Carbonic anhydrase inhibitors: Water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects

Journal of Medicinal Chemistry

Volumn 43, Issue 25, 2000, Pages 4884-4892

  Casini, A ^a   Scozzafava, A ^a   Mincione, F ^a   Menabuoni, L ^b   Ilies, M A ^c   Supuran, C T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Ospedale San Giovanni di Dio   (Italy)

^c UNIVERSITY OF AGRONOMIC SCIENCES AND VETERINARY MEDICINE OF BUCHAREST   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

4 ISOTHIOCYANATOBENZENESULFONAMIDE; 4 SULFAMOYLPHENYLTHIOUREA; AMINE; AMINO ACID; BETA PHENYLSERINE; CARBONATE DEHYDRATASE INHIBITOR; DOPAMINE; HISTIDINE; ISOENZYME; ISOLEUCINE; LEUCINE; OLIGOPEPTIDE; PHENYLALANINE; PHENYLGLYCINE; SERINE; SERINE DERIVATIVE; THREONINE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; VALINE; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SOLUBILITY; DRUG STRUCTURE; EYE DISEASE; GLAUCOMA; HYDROPHILICITY; INTRAOCULAR PRESSURE; LIPID SOLUBILITY; NONHUMAN; PH; RABBIT; STRUCTURE ACTIVITY RELATION;

EID: 0034649604     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001051+     Document Type: Article

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