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Volumn 13, Issue , 2013, Pages

A biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cells

Author keywords

Apo10; Biomarker; DNaseX; Early detection and diagnosis; EDIM (epitope detection in monocytes); EDIM blood test; TKTL1

Indexed keywords

APO10 PROTEIN; BIOLOGICAL MARKER; TRANSKETOLASE; TRANSKETOLASE LIKE PROTEIN 1; UNCLASSIFIED DRUG;

EID: 84888799072     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-569     Document Type: Article
Times cited : (51)

References (49)
  • 1
    • 78049260524 scopus 로고    scopus 로고
    • Fit-for-purpose biomarker method validation for application in clinical trials of anticancer drugs
    • 10.1038/sj.bjc.6605910, 2990602, 20924371
    • Cummings J, Raynaud F, Jones L, Sugar R, Dive C. Fit-for-purpose biomarker method validation for application in clinical trials of anticancer drugs. Br J Cancer 2010, 103:1313-1317. 10.1038/sj.bjc.6605910, 2990602, 20924371.
    • (2010) Br J Cancer , vol.103 , pp. 1313-1317
    • Cummings, J.1    Raynaud, F.2    Jones, L.3    Sugar, R.4    Dive, C.5
  • 2
    • 2542468775 scopus 로고    scopus 로고
    • Expression of fatty acid synthase, ErbB2 and Ki-67 in head and neck squamous cell carcinoma. A clinicopathological study
    • 10.1016/j.oraloncology.2004.01.004, 15172638
    • Silva SD, Agostini M, Nishimoto IN, Coletta RD, Alves FA, Lopes MA, Kowalski LP, Graner E. Expression of fatty acid synthase, ErbB2 and Ki-67 in head and neck squamous cell carcinoma. A clinicopathological study. Oral Oncol 2004, 40:688-696. 10.1016/j.oraloncology.2004.01.004, 15172638.
    • (2004) Oral Oncol , vol.40 , pp. 688-696
    • Silva, S.D.1    Agostini, M.2    Nishimoto, I.N.3    Coletta, R.D.4    Alves, F.A.5    Lopes, M.A.6    Kowalski, L.P.7    Graner, E.8
  • 3
    • 0040189824 scopus 로고    scopus 로고
    • Functional characterization of DNase X, a novel endonuclease expressed in muscle cells
    • 10.1021/bi000158w, 10858283
    • Los M, Neubuser D, Coy JF, Mozoluk M, Poustka A, Schulze-Osthoff K. Functional characterization of DNase X, a novel endonuclease expressed in muscle cells. Biochemistry 2000, 39:7365-7373. 10.1021/bi000158w, 10858283.
    • (2000) Biochemistry , vol.39 , pp. 7365-7373
    • Los, M.1    Neubuser, D.2    Coy, J.F.3    Mozoluk, M.4    Poustka, A.5    Schulze-Osthoff, K.6
  • 4
    • 55749095717 scopus 로고    scopus 로고
    • Altered deoxyribonuclease activity in cancer cells and its role in non toxic adjuvant cancer therapy with mixed vitamins C and K3
    • Taper HS. Altered deoxyribonuclease activity in cancer cells and its role in non toxic adjuvant cancer therapy with mixed vitamins C and K3. Anticancer Res 2008, 28:2727-2732.
    • (2008) Anticancer Res , vol.28 , pp. 2727-2732
    • Taper, H.S.1
  • 6
    • 77954248039 scopus 로고    scopus 로고
    • Altered metabolism in cancer
    • 10.1186/1741-7007-8-88, 2892450, 20598111
    • Locasale JW, Cantley LC. Altered metabolism in cancer. BMC Biol 2010, 8:88. 10.1186/1741-7007-8-88, 2892450, 20598111.
    • (2010) BMC Biol , vol.8 , pp. 88
    • Locasale, J.W.1    Cantley, L.C.2
  • 7
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
    • 10.1016/j.cmet.2007.10.002, 18177721
    • DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab 2008, 7:11-20. 10.1016/j.cmet.2007.10.002, 18177721.
    • (2008) Cell Metab , vol.7 , pp. 11-20
    • DeBerardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 8
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • 10.1038/nrc1478, 15516961
    • Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis?. Nat Rev Cancer 2004, 4:891-899. 10.1038/nrc1478, 15516961.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 9
    • 82155171284 scopus 로고    scopus 로고
    • Regulation of reactive oxygen species in stem cells and cancer stem cells
    • 10.1002/jcp.22764, 21448925
    • Kobayashi CI, Suda T. Regulation of reactive oxygen species in stem cells and cancer stem cells. J Cell Physiol 2012, 227:421-430. 10.1002/jcp.22764, 21448925.
    • (2012) J Cell Physiol , vol.227 , pp. 421-430
    • Kobayashi, C.I.1    Suda, T.2
  • 10
    • 84859898559 scopus 로고    scopus 로고
    • Mitochondria and cancer: a growing role in apoptosis, cancer cell metabolism and dedifferentiation
    • 10.1007/978-94-007-2869-1_13, 22399428
    • Scatena R. Mitochondria and cancer: a growing role in apoptosis, cancer cell metabolism and dedifferentiation. Adv Exp Med Biol 2012, 942:287-308. 10.1007/978-94-007-2869-1_13, 22399428.
    • (2012) Adv Exp Med Biol , vol.942 , pp. 287-308
    • Scatena, R.1
  • 11
    • 0029976005 scopus 로고    scopus 로고
    • Molecular cloning of tissue-specific transcripts of a transketolase-related gene: implications for the evolution of new vertebrate genes
    • 10.1006/geno.1996.0124, 8838793
    • Coy JF, Dubel S, Kioschis P, Thomas K, Micklem G, Delius H, Poustka A. Molecular cloning of tissue-specific transcripts of a transketolase-related gene: implications for the evolution of new vertebrate genes. Genomics 1996, 32:309-316. 10.1006/geno.1996.0124, 8838793.
    • (1996) Genomics , vol.32 , pp. 309-316
    • Coy, J.F.1    Dubel, S.2    Kioschis, P.3    Thomas, K.4    Micklem, G.5    Delius, H.6    Poustka, A.7
  • 12
    • 21244460340 scopus 로고    scopus 로고
    • Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer
    • Coy JF, Dressler D, Wilde J, Schubert P. Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer. Clin Lab 2005, 51:257-273.
    • (2005) Clin Lab , vol.51 , pp. 257-273
    • Coy, J.F.1    Dressler, D.2    Wilde, J.3    Schubert, P.4
  • 13
    • 84868525540 scopus 로고    scopus 로고
    • EDIM-TKTL1 blood test: a noninvasive method to detect upregulated glucose metabolism in patients with malignancies
    • 10.2217/fon.12.98, 23130932
    • Feyen O, Coy JF, Prasad V, Schierl R, Saenger J, Baum RP. EDIM-TKTL1 blood test: a noninvasive method to detect upregulated glucose metabolism in patients with malignancies. Future Oncol 2012, 8:1349-1359. 10.2217/fon.12.98, 23130932.
    • (2012) Future Oncol , vol.8 , pp. 1349-1359
    • Feyen, O.1    Coy, J.F.2    Prasad, V.3    Schierl, R.4    Saenger, J.5    Baum, R.P.6
  • 14
    • 34247592022 scopus 로고    scopus 로고
    • The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells
    • 10.1097/CAD.0b013e328013d99e, 17351395
    • Hu LH, Yang JH, Zhang DT, Zhang S, Wang L, Cai PC, Zheng JF, Huang JS. The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells. Anticancer Drugs 2007, 18:427-433. 10.1097/CAD.0b013e328013d99e, 17351395.
    • (2007) Anticancer Drugs , vol.18 , pp. 427-433
    • Hu, L.H.1    Yang, J.H.2    Zhang, D.T.3    Zhang, S.4    Wang, L.5    Cai, P.C.6    Zheng, J.F.7    Huang, J.S.8
  • 15
    • 60549110886 scopus 로고    scopus 로고
    • Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells
    • 10.1002/ijc.24078, 19065656
    • Xu X, Zur Hausen A, Coy JF, Lochelt M. Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells. Int J Cancer 2009, 124:1330-1337. 10.1002/ijc.24078, 19065656.
    • (2009) Int J Cancer , vol.124 , pp. 1330-1337
    • Xu, X.1    Zur Hausen, A.2    Coy, J.F.3    Lochelt, M.4
  • 16
    • 33344456073 scopus 로고    scopus 로고
    • Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted
    • 10.1038/sj.bjc.6602962, 2361175, 16465194
    • Langbein S, Zerilli M, Zur Hausen A, Staiger W, Rensch-Boschert K, Lukan N, Popa J, Ternullo MP, Steidler A, Weiss C, et al. Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted. Br J Cancer 2006, 94:578-585. 10.1038/sj.bjc.6602962, 2361175, 16465194.
    • (2006) Br J Cancer , vol.94 , pp. 578-585
    • Langbein, S.1    Zerilli, M.2    Zur Hausen, A.3    Staiger, W.4    Rensch-Boschert, K.5    Lukan, N.6    Popa, J.7    Ternullo, M.P.8    Steidler, A.9    Weiss, C.10
  • 17
    • 52049110833 scopus 로고    scopus 로고
    • Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases
    • 10.1002/cncr.23683, 18615628
    • Zerilli M, Amato MC, Martorana A, Cabibi D, Coy JF, Cappello F, Pompei G, Russo A, Giordano C, Rodolico V. Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases. Cancer 2008, 113:936-944. 10.1002/cncr.23683, 18615628.
    • (2008) Cancer , vol.113 , pp. 936-944
    • Zerilli, M.1    Amato, M.C.2    Martorana, A.3    Cabibi, D.4    Coy, J.F.5    Cappello, F.6    Pompei, G.7    Russo, A.8    Giordano, C.9    Rodolico, V.10
  • 19
    • 76049104247 scopus 로고    scopus 로고
    • TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization
    • 10.1158/1078-0432.CCR-09-2604, 2824550, 20103683
    • Sun W, Liu Y, Glazer CA, Shao C, Bhan S, Demokan S, Zhao M, Rudek MA, Ha PK, Califano JA. TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization. Clin Cancer Res 2010, 16:857-866. 10.1158/1078-0432.CCR-09-2604, 2824550, 20103683.
    • (2010) Clin Cancer Res , vol.16 , pp. 857-866
    • Sun, W.1    Liu, Y.2    Glazer, C.A.3    Shao, C.4    Bhan, S.5    Demokan, S.6    Zhao, M.7    Rudek, M.A.8    Ha, P.K.9    Califano, J.A.10
  • 20
    • 34249905885 scopus 로고    scopus 로고
    • Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells
    • 10.1016/j.canlet.2007.01.010, 17321041
    • Zhang S, Yang JH, Guo CK, Cai PC. Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells. Cancer Lett 2007, 253:108-114. 10.1016/j.canlet.2007.01.010, 17321041.
    • (2007) Cancer Lett , vol.253 , pp. 108-114
    • Zhang, S.1    Yang, J.H.2    Guo, C.K.3    Cai, P.C.4
  • 21
    • 74049132806 scopus 로고    scopus 로고
    • Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK
    • 10.1007/s00432-009-0652-y, 19655166
    • Schmidt M, Voelker HU, Kapp M, Krockenberger M, Dietl J, Kammerer U. Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK. J Cancer Res Clin Oncol 2010, 136:219-225. 10.1007/s00432-009-0652-y, 19655166.
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 219-225
    • Schmidt, M.1    Voelker, H.U.2    Kapp, M.3    Krockenberger, M.4    Dietl, J.5    Kammerer, U.6
  • 22
    • 79952013435 scopus 로고    scopus 로고
    • Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo
    • 10.4161/cbt.9.9.11431, 20200485
    • Yuan W, Wu S, Guo J, Chen Z, Ge J, Yang P, Hu B. Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo. Cancer Biol Ther 2010, 9:710-716. 10.4161/cbt.9.9.11431, 20200485.
    • (2010) Cancer Biol Ther , vol.9 , pp. 710-716
    • Yuan, W.1    Wu, S.2    Guo, J.3    Chen, Z.4    Ge, J.5    Yang, P.6    Hu, B.7
  • 23
    • 84858208795 scopus 로고    scopus 로고
    • Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression
    • 10.1097/PAT.0b013e32834c352b, 22027741
    • Kayser G, Sienel W, Kubitz B, Mattern D, Stickeler E, Passlick B, Werner M, Zur Hausen A. Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression. Pathology 2011, 43(7):719-724. 10.1097/PAT.0b013e32834c352b, 22027741.
    • (2011) Pathology , vol.43 , Issue.7 , pp. 719-724
    • Kayser, G.1    Sienel, W.2    Kubitz, B.3    Mattern, D.4    Stickeler, E.5    Passlick, B.6    Werner, M.7    Zur Hausen, A.8
  • 24
    • 80051800563 scopus 로고    scopus 로고
    • Expression of transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy
    • 10.1186/1471-2407-11-363, 3176245, 21854597
    • Schwaab J, Horisberger K, Strobel P, Bohn B, Gencer D, Kahler G, Kienle P, Post S, Wenz F, Hofmann WK, et al. Expression of transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy. BMC Cancer 2011, 11:363. 10.1186/1471-2407-11-363, 3176245, 21854597.
    • (2011) BMC Cancer , vol.11 , pp. 363
    • Schwaab, J.1    Horisberger, K.2    Strobel, P.3    Bohn, B.4    Gencer, D.5    Kahler, G.6    Kienle, P.7    Post, S.8    Wenz, F.9    Hofmann, W.K.10
  • 25
    • 80053206983 scopus 로고    scopus 로고
    • Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation
    • 10.1371/journal.pone.0025323, 3181277, 21980427
    • Diaz-Moralli S, Tarrado-Castellarnau M, Alenda C, Castells A, Cascante M. Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation. PLoS One 2011, 6:e25323. 10.1371/journal.pone.0025323, 3181277, 21980427.
    • (2011) PLoS One , vol.6
    • Diaz-Moralli, S.1    Tarrado-Castellarnau, M.2    Alenda, C.3    Castells, A.4    Cascante, M.5
  • 26
    • 48249104383 scopus 로고    scopus 로고
    • Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas
    • 10.1309/6H9844AMMET82DBJ, 18550470
    • Volker HU, Hagemann C, Coy J, Wittig R, Sommer S, Stojic J, Haubitz I, Vince GH, Kammerer U, Monoranu CM. Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas. Am J Clin Pathol 2008, 130:50-57. 10.1309/6H9844AMMET82DBJ, 18550470.
    • (2008) Am J Clin Pathol , vol.130 , pp. 50-57
    • Volker, H.U.1    Hagemann, C.2    Coy, J.3    Wittig, R.4    Sommer, S.5    Stojic, J.6    Haubitz, I.7    Vince, G.H.8    Kammerer, U.9    Monoranu, C.M.10
  • 27
    • 84865697252 scopus 로고    scopus 로고
    • Enhanced TKTL1 expression in malignant tumors of the ocular adnexa predicts clinical outcome
    • 10.1016/j.ophtha.2012.03.037, 22658715
    • Lange CA, Tisch-Rottensteiner J, Bohringer D, Martin G, Schwartzkopff J, Auw-Haedrich C. Enhanced TKTL1 expression in malignant tumors of the ocular adnexa predicts clinical outcome. Ophthalmology 2012, 119:1924-1929. 10.1016/j.ophtha.2012.03.037, 22658715.
    • (2012) Ophthalmology , vol.119 , pp. 1924-1929
    • Lange, C.A.1    Tisch-Rottensteiner, J.2    Bohringer, D.3    Martin, G.4    Schwartzkopff, J.5    Auw-Haedrich, C.6
  • 29
    • 84875945114 scopus 로고    scopus 로고
    • Diagnostic use of epitope detection in monocytes blood test for early detection of colon cancer metastasis
    • 10.2217/fon.13.8, 23560382
    • Jansen N, Coy JF. Diagnostic use of epitope detection in monocytes blood test for early detection of colon cancer metastasis. Future Oncol 2013, 9:605-609. 10.2217/fon.13.8, 23560382.
    • (2013) Future Oncol , vol.9 , pp. 605-609
    • Jansen, N.1    Coy, J.F.2
  • 30
    • 19944368368 scopus 로고    scopus 로고
    • Measurement of intracellular versus extracellular prostate-specific antigen levels in peripheral macrophages: a new approach to noninvasive diagnosis of prostate cancer
    • 10.3816/CGC.2004.n.029, 15636686
    • Herwig R, Pelzer A, Horninger W, Rehder P, Klocker H, Ramoner R, Pinggera GM, Gozzi C, Konwalinka G, Bartsch G. Measurement of intracellular versus extracellular prostate-specific antigen levels in peripheral macrophages: a new approach to noninvasive diagnosis of prostate cancer. Clin Prostate Cancer 2004, 3:184-188. 10.3816/CGC.2004.n.029, 15636686.
    • (2004) Clin Prostate Cancer , vol.3 , pp. 184-188
    • Herwig, R.1    Pelzer, A.2    Horninger, W.3    Rehder, P.4    Klocker, H.5    Ramoner, R.6    Pinggera, G.M.7    Gozzi, C.8    Konwalinka, G.9    Bartsch, G.10
  • 31
    • 42949091931 scopus 로고    scopus 로고
    • Circulating PSA-containing macrophages as a possible target for the detection of prostate cancer: a three-color/five-parameter flow cytometric study on peripheral blood samples
    • 10.1309/THWWRU8L42U5H9PB, 18343793
    • Leers MP, Nap M, Herwig R, Delaere K, Nauwelaers F. Circulating PSA-containing macrophages as a possible target for the detection of prostate cancer: a three-color/five-parameter flow cytometric study on peripheral blood samples. Am J Clin Pathol 2008, 129:649-656. 10.1309/THWWRU8L42U5H9PB, 18343793.
    • (2008) Am J Clin Pathol , vol.129 , pp. 649-656
    • Leers, M.P.1    Nap, M.2    Herwig, R.3    Delaere, K.4    Nauwelaers, F.5
  • 32
    • 77953421610 scopus 로고    scopus 로고
    • Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death
    • 10.1159/000296507, 2956013, 20375558
    • Parihar A, Eubank TD, Doseff AI. Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death. J Innate Immun 2010, 2:204-215. 10.1159/000296507, 2956013, 20375558.
    • (2010) J Innate Immun , vol.2 , pp. 204-215
    • Parihar, A.1    Eubank, T.D.2    Doseff, A.I.3
  • 36
    • 33748752115 scopus 로고    scopus 로고
    • Quantification of immunohistochemistry-issues concerning methods, utility and semiquantitative assessment I
    • 10.1111/j.1365-2559.2006.02514.x, 16978204
    • Walker RA. Quantification of immunohistochemistry-issues concerning methods, utility and semiquantitative assessment I. Histopathology 2006, 49:406-410. 10.1111/j.1365-2559.2006.02514.x, 16978204.
    • (2006) Histopathology , vol.49 , pp. 406-410
    • Walker, R.A.1
  • 37
    • 84859002939 scopus 로고    scopus 로고
    • ImmunoMembrane: a publicly available web application for digital image analysis of HER2 immunohistochemistry
    • 10.1111/j.1365-2559.2011.04142.x, 22296215
    • Tuominen VJ, Tolonen TT, Isola J. ImmunoMembrane: a publicly available web application for digital image analysis of HER2 immunohistochemistry. Histopathology 2012, 60:758-767. 10.1111/j.1365-2559.2011.04142.x, 22296215.
    • (2012) Histopathology , vol.60 , pp. 758-767
    • Tuominen, V.J.1    Tolonen, T.T.2    Isola, J.3
  • 38
    • 78650900647 scopus 로고    scopus 로고
    • ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67
    • 10.1186/bcr2615, 2949645, 20663194
    • Tuominen VJ, Ruotoistenmaki S, Viitanen A, Jumppanen M, Isola J. ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67. Breast Cancer Res 2010, 12:R56. 10.1186/bcr2615, 2949645, 20663194.
    • (2010) Breast Cancer Res , vol.12
    • Tuominen, V.J.1    Ruotoistenmaki, S.2    Viitanen, A.3    Jumppanen, M.4    Isola, J.5
  • 39
    • 0028978505 scopus 로고
    • Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss
    • 10.1002/mc.2940130408, 7646764
    • Edington KG, Loughran OP, Berry IJ, Parkinson EK. Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss. Mol Carcinog 1995, 13:254-265. 10.1002/mc.2940130408, 7646764.
    • (1995) Mol Carcinog , vol.13 , pp. 254-265
    • Edington, K.G.1    Loughran, O.P.2    Berry, I.J.3    Parkinson, E.K.4
  • 40
    • 0019471387 scopus 로고
    • Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas
    • Rheinwald JG, Beckett MA. Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas. Cancer Res 1981, 41:1657-1663.
    • (1981) Cancer Res , vol.41 , pp. 1657-1663
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 41
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958, 75:457-487.
    • (1958) J Am Stat Assoc , vol.75 , pp. 457-487
    • Kaplan, E.L.1    Meier, P.2
  • 42
    • 0013886333 scopus 로고
    • Evaluation of survival data and two new rank order statistics arising in its consideration
    • Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 1966, 50:163-170.
    • (1966) Cancer Chemother Rep , vol.50 , pp. 163-170
    • Mantel, N.1
  • 43
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox DR. Regression models and life tables. J Roy Stat Soc B 1972, 1987-2001.
    • (1972) J Roy Stat Soc B , pp. 1987-2001
    • Cox, D.R.1
  • 44
    • 0027457620 scopus 로고
    • Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine
    • Zweig MH, Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem 1993, 39:561-577.
    • (1993) Clin Chem , vol.39 , pp. 561-577
    • Zweig, M.H.1    Campbell, G.2
  • 45
    • 0034726740 scopus 로고    scopus 로고
    • Characterization of two DNase gamma-specific monoclonal antibodies and the in situ detection of DNase gamma in the nuclei of apoptotic rat thymocytes
    • 10.1006/bbrc.2000.3249, 10964668
    • Shiokawa D, Tanaka M, Kimura T, Hashizume K, Takasawa R, Ohyama H, Fujita K, Yamada T, Tanuma S. Characterization of two DNase gamma-specific monoclonal antibodies and the in situ detection of DNase gamma in the nuclei of apoptotic rat thymocytes. Biochem Biophys Res Commun 2000, 275:343-349. 10.1006/bbrc.2000.3249, 10964668.
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 343-349
    • Shiokawa, D.1    Tanaka, M.2    Kimura, T.3    Hashizume, K.4    Takasawa, R.5    Ohyama, H.6    Fujita, K.7    Yamada, T.8    Tanuma, S.9
  • 46
    • 84866910992 scopus 로고    scopus 로고
    • Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis
    • 10.1074/jbc.M112.384578, 3460445, 22887998
    • Wanka C, Steinbach JP, Rieger J. Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis. J Biol Chem 2012, 287:33436-33446. 10.1074/jbc.M112.384578, 3460445, 22887998.
    • (2012) J Biol Chem , vol.287 , pp. 33436-33446
    • Wanka, C.1    Steinbach, J.P.2    Rieger, J.3
  • 47
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • 10.1016/j.cell.2011.02.013, 21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674. 10.1016/j.cell.2011.02.013, 21376230.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 48
    • 0000459772 scopus 로고
    • Über den Stoffwechsel der Carcinomzelle
    • Warburg O, Posener K, Negolein E. Über den Stoffwechsel der Carcinomzelle. Biochem Z 1924, 309-344.
    • (1924) Biochem Z , pp. 309-344
    • Warburg, O.1    Posener, K.2    Negolein, E.3
  • 49
    • 50949124847 scopus 로고    scopus 로고
    • Human natural killer cells
    • 10.1182/blood-2007-09-077438, 2481557, 18650461
    • Caligiuri MA. Human natural killer cells. Blood 2008, 112:461-469. 10.1182/blood-2007-09-077438, 2481557, 18650461.
    • (2008) Blood , vol.112 , pp. 461-469
    • Caligiuri, M.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.