Improving oral drug bioavailability with polycations?

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 97, Issue , 2015, Pages 427-437

  Schulz, Jessica D ^a   Gauthier, Marc A ^b   Leroux, Jean Christophe ^a  

^a ETH ZURICH   (Switzerland)

^b INRS EMT   (Canada)

Author keywords

Chitosan; Macromolecular drug conjugates; Microparticles; Mucoadhesion; Nanoparticles; Oral route; Permeation enhancers; Poly(amidoamine); Poly(lysine); Polycations

Indexed keywords

CHITOSAN; DRUG CARRIER; N TRIMETHYL CHITOSAN; NANOPARTICLE; NUCLEIC ACID; POLYAMIDOAMINE; POLYCATION; POLYLYSINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VACCINE; N-TRIMETHYL CHITOSAN CHLORIDE; POLYAMINE; POLYCATIONS;

BIOCOMPATIBILITY; BIODEGRADABILITY; CYTOTOXICITY; DEGRADATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; GASTROINTESTINAL MUCOSA; GENE THERAPY; HUMAN; INTERNALIZATION; INTESTINE ABSORPTION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; ORAL DRUG ADMINISTRATION; REVIEW; STATIC ELECTRICITY; ANIMAL; BIOAVAILABILITY; CHEMISTRY;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHITOSAN; DRUG DELIVERY SYSTEMS; HUMANS; INTESTINAL ABSORPTION; NANOPARTICLES; POLYAMINES;

EID: 84947940626     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.04.025     Document Type: Review

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