An overview of the selectivity and efficiency of the bacterial carbonic anhydrase inhibitors

Current Medicinal Chemistry

Volumn 22, Issue 18, 2015, Pages 2130-2139

  Capasso, C ^a   Supuran, C T ^b  

^a CNR   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Anions; Antibacterial; Antiinfective; CA inhibitors; Carbonic anhydrase; Hydratase activity; Pathogens; Selective inhibition; Sulfonamide; X ray

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL ENZYME; CARBON DIOXIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; ISOPROTEIN; LIGAND; SULFONAMIDE; ZINC; ANTIINFECTIVE AGENT;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; DRUG DESIGN; DRUG SELECTIVITY; ENZYME ACTIVE SITE; ENZYME MECHANISM; HELICOBACTER PYLORI; HUMAN; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PORPHYROMONAS GINGIVALIS; PRODUCTIVITY; VIBRIO CHOLERAE; BACTERIUM; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BACTERIA; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; DOSE-RESPONSE RELATIONSHIP, DRUG; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84934344324     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867321666141012174921     Document Type: Article

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