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Volumn , Issue , 2015, Pages 143-164

Role of the pentose phosphate pathway in tumour metabolism

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EID: 84948744610     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-7091-1824-5_7     Document Type: Chapter
Times cited : (6)

References (113)
  • 1
    • 33845609248 scopus 로고    scopus 로고
    • Irreversible inhibition of glucose-6-phosphate dehydrogenase by the coenzyme A conjugate of ketoprofen: A key to oxidative stress induced by non-steroidal anti-inflammatory drugs?
    • Asensio C, Levoin N, Guillaume C, Guerquin MJ, Rouguieg K, Chretien F, Chapleur Y, Netter P, Minn A, Lapicque F (2007) Irreversible inhibition of glucose-6-phosphate dehydrogenase by the coenzyme A conjugate of ketoprofen: a key to oxidative stress induced by non-steroidal anti-inflammatory drugs? Biochem Pharmacol 73(3): 405-416
    • (2007) Biochem Pharmacol , vol.73 , Issue.3 , pp. 405-416
    • Asensio, C.1    Levoin, N.2    Guillaume, C.3    Guerquin, M.J.4    Rouguieg, K.5    Chretien, F.6    Chapleur, Y.7    Netter, P.8    Minn, A.9    Lapicque, F.10
  • 2
    • 0034654509 scopus 로고    scopus 로고
    • Human glucose-6-phosphate dehydrogenase: The crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency
    • Au SW, Gover S, Lam VM, Adams MJ (2000) Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency. Structure 8(3): 293-303
    • (2000) Structure , vol.8 , Issue.3 , pp. 293-303
    • Au, S.W.1    Gover, S.2    Lam, V.M.3    Adams, M.J.4
  • 4
    • 12644275745 scopus 로고    scopus 로고
    • Glutathione levels and sensitivity to apoptosis are regulated by changes in transaldolase expression
    • Banki K, Hutter E, Colombo E, Gonchoroff NJ, Perl A (1996) Glutathione levels and sensitivity to apoptosis are regulated by changes in transaldolase expression. J Biol Chem 271(51): 32994-33001
    • (1996) J Biol Chem , vol.271 , Issue.51 , pp. 32994-33001
    • Banki, K.1    Hutter, E.2    Colombo, E.3    Gonchoroff, N.J.4    Perl, A.5
  • 5
    • 84895786851 scopus 로고    scopus 로고
    • Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells
    • Baomin L, Iglesias-Pedraz J, Leng-Ying C, Fei Y, Cadenas E, Sita R, Comai L (2014) Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells. Aging Cell 13: 367-378
    • (2014) Aging Cell , vol.13 , pp. 367-378
    • Baomin, L.1    Iglesias-Pedraz, J.2    Leng-Ying, C.3    Fei, Y.4    Cadenas, E.5    Sita, R.6    Comai, L.7
  • 10
    • 0022907590 scopus 로고
    • The value of 6-phosphogluconate dehydrogenase (6-PGDH) activity as a marker of tumour cellularity and prognostic indicator in primary breast cancer
    • Brocklehurst D, Champion AE, Cheek TR, Dewhurst DG (1986) The value of 6-phosphogluconate dehydrogenase (6-PGDH) activity as a marker of tumour cellularity and prognostic indicator in primary breast cancer. Tumour Biol 7(2-3): 99-104
    • (1986) Tumour Biol , vol.7 , Issue.2-3 , pp. 99-104
    • Brocklehurst, D.1    Champion, A.E.2    Cheek, T.R.3    Dewhurst, D.G.4
  • 11
    • 0034855105 scopus 로고    scopus 로고
    • Hypoxia and oxidative stress in breast cancer. Oxidative stress: Its effects on the growth, metastatic potential and response to therapy of breast cancer
    • Brown NS, Bicknell R (2001) Hypoxia and oxidative stress in breast cancer. Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer. Breast Cancer Res 3(5): 323-327
    • (2001) Breast Cancer Res , vol.3 , Issue.5 , pp. 323-327
    • Brown, N.S.1    Bicknell, R.2
  • 12
    • 84877752572 scopus 로고    scopus 로고
    • Stalling the engine of resistance: Targeting cancer metabolism to overcome therapeutic resistance
    • Butler EB, Zhao Y, Munoz-Pinedo C, Lu J, Tan M (2013) Stalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance. Cancer Res 73(9): 2709-2717
    • (2013) Cancer Res , vol.73 , Issue.9 , pp. 2709-2717
    • Butler, E.B.1    Zhao, Y.2    Munoz-Pinedo, C.3    Lu, J.4    Tan, M.5
  • 13
    • 79251517382 scopus 로고    scopus 로고
    • Regulation of cancer cell metabolism
    • Cairns RA, Harris IS, Mak TW (2011) Regulation of cancer cell metabolism. Nat Rev Cancer 11(2): 85-95. doi: 10.1038/nrc2981
    • (2011) Nat Rev Cancer , vol.11 , Issue.2 , pp. 85-95
    • Cairns, R.A.1    Harris, I.S.2    Mak, T.W.3
  • 14
    • 84868019043 scopus 로고    scopus 로고
    • Cancer cell metabolism: One hallmark, many faces
    • Cantor JR, Sabatini DM (2012) Cancer cell metabolism: one hallmark, many faces. Cancer Discov 2(10): 881-898
    • (2012) Cancer Discov , vol.2 , Issue.10 , pp. 881-898
    • Cantor, J.R.1    Sabatini, D.M.2
  • 15
    • 37549026846 scopus 로고    scopus 로고
    • Glucose-6-phosphate dehydrogenase deficiency
    • Cappellini MD, Fiorelli G (2008) Glucose-6-phosphate dehydrogenase deficiency. Lancet 371(9606): 64-74
    • (2008) Lancet , vol.371 , Issue.9606 , pp. 64-74
    • Cappellini, M.D.1    Fiorelli, G.2
  • 18
    • 21244460340 scopus 로고    scopus 로고
    • Mutations in the transketolase-like gene TKTL1: Clinical implications for neurodegenerative diseases, diabetes and cancer
    • Coy JF, Dressler D, Wilde J, Schubert P (2005) Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer. Clin Lab 51(5-6): 257-273
    • (2005) Clin Lab , vol.51 , Issue.5-6 , pp. 257-273
    • Coy, J.F.1    Dressler, D.2    Wilde, J.3    Schubert, P.4
  • 19
    • 84884287630 scopus 로고    scopus 로고
    • 6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met
    • Chan B, VanderLaan PA, Sukhatme VP (2013) 6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met. Biochem Biophys Res Commun 439(2): 247-251
    • (2013) Biochem Biophys Res Commun , vol.439 , Issue.2 , pp. 247-251
    • Chan, B.1    VanderLaan, P.A.2    Sukhatme, V.P.3
  • 21
    • 1242293627 scopus 로고    scopus 로고
    • Glucose-6-phosphate dehydrogenase-deficient cells show an increased propensity for oxidant-induced senescence
    • Cheng ML, Ho HY, Wu YH, Chiu DT (2004) Glucose-6-phosphate dehydrogenase-deficient cells show an increased propensity for oxidant-induced senescence. Free Radic Biol Med 36(5): 580-591
    • (2004) Free Radic Biol Med , vol.36 , Issue.5 , pp. 580-591
    • Cheng, M.L.1    Ho, H.Y.2    Wu, Y.H.3    Chiu, D.T.4
  • 24
    • 79955600638 scopus 로고    scopus 로고
    • Carbon metabolism and the sign of control coefficients in metabolic adaptations underlying K-ras transformation
    • de Atauri P, Benito A, Vizan P, Zanuy M, Mangues R, Marin S, Cascante M (2011) Carbon metabolism and the sign of control coefficients in metabolic adaptations underlying K-ras transformation. Biochim Biophys Acta 1807(6): 746-754
    • (2011) Biochim Biophys Acta , vol.1807 , Issue.6 , pp. 746-754
    • de Atauri, P.1    Benito, A.2    Vizan, P.3    Zanuy, M.4    Mangues, R.5    Marin, S.6    Cascante, M.7
  • 26
    • 80053206983 scopus 로고    scopus 로고
    • Transketolaselike 1 expression is modulated during colorectal cancer progression and metastasis formation
    • Diaz-Moralli S, Tarrado-Castellarnau M, Alenda C, Castells A, Cascante M(2011) Transketolaselike 1 expression is modulated during colorectal cancer progression and metastasis formation. PLoS One 6(9): e25323
    • (2011) PLoS One , vol.6 , Issue.9
    • Diaz-Moralli, S.1    Tarrado-Castellarnau, M.2    Alenda, C.3    Castells, A.4    Cascante, M.5
  • 27
    • 84863628292 scopus 로고    scopus 로고
    • Quantitative analysis of energy metabolic pathways in MCF-7 breast cancer cells by selected reaction monitoring assay
    • Drabovich AP, Pavlou MP, Dimitromanolakis A, Diamandis EP (2012) Quantitative analysis of energy metabolic pathways in MCF-7 breast cancer cells by selected reaction monitoring assay. Mol Cell Proteomics 11: 422-434
    • (2012) Mol Cell Proteomics , vol.11 , pp. 422-434
    • Drabovich, A.P.1    Pavlou, M.P.2    Dimitromanolakis, A.3    Diamandis, E.P.4
  • 28
    • 0016043671 scopus 로고
    • Regulation of the pentose phosphate cycle
    • Eggleston LV, Krebs HA (1974) Regulation of the pentose phosphate cycle. Biochem J 138(3): 425-435
    • (1974) Biochem J , vol.138 , Issue.3 , pp. 425-435
    • Eggleston, L.V.1    Krebs, H.A.2
  • 29
    • 78651010566 scopus 로고
    • Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid
    • Farber S, Diamond LK (1948) Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid. N Engl J Med 238(23): 787-793
    • (1948) N Engl J Med , vol.238 , Issue.23 , pp. 787-793
    • Farber, S.1    Diamond, L.K.2
  • 32
    • 47649120807 scopus 로고    scopus 로고
    • Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver
    • Frederiks WM, Vizan P, Bosch KS, Vreeling-Sindelarova H, Boren J, CascanteM(2008) Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver. Int J Exp Pathol 89(4): 232-240
    • (2008) Int J Exp Pathol , vol.89 , Issue.4 , pp. 232-240
    • Frederiks, W.M.1    Vizan, P.2    Bosch, K.S.3    Vreeling-Sindelarova, H.4    Boren, J.5    Cascante, M.6
  • 33
    • 67650726503 scopus 로고    scopus 로고
    • Ineffective GSH regeneration enhances G6PD-knockdown Hep G2 cell sensitivity to diamide-induced oxidative damage
    • Gao LP, Cheng ML, Chou HJ, Yang YH, Ho HY, Chiu DT (2009) Ineffective GSH regeneration enhances G6PD-knockdown Hep G2 cell sensitivity to diamide-induced oxidative damage. Free Radic Biol Med 47(5): 529-535
    • (2009) Free Radic Biol Med , vol.47 , Issue.5 , pp. 529-535
    • Gao, L.P.1    Cheng, M.L.2    Chou, H.J.3    Yang, Y.H.4    Ho, H.Y.5    Chiu, D.T.6
  • 36
    • 1842530284 scopus 로고    scopus 로고
    • ZNF143 mediates basal and tissue-specific expression of human transaldolase
    • Grossman CE, Qian Y, Banki K, Perl A (2004) ZNF143 mediates basal and tissue-specific expression of human transaldolase. J Biol Chem 279(13): 12190-12205. doi: 10.1074/jbc. M307039200
    • (2004) J Biol Chem , vol.279 , Issue.13 , pp. 12190-12205
    • Grossman, C.E.1    Qian, Y.2    Banki, K.3    Perl, A.4
  • 38
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5): 646-674
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 40
    • 34547105052 scopus 로고    scopus 로고
    • Glucose-6-phosphate dehydrogenase—from oxidative stress to cellular functions and degenerative diseases
    • Ho HY, Cheng ML, Chiu DT (2007) Glucose-6-phosphate dehydrogenase—from oxidative stress to cellular functions and degenerative diseases. Redox Rep 12(3): 109-118
    • (2007) Redox Rep , vol.12 , Issue.3 , pp. 109-118
    • Ho, H.Y.1    Cheng, M.L.2    Chiu, D.T.3
  • 41
    • 0343498281 scopus 로고
    • The mechanism of pentose phosphate conversion to hexose monophosphate. I. With a liver enzyme preparation
    • Horecker BL, Gibbs M, Klenow H, Smyrniotis PZ (1954) The mechanism of pentose phosphate conversion to hexose monophosphate. I. With a liver enzyme preparation. J Biol Chem 207(1): 393-403
    • (1954) J Biol Chem , vol.207 , Issue.1 , pp. 393-403
    • Horecker, B.L.1    Gibbs, M.2    Klenow, H.3    Smyrniotis, P.Z.4
  • 42
    • 34247592022 scopus 로고    scopus 로고
    • The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells
    • Hu LH, Yang JH, Zhang DT, Zhang S, Wang L, Cai PC, Zheng JF, Huang JS (2007) The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells. Anti-Cancer Drugs 18(4): 427-433
    • (2007) Anti-Cancer Drugs , vol.18 , Issue.4 , pp. 427-433
    • Hu, L.H.1    Yang, J.H.2    Zhang, D.T.3    Zhang, S.4    Wang, L.5    Cai, P.C.6    Zheng, J.F.7    Huang, J.S.8
  • 43
    • 22744434002 scopus 로고    scopus 로고
    • Transaldolase is part of a supramolecular complex containing glucose-6-phosphate dehydrogenase in human neutrophils that undergoes retrograde trafficking during pregnancy
    • Huang JB, Espinoza J, Romero R, Petty HR (2005) Transaldolase is part of a supramolecular complex containing glucose-6-phosphate dehydrogenase in human neutrophils that undergoes retrograde trafficking during pregnancy. Metabolism 54(8): 1027-1033
    • (2005) Metabolism , vol.54 , Issue.8 , pp. 1027-1033
    • Huang, J.B.1    Espinoza, J.2    Romero, R.3    Petty, H.R.4
  • 44
    • 84867527044 scopus 로고    scopus 로고
    • Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer
    • Jerby L, Wolf L, Denkert C, Stein GY, Hilvo M, Oresic M, Geiger T, Ruppin E (2012) Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer. Cancer Res 72(22): 5712-5720
    • (2012) Cancer Res , vol.72 , Issue.22 , pp. 5712-5720
    • Jerby, L.1    Wolf, L.2    Denkert, C.3    Stein, G.Y.4    Hilvo, M.5    Oresic, M.6    Geiger, T.7    Ruppin, E.8
  • 45
    • 79952280229 scopus 로고    scopus 로고
    • p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
    • Jiang P, Du W, Wang X, Mancuso A, Gao X, Wu M, Yang X (2011) p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase. Nat Cell Biol 13(3): 310-316. doi: 10.1038/ncb2172
    • (2011) Nat Cell Biol , vol.13 , Issue.3 , pp. 310-316
    • Jiang, P.1    Du, W.2    Wang, X.3    Mancuso, A.4    Gao, X.5    Wu, M.6    Yang, X.7
  • 46
    • 0036832196 scopus 로고    scopus 로고
    • Oxidative stress, DNA damage, and breast cancer
    • Kang DH (2002) Oxidative stress, DNA damage, and breast cancer. AACN Clin Issues 13(4): 540-549
    • (2002) AACN Clin Issues , vol.13 , Issue.4 , pp. 540-549
    • Kang, D.H.1
  • 47
    • 0016245484 scopus 로고
    • Inhibition of glucose 6-phosphate dehydrogenase by palmitoyl coenzyme A
    • Kawaguchi A, Bloch K (1974) Inhibition of glucose 6-phosphate dehydrogenase by palmitoyl coenzyme A. J Biol Chem 249(18): 5793-5800
    • (1974) J Biol Chem , vol.249 , Issue.18 , pp. 5793-5800
    • Kawaguchi, A.1    Bloch, K.2
  • 48
    • 33745489431 scopus 로고    scopus 로고
    • Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
    • Kawanishi S, Hiraku Y, Pinlaor S, Ma N (2006) Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol Chem 387(4): 365-372
    • (2006) Biol Chem , vol.387 , Issue.4 , pp. 365-372
    • Kawanishi, S.1    Hiraku, Y.2    Pinlaor, S.3    Ma, N.4
  • 51
    • 0014205682 scopus 로고
    • Detection of preinvasive and early invasive cancer by 6-phosphogluconate dehydrogenase determinations
    • Kolstad P, Bergsjo P, Koller O, Pihl A, Sanner T (1967) Detection of preinvasive and early invasive cancer by 6-phosphogluconate dehydrogenase determinations. Am J Obstet Gynecol 98(6): 804-807
    • (1967) Am J Obstet Gynecol , vol.98 , Issue.6 , pp. 804-807
    • Kolstad, P.1    Bergsjo, P.2    Koller, O.3    Pihl, A.4    Sanner, T.5
  • 55
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's Achilles' heel
    • Kroemer G, Pouyssegur J (2008) Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 13(6): 472-482
    • (2008) Cancer Cell , vol.13 , Issue.6 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 56
    • 0034107704 scopus 로고    scopus 로고
    • Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice
    • Kuo W, Lin J, Tang TK (2000) Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice. Int J Cancer 85(6): 857-864
    • (2000) Int J Cancer , vol.85 , Issue.6 , pp. 857-864
    • Kuo, W.1    Lin, J.2    Tang, T.K.3
  • 57
    • 0037041277 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 11 in esophageal squamous cell carcinomas
    • Lam CT, Tang CM, Lau KW, Lung ML (2002) Loss of heterozygosity on chromosome 11 in esophageal squamous cell carcinomas. Cancer Lett 178(1): 75-81
    • (2002) Cancer Lett , vol.178 , Issue.1 , pp. 75-81
    • Lam, C.T.1    Tang, C.M.2    Lau, K.W.3    Lung, M.L.4
  • 58
    • 42549156713 scopus 로고    scopus 로고
    • Metastasis is promoted by a bioenergetic switch: New targets for progressive renal cell cancer
    • Langbein S, Frederiks WM, Zur Hausen A, Popa J, Lehmann J, Weiss C, Alken P, Coy JF (2008) Metastasis is promoted by a bioenergetic switch: new targets for progressive renal cell cancer. Int J Cancer 122(11): 2422-2428. doi: 10.1002/ijc.23403
    • (2008) Int J Cancer , vol.122 , Issue.11 , pp. 2422-2428
    • Langbein, S.1    Frederiks, W.M.2    Zur Hausen, A.3    Popa, J.4    Lehmann, J.5    Weiss, C.6    Alken, P.7    Coy, J.F.8
  • 60
    • 84865697252 scopus 로고    scopus 로고
    • Enhanced TKTL1 expression in malignant tumors of the ocular adnexa predicts clinical outcome
    • Jun 1
    • Lange CA, Tisch-Rottensteiner J, Böhringer D, Martin G, Schwartzkopff J, Auw-Haedrich C (2012) Enhanced TKTL1 expression in malignant tumors of the ocular adnexa predicts clinical outcome. Ophthalmology 119(9): 1924-1929. doi: 10.1016/j.ophtha.2012.03.037, Epub 2012 Jun 1
    • (2012) Ophthalmology , vol.119 , Issue.9 , pp. 1924-1929
    • Lange, C.A.1    Tisch-Rottensteiner, J.2    Böhringer, D.3    Martin, G.4    Schwartzkopff, J.5    Auw-Haedrich, C.6
  • 62
    • 60849114962 scopus 로고    scopus 로고
    • A new G6PD knockdown tumorcell line with reduced proliferation and increased susceptibility to oxidative stress
    • Li D, Zhu Y, Tang Q, Lu H, Li H, Yang Y, Li Z, Tong S (2009) A new G6PD knockdown tumorcell line with reduced proliferation and increased susceptibility to oxidative stress. Cancer Biother Radiopharm 24(1): 81-90
    • (2009) Cancer Biother Radiopharm , vol.24 , Issue.1 , pp. 81-90
    • Li, D.1    Zhu, Y.2    Tang, Q.3    Lu, H.4    Li, H.5    Yang, Y.6    Li, Z.7    Tong, S.8
  • 63
    • 0142227019 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
    • Luo J, Manning BD, Cantley LC (2003) Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 4(4): 257-262
    • (2003) Cancer Cell , vol.4 , Issue.4 , pp. 257-262
    • Luo, J.1    Manning, B.D.2    Cantley, L.C.3
  • 64
    • 0035919688 scopus 로고    scopus 로고
    • Malaria. Protecting against bad air
    • Luzzatto L, Notaro R (2001) Malaria. Protecting against bad air. Science 293(5529): 442-443
    • (2001) Science , vol.293 , Issue.5529 , pp. 442-443
    • Luzzatto, L.1    Notaro, R.2
  • 66
    • 84857747903 scopus 로고    scopus 로고
    • Diphenyl urea derivatives as inhibitors of transketolase: A structure-based virtual screening
    • Obiol-Pardo C, Alcarraz-Vizan G, Cascante M, Rubio-Martinez J (2012) Diphenyl urea derivatives as inhibitors of transketolase: a structure-based virtual screening. PLoS One 7(3): e32276
    • (2012) PLoS One , vol.7 , Issue.3
    • Obiol-Pardo, C.1    Alcarraz-Vizan, G.2    Cascante, M.3    Rubio-Martinez, J.4
  • 67
    • 84897130215 scopus 로고    scopus 로고
    • The human condition—a molecular approach
    • Paabo S (2014) The human condition—a molecular approach. Cell 157(1): 216-226
    • (2014) Cell , vol.157 , Issue.1 , pp. 216-226
    • Paabo, S.1
  • 68
    • 0028834278 scopus 로고
    • Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress
    • Pandolfi PP, Sonati F, Rivi R, Mason P, Grosveld F, Luzzatto L (1995) Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress. EMBO J 14(21): 5209-5215
    • (1995) EMBO J , vol.14 , Issue.21 , pp. 5209-5215
    • Pandolfi, P.P.1    Sonati, F.2    Rivi, R.3    Mason, P.4    Grosveld, F.5    Luzzatto, L.6
  • 69
    • 33746879141 scopus 로고    scopus 로고
    • Glycolysis inhibition for anticancer treatment
    • Pelicano H, Martin DS, Xu RH, Huang P (2006) Glycolysis inhibition for anticancer treatment. Oncogene 25(34): 4633-4646
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4633-4646
    • Pelicano, H.1    Martin, D.S.2    Xu, R.H.3    Huang, P.4
  • 70
    • 0033849560 scopus 로고    scopus 로고
    • Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients
    • Portakal O, Ozkaya O, Erden Inal M, Bozan B, Kosan M, Sayek I (2000) Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 33 (4): 279-284
    • (2000) Clin Biochem , vol.33 , Issue.4 , pp. 279-284
    • Portakal, O.1    Ozkaya, O.2    Erden Inal, M.3    Bozan, B.4    Kosan, M.5    Sayek, I.6
  • 75
    • 84867167138 scopus 로고    scopus 로고
    • Glucose-6-phosphate dehydrogenase and NADPH redox regulates cardiac myocyte L-type calcium channel activity and myocardial contractile function
    • Rawat DK, Hecker P, Watanabe M, Chettimada S, Levy RJ, Okada T, Edwards JG, Gupte SA (2012) Glucose-6-phosphate dehydrogenase and NADPH redox regulates cardiac myocyte L-type calcium channel activity and myocardial contractile function. PLoS One 7(10): e45365
    • (2012) PLoS One , vol.7 , Issue.10
    • Rawat, D.K.1    Hecker, P.2    Watanabe, M.3    Chettimada, S.4    Levy, R.J.5    Okada, T.6    Edwards, J.G.7    Gupte, S.A.8
  • 76
    • 84863486244 scopus 로고    scopus 로고
    • The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fate
    • Riganti C, Gazzano E, Polimeni M, Aldieri E, Ghigo D (2012) The pentose phosphate pathway: an antioxidant defense and a crossroad in tumor cell fate. Free Radic Biol Med 53(3): 421-436
    • (2012) Free Radic Biol Med , vol.53 , Issue.3 , pp. 421-436
    • Riganti, C.1    Gazzano, E.2    Polimeni, M.3    Aldieri, E.4    Ghigo, D.5
  • 79
    • 63049112606 scopus 로고    scopus 로고
    • Transaldolase: From biochemistry to human disease
    • Samland AK, Sprenger GA (2009) Transaldolase: from biochemistry to human disease. Int J Biochem Cell Biol 41(7): 1482-1494
    • (2009) Int J Biochem Cell Biol , vol.41 , Issue.7 , pp. 1482-1494
    • Samland, A.K.1    Sprenger, G.A.2
  • 81
    • 84869009687 scopus 로고    scopus 로고
    • How cancer metabolism is tuned for proliferation and vulnerable to disruption
    • Schulze A, Harris AL (2012) How cancer metabolism is tuned for proliferation and vulnerable to disruption. Nature 491(7424): 364-373
    • (2012) Nature , vol.491 , Issue.7424 , pp. 364-373
    • Schulze, A.1    Harris, A.L.2
  • 88
    • 0025851376 scopus 로고
    • Rapid release of bound glucose- 6-phosphate dehydrogenase by growth factors. Correlation with increased enzymatic activity
    • StantonRC, Seifter JL, BoxerDC, Zimmerman E, CantleyLC(1991) Rapid release of bound glucose- 6-phosphate dehydrogenase by growth factors. Correlation with increased enzymatic activity. J Biol Chem 266(19): 12442-12448
    • (1991) J Biol Chem , vol.266 , Issue.19 , pp. 12442-12448
    • Stanton, R.C.1    Seifter, J.L.2    Boxer, D.C.3    Zimmerman, E.4    Cantley, L.C.5
  • 89
    • 84864284168 scopus 로고    scopus 로고
    • Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence
    • Sukhatme VP, Chan B (2012) Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence. FEBS Lett 586(16): 2389-2395
    • (2012) FEBS Lett , vol.586 , Issue.16 , pp. 2389-2395
    • Sukhatme, V.P.1    Chan, B.2
  • 90
    • 76049104247 scopus 로고    scopus 로고
    • TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization
    • 10.1158/1078-0432.CCR-09-2604, Epub2010Jan 26
    • Sun W, Liu Y, Glazer CA, Shao C, Bhan S, Demokan S, Zhao M, Rudek MA, Ha PK, Califano JA (2010) TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization. Clin Cancer Res 16(3): 857-866. doi: 10.1158/1078-0432.CCR-09-2604, Epub 2010 Jan 26
    • (2010) Clin Cancer Res , vol.16 , Issue.3 , pp. 857-866
    • Sun, W.1    Liu, Y.2    Glazer, C.A.3    Shao, C.4    Bhan, S.5    Demokan, S.6    Zhao, M.7    Rudek, M.A.8    Ha, P.K.9    Califano, J.A.10
  • 91
    • 0026021362 scopus 로고
    • Production of large amounts of hydrogen peroxide by human tumor cells
    • Szatrowski TP, Nathan CF (1991) Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 51(3): 794-798
    • (1991) Cancer Res , vol.51 , Issue.3 , pp. 794-798
    • Szatrowski, T.P.1    Nathan, C.F.2
  • 92
    • 0014010261 scopus 로고
    • The effect of palmitoyl coenzyme A on glucose 6-phosphate dehydrogenase and other enzymes
    • Taketa K, Pogell BM (1966) The effect of palmitoyl coenzyme A on glucose 6-phosphate dehydrogenase and other enzymes. J Biol Chem 241(3): 720-726
    • (1966) J Biol Chem , vol.241 , Issue.3 , pp. 720-726
    • Taketa, K.1    Pogell, B.M.2
  • 93
    • 28844478772 scopus 로고    scopus 로고
    • Arachidonic acid inhibits the insulin induction of glucose-6-phosphate dehydrogenase via p38 MAP kinase
    • Talukdar I, Szeszel-Fedorowicz W, Salati LM (2005) Arachidonic acid inhibits the insulin induction of glucose-6-phosphate dehydrogenase via p38 MAP kinase. J Biol Chem 280(49): 40660-40667
    • (2005) J Biol Chem , vol.280 , Issue.49 , pp. 40660-40667
    • Talukdar, I.1    Szeszel-Fedorowicz, W.2    Salati, L.M.3
  • 95
    • 0028229095 scopus 로고
    • Signal transduction proteins that associate with the platelet-derived growth factor (PDGF) receptor mediate the PDGF-induced release of glucose- 6-phosphate dehydrogenase from permeabilized cells
    • Tian WN, Pignatare JN, Stanton RC (1994) Signal transduction proteins that associate with the platelet-derived growth factor (PDGF) receptor mediate the PDGF-induced release of glucose- 6-phosphate dehydrogenase from permeabilized cells. J Biol Chem 269(20): 14798-14805
    • (1994) J Biol Chem , vol.269 , Issue.20 , pp. 14798-14805
    • Tian, W.N.1    Pignatare, J.N.2    Stanton, R.C.3
  • 96
  • 97
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • Trachootham D, Alexandre J, Huang P (2009) Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov 8(7): 579-591
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.7 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 99
    • 80052242132 scopus 로고    scopus 로고
    • Targeting cancer metabolism: A therapeutic window opens
    • Vander Heiden MG (2011) Targeting cancer metabolism: a therapeutic window opens. Nat Rev Drug Discov 10(9): 671-684
    • (2011) Nat Rev Drug Discov , vol.10 , Issue.9 , pp. 671-684
    • Vander Heiden, M.G.1
  • 100
  • 101
    • 36148951374 scopus 로고    scopus 로고
    • Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas
    • Epub 2007 Jul 18
    • Völker HU, Scheich M, Schmausser B, Kämmerer U, Eck M (2007) Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas. Eur Arch Otorhinolaryngol 264(12): 1431-1436, Epub 2007 Jul 18
    • (2007) Eur Arch Otorhinolaryngol , vol.264 , Issue.12 , pp. 1431-1436
    • Völker, H.U.1    Scheich, M.2    Schmausser, B.3    Kämmerer, U.4    Eck, M.5
  • 102
    • 0032511090 scopus 로고    scopus 로고
    • Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidylinositol 3-kinase
    • Wagle A, Jivraj S, Garlock GL, Stapleton SR (1998) Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidylinositol 3-kinase. J Biol Chem 273(24): 14968-14974
    • (1998) J Biol Chem , vol.273 , Issue.24 , pp. 14968-14974
    • Wagle, A.1    Jivraj, S.2    Garlock, G.L.3    Stapleton, S.R.4
  • 103
    • 84866910992 scopus 로고    scopus 로고
    • Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis
    • Wanka C, Steinbach JP, Rieger J (2012) Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis. J Biol Chem 287(40): 33436-33446
    • (2012) J Biol Chem , vol.287 , Issue.40 , pp. 33436-33446
    • Wanka, C.1    Steinbach, J.P.2    Rieger, J.3
  • 104
    • 0000459772 scopus 로고
    • Über den Stoffwechsel der Carcinomzelle
    • Warburg O, Posener K, Negelein E (1924) Über den Stoffwechsel der Carcinomzelle. Biochem Z 152: 309-344
    • (1924) Biochem Z , vol.152 , pp. 309-344
    • Warburg, O.1    Posener, K.2    Negelein, E.3
  • 105
    • 85006768050 scopus 로고
    • The metabolism of tumors in the body
    • Warburg O, Wind F, Negelein E (1927) The metabolism of tumors in the body. J Gen Physiol 8(6): 519-530
    • (1927) J Gen Physiol , vol.8 , Issue.6 , pp. 519-530
    • Warburg, O.1    Wind, F.2    Negelein, E.3
  • 106
    • 84858604270 scopus 로고    scopus 로고
    • Metabolic reprogramming: A cancer hallmark even warburg did not anticipate
    • Ward PS, Thompson CB (2012) Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 21(3): 297-308
    • (2012) Cancer Cell , vol.21 , Issue.3 , pp. 297-308
    • Ward, P.S.1    Thompson, C.B.2
  • 107
    • 60549110886 scopus 로고    scopus 로고
    • Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells
    • Xu X, Zur Hausen A, Coy JF, Löchelt M (2009) Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells. Int J Cancer 124(6): 1330-1337. doi: 10.1002/ijc.24078
    • (2009) Int J Cancer , vol.124 , Issue.6 , pp. 1330-1337
    • Xu, X.1    Zur Hausen, A.2    Coy, J.F.3    Löchelt, M.4
  • 109
    • 79952013435 scopus 로고    scopus 로고
    • Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo
    • Yuan W, Wu S, Guo J, Chen Z, Ge J, Yang P, Hu B (2010) Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo. Cancer Biol Ther 9(9): 710-716
    • (2010) Cancer Biol Ther , vol.9 , Issue.9 , pp. 710-716
    • Yuan, W.1    Wu, S.2    Guo, J.3    Chen, Z.4    Ge, J.5    Yang, P.6    Hu, B.7
  • 111
    • 52049110833 scopus 로고    scopus 로고
    • Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases
    • Zerilli M, Amato MC, Martorana A, Cabibi D, Coy JF, Cappello F, Pompei G, Russo A, Giordano C, Rodolico V (2008) Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases. Cancer 113 (5): 936-944. doi: 10.1002/cncr.23683
    • (2008) Cancer , vol.113 , Issue.5 , pp. 936-944
    • Zerilli, M.1    Amato, M.C.2    Martorana, A.3    Cabibi, D.4    Coy, J.F.5    Cappello, F.6    Pompei, G.7    Russo, A.8    Giordano, C.9    Rodolico, V.10
  • 112
    • 34249905885 scopus 로고    scopus 로고
    • Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells
    • Zhang S, Yang JH, Guo CK, Cai PC (2007) Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells. Cancer Lett 253(1): 108-114
    • (2007) Cancer Lett , vol.253 , Issue.1 , pp. 108-114
    • Zhang, S.1    Yang, J.H.2    Guo, C.K.3    Cai, P.C.4


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