Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors

Radiotherapy and Oncology

Volumn 83, Issue 3, 2007, Pages 367-373

  Dubois, Ludwig ^a   Douma, Kim ^b   Supuran, Claudiu T ^c   Chiu, Roland K ^a   van Zandvoort, Marc A M J ^b   Pastoreková, Silvia ^d   Scozzafava, Andrea ^c   Wouters, Bradly G ^a   Lambin, Philippe ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF FLORENCE   (Italy)

^d INSTITUTE OF VIROLOGY   (Slovakia)

Author keywords

Carbonic anhydrase IX; Hypoxia; Reoxygenation; Sulfonamide

Indexed keywords

CARBONATE DEHYDRATASE IX; SULFONAMIDE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; HYPOXIA; IMAGING; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; WESTERN BLOTTING;

ANTIGENS, NEOPLASM; BINDING SITES; BINDING, COMPETITIVE; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CATALYSIS; CELL HYPOXIA; CELL LINE, TUMOR; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HUMANS; OXYGEN; SULFONAMIDES;

EID: 34250322126     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2007.04.018     Document Type: Article

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