Cardiac excitation-contraction coupling

Nature

Volumn 415, Issue 6868, 2002, Pages 198-205

  Bers, Donald M ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CELLS; IONS; PHYSIOLOGY;

EXCITATION-CONTRACTION COUPLING;

BIOLOGICAL ORGANS;

ION CHANNEL;

BIOLOGY;

CALCIUM TRANSPORT; CELL ORGANELLE; EXCITATION CONTRACTION COUPLING; HEART CONTRACTION; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; PRIORITY JOURNAL; REVIEW;

ANIMALS; CALCIUM; CALCIUM SIGNALING; HEART; HUMANS; MUSCLE RELAXATION; MYOCARDIAL CONTRACTION; MYOCARDIUM; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SODIUM; SYMPATHETIC NERVOUS SYSTEM;

EID: 0037049977     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/415198a     Document Type: Review

References (93)

1. Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current and residual β-adrenergic responsiveness
2. Troponin and tropomyosin - Proteins that switch on and tune in the activity of cardiac myofilaments
3. Length dependence of tension generation in rat skinned cardiac muscle
4. Relaxation in rabbit and rat cardiac cells: Species-dependent differences in cellular mechanisms
5. 2+ increases the mitochondrial NADH concentration during elevated work in intact cardiac muscle
6. 2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes
7. Cardiac myocyte calcium transport in phospholamban knockout mouse: Relaxation and endogenous CaMKII effects
8. Alterations of calcium-regulatory proteins in heart failure
9. 2+ buffering in rabbit ventricular myocytes
10. 2+ content after depletion
11. 2--dependent inactivation of L-type calcium channels
12. Calmodulin supports both inactivation and facilitation of L-type calcium channels
13. Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytes
14. 2+ release from sarcoplasmic reticulum in guinea pig ventricular myocytes
15. 2+ release by a local inactivation of ryanodine receptors in cardiac myocytes
16. 2+ channels in rabbit ventricular myocytes during action potential clamp: Influence of temperature
17. Calcium concentration and movement in the diadic cleft space of the cardiac ventricular cell
18. Rapid activation of the cardiac ryanodine receptor by submillisecond calcium stimuli
19. 2+ exchange in inside-out patches excised from guinea-pig ventricular myocytes
20. 2- exchanger by extracellular protons in guinea-pig ventricular myocytes
21. Comparison of subsarcolemmal and bulk calcium concentration during spontaneous calcium release in rat ventricular myocytes
22. Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum
23. Na/Ca exchange current and submembrane [Ca] during cardiac action potential
24. 2+ transient of failing human ventricular myocytes
25. Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes
26. Potentiation of fractional SR Ca release by total and free intra-SR Ca concentration
27. 2-
28. Regulation of calcium release by calcium inside the sarcoplasmic reticulum in ventricular myocytes
29. Phospholamban and cardiac contractile function
30. 2- sensitivity of skeletal and cardiac muscle ryanodine receptors in the presence of calmodulin
31. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
32. Phosphorylation-dependent regulation ofryanodine receptors: A novel role for leucine/isoleucine zippers
33. 2- channels
34. Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor. Proteins of the cardiac junctional sarcoplasmic reticulum membrane
35. 2- release units and couplons in skeletal and cardiac muscles
36. Calcium sparks: Elementary events underlying excitation-contraction coupling in heart muscle
37. 2- sparks, and local control of excitation-contraction coupling in normal heart muscle
38. 2- sparks evoked by action potentials in mouse ventricular myocytes
39. 2- sparks by ruthenium red in permeabilized rat ventricular myocytes
40. The control of calcium release in heart muscle
41. Local calcium transients triggered by single L-type calcium channel currents in cardiac cells
42. 2+ release by a local inactivation of ryanodine receptors in cardiac myocytes
43. 2+ release from the sarcoplasmic reticulum in guinea-pig ventricular myocytes
44. 2- channels can contribute to excitation-contraction coupling in cardiac Purkinje cells
45. Release of calcium from guinea pig cardiac sarcoplasmic reticulum induced by sodium-calcium exchange
46. Sodium current-induced calcium signals in isolated guinea-pig ventricular myocytes
47. 2- exchange
48. Role of sodium-calcium exchange in activation of contraction in rat ventricle
49. 2+ release from the sarcoplasmic reticulum during action potentials in guinea-pig ventricular myocytes
50. Depolarization-induced Ca entry via Na-Ca exchange triggers SR release in guinea pig cardiac myocytes
51. Na-Ca exchange and the trigger for sarcoplasmic reticulum Ca release: Studies in adult rabbit ventricular myocytes
52. 2+ exchange
53. 2- currents in human atrial cells
54. Tetrodotoxin-blockable calcium currents in rat ventricular myocytes: A third type of cardiac cell sodium current
55. + channels: Slip-mode conductance
56. Whether "slip-mode conductance" occurs
57. Whether "slip-mode conductance" occurs
58. 2+-Na-selectivity
59. 2- entry during activation in β-stimulated cardiac myocytes
60. Cardiac excitation-contraction coupling: Role of membrane potential in regulation of contraction
61. 2+ release
62. Identification and functional reconstitution of the type 2 inositol 1,4,5-trisphosphate receptor from ventricular cardiac myocytes
63. Functional InsP-receptors that may modulate excitation-contraction coupling in the heart
64. 3
65. 1-adrenergic, muscarinic, or electrical stimulation in isolated rat heart
66. 1-adrenoceptors that regulate contractile function: Subtypes and subcellular signal transduction mechanisms
67. 2+ and pH homeostasis in rat cardiac myocytes
68. 2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes
69. Theory of excitation-contraction coupling in cardiac muscle
70. 2+ sparks in rat ventricular myocytes
71. Coupled gating between cardiac calcium release channels (ryanodine receptors)
72. 2+ spark frequency in ventricular myocytes
73. Rapid ionic modifications during the aequorin-detected calcium transient in a skinned canine cardiac Purkinje cell
74. 2--release channels
75. New insights into the gating mechanisms of cardiac ryanodine receptors revealed by rapid changes in ligand concentration
76. 2- release in heart
77. 2+ and phosphorylation
78. Phosphorylation of phospholamban and troponin I in β-adrenergic-induced acceleration of cardiac relaxation
79. Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle
80. Protein kinase A phosphorylation of the ryanodine receptor does not alter Ca sparks in permeabilized mouse ventricular myocyte
81. 2+ release cascade by βadrenergic stimulation in rat ventricular myocytes
82. 2+ release during excitation-contraction coupling in cardiac myocytes
83. Isoproterenol does not increase the intrinsic gain of cardiac excitation-contraction coupling (ECC)
84. Integrative analysis of calcium cycling in cardiac muscle
85. 2- channel Caμ 1.2
86. When is cAMP not cAMP? Effects of compartmentalization
87. 2-adrenergic cAMP signaling is uncoupled from phosphorylation of cytoplasmic proteins in canine heart
88. Activated protein kinase C isoforms target to cardiomyocyte cayeolae: Stimulation of local protein phosphorylation
89. Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes
90. 2-adrenergic receptors exhibit differing susceptibility to muscarinic accentuated antagonism