Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 22, 2015, Pages 7181-7188

  Maresca, Alfonso ^a   Akyuz, Gulay ^a   Osman, Sameh M ^b   Alothman, Zeid ^b   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Carbonic anhydrase; Isoform selective inhibitor; Phenol; Phenolic acid ester

Indexed keywords

3 HYDROXYPHENETHYL; 4 HYDROXYPHENETHOXYPHENETHYL DERIVATIVE; 4 HYDROXYPHENETHYL; 4''' (4''''' HYDROXYPHENETHOXY)PHENETHYL 3 (3',4' DIHYDROXYPHENYL)ACRYLATE; AMINO ACID; CAFFEIC ACID; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE III; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IV; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE V; CARBONATE DEHYDRATASE VI; CARBONATE DEHYDRATASE VII; CARBONATE DEHYDRATASE VIII; CARBONATE DEHYDRATASE X; CARBONATE DEHYDRATASE XI; CARBONATE DEHYDRATASE XII; CARBONATE DEHYDRATASE XIII; CARBONATE DEHYDRATASE XIV; ESTER DERIVATIVE; FERULIC ACID; PARA COUMARIC ACID; PHENOL DERIVATIVE; PHENOLIC ACID ESTER DERIVATIVE; SULFONAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZINC ION; ESTER; HYDROXYBENZOIC ACID DERIVATIVE; ISOENZYME; PHENOLIC ACID;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVATION; HUMAN; METABOLISM; MOUSE; STRUCTURE ACTIVITY RELATION;

ANIMALS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; ENZYME ACTIVATION; ESTERS; HUMANS; HYDROXYBENZOATES; ISOENZYMES; MICE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84946230608     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2015.10.014     Document Type: Article

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