Transketolase-like protein 1 (TKTL1) Is required for rap and full viability of human tumor cells

International Journal of Cancer

Volumn 124, Issue 6, 2009, Pages 1330-1337

  Xiaojun, Xu ^a   Hansen, Axel Zur ^b   Coy, Johannes F ^c   Löchelt, Martin ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c Darmstadt and Tavargenix GmbH   (Germany)

Author keywords

Aerobic glycolysis; Reactive oxygen species (ROS); ShRNA; TKTL1

Indexed keywords

ISOENZYME; LACTIC ACID; REACTIVE OXYGEN METABOLITE; TRANSKETOLASE; TRANSKETOLASE LIKE PROTEIN 1; TUMOR MARKER; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; GLUCOSE; GLUTATHIONE; MESSENGER RNA; PRIMER DNA; RNA; SMALL INTERFERING RNA; TKTL1 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CANCER CELL CULTURE; CANCER GROWTH; CELL GROWTH; CELL LEVEL; CELL SURVIVAL; CELL VIABILITY; COLON CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME REPRESSION; GENETIC TRANSFECTION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; TUMOR CELL; UPREGULATION; CELL CYCLE; CELL DIVISION; CELL STRAIN HCT116; COLON TUMOR; ENZYMOLOGY; GENETICS; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; COLONIC NEOPLASMS; DNA PRIMERS; GLUCOSE; GLUTATHIONE; HCT116 CELLS; HUMANS; LACTIC ACID; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; RNA, SMALL INTERFERING; TRANSFECTION; TRANSKETOLASE;

EID: 60549110886     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24078     Document Type: Article

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