-
1
-
-
84863225073
-
Ophthalmic drug discovery: Novel targets and mechanisms for retinal disease and glaucoma
-
Zhang K, Zhang L, Weinreb RN. Ophthalmic drug discovery: novel targets and mechanisms for retinal disease and glaucoma. Nature Rev Drug Discov 2012;11:541-59
-
(2012)
Nature Rev Drug Discov
, vol.11
, pp. 541-559
-
-
Zhang, K.1
Zhang, L.2
Weinreb, R.N.3
-
3
-
-
79954621581
-
Glaucoma
-
Quigley HA. Glaucoma. Lancet 2011;377:1367-77
-
(2011)
Lancet
, vol.377
, pp. 1367-1377
-
-
Quigley, H.A.1
-
4
-
-
33644655886
-
The number of people with glaucoma worldwide in 2010 and 2020
-
Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 2006;90:151-6
-
(2006)
Br J Ophthalmol
, vol.90
, pp. 151-156
-
-
Quigley, H.A.1
Broman, A.T.2
-
5
-
-
2442650952
-
Clinical applications of the carbonic anhydrase inhibitors in ophthalmology
-
Supuran CT Scozzafava A Conway J editors CRC Press, Boca Raton (FL
-
Mincione F, Menabuoni L, Supuran CT. Clinical applications of the carbonic anhydrase inhibitors in ophthalmology. In: Supuran CT, Scozzafava A, Conway J, editors. Carbonic anhydrase-its inhibitors and activators. CRC Press, Boca Raton (FL); 2004 p. 243-54
-
(2004)
Carbonic Anhydrase-its Inhibitors and Activators
, pp. 243-254
-
-
Mincione, F.1
Menabuoni, L.2
Supuran, C.T.3
-
6
-
-
68149088937
-
Antiglaucoma carbonic anhydrase inhibitors as ophthalmologic drugs
-
Supuran CT Winum JY editors Wiley, Hoboken
-
Mincione F, Scozzafava A, Supuran CT. Antiglaucoma carbonic anhydrase inhibitors as ophthalmologic drugs. In: Supuran CT, Winum JY, editors. Drug design of zinc-enzyme inhibitors: functional, structural, and disease applications. Wiley, Hoboken; 2009 p. 139-54
-
(2009)
Drug Design of Zinc-enzyme Inhibitors: Functional Structural and Disease Applications
, pp. 139-154
-
-
Mincione, F.1
Scozzafava, A.2
Supuran, C.T.3
-
8
-
-
84855517237
-
-
WO075152
-
Chong W, Kwan M, Nukui S. 1-[4-(Sulfonyl)-phenyl]-5-benzyl-1H, 1,2,4-triazole derivatives as inhibitors of carbonic anhydrase for treating glaucoma or ocular hypertension. WO075152; 2008
-
(2008)
1-[4-(Sulfonyl)-phenyl]-5-benzyl-1H, 1 2,4-triazole Derivatives As Inhibitors of Carbonic Anhydrase for Treating Glaucoma or Ocular Hypertension
-
-
Chong, W.1
Kwan, M.2
Nukui, S.3
-
28
-
-
0034018870
-
Carbonic anhydrase inhibitors and their therapeutic potential
-
Supuran CT, Scozzafava A. Carbonic anhydrase inhibitors and their therapeutic potential. Expert Opin Ther Pat 2000;10:575-600
-
(2000)
Expert Opin Ther Pat
, vol.10
, pp. 575-600
-
-
Supuran, C.T.1
Scozzafava, A.2
-
29
-
-
38849143765
-
Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators
-
Supuran CT. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nature Rev Drug Discov 2008;7:168-81
-
(2008)
Nature Rev Drug Discov
, vol.7
, pp. 168-181
-
-
Supuran, C.T.1
-
30
-
-
77954218410
-
Carbonic anhydrase inhibitors
-
Supuran CT. Carbonic anhydrase inhibitors. Bioorg Med Chem Lett 2010;20:3467-74
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 3467-3474
-
-
Supuran, C.T.1
-
31
-
-
78649857406
-
Carbonic anhydrase inhibition/activation: Trip of a scientist around the world in the search of novel chemotypes and drug targets
-
Supuran CT. Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets. Curr Pharm Des 2010;16:3233-45
-
(2010)
Curr Pharm des
, vol.16
, pp. 3233-3245
-
-
Supuran, C.T.1
-
33
-
-
84864247302
-
Update on carbonic anhydrase inhibitors: A patent review 2008-2011
-
Aggarwal M, McKenna R. Update on carbonic anhydrase inhibitors: a patent review (2008-2011). Expert Opin Ther Pat 2012;22:903-15
-
(2012)
Expert Opin Ther Pat
, vol.22
, pp. 903-915
-
-
Aggarwal, M.1
McKenna, R.2
-
36
-
-
84863501358
-
Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms?
-
Alterio V, Di Fiore A, D'Ambrosio K, et al. Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms? Chem Rev 2012;112:4421-68
-
(2012)
Chem Rev
, vol.112
, pp. 4421-4468
-
-
Alterio, V.1
Di Fiore, A.2
D'Ambrosio, K.3
-
43
-
-
84865850354
-
Structure-based drug discovery of carbonic anhydrase inhibitors
-
Supuran CT. Structure-based drug discovery of carbonic anhydrase inhibitors. J Enzyme Inhib Med Chem 2012;27:759-72
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 759-772
-
-
Supuran, C.T.1
-
44
-
-
81355149286
-
Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases
-
Bootorabi F, Jänis J, Hytonen VP, et al. Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases. J Enzyme Inhib Med Chem 2011;26:862-70
-
(2011)
J Enzyme Inhib Med Chem
, vol.26
, pp. 862-870
-
-
Bootorabi, F.1
Jänis, J.2
Hytonen, V.P.3
-
45
-
-
84870516777
-
Carbonic anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry
-
Liu F, Martin-Mingot A, Lecornué F, et al. Carbonic anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry. J Enzyme Inhib Med Chem 2012;27:886-91
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 886-891
-
-
Liu, F.1
Martin-Mingot, A.2
Lecornué, F.3
-
46
-
-
84855366173
-
A-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters
-
Cavdar H, Ekinci D, Talaz O, et al. a-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters. J Enzyme Inhib Med Chem 2012;27:148-54
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 148-154
-
-
Cavdar, H.1
Ekinci, D.2
Talaz, O.3
-
47
-
-
84870560662
-
Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity
-
Kazancoglu EA, Güney M, Sentürk M, et al. Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity. J Enzyme Inhib Med Chem 2012;27:880-5
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 880-885
-
-
Kazancoglu, E.A.1
Güney, M.2
Sentürk, M.3
-
48
-
-
84866717865
-
Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI
-
Alp C, Ozsoy S, Alp NA, et al. Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI. J Enzyme Inhib Med Chem 2012;27:818-24
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 818-824
-
-
Alp, C.1
Ozsoy, S.2
Alp, N.A.3
-
49
-
-
84870543839
-
Carbonic anhydrase inhibitors: Inhibition of human and bovine isoenzymes by benzenesulphonamides cyclitols and phenolic compounds
-
Ekinci D, Kurbanoglu NI, Salamc E, et al. Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds. J Enzyme Inhib Med Chem 2012;27:845-8
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 845-848
-
-
Ekinci, D.1
Kurbanoglu, N.I.2
Salamc, E.3
-
50
-
-
84866092055
-
Chromone containing sulfonamides as potent carbonic anhydrase inhibitors
-
Ekinci D, Al-Rashida M, Abbas G, et al. Chromone containing sulfonamides as potent carbonic anhydrase inhibitors. J Enzyme Inhib Med Chem 2012;27:744-7
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 744-747
-
-
Ekinci, D.1
Al-Rashida, M.2
Abbas, G.3
-
51
-
-
84866091339
-
QSARs on human carbonic anhydrase VA and VB inhibitors of some new not yet synthesized, substituted aromatic/heterocyclic sulphonamides as anti-obesity agent
-
Singh S, Supuran CT. QSARs on human carbonic anhydrase VA and VB inhibitors of some new not yet synthesized, substituted aromatic/heterocyclic sulphonamides as anti-obesity agent. J Enzyme Inhib Med Chem 2012;27:666-72
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 666-672
-
-
Singh, S.1
Supuran, C.T.2
-
52
-
-
84870988209
-
DNA cloning, characterization and inhibition studies of an alpha-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae
-
Del Prete S, Isik S, Vullo D, et al. DNA cloning, characterization and inhibition studies of an alpha-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. J Med Chem 2012;55:10742-8
-
(2012)
J Med Chem
, vol.55
, pp. 10742-10748
-
-
Del Prete, S.1
Isik, S.2
Vullo, D.3
-
53
-
-
84870515074
-
Biochemical properties of a novel and highly thermostable bacterial alpha-carbonic anhydrase from Sulfurihydrogenibium yellowstonense YO3AOP
-
Capasso C, De Luca V, Carginale V, et al. Biochemical properties of a novel and highly thermostable bacterial alpha-carbonic anhydrase from Sulfurihydrogenibium yellowstonense YO3AOP. J Enzyme Inhib Med Chem 2012;27:892-7
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 892-897
-
-
Capasso, C.1
De Luca, V.2
Carginale, V.3
-
54
-
-
84865120396
-
Anion inhibition studies of an alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP
-
De Luca V, Vullo D, Scozzafava A, et al. Anion inhibition studies of an alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP. Bioorg Med Chem Lett 2012;22:5630-4
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 5630-5634
-
-
De Luca, V.1
Vullo, D.2
Scozzafava, A.3
-
55
-
-
84866735155
-
The first activation study of a bacterial carbonic anhydrase (CA). The thermostable alpha-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines
-
Vullo D, De Luca V, Scozzafava A, et al. The first activation study of a bacterial carbonic anhydrase (CA). The thermostable alpha-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines. Bioorg Med Chem Lett 2012;22:6324-7
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 6324-6327
-
-
Vullo, D.1
De Luca, V.2
Scozzafava, A.3
-
56
-
-
84869086172
-
Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense
-
Vullo D, De Luca V, Scozzafava A, et al. Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense. Bioorg Med Chem Lett 2012;22:7142-5
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 7142-7145
-
-
Vullo, D.1
De Luca, V.2
Scozzafava, A.3
-
57
-
-
0001795569
-
The formation of the intraocular fluid
-
Friedenwald JS. The formation of the intraocular fluid. Am J Ophthalmol 1949;32:9-27
-
(1949)
Am J Ophthalmol
, vol.32
, pp. 9-27
-
-
Friedenwald, J.S.1
-
58
-
-
0001147656
-
Comparative chemistry of aqueous humor in posterior and anterior chambers of rabbit eye
-
Kinsey VE. Comparative chemistry of aqueous humor in posterior and anterior chambers of rabbit eye. Arch Ophthalmol 1953;50:401-17
-
(1953)
Arch Ophthalmol
, vol.50
, pp. 401-417
-
-
Kinsey, V.E.1
-
59
-
-
0003180272
-
The rate flow of aqueous humor. II. Derivation of rate of flow and its physiologic significance
-
Kinsey VE, Barany E. The rate flow of aqueous humor. II. Derivation of rate of flow and its physiologic significance. Am J Ophthalmol 1949;32:189-202
-
(1949)
Am J Ophthalmol
, vol.32
, pp. 189-202
-
-
Kinsey, V.E.1
Barany, E.2
-
60
-
-
84989992371
-
Carbonic anhydrase in the anterior uvea of the rabbit
-
Wistrand PJ. Carbonic anhydrase in the anterior uvea of the rabbit. Acta Physiol Scand 1951;24:144-8
-
(1951)
Acta Physiol Scand
, vol.24
, pp. 144-148
-
-
Wistrand, P.J.1
-
61
-
-
49749205045
-
The mechanism of the fall in intraocular pressure by the carbonic anhydrase inhibitor Diamox
-
Becker B. The mechanism of the fall in intraocular pressure by the carbonic anhydrase inhibitor Diamox. Am J Ophthalmol 1955;39:177-83
-
(1955)
Am J Ophthalmol
, vol.39
, pp. 177-183
-
-
Becker, B.1
-
62
-
-
0010429778
-
Turnover of total carbon dioxide in aqueous humors and the effect thereon of acetazolamide
-
Kinsey VE, Reddy DVN. Turnover of total carbon dioxide in aqueous humors and the effect thereon of acetazolamide. Arch Ophthalmol 1959;62:78-83
-
(1959)
Arch Ophthalmol
, vol.62
, pp. 78-83
-
-
Kinsey, V.E.1
Reddy, D.V.N.2
-
63
-
-
34249739237
-
The development of topically acting carbonic anhydrase inhibitors as antiglaucoma agents
-
Mincione F, Scozzafava A, Supuran CT. The development of topically acting carbonic anhydrase inhibitors as antiglaucoma agents. Curr Top Med Chem 2007;7:849-54
-
(2007)
Curr Top Med Chem
, vol.7
, pp. 849-854
-
-
Mincione, F.1
Scozzafava, A.2
Supuran, C.T.3
-
64
-
-
0014135426
-
Carbonic anhydrase: Chemistry, physiology and inhibition
-
Maren TH. Carbonic anhydrase: chemistry, physiology and inhibition. Physiol Rev 1967;47:595-781
-
(1967)
Physiol Rev
, vol.47
, pp. 595-781
-
-
Maren, T.H.1
-
65
-
-
0037374846
-
Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: Overexpression of CA12 (CAXII) in glaucoma
-
Liao SY, Ivanov S, Ivanova A, et al. Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma. J Med Genet 2003;40:257-61
-
(2003)
J Med Genet
, vol.40
, pp. 257-261
-
-
Liao, S.Y.1
Ivanov, S.2
Ivanova, A.3
-
66
-
-
0000974035
-
Heterocyclic sulfonamides as carbonic anhydrase inhibitors
-
Miller WH, Dessert AM, Roblin RO. Jr. Heterocyclic sulfonamides as carbonic anhydrase inhibitors. J Am Chem Soc 1950;72:4893-6
-
(1950)
J Am Chem Soc
, vol.72
, pp. 4893-4896
-
-
Miller, W.H.1
Dessert, A.M.2
Roblin Jr., R.O.3
-
67
-
-
5144224910
-
Development of sulfonamide carbonic anhydrase inhibitors (CAIs)
-
Supuran CT, Scozzafava A, Conway J, editors CRC Press, Boca Raton (FL
-
Supuran CT, Scozzafava A, Casini A. Development of sulfonamide carbonic anhydrase inhibitors (CAIs). In: Supuran CT, Scozzafava A, Conway J, editors. Carbonic anhydrase-its inhibitors and activators. CRC Press, Boca Raton (FL); 2004 p. 67-147
-
(2004)
Carbonic Anhydrase-its Inhibitors and Activators
, pp. 67-147
-
-
Supuran, C.T.1
Scozzafava, A.2
Casini, A.3
-
68
-
-
0020630921
-
The transcorneal permeability of sulfonamide carbonic anhydrase inhibitors and their effect on aqueous humor secretion
-
Maren TH, Jankowska L, Sanyal G, et al. The transcorneal permeability of sulfonamide carbonic anhydrase inhibitors and their effect on aqueous humor secretion. Exp Eye Res 1983;36:457-80
-
(1983)
Exp Eye Res
, vol.36
, pp. 457-480
-
-
Maren, T.H.1
Jankowska, L.2
Sanyal, G.3
-
69
-
-
0033990833
-
Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors
-
Sugrue MF. Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors. Progr Ret Eye Res 2000;19:87-112
-
(2000)
Progr Ret Eye Res
, vol.19
, pp. 87-112
-
-
Sugrue, M.F.1
-
70
-
-
0031023338
-
Comparison of dorzolamide and acetazolamide as suppressors of aqueous humor flow in humans
-
Maus TL, Larsson LI, McLaren JW, Brubaker RF. Comparison of dorzolamide and acetazolamide as suppressors of aqueous humor flow in humans. Arch Ophthalmol 1997;115:45-9
-
(1997)
Arch Ophthalmol
, vol.115
, pp. 45-49
-
-
Maus, T.L.1
Larsson, L.I.2
McLaren, J.W.3
Brubaker, R.F.4
-
71
-
-
0034014371
-
Dose-response evaluation of the ocular hypotensive effect of brinzolamide ophthalmic suspension (Azopt
-
Brinzolamide dose-response study group
-
Silver LH. Dose-response evaluation of the ocular hypotensive effect of brinzolamide ophthalmic suspension (Azopt). Brinzolamide dose-response study group. Surv Ophthalmol 2000;44(Suppl 2):147-53
-
(2000)
Surv Ophthalmol
, vol.44
, Issue.SUPPL. 2
, pp. 147-153
-
-
Silver, L.H.1
-
72
-
-
14444286947
-
Contact allergy to dorzolamide eye drops
-
Aalto-Korte K. Contact allergy to dorzolamide eye drops. Contact Dermat 1998;39:206
-
(1998)
Contact Dermat
, vol.39
, pp. 206
-
-
Aalto-Korte, K.1
-
74
-
-
0032693051
-
Anorexia, depression and dementia induced by dorzolamide eye drops (Trusopt
-
Thoe Schwartzenberg GW, Trop GE. Anorexia, depression and dementia induced by dorzolamide eye drops (Trusopt). Can J Ophthalmol 1999;34:93-4
-
(1999)
Can J Ophthalmol
, vol.34
, pp. 93-94
-
-
Thoe Schwartzenberg, G.W.1
Trop, G.E.2
-
75
-
-
0033119461
-
Irreversible corneal decompensation in patients treated with topical dorzolamide
-
Konowal A, Morrison JC, Brown SV, et al. Irreversible corneal decompensation in patients treated with topical dorzolamide. Am J Ophthalmol 1999;127:403-6
-
(1999)
Am J Ophthalmol
, vol.127
, pp. 403-406
-
-
Konowal, A.1
Morrison, J.C.2
Brown, S.V.3
-
76
-
-
0033566151
-
Carbonic anhydrase inhibitors: Synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: Is the tail more important than the ring?
-
Scozzafava A, Menabuoni L, Mincione F, et al. Carbonic anhydrase inhibitors: synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? J Med Chem 1999;42:2641-50
-
(1999)
J Med Chem
, vol.42
, pp. 2641-2650
-
-
Scozzafava, A.1
Menabuoni, L.2
Mincione, F.3
-
77
-
-
0033539043
-
Carbonic anhydrase inhibitors. Synthesis of water-soluble, amino acyl/dipeptidyl sulfonamides possessing long lasting-intraocular pressure lowering properties via the topical route
-
Scozzafava A, Briganti F, Mincione G, et al. Carbonic anhydrase inhibitors. Synthesis of water-soluble, amino acyl/dipeptidyl sulfonamides possessing long lasting-intraocular pressure lowering properties via the topical route. J Med Chem 1999;42:3690-700
-
(1999)
J Med Chem
, vol.42
, pp. 3690-3700
-
-
Scozzafava, A.1
Briganti, F.2
Mincione, G.3
-
78
-
-
0034676310
-
Carbonic anhydrase inhibitors: Perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure lowering agents with prolonged duration of action
-
Scozzafava A, Menabuoni L, Mincione F, et al. Carbonic anhydrase inhibitors: perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure lowering agents with prolonged duration of action. J Med Chem 2000;43:4542-51
-
(2000)
J Med Chem
, vol.43
, pp. 4542-4551
-
-
Scozzafava, A.1
Menabuoni, L.2
Mincione, F.3
-
79
-
-
0037187391
-
Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long lasting, topical intraocular pressure lowering properties
-
Scozzafava A, Menabuoni L, Mincione F, et al. Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long lasting, topical intraocular pressure lowering properties. J Med Chem 2002;45:1466-76
-
(2002)
J Med Chem
, vol.45
, pp. 1466-1476
-
-
Scozzafava, A.1
Menabuoni, L.2
Mincione, F.3
-
80
-
-
65349159298
-
Synthesis of novel nitric oxide (NO)-releasing esters of timolol
-
Chiroli V, Batugo MR, Biondi S, et al. Synthesis of novel nitric oxide (NO)-releasing esters of timolol. Bioorg Med Chem Lett 2009;19:2785-8
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 2785-2788
-
-
Chiroli, V.1
Batugo, M.R.2
Biondi, S.3
-
81
-
-
71749104748
-
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma
-
Steele RM, Batugo MR, Benedini F, et al. Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma. Bioorg Med Chem Lett 2009;19:6565-70 .
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 6565-6570
-
-
Steele, R.M.1
Batugo, M.R.2
Benedini, F.3
-
82
-
-
79956062824
-
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action
-
Mincione F, Benedini F, Biondi S, et al. Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action. Bioorg Med Chem Lett 2011;21:3216-21
-
(2011)
Bioorg Med Chem Lett
, vol.21
, pp. 3216-3221
-
-
Mincione, F.1
Benedini, F.2
Biondi, S.3
-
83
-
-
84855408335
-
A new approach to antiglaucoma drugs: Carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology
-
Fabrizi F, Mincione F, Somma T, et al. A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology. J Enzyme Inhib Med Chem 2012;27:138-47
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 138-147
-
-
Fabrizi, F.1
Mincione, F.2
Somma, T.3
-
87
-
-
84872915972
-
A Multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma
-
Long DD, Frieman B, Hegde SS, et al. A Multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma. Bioorg Med Chem Lett 2013;23:939-43
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 939-943
-
-
Long, D.D.1
Frieman, B.2
Hegde, S.S.3
-
88
-
-
79961070760
-
Carbonic anhydrase inhibitors and activators for novel therapeutic applications
-
Supuran CT. Carbonic anhydrase inhibitors and activators for novel therapeutic applications. Future Med Chem 2011;3:1165-80
-
(2011)
Future Med Chem
, vol.3
, pp. 1165-1180
-
-
Supuran, C.T.1
-
93
-
-
84872209688
-
-
WO016288
-
Matulis D, Dudutiene V, Matuliene J, et al. Benzimidazo[1,2-c][1,2,3] thiadiazol-7-sulfonamides as inhibitors of carbonic anhydrase and the intermediates for production thereof. WO016288; 2008
-
(2008)
Benzimidazo[1,2-c][1,2,3] thiadiazol-7-sulfonamides As Inhibitors of Carbonic Anhydrase and the Intermediates for Production Thereof
-
-
Matulis, D.1
Dudutiene, V.2
Matuliene, J.3
-
94
-
-
77958022642
-
Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c] [1,2,3] thiadiazole-7-sulphonamides
-
Baranauskiene L, Hilvo M, Matuliene J, et al. Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c] [1,2,3] thiadiazole-7-sulphonamides. J Enzyme Inhib Med Chem 2010;25:863-70
-
(2010)
J Enzyme Inhib Med Chem
, vol.25
, pp. 863-870
-
-
Baranauskiene, L.1
Hilvo, M.2
Matuliene, J.3
-
99
-
-
77955391402
-
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule
-
Carta F, Temperini C, Innocenti A, et al. Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. J Med Chem 2010;53:5511-22
-
(2010)
J Med Chem
, vol.53
, pp. 5511-5522
-
-
Carta, F.1
Temperini, C.2
Innocenti, A.3
-
100
-
-
67749116253
-
Non-zinc mediated inhibition of carbonic anhydrases: Coumarins are a new class of suicide inhibitors
-
Maresca A, Temperini C, Vu H, et al. Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors. J Am Chem Soc 2009;131:3057-62
-
(2009)
J Am Chem Soc
, vol.131
, pp. 3057-3062
-
-
Maresca, A.1
Temperini, C.2
Vu, H.3
-
101
-
-
74849118851
-
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins
-
Maresca A, Temperini C, Pochet L, et al. Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J Med Chem 2010;53:335-44
-
(2010)
J Med Chem
, vol.53
, pp. 335-344
-
-
Maresca, A.1
Temperini, C.2
Pochet, L.3
-
102
-
-
84055176334
-
Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors
-
Touisni N, Maresca A, McDonald PC, et al. Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors. J Med Chem 2011;54:8271-7
-
(2011)
J Med Chem
, vol.54
, pp. 8271-8277
-
-
Touisni, N.1
Maresca, A.2
McDonald, P.C.3
-
103
-
-
84855702121
-
Dithiocarbamates: A new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations
-
Carta F, Aggarwal M, Maresca A, et al. Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. Chem Commun (Cambridge) 2012;48:1868-70
-
(2012)
Chem Commun (Cambridge
, vol.48
, pp. 1868-1870
-
-
Carta, F.1
Aggarwal, M.2
Maresca, A.3
-
104
-
-
84857420193
-
Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo
-
Carta F, Aggarwal M, Maresca A, et al. Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo. J Med Chem 2012;55:1721-30
-
(2012)
J Med Chem
, vol.55
, pp. 1721-1730
-
-
Carta, F.1
Aggarwal, M.2
Maresca, A.3
-
105
-
-
84855658697
-
Dithiocarbamates strongly inhibit the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata
-
Monti SM, Maresca A, Viparelli F, et al. Dithiocarbamates strongly inhibit the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata. Bioorg Med Chem Lett 2012;22:859-62
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 859-862
-
-
Monti, S.M.1
Maresca, A.2
Viparelli, F.3
-
106
-
-
84874604544
-
Dithiocarbamates strongly inhibit the beta-class carbonic anhydrases from Mycobacterium tuberculosis
-
Maresca A, Carta F, Vullo D, Supuran CT. Dithiocarbamates strongly inhibit the beta-class carbonic anhydrases from Mycobacterium tuberculosis. J Enzyme Inhib Med Chem 2013;28:407-11
-
(2013)
J Enzyme Inhib Med Chem
, vol.28
, pp. 407-411
-
-
Maresca, A.1
Carta, F.2
Vullo, D.3
Supuran, C.T.4
-
107
-
-
72249106865
-
Carbonic anhydrase inhibitors. X-Ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct-an inhibitor mimicking the sulfonamide and urea binding to the enzyme
-
Temperini C, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. X-Ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct-an inhibitor mimicking the sulfonamide and urea binding to the enzyme. Bioorg Med Chem Lett 2010;20:474-8
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 474-478
-
-
Temperini, C.1
Scozzafava, A.2
Supuran, C.T.3
-
108
-
-
79953317071
-
1alpha25(OH)2-3-Epi-Vitamin D3 a natural physiological metabolite of vitamin D3: Its synthesis biological activity and crystal structure with its receptor
-
Molnar F, Siguero R, Sato Y, et al. 1alpha,25(OH)2-3-Epi-Vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor. PLoS One 2011;6:e18124
-
(2011)
PLoS One
, vol.6
-
-
Molnar, F.1
Siguero, R.2
Sato, Y.3
-
109
-
-
84856083583
-
1alpha,25-Dihydroxyvitamin D3 and its analog, 2-methylene-19-nor (20S)-1a,25-dihydroxyvitamin D3 (2MD), suppress intraocular pressure in non-human primates
-
Kutuzova G, Gabelt BAT, Kiland JA, et al. 1alpha,25-Dihydroxyvitamin D3 and its analog, 2-methylene-19-nor (20S)-1a,25-dihydroxyvitamin D3 (2MD), suppress intraocular pressure in non-human primates. Arch Biochem Biophys 2012;518:53-60
-
(2012)
Arch Biochem Biophys
, vol.518
, pp. 53-60
-
-
Kutuzova, G.1
Gabelt, B.A.T.2
Kiland, J.A.3
|