Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo

Cancer Biology and Therapy

Volumn 9, Issue 9, 2010, Pages 710-716

  Yuan, Weijie ^a   Wu, Shaobin ^a   Guo, Jianwu ^a,b   Chen, Zhikang ^a   Ge, Jie ^a   Yang, Pu ^a   Hu, Bin ^a   Chen, Zihua ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Yiyang Central Hospital   (China)

Author keywords

Gastric cancer; siRNA; TKTL1; Tumor proliferation

Indexed keywords

DOUBLE STRANDED RNA; SMALL INTERFERING RNA; TRANSKETOLASE; TRANSKETOLASE LIKE PROTEIN 1; UNCLASSIFIED DRUG; MESSENGER RNA; TKTL1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL FUNCTION; CELL PROLIFERATION; CELL STRAIN AGS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME MECHANISM; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT GENE; MALE; MOUSE; NONHUMAN; STOMACH CANCER; SURVIVAL; UPREGULATION; XENOGRAFT; CANCER CELL; CANCER GROWTH; CELL STRAIN; ENZYME INHIBITION; NUDE MOUSE; PROTEIN EXPRESSION; TUMOR XENOGRAFT; ADENOCARCINOMA; ANIMAL; BAGG ALBINO MOUSE; DRUG ANTAGONISM; DRUG SCREENING; ENZYME IMMUNOASSAY; GENETICS; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH TUMOR; WESTERN BLOTTING;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; GENE SILENCING; HUMANS; IMMUNOENZYME TECHNIQUES; MICE; MICE, INBRED BALB C; MICE, NUDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; STOMACH NEOPLASMS; TRANSKETOLASE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79952013435     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.9.9.11431     Document Type: Article

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