Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation

Journal of Molecular and Cellular Cardiology

Volumn 74, Issue , 2014, Pages 151-161

  Hirt, Marc N ^a,b   Boeddinghaus, Jasper ^a,b   Mitchell, Alice ^c   Schaaf, Sebastian ^a   Börnchen, Christian ^a   Müller, Christian ^a,b   Schulz, Herbert ^b,d   Hubner, Norbert ^b,d   Stenzig, Justus ^a,b   Stoehr, Andrea ^a   Neuber, Christiane ^a,b   Eder, Alexandra ^a,b   Luther, Pradeep K ^c   Hansen, Arne ^a,b   Eschenhagen, Thomas ^a,b  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

2 photon microscopy; Cardiac tissue engineering; Cardiomyocyte maturation; Cardiomyocytes; Electrical stimulation; Induced pluripotent stem cells

Indexed keywords

CALCIUM ION; CONNEXIN 43; BIOLOGICAL MARKER; CALCIUM; ISOPRENALINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ELECTROSTIMULATION; ENGINEERED HEART TISSUE; HEART; HEART BEAT; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RAT; SARCOMERE; TISSUE ENGINEERING; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; HEART CONTRACTION; HEART MUSCLE; METABOLISM; PHYSIOLOGY; PROCEDURES; TISSUE CULTURE TECHNIQUE; ULTRASTRUCTURE;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CALCIUM; CELL DIFFERENTIATION; CELL NUCLEUS; CONNEXIN 43; CYTOPLASM; ELECTRIC STIMULATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; ISOPROTERENOL; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; SARCOMERES; TISSUE CULTURE TECHNIQUES; TISSUE ENGINEERING;

EID: 84904753518     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.05.009     Document Type: Article

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