Ineffective GSH regeneration enhances G6PD-knockdown Hep G2 cell sensitivity to diamide-induced oxidative damage

Free Radical Biology and Medicine

Volumn 47, Issue 5, 2009, Pages 529-535

  Gao, Li Ping ^a   Cheng, Mei Ling ^b,c   Chou, Hsing Jung ^b   Yang, Yu Hsiu ^b   Ho, Hung Yao ^b   Tsun Yee Chiu, Daniel ^b,c  

^a LANZHOU UNIVERSITY   (China)

^b Graduate Institute of Medical Biotechnology   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Cytoskeletal protein; Free radicals; G6PD; Glutathione; Lipid peroxidation; Redox status

Indexed keywords

ACETYLCYSTEINE; CYTOSKELETON PROTEIN; DIAMINE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA;

ARTICLE; CELL DAMAGE; CELL DEATH; CELL PROTECTION; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PEROXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

ANTIOXIDANTS; CELL LINE, TUMOR; CYTOPROTECTION; DIAMIDE; DNA DAMAGE; DRUG RESISTANCE; EFFICIENCY; GENE KNOCKDOWN TECHNIQUES; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUTATHIONE; HUMANS; LIPID PEROXIDATION; OXIDATIVE STRESS; RADIATION-SENSITIZING AGENTS; RNA, SMALL INTERFERING;

EID: 67650726503     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.05.029     Document Type: Article

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