Carbonic anhydrase inhibitors - Part 29: Interaction of isozymes I, II and IV with benzolamide-like derivatives

European Journal of Medicinal Chemistry

Volumn 33, Issue 9, 1998, Pages 739-751

  Supuran, Claudiu T ^a   Ilies, Marc A ^b   Scozzafava, Andrea ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF BUCHAREST   (Romania)

Author keywords

Aromatic nucleophilic substitution; Carbonic anhydrase; Heterocyclic sulfonamides; Inhibitors; Isozymes I, II, IV; Positron emission tomography (PET); Positron emitting isotopes

Indexed keywords

1 [5 SULFAMOYL 1,3,4 THIADIAZOL 2 YL (AMINOSULFONYL 4 PHENYL)] 2,4,6 TRIMETHYLPYRIDINIUM PERCHLORATE; 1 [5 SULFAMOYL 1,3,4 THIADIAZOL 2 YL (AMINOSULFONYL 4 PHENYL)] 2,4,6 TRIPHENHYLPYRIDINIUM TETRAFLUOROBORONATE; 5 (2 CARBOXYBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (2 NITROBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (2,4 DINITROBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (2,4,6 TRIMETHYLBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (3 AMINOBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (3 NITROBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 ACETYLAMINOBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 AMINOBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 BROMOBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 CHLORO 3 NITROBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 CHLOROBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 FLUOROBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 IODOBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 METHOXYBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 METHYLBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (4 NITROBENZENESULFONAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 (N,N DIMETHYLAMINOSULFAMOYL) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 METHYLSULFONAMIDO 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 PHENYLMETHYLSULFONAMIDO 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 SULFONYLAMINO 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 SULFONYLIMINO 4 METHYL 2 SULFONAMIDO DELTA2 1,3,4 THIADIAZOLINE DERIVATIVE; ACETAZOLAMIDE; BENZOLAMIDE; CARBONATE DEHYDRATASE INHIBITOR; CONTRAST MEDIUM; ETHOXZOLAMIDE; METHAZOLAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; DRUG SELECTIVITY; DRUG SOLUBILITY; DRUG SYNTHESIS; ENZYME INHIBITION; IONIZATION; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; POSITRON EMISSION TOMOGRAPHY; REACTION ANALYSIS; RECEPTOR AFFINITY;

EID: 0032433303     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(98)80042-1     Document Type: Article

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