Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery

Journal of Controlled Release

Volumn 56, Issue 1-3, 1998, Pages 259-272

  MacLaughlin, Fiona C ^a   Mumper, Russell J ^c   Wang, Jijun ^a   Tagliaferri, Jenna M ^a   Gill, Inder ^b   Hinchcliffe, Mike ^b   Rolland, Alain P ^a  

^a GeneMedicine Inc   (United States)

^b Danbiosyst UK Ltd   (United Kingdom)

^c Viro Tex Corporation   (United States)

Author keywords

Chitosan; Complexation; DNA plasmid; Endosomolytic peptide; Gene delivery system; Intestinal and colonic gene delivery; Microtitration calorimetry; Non viral gene therapy

Indexed keywords

CHITOSAN; CHLORAMPHENICOL ACETYLTRANSFERASE; LUCIFERASE; OLIGOMER; PLASMID VECTOR; SEACURE 143; SEACURE 243; SEACURE 340; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE TARGETING; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RABBIT; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; ANIMALS; CHEMISTRY, PHYSICAL; CHITIN; CHITOSAN; COLON; COS CELLS; DNA; DRUG STABILITY; FEMALE; GENE TRANSFER TECHNIQUES; GENES, REPORTER; HYDROGEN-ION CONCENTRATION; INTESTINE, SMALL; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PEPTIDES; PLASMIDS; RABBITS; TRANSFECTION;

EID: 0032484162     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00097-2     Document Type: Article

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