The η-class carbonic anhydrases as drug targets for antimalarial agents

Expert Opinion on Therapeutic Targets

Volumn 19, Issue 4, 2015, Pages 551-563

  Supuran, Claudiu T ^a   Capasso, Clemente ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b CNR   (Italy)

Author keywords

anion inhibitor; antimalarials; carbonic anhydrase; drug target; sulfonamide; class enzyme

Indexed keywords

ALPHA CARBONIC ANHYDRASE; ANTIMALARIAL AGENT; CARBON DIOXIDE; CARBONATE DEHYDRATASE; DELTA CARBONIC ANHYDRASE; ETA CARBONIC ANHYDRASE; GAMMA CARBONIC ANHYDRASE; GLUTAMIC ACID; HISTIDINE; LEAD; PROTON; SULFONAMIDE; THREONINE; UNCLASSIFIED DRUG; WATER; ZINC ION; CARBONATE DEHYDRATASE INHIBITOR;

CHEMICAL ANALYSIS; DRUG EFFICACY; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME KINETICS; HUMAN; HYDRATION; MALARIA FALCIPARUM; NONHUMAN; PHYLOGENY; PLASMODIUM FALCIPARUM; PROTEIN ANALYSIS; REVIEW; SEQUENCE ANALYSIS; ANIMAL; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; ENZYMOLOGY; MALARIA, FALCIPARUM; MOLECULARLY TARGETED THERAPY; PARASITOLOGY;

ANIMALS; ANTIMALARIALS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; DRUG DESIGN; HUMANS; MALARIA, FALCIPARUM; MOLECULAR TARGETED THERAPY; PHYLOGENY; PLASMODIUM FALCIPARUM;

EID: 84924867437     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2014.991312     Document Type: Review

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