
18. Huber I, I Itzhaki, O Caspi, G Arbel, M Tzukerman, A Gepstein, M Habib, L Yankelson, I Kehat and L Gepstein. (2007). Identifi cation and selection of cardiomyocytes during human embryonic stem cell differentiation. FASEB J 21: 2551-2563.
19. My A, F Aimond, C Mard, K Mikoshiba, M Michalak and M Puct. (2005). Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling. Mol Biol Cell 16: 2414-2423.
20. Viswanathan S, JB Burch, GI Fishman, IP Moskowitz and DW Benson. (2007). Characterization of sinoatrial node in four conduction system marker mice. J Mol Cell Cardiol 42: 946-953.
21. Watanabe Y, Y Koide and J Kimura. (2006). Topics on the Na + / Ca 2+ exchanger: pharmacological characterization of Na + /Ca 2+ exchanger inhibitors. J Pharmacol Sci 102: 7-16.
22. Gysembergh A, S Lemaire, C Piot, C Sportouch, S Richard, RA Kloner and K Przyklenk. (1999). Pharmacological manipulation of Ins(1,4,5)P3 signaling mimics preconditioning in rabbit heart. Am J Physiol 277 (6 Pt 2): H2458-H2469.
23. Barbuti A and D DiFrancesco. (2008). Control of cardiac rate by "funny" channels in health and disease. Ann N Y Acad Sci 1123: 213-223.
24. Briggs I, RE BoSmith and CG Heapy. (1994). Effects of Zeneca ZD7288 in comparison with alinidine and UL-FS 49 on guinea pig sinoatrial node and ventricular action potentials. J Cardiovasc Pharmacol 24: 380-387.
25. Guo XT, A Uehara, A Ravindran, SH Bryant, S Hall and E Moczydlowski. (1987). Kinetic basis for insensitivity to tetrodotoxin and saxitoxin in sodium channels of canine heart and denervated rat skeletal muscle. Biochemistry 26: 7546-7556.
26. Molnar J, JS Weiss and JE Rosenthal. (1995). The missing second: what is the correct unit for the Bazett corrected QT interval? Am J Cardiol 75: 537-538.
27. Satin J, I Itzhaki, S Rapoport, EA Schroder, L Izu, G Arbel, R Beyar, CW Balke, J Schiller and L Gepstein. (2008). Calcium handling in human embryonic stem cell-derived cardiomyocytes. Stem Cells 26: 1961-1972.
28. High FA and JA Epstein. (2008). The multifaceted role of Notch in cardiac development and disease. Nat Rev Genet 9: 49-61.
29. Kapur N and K Banach. (2007). Inositol-1,4,5-trisphosphatemediated spontaneous activity in mouse embryonic stem cellderived cardiomyocytes. J Physiol (Lond) 581 (Pt 3): 1113-1127.
30. Mangoni ME, B Couette, L Marger, E Bourinet, J Striessnig and J Nargeot. (2006). Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes. Prog Biophys Mol Biol 90: 38-63. (Pubitemid 41721043)
31. Nerbonne JM. (1998). Regulation of voltage-gated K + channel expression in the developing mammalian myocardium. J Neurobiol 37: 37-59.