Carbonic anhydrase activators: l-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 3, 2007, Pages 628-635

  Temperini, Claudia ^a   Innocenti, Alessio ^a   Scozzafava, Andrea ^a   Mastrolorenzo, Antonio ^a   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase; Enzyme activator; Histamine; l Adrenaline; X ray crystallography

Indexed keywords

ADRENALIN; CARBONATE DEHYDRATASE; HISTAMINE; ISOENZYME;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CARBONIC ANHYDRASES; CRYSTALLOGRAPHY, X-RAY; CYTOSOL; ENZYME ACTIVATORS; EPINEPHRINE; HISTAMINE; ISOENZYMES; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION;

EID: 33846283799     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.11.027     Document Type: Article

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