메뉴 건너뛰기




Volumn 132, Issue , 2015, Pages 151-188

Trafficking of β-adrenergic receptors: Implications in intracellular receptor signaling

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; BETA ARRESTIN 2; CAVEOLIN; CAVEOLIN 3; CLATHRIN; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; BETA ARRESTIN; LIGAND; PROTEIN BINDING; RETINA S ANTIGEN;

EID: 84946176992     PISSN: 18771173     EISSN: 18780814     Source Type: Book Series    
DOI: 10.1016/bs.pmbts.2015.03.008     Document Type: Conference Paper
Times cited : (21)

References (173)
  • 2
    • 0038581576 scopus 로고    scopus 로고
    • Myocyte adrenoceptor signaling pathways
    • Xiang Y, Kobilka BK. Myocyte adrenoceptor signaling pathways. Science. 2003; 300(5625):1530-1532.
    • (2003) Science , vol.300 , Issue.5625 , pp. 1530-1532
    • Xiang, Y.1    Kobilka, B.K.2
  • 3
    • 33744900324 scopus 로고    scopus 로고
    • Subtype-specific alpha1-and beta-adrenoceptor signaling in the heart
    • Xiao RP, Zhu W, Zheng M, et al. Subtype-specific alpha1-and beta-adrenoceptor signaling in the heart. Trends Pharmacol Sci. 2006;27(6):330-337.
    • (2006) Trends Pharmacol Sci , vol.27 , Issue.6 , pp. 330-337
    • Xiao, R.P.1    Zhu, W.2    Zheng, M.3
  • 4
    • 0023645178 scopus 로고
    • Purification and characterization of the beta-adrenergic receptor kinase
    • Benovic JL, Mayor Jr F, Staniszewski C, Lefkowitz RJ, Caron MG. Purification and characterization of the beta-adrenergic receptor kinase. J Biol Chem. 1987; 262(19):9026-9032.
    • (1987) J Biol Chem , vol.262 , Issue.19 , pp. 9026-9032
    • Benovic, J.L.1    Mayor, F.2    Staniszewski, C.3    Lefkowitz, R.J.4    Caron, M.G.5
  • 6
    • 0025352299 scopus 로고
    • Beta-Arrestin: A protein that regulates beta-adrenergic receptor function
    • Lohse MJ, Benovic JL, Codina J, Caron MG, Lefkowitz RJ. beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science. 1990;248(4962):1547-1550.
    • (1990) Science , vol.248 , Issue.4962 , pp. 1547-1550
    • Lohse, M.J.1    Benovic, J.L.2    Codina, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 7
    • 0037036135 scopus 로고    scopus 로고
    • A role for lipid shells in targeting proteins to caveolae, rafts, and other lipid domains
    • Anderson RG, Jacobson K. A role for lipid shells in targeting proteins to caveolae, rafts, and other lipid domains. Science. 2002;296(5574):1821-1825.
    • (2002) Science , vol.296 , Issue.5574 , pp. 1821-1825
    • Anderson, R.G.1    Jacobson, K.2
  • 8
    • 0037131192 scopus 로고    scopus 로고
    • Regulation ofGprotein-coupled receptor signaling by scaffold proteins
    • Hall RA, Lefkowitz RJ. Regulation ofGprotein-coupled receptor signaling by scaffold proteins. Circ Res. 2002;91(8):672-680.
    • (2002) Circ Res , vol.91 , Issue.8 , pp. 672-680
    • Hall, R.A.1    Lefkowitz, R.J.2
  • 9
    • 0034623942 scopus 로고    scopus 로고
    • Beta 1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of beta 1-adrenergic receptor interaction with N-methyl-D-aspartate receptors
    • Hu LA, Tang Y, Miller WE, et al. beta 1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of beta 1-adrenergic receptor interaction with N-methyl-D-aspartate receptors. J Biol Chem. 2000;275(49):38659-38666.
    • (2000) J Biol Chem , vol.275 , Issue.49 , pp. 38659-38666
    • Hu, L.A.1    Tang, Y.2    Miller, W.E.3
  • 10
    • 0033535942 scopus 로고    scopus 로고
    • Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice
    • Engelhardt S, Hein L, Wiesmann F, Lohse MJ. Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proc Natl Acad Sci USA. 1999;96(12):7059-7064.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.12 , pp. 7059-7064
    • Engelhardt, S.1    Hein, L.2    Wiesmann, F.3    Lohse, M.J.4
  • 11
    • 0032729995 scopus 로고    scopus 로고
    • Opposing effects of beta(1)-and beta 2)-adrenergic receptors on cardiac myocyte apoptosis: Role of a pertussis toxinsensitive G protein
    • Communal C, Singh K, Sawyer DB, Colucci WS. Opposing effects of beta(1)-and beta(2)-adrenergic receptors on cardiac myocyte apoptosis: role of a pertussis toxinsensitive G protein. Circulation. 1999;100(22):2210-2212.
    • (1999) Circulation , vol.100 , Issue.22 , pp. 2210-2212
    • Communal, C.1    Singh, K.2    Sawyer, D.B.3    Colucci, W.S.4
  • 12
    • 0035852634 scopus 로고    scopus 로고
    • Dual modulation of cell survival and cell death by beta 2)-adrenergic signaling in adult mouse cardiac myocytes
    • Zhu WZ, Zheng M, Koch WJ, Lefkowitz RJ, Kobilka BK, Xiao RP. Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes. Proc Natl Acad Sci USA. 2001;98(4):1607-1612.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.4 , pp. 1607-1612
    • Zhu, W.Z.1    Zheng, M.2    Koch, W.J.3    Lefkowitz, R.J.4    Kobilka, B.K.5    Xiao, R.P.6
  • 13
    • 33749665081 scopus 로고    scopus 로고
    • Compartmentation of cyclic nucleotide signaling in the heart: The role of cyclic nucleotide phosphodiesterases
    • Fischmeister R, Castro LR, Abi-Gerges A, et al. Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases. Circ Res. 2006;99(8):816-828.
    • (2006) Circ Res , vol.99 , Issue.8 , pp. 816-828
    • Fischmeister, R.1    Castro, L.R.2    Abi-Gerges, A.3
  • 14
    • 33750910207 scopus 로고    scopus 로고
    • Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling
    • Nikolaev VO, Bunemann M, Schmitteckert E, Lohse MJ, Engelhardt S. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling. Circ Res. 2006;99(10):1084-1091.
    • (2006) Circ Res , vol.99 , Issue.10 , pp. 1084-1091
    • Nikolaev, V.O.1    Bunemann, M.2    Schmitteckert, E.3    Lohse, M.J.4    Engelhardt, S.5
  • 15
    • 23744497054 scopus 로고    scopus 로고
    • Caveolae and lipid rafts: G protein-coupled receptor signaling microdomains in cardiac myocytes
    • Insel PA, Head BP, Ostrom RS, et al. Caveolae and lipid rafts: G protein-coupled receptor signaling microdomains in cardiac myocytes. Ann NY Acad Sci. 2005;1047:166-172.
    • (2005) Ann NY Acad Sci , vol.1047 , pp. 166-172
    • Insel, P.A.1    Head, B.P.2    Ostrom, R.S.3
  • 16
    • 0034009080 scopus 로고    scopus 로고
    • Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions
    • Soderling SH, Beavo JA. Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. Curr Opin Cell Biol. 2000;12(2):174-179.
    • (2000) Curr Opin Cell Biol , vol.12 , Issue.2 , pp. 174-179
    • Soderling, S.H.1    Beavo, J.A.2
  • 17
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
    • Okamoto T, Schlegel A, Scherer PE, Lisanti MP. Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J Biol Chem. 1998;273(10):5419-5422.
    • (1998) J Biol Chem , vol.273 , Issue.10 , pp. 5419-5422
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 18
    • 0035943423 scopus 로고    scopus 로고
    • Emerging themes in lipid rafts and caveolae
    • Galbiati F, Razani B, Lisanti MP. Emerging themes in lipid rafts and caveolae. Cell. 2001;106(4):403-411.
    • (2001) Cell , vol.106 , Issue.4 , pp. 403-411
    • Galbiati, F.1    Razani, B.2    Lisanti, M.P.3
  • 19
    • 4644224284 scopus 로고    scopus 로고
    • Role of caveolae and caveolins in health and disease
    • Cohen AW, Hnasko R, Schubert W, Lisanti MP. Role of caveolae and caveolins in health and disease. Physiol Rev. 2004;84(4):1341-1379.
    • (2004) Physiol Rev , vol.84 , Issue.4 , pp. 1341-1379
    • Cohen, A.W.1    Hnasko, R.2    Schubert, W.3    Lisanti, M.P.4
  • 20
    • 0034731376 scopus 로고    scopus 로고
    • Differential targeting of beta-adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway
    • Rybin VO, Xu X, Lisanti MP, Steinberg SF. Differential targeting of beta-adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway. J Biol Chem. 2000; 275(52):41447-41457.
    • (2000) J Biol Chem , vol.275 , Issue.52 , pp. 41447-41457
    • Rybin, V.O.1    Xu, X.2    Lisanti, M.P.3    Steinberg, S.F.4
  • 21
    • 0037072884 scopus 로고    scopus 로고
    • Caveolar localization dictates physiologic signaling of beta 2-adrenoceptors in neonatal cardiac myocytes
    • Xiang Y, Rybin VO, Steinberg SF, Kobilka B. Caveolar localization dictates physiologic signaling of beta 2-adrenoceptors in neonatal cardiac myocytes. J Biol Chem. 2002;277(37):34280-34286.
    • (2002) J Biol Chem , vol.277 , Issue.37 , pp. 34280-34286
    • Xiang, Y.1    Rybin, V.O.2    Steinberg, S.F.3    Kobilka, B.4
  • 22
    • 34147137118 scopus 로고    scopus 로고
    • Seven transmembrane receptors: Something old, something new
    • Lefkowitz RJ. Seven transmembrane receptors: something old, something new. Acta Physiol (Oxf ). 2007;190(1):9-19.
    • (2007) Acta Physiol (Oxf ) , vol.190 , Issue.1 , pp. 9-19
    • Lefkowitz, R.J.1
  • 23
    • 0030613761 scopus 로고    scopus 로고
    • Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A
    • Daaka Y, Luttrell LM, Lefkowitz RJ. Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature. 1997;390(6655):88-91.
    • (1997) Nature , vol.390 , Issue.6655 , pp. 88-91
    • Daaka, Y.1    Luttrell, L.M.2    Lefkowitz, R.J.3
  • 24
    • 70450231632 scopus 로고    scopus 로고
    • Agonist dose-dependent phosphorylation by protein kinase A and G protein-coupled receptor kinase regulates beta2 adrenoceptor coupling to G i) proteins in cardiomyocytes
    • Liu R, Ramani B, Soto D, De Arcangelis V, Xiang Y. Agonist dose-dependent phosphorylation by protein kinase A and G protein-coupled receptor kinase regulates beta2 adrenoceptor coupling to G(i) proteins in cardiomyocytes. J Biol Chem. 2009; 284(47):32279-32287.
    • (2009) J Biol Chem , vol.284 , Issue.47 , pp. 32279-32287
    • Liu, R.1    Ramani, B.2    Soto, D.3    De Arcangelis, V.4    Xiang, Y.5
  • 25
    • 17144439929 scopus 로고    scopus 로고
    • Beta-adrenergic signaling in the heart: Dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins
    • Xiao RP. Beta-adrenergic signaling in the heart: dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins. Sci STKE. 2001;2001(104):re15.
    • (2001) Sci STKE , vol.2001 , Issue.104 , pp. re15
    • Xiao, R.P.1
  • 27
    • 0037040840 scopus 로고    scopus 로고
    • Localization of cardiac sodium channels in caveolin-rich membrane domains: Regulation of sodium current amplitude
    • Yarbrough TL, Lu T, Lee HC, Shibata EF. Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude. Circ Res. 2002;90(4):443-449.
    • (2002) Circ Res , vol.90 , Issue.4 , pp. 443-449
    • Yarbrough, T.L.1    Lu, T.2    Lee, H.C.3    Shibata, E.F.4
  • 28
    • 0034677985 scopus 로고    scopus 로고
    • Differential targeting of Shakerlike potassium channels to lipid rafts
    • Martens JR, Navarro-Polanco R, Coppock EA, et al. Differential targeting of Shakerlike potassium channels to lipid rafts. J Biol Chem. 2000;275(11):7443-7446.
    • (2000) J Biol Chem , vol.275 , Issue.11 , pp. 7443-7446
    • Martens, J.R.1    Navarro-Polanco, R.2    Coppock, E.A.3
  • 29
    • 0034711504 scopus 로고    scopus 로고
    • Ignition of calcium sparks in arterial and cardiac muscle through caveolae
    • Lohn M, Furstenau M, Sagach V, et al. Ignition of calcium sparks in arterial and cardiac muscle through caveolae. Circ Res. 2000;87(11):1034-1039.
    • (2000) Circ Res , vol.87 , Issue.11 , pp. 1034-1039
    • Lohn, M.1    Furstenau, M.2    Sagach, V.3
  • 30
    • 0033729377 scopus 로고    scopus 로고
    • G i)-dependent localization of beta 2)-adrenergic receptor signaling to L-type Ca(2+) channels
    • Chen-Izu Y, Xiao RP, Izu LT, et al. G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels. Biophys J. 2000;79(5):2547-2556.
    • (2000) Biophys J , vol.79 , Issue.5 , pp. 2547-2556
    • Chen-Izu, Y.1    Xiao, R.P.2    Izu, L.T.3
  • 31
    • 0037050009 scopus 로고    scopus 로고
    • Seven-transmembrane-spanning receptors and heart function
    • Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature. 2002;415(6868):206-212.
    • (2002) Nature , vol.415 , Issue.6868 , pp. 206-212
    • Rockman, H.A.1    Koch, W.J.2    Lefkowitz, R.J.3
  • 32
    • 0022980843 scopus 로고
    • Beta 1-and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: Coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure
    • Bristow MR, Ginsburg R, Umans V, et al. Beta 1-and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure. Circ Res. 1986;59(3):297-309.
    • (1986) Circ Res , vol.59 , Issue.3 , pp. 297-309
    • Bristow, M.R.1    Ginsburg, R.2    Umans, V.3
  • 33
    • 19644397920 scopus 로고    scopus 로고
    • Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/phosphoinositide 3-kinase complex
    • Perrino C, Naga Prasad SV, Schroder JN, Hata JA, Milano C, Rockman HA. Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/phosphoinositide 3-kinase complex. Circulation. 2005;111(20):2579-2587.
    • (2005) Circulation , vol.111 , Issue.20 , pp. 2579-2587
    • Perrino, C.1    Naga Prasad, S.V.2    Schroder, J.N.3    Hata, J.A.4    Milano, C.5    Rockman, H.A.6
  • 34
    • 0035375104 scopus 로고    scopus 로고
    • Agonistdependent recruitment of phosphoinositide 3-kinase to the membrane by betaadrenergic receptor kinase 1. A role in receptor sequestration
    • Naga Prasad SV, Barak LS, Rapacciuolo A, Caron MG, Rockman HA. Agonistdependent recruitment of phosphoinositide 3-kinase to the membrane by betaadrenergic receptor kinase 1. A role in receptor sequestration. J Biol Chem. 2001;276(22):18953-18959.
    • (2001) J Biol Chem , vol.276 , Issue.22 , pp. 18953-18959
    • Naga Prasad, S.V.1    Barak, L.S.2    Rapacciuolo, A.3    Caron, M.G.4    Rockman, H.A.5
  • 35
    • 0036327388 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex
    • Naga Prasad SV, Laporte SA, Chamberlain D, Caron MG, Barak L, Rockman HA. Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex. J Cell Biol. 2002; 158(3):563-575.
    • (2002) J Cell Biol , vol.158 , Issue.3 , pp. 563-575
    • Naga Prasad, S.V.1    Laporte, S.A.2    Chamberlain, D.3    Caron, M.G.4    Barak, L.5    Rockman, H.A.6
  • 36
    • 38549099762 scopus 로고    scopus 로고
    • Dynamic regulation of phosphoinositide 3-kinase-gamma activity and beta-adrenergic receptor trafficking in end-stage human heart failure
    • Perrino C, Schroder JN, Lima B, et al. Dynamic regulation of phosphoinositide 3-kinase-gamma activity and beta-adrenergic receptor trafficking in end-stage human heart failure. Circulation. 2007;116(22):2571-2579.
    • (2007) Circulation , vol.116 , Issue.22 , pp. 2571-2579
    • Perrino, C.1    Schroder, J.N.2    Lima, B.3
  • 37
    • 33748751670 scopus 로고    scopus 로고
    • Trafficking ofG protein-coupled receptors
    • Drake MT, Shenoy SK, Lefkowitz RJ. Trafficking ofG protein-coupled receptors. Circ Res. 2006;99(6):570-582.
    • (2006) Circ Res , vol.99 , Issue.6 , pp. 570-582
    • Drake, M.T.1    Shenoy, S.K.2    Lefkowitz, R.J.3
  • 38
    • 0036500494 scopus 로고    scopus 로고
    • Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes
    • Zaccolo M, Pozzan T. Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes. Science. 2002;295(5560):1711-1715.
    • (2002) Science , vol.295 , Issue.5560 , pp. 1711-1715
    • Zaccolo, M.1    Pozzan, T.2
  • 39
    • 24144462378 scopus 로고    scopus 로고
    • G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes
    • Head BP, Patel HH, Roth DM, et al. G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes. J Biol Chem. 2005;280(35):31036-31044.
    • (2005) J Biol Chem , vol.280 , Issue.35 , pp. 31036-31044
    • Head, B.P.1    Patel, H.H.2    Roth, D.M.3
  • 40
    • 79952185507 scopus 로고    scopus 로고
    • Left ventricular dysfunction in murine models of heart failure and in failing human heart is associated with a selective decrease in the expression of caveolin-3
    • Feiner EC, Chung P, Jasmin JF, et al. Left ventricular dysfunction in murine models of heart failure and in failing human heart is associated with a selective decrease in the expression of caveolin-3. J Card Fail. 2011;17(3):253-263.
    • (2011) J Card Fail , vol.17 , Issue.3 , pp. 253-263
    • Feiner, E.C.1    Chung, P.2    Jasmin, J.F.3
  • 41
    • 77950286813 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation
    • Nikolaev VO, Moshkov A, Lyon AR, et al. Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science. 2010;327(5973):1653-1657.
    • (2010) Science , vol.327 , Issue.5973 , pp. 1653-1657
    • Nikolaev, V.O.1    Moshkov, A.2    Lyon, A.R.3
  • 42
    • 0034724376 scopus 로고    scopus 로고
    • Regulation of PKA binding to AKAPs in the heart: Alterations in human heart failure
    • Zakhary DR, Moravec CS, Bond M. Regulation of PKA binding to AKAPs in the heart: alterations in human heart failure. Circulation. 2000;101(12):1459-1464.
    • (2000) Circulation , vol.101 , Issue.12 , pp. 1459-1464
    • Zakhary, D.R.1    Moravec, C.S.2    Bond, M.3
  • 43
    • 0030957355 scopus 로고    scopus 로고
    • Clathrin-coated vesicle formation and protein sorting: An integrated process
    • Schmid SL. Clathrin-coated vesicle formation and protein sorting: an integrated process. Annu Rev Biochem. 1997;66:511-548.
    • (1997) Annu Rev Biochem , vol.66 , pp. 511-548
    • Schmid, S.L.1
  • 44
    • 2342451911 scopus 로고    scopus 로고
    • G-protein coupled receptors in lipid rafts and caveolae: How, when and why do they go there?
    • Chini B, Parenti M. G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there? J Mol Endocrinol. 2004;32(2):325-338.
    • (2004) J Mol Endocrinol , vol.32 , Issue.2 , pp. 325-338
    • Chini, B.1    Parenti, M.2
  • 45
    • 69249137477 scopus 로고    scopus 로고
    • Endocytosis and signalling: Intertwining molecular networks
    • Sorkin A, von Zastrow M. Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol. 2009;10(9):609-622.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.9 , pp. 609-622
    • Sorkin, A.1    Von Zastrow, M.2
  • 46
    • 33947314576 scopus 로고    scopus 로고
    • Regulation of receptor trafficking by GRKs and arrestins
    • Moore CA, Milano SK, Benovic JL. Regulation of receptor trafficking by GRKs and arrestins. Annu Rev Physiol. 2007;69:451-482.
    • (2007) Annu Rev Physiol , vol.69 , pp. 451-482
    • Moore, C.A.1    Milano, S.K.2    Benovic, J.L.3
  • 47
    • 0030593035 scopus 로고    scopus 로고
    • Role of beta-arrestin in mediating agonist-promoted Gprotein-coupled receptor internalization
    • Ferguson SS, Downey 3rd WE, Colapietro AM, Barak LS, Menard L, Caron MG. Role of beta-arrestin in mediating agonist-promoted Gprotein-coupled receptor internalization. Science. 1996;271(5247):363-366.
    • (1996) Science , vol.271 , Issue.5247 , pp. 363-366
    • Ferguson, S.S.1    Downey, W.E.2    Colapietro, A.M.3    Barak, L.S.4    Menard, L.5    Caron, M.G.6
  • 48
    • 0037128214 scopus 로고    scopus 로고
    • G protein-coupled receptor/arrestin3 modulation of the endocytic machinery
    • Santini F, Gaidarov I, Keen JH. G protein-coupled receptor/arrestin3 modulation of the endocytic machinery. J Cell Biol. 2002;156(4):665-676.
    • (2002) J Cell Biol , vol.156 , Issue.4 , pp. 665-676
    • Santini, F.1    Gaidarov, I.2    Keen, J.H.3
  • 49
    • 0028840355 scopus 로고
    • Interaction of tyrosine-based sorting signals with clathrin-associated proteins
    • Ohno H, Stewart J, Fournier MC, et al. Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science. 1995;269(5232):1872-1875.
    • (1995) Science , vol.269 , Issue.5232 , pp. 1872-1875
    • Ohno, H.1    Stewart, J.2    Fournier, M.C.3
  • 50
    • 21144445951 scopus 로고    scopus 로고
    • Phosphatidylinositol-4, 5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2
    • Honing S, Ricotta D, Krauss M, et al. Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2. Mol Cell. 2005;18(5):519-531.
    • (2005) Mol Cell , vol.18 , Issue.5 , pp. 519-531
    • Honing, S.1    Ricotta, D.2    Krauss, M.3
  • 52
    • 33644838018 scopus 로고    scopus 로고
    • Clathrin-independent endocytosis: New insights into caveolae and non-caveolar lipid raft carriers
    • Kirkham M, Parton RG. Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta. 2005;1746(3):349-363.
    • (2005) Biochim Biophys Acta , vol.1746 , Issue.3 , pp. 349-363
    • Kirkham, M.1    Parton, R.G.2
  • 53
    • 34547114456 scopus 로고    scopus 로고
    • Pathways of clathrin-independent endocytosis
    • Mayor S, Pagano RE. Pathways of clathrin-independent endocytosis. Nat Rev Mol Cell Biol. 2007;8(8):603-612.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.8 , pp. 603-612
    • Mayor, S.1    Pagano, R.E.2
  • 54
    • 0030739938 scopus 로고    scopus 로고
    • The SH3p4/Sh3p8/SH3p13 protein family: Binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain
    • Ringstad N, Nemoto Y, De Camilli P. The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain. Proc Natl Acad Sci USA. 1997;94(16):8569-8574.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.16 , pp. 8569-8574
    • Ringstad, N.1    Nemoto, Y.2    De Camilli, P.3
  • 55
    • 81355153885 scopus 로고    scopus 로고
    • Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission
    • Milosevic I, Giovedi S, Lou X, et al. Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission. Neuron. 2011;72(4):587-601.
    • (2011) Neuron , vol.72 , Issue.4 , pp. 587-601
    • Milosevic, I.1    Giovedi, S.2    Lou, X.3
  • 56
    • 84922054440 scopus 로고    scopus 로고
    • Endophilin marks and controls a clathrin-independent endocytic pathway
    • Boucrot E, Ferreira AP, Almeida-Souza L, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517(7535):460-465.
    • (2015) Nature , vol.517 , Issue.7535 , pp. 460-465
    • Boucrot, E.1    Ferreira, A.P.2    Almeida-Souza, L.3
  • 57
    • 79960720320 scopus 로고    scopus 로고
    • Molecular mechanism and physiological functions of clathrin-mediated endocytosis
    • McMahon HT, Boucrot E. Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat Rev Mol Cell Biol. 2011;12(8):517-533.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , Issue.8 , pp. 517-533
    • McMahon, H.T.1    Boucrot, E.2
  • 58
    • 84874771850 scopus 로고    scopus 로고
    • Cooperative recruitment of dynamin and BIN/amphiphysin/Rvs (BAR) domain-containing proteins leads to GTP-dependent membrane scission
    • Meinecke M, Boucrot E, Camdere G, Hon WC, Mittal R, McMahon HT. Cooperative recruitment of dynamin and BIN/amphiphysin/Rvs (BAR) domain-containing proteins leads to GTP-dependent membrane scission. J Biol Chem. 2013; 288(9):6651-6661.
    • (2013) J Biol Chem , vol.288 , Issue.9 , pp. 6651-6661
    • Meinecke, M.1    Boucrot, E.2    Camdere, G.3    Hon, W.C.4    Mittal, R.5    McMahon, H.T.6
  • 59
    • 0033607141 scopus 로고    scopus 로고
    • Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor
    • Tang Y, Hu LA, Miller WE, et al. Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor. Proc Natl Acad Sci USA. 1999;96(22):12559-12564.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.22 , pp. 12559-12564
    • Tang, Y.1    Hu, L.A.2    Miller, W.E.3
  • 60
    • 0035976611 scopus 로고    scopus 로고
    • Caveolae: A once-elusive structure gets some respect
    • Marx J. Caveolae: a once-elusive structure gets some respect. Science. 2001; 294(5548):1862-1865.
    • (2001) Science , vol.294 , Issue.5548 , pp. 1862-1865
    • Marx, J.1
  • 61
    • 0035029169 scopus 로고    scopus 로고
    • Compartmentation of G protein-coupled signaling pathways in cardiac myocytes
    • Steinberg SF, Brunton LL. Compartmentation of G protein-coupled signaling pathways in cardiac myocytes. Annu Rev Pharmacol Toxicol. 2001;41:751-773.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 751-773
    • Steinberg, S.F.1    Brunton, L.L.2
  • 62
    • 0034705543 scopus 로고    scopus 로고
    • Gravin-mediated formation of signaling complexes in beta 2-adrenergic receptor desensitization and resensitization
    • Lin F, Wang H, Malbon CC. Gravin-mediated formation of signaling complexes in beta 2-adrenergic receptor desensitization and resensitization. J Biol Chem. 2000;275(25):19025-19034.
    • (2000) J Biol Chem , vol.275 , Issue.25 , pp. 19025-19034
    • Lin, F.1    Wang, H.2    Malbon, C.C.3
  • 63
    • 0042316928 scopus 로고    scopus 로고
    • Protein kinase A and G proteincoupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways
    • Rapacciuolo A, Suvarna S, Barki-Harrington L, et al. Protein kinase A and G proteincoupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways. J Biol Chem. 2003;278(37):35403-35411.
    • (2003) J Biol Chem , vol.278 , Issue.37 , pp. 35403-35411
    • Rapacciuolo, A.1    Suvarna, S.2    Barki-Harrington, L.3
  • 64
    • 0037072777 scopus 로고    scopus 로고
    • The PDZ binding motif of the beta 1 adrenergic receptor modulates receptor trafficking and signaling in cardiac myocytes
    • Xiang Y, Devic E, Kobilka B. The PDZ binding motif of the beta 1 adrenergic receptor modulates receptor trafficking and signaling in cardiac myocytes. J Biol Chem. 2002;277(37):33783-33790.
    • (2002) J Biol Chem , vol.277 , Issue.37 , pp. 33783-33790
    • Xiang, Y.1    Devic, E.2    Kobilka, B.3
  • 65
    • 0028791335 scopus 로고
    • Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1
    • Ferguson SS, Menard L, Barak LS, Koch WJ, Colapietro AM, Caron MG. Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1. J Biol Chem. 1995; 270(42):24782-24789.
    • (1995) J Biol Chem , vol.270 , Issue.42 , pp. 24782-24789
    • Ferguson, S.S.1    Menard, L.2    Barak, L.S.3    Koch, W.J.4    Colapietro, A.M.5    Caron, M.G.6
  • 66
    • 0032571340 scopus 로고    scopus 로고
    • Molecular mechanisms of G proteincoupled receptor desensitization and resensitization
    • Ferguson SS, Zhang J, Barak LS, Caron MG. Molecular mechanisms of G proteincoupled receptor desensitization and resensitization. Life Sci. 1998;62(17-18): 1561-1565.
    • (1998) Life Sci , vol.62 , Issue.17-18 , pp. 1561-1565
    • Ferguson, S.S.1    Zhang, J.2    Barak, L.S.3    Caron, M.G.4
  • 67
    • 0035055204 scopus 로고    scopus 로고
    • Diversity and specificity in the regulated endocytic membrane trafficking of G-protein-coupled receptors
    • Tsao PI, von Zastrow M. Diversity and specificity in the regulated endocytic membrane trafficking of G-protein-coupled receptors. Pharmacol Ther. 2001; 89(2):139-147.
    • (2001) Pharmacol Ther , vol.89 , Issue.2 , pp. 139-147
    • Tsao, P.I.1    Von Zastrow, M.2
  • 68
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G proteincoupled receptor regulation
    • Krupnick JG, Benovic JL. The role of receptor kinases and arrestins in G proteincoupled receptor regulation. Annu Rev Pharmacol Toxicol. 1998;38:289-319.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 69
    • 41149090339 scopus 로고    scopus 로고
    • Regulation of GPCRs by endocytic membrane trafficking and its potential implications
    • Hanyaloglu AC, von Zastrow M. Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu Rev Pharmacol Toxicol. 2008;48:537-568.
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 537-568
    • Hanyaloglu, A.C.1    Von Zastrow, M.2
  • 70
    • 0344310763 scopus 로고    scopus 로고
    • Mechanisms of beta-adrenergic receptor desensitization and resensitization
    • Lefkowitz RJ, Pitcher J, Krueger K, Daaka Y. Mechanisms of beta-adrenergic receptor desensitization and resensitization. Adv Pharmacol. 1998;42:416-420.
    • (1998) Adv Pharmacol , vol.42 , pp. 416-420
    • Lefkowitz, R.J.1    Pitcher, J.2    Krueger, K.3    Daaka, Y.4
  • 71
    • 0022257530 scopus 로고
    • Phosphorylation of the mammalian betaadrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein
    • Benovic JL, Pike LJ, Cerione RA, et al. Phosphorylation of the mammalian betaadrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein. J Biol Chem. 1985;260(11):7094-7101.
    • (1985) J Biol Chem , vol.260 , Issue.11 , pp. 7094-7101
    • Benovic, J.L.1    Pike, L.J.2    Cerione, R.A.3
  • 72
    • 0032563291 scopus 로고    scopus 로고
    • G protein-coupled receptors. III New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization
    • Lefkowitz RJ. G protein-coupled receptors. III New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization. J Biol Chem. 1998; 273(30):18677-18680.
    • (1998) J Biol Chem , vol.273 , Issue.30 , pp. 18677-18680
    • Lefkowitz, R.J.1
  • 73
    • 84857471063 scopus 로고    scopus 로고
    • Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins
    • Magalhaes AC, Dunn H, Ferguson SS. Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins. Br J Pharmacol. 2012;165(6):1717-1736.
    • (2012) Br J Pharmacol , vol.165 , Issue.6 , pp. 1717-1736
    • Magalhaes, A.C.1    Dunn, H.2    Ferguson, S.S.3
  • 74
    • 0037163048 scopus 로고    scopus 로고
    • Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system
    • Zamah AM, Delahunty M, Luttrell LM, Lefkowitz RJ. Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system. J Biol Chem. 2002;277(34):31249-31256.
    • (2002) J Biol Chem , vol.277 , Issue.34 , pp. 31249-31256
    • Zamah, A.M.1    Delahunty, M.2    Luttrell, L.M.3    Lefkowitz, R.J.4
  • 75
    • 38349124756 scopus 로고    scopus 로고
    • Norepinephrine-and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes
    • Wang Y, De Arcangelis V, Gao X, Ramani B, Jung YS, Xiang Y. Norepinephrine-and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes. J Biol Chem. 2008;283(4):1799-1807.
    • (2008) J Biol Chem , vol.283 , Issue.4 , pp. 1799-1807
    • Wang, Y.1    De Arcangelis, V.2    Gao, X.3    Ramani, B.4    Jung, Y.S.5    Xiang, Y.6
  • 76
    • 0033575916 scopus 로고    scopus 로고
    • A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor
    • Cao TT, Deacon HW, Reczek D, Bretscher A, von Zastrow M. A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor. Nature. 1999;401(6750):286-290.
    • (1999) Nature , vol.401 , Issue.6750 , pp. 286-290
    • Cao, T.T.1    Deacon, H.W.2    Reczek, D.3    Bretscher, A.4    Von Zastrow, M.5
  • 77
    • 84922594993 scopus 로고    scopus 로고
    • Insulin induces IRS2-dependent and GRK2-mediated beta2AR internalization to attenuate betaAR signaling in cardiomyocytes
    • Fu Q, Xu B, Parikh D, Cervantes D, Xiang YK. Insulin induces IRS2-dependent and GRK2-mediated beta2AR internalization to attenuate betaAR signaling in cardiomyocytes. Cell Signal. 2015;27(3):707-715.
    • (2015) Cell Signal , vol.27 , Issue.3 , pp. 707-715
    • Fu, Q.1    Xu, B.2    Parikh, D.3    Cervantes, D.4    Xiang, Y.K.5
  • 78
    • 84880731037 scopus 로고    scopus 로고
    • Gbetagamma-independent recruitment of G-protein coupled receptor kinase 2 drives tumor necrosis factor alpha-induced cardiac beta-adrenergic receptor dysfunction
    • Vasudevan NT, Mohan ML, Gupta MK, et al. Gbetagamma-independent recruitment of G-protein coupled receptor kinase 2 drives tumor necrosis factor alpha-induced cardiac beta-adrenergic receptor dysfunction. Circulation. 2013;128(4):377-387.
    • (2013) Circulation , vol.128 , Issue.4 , pp. 377-387
    • Vasudevan, N.T.1    Mohan, M.L.2    Gupta, M.K.3
  • 79
    • 84927786776 scopus 로고    scopus 로고
    • Beta-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling
    • Tilley DG, Zhu W, Myers VD, et al. beta-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling. Circulation. 2014;130(20):1800-1811.
    • (2014) Circulation , vol.130 , Issue.20 , pp. 1800-1811
    • Tilley, D.G.1    Zhu, W.2    Myers, V.D.3
  • 80
    • 0037155869 scopus 로고    scopus 로고
    • Insulin stimulates phosphorylation of the beta 2-adrenergic receptor by the insulin receptor, creating a potent feedback inhibitor of its tyrosine kinase
    • Doronin S, Wang Hy HY, Malbon CC. Insulin stimulates phosphorylation of the beta 2-adrenergic receptor by the insulin receptor, creating a potent feedback inhibitor of its tyrosine kinase. J Biol Chem. 2002;277(12):10698-10703.
    • (2002) J Biol Chem , vol.277 , Issue.12 , pp. 10698-10703
    • Doronin, S.1    Wang Hy, H.Y.2    Malbon, C.C.3
  • 81
    • 0027101956 scopus 로고
    • Cross-talk between tyrosine kinase and G-protein-linked receptors. Phosphorylation of beta 2-adrenergic receptors in response to insulin
    • Hadcock JR, Port JD, Gelman MS, Malbon CC. Cross-talk between tyrosine kinase and G-protein-linked receptors. Phosphorylation of beta 2-adrenergic receptors in response to insulin. J Biol Chem. 1992;267(36):26017-26022.
    • (1992) J Biol Chem , vol.267 , Issue.36 , pp. 26017-26022
    • Hadcock, J.R.1    Port, J.D.2    Gelman, M.S.3    Malbon, C.C.4
  • 82
    • 0036856299 scopus 로고    scopus 로고
    • Pp60Src mediates insulin-stimulated sequestration of the beta 2)-adrenergic receptor: Insulin stimulates pp60Src phosphorylation and activation
    • Shumay E, Song X, Wang HY, Malbon CC. pp60Src mediates insulin-stimulated sequestration of the beta(2)-adrenergic receptor: insulin stimulates pp60Src phosphorylation and activation. Mol Biol Cell. 2002;13(11):3943-3954.
    • (2002) Mol Biol Cell , vol.13 , Issue.11 , pp. 3943-3954
    • Shumay, E.1    Song, X.2    Wang, H.Y.3    Malbon, C.C.4
  • 83
    • 0032484196 scopus 로고    scopus 로고
    • Insulin stimulates sequestration of betaadrenergic receptors and enhanced association of beta-adrenergic receptors with Grb2 via tyrosine 350
    • Karoor V, Wang L, Wang HY, Malbon CC. Insulin stimulates sequestration of betaadrenergic receptors and enhanced association of beta-adrenergic receptors with Grb2 via tyrosine 350. J Biol Chem. 1998;273(49):33035-33041.
    • (1998) J Biol Chem , vol.273 , Issue.49 , pp. 33035-33041
    • Karoor, V.1    Wang, L.2    Wang, H.Y.3    Malbon, C.C.4
  • 84
    • 84904994548 scopus 로고    scopus 로고
    • Insulin inhibits cardiac contractility by inducing a Gi-biased beta2-adrenergic signaling in hearts
    • Fu Q, Xu B, Liu Y, et al. Insulin inhibits cardiac contractility by inducing a Gi-biased beta2-adrenergic signaling in hearts. Diabetes. 2014;63(8):2676-2689.
    • (2014) Diabetes , vol.63 , Issue.8 , pp. 2676-2689
    • Fu, Q.1    Xu, B.2    Liu, Y.3
  • 85
    • 84913556601 scopus 로고    scopus 로고
    • Demonstration of a direct interaction between beta2-adrenergic receptor and insulin receptor by BRET and bioinformatics
    • Mandic M, Drinovec L, Glisic S, Veljkovic N, Nohr J, Vrecl M. Demonstration of a direct interaction between beta2-adrenergic receptor and insulin receptor by BRET and bioinformatics. PLoS One. 2014;9(11):e112664.
    • (2014) PLoS One , vol.9 , Issue.11 , pp. e112664
    • Mandic, M.1    Drinovec, L.2    Glisic, S.3    Veljkovic, N.4    Nohr, J.5    Vrecl, M.6
  • 86
    • 0027500394 scopus 로고
    • Altered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341
    • Moffett S, Mouillac B, Bonin H, Bouvier M. Altered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341. EMBO J. 1993;12(1):349-356.
    • (1993) EMBO J , vol.12 , Issue.1 , pp. 349-356
    • Moffett, S.1    Mouillac, B.2    Bonin, H.3    Bouvier, M.4
  • 87
    • 20144375061 scopus 로고    scopus 로고
    • An acylation cycle regulates localization and activity of palmitoylated Ras isoforms
    • Rocks O, Peyker A, Kahms M, et al. An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science. 2005;307(5716):1746-1752.
    • (2005) Science , vol.307 , Issue.5716 , pp. 1746-1752
    • Rocks, O.1    Peyker, A.2    Kahms, M.3
  • 88
    • 33646534202 scopus 로고    scopus 로고
    • Co-ordinated covalent modification of G-protein coupled receptors
    • Torrecilla I, Tobin AB. Co-ordinated covalent modification of G-protein coupled receptors. Curr Pharm Des. 2006;12(14):1797-1808.
    • (2006) Curr Pharm des , vol.12 , Issue.14 , pp. 1797-1808
    • Torrecilla, I.1    Tobin, A.B.2
  • 89
    • 0024544232 scopus 로고
    • Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor
    • O'Dowd BF, Hnatowich M, Caron MG, Lefkowitz RJ, Bouvier M. Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. J Biol Chem. 1989; 264(13):7564-7569.
    • (1989) J Biol Chem , vol.264 , Issue.13 , pp. 7564-7569
    • O'Dowd, B.F.1    Hnatowich, M.2    Caron, M.G.3    Lefkowitz, R.J.4    Bouvier, M.5
  • 90
    • 34548379109 scopus 로고    scopus 로고
    • A-kinase anchoring proteins: Trafficking in G-protein-coupled receptors and the proteins that regulate receptor biology
    • Malbon CC. A-kinase anchoring proteins: trafficking in G-protein-coupled receptors and the proteins that regulate receptor biology. Curr Opin Drug Discov Devel. 2007;10(5):573-579.
    • (2007) Curr Opin Drug Discov Devel , vol.10 , Issue.5 , pp. 573-579
    • Malbon, C.C.1
  • 91
    • 70350469968 scopus 로고    scopus 로고
    • Adenylyl cyclase-A-kinase anchoring protein complexes: The next dimension in cAMP signaling
    • Dessauer CW. Adenylyl cyclase-A-kinase anchoring protein complexes: the next dimension in cAMP signaling. Mol Pharmacol. 2009;76(5):935-941.
    • (2009) Mol Pharmacol , vol.76 , Issue.5 , pp. 935-941
    • Dessauer, C.W.1
  • 92
    • 71749107983 scopus 로고    scopus 로고
    • Differential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes
    • De Arcangelis V, Liu R, Soto D, Xiang Y. Differential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes. J Biol Chem. 2009;284(49):33824-33832.
    • (2009) J Biol Chem , vol.284 , Issue.49 , pp. 33824-33832
    • De Arcangelis, V.1    Liu, R.2    Soto, D.3    Xiang, Y.4
  • 93
    • 84864978744 scopus 로고    scopus 로고
    • Palmitoylation regulates intracellular trafficking of beta2 adrenergic receptor/arrestin/phosphodiesterase 4D complexes in cardiomyocytes
    • Liu R, Wang D, Shi Q, Fu Q, Hizon S, Xiang YK. Palmitoylation regulates intracellular trafficking of beta2 adrenergic receptor/arrestin/phosphodiesterase 4D complexes in cardiomyocytes. PLoS One. 2012;7(8):e42658.
    • (2012) PLoS One , vol.7 , Issue.8 , pp. e42658
    • Liu, R.1    Wang, D.2    Shi, Q.3    Fu, Q.4    Hizon, S.5    Xiang, Y.K.6
  • 94
    • 77955853530 scopus 로고    scopus 로고
    • Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex
    • Halls ML, Cooper DM. Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex. EMBO J. 2010;29(16):2772-2787.
    • (2010) EMBO J , vol.29 , Issue.16 , pp. 2772-2787
    • Halls, M.L.1    Cooper, D.M.2
  • 95
    • 33646378423 scopus 로고    scopus 로고
    • Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation
    • Vaughan DJ, Millman EE, Godines V, et al. Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. J Biol Chem. 2006;281(11):7684-7692.
    • (2006) J Biol Chem , vol.281 , Issue.11 , pp. 7684-7692
    • Vaughan, D.J.1    Millman, E.E.2    Godines, V.3
  • 96
    • 78651092657 scopus 로고    scopus 로고
    • Role of ubiquitination in endocytic trafficking of G-protein-coupled receptors
    • Hislop JN, von Zastrow M. Role of ubiquitination in endocytic trafficking of G-protein-coupled receptors. Traffic. 2011;12(2):137-148.
    • (2011) Traffic , vol.12 , Issue.2 , pp. 137-148
    • Hislop, J.N.1    Von Zastrow, M.2
  • 98
    • 9744227183 scopus 로고    scopus 로고
    • Ubiquitin: Structures, functions, mechanisms
    • Pickart CM, Eddins MJ. Ubiquitin: structures, functions, mechanisms. Biochim Biophys Acta. 2004;1695(1-3):55-72.
    • (2004) Biochim Biophys Acta , vol.1695 , Issue.1-3 , pp. 55-72
    • Pickart, C.M.1    Eddins, M.J.2
  • 99
    • 79953296222 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains
    • Xiao K, Shenoy SK. Beta2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains. J Biol Chem. 2011;286(14):12785-12795.
    • (2011) J Biol Chem , vol.286 , Issue.14 , pp. 12785-12795
    • Xiao, K.1    Shenoy, S.K.2
  • 100
    • 0035834428 scopus 로고    scopus 로고
    • Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin
    • Shenoy SK, McDonald PH, Kohout TA, Lefkowitz RJ. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science. 2001;294(5545):1307-1313.
    • (2001) Science , vol.294 , Issue.5545 , pp. 1307-1313
    • Shenoy, S.K.1    McDonald, P.H.2    Kohout, T.A.3    Lefkowitz, R.J.4
  • 101
    • 22744455819 scopus 로고    scopus 로고
    • Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling
    • Hanyaloglu AC, McCullagh E, von Zastrow M. Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling. EMBO J. 2005;24(13):2265-2283.
    • (2005) EMBO J , vol.24 , Issue.13 , pp. 2265-2283
    • Hanyaloglu, A.C.1    McCullagh, E.2    Von Zastrow, M.3
  • 102
    • 52049117442 scopus 로고    scopus 로고
    • Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor
    • Shenoy SK, Xiao K, Venkataramanan V, Snyder PM, Freedman NJ, Weissman AM. Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. J Biol Chem. 2008;283(32):22166-22176.
    • (2008) J Biol Chem , vol.283 , Issue.32 , pp. 22166-22176
    • Shenoy, S.K.1    Xiao, K.2    Venkataramanan, V.3    Snyder, P.M.4    Freedman, N.J.5    Weissman, A.M.6
  • 103
    • 77955058247 scopus 로고    scopus 로고
    • Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the beta2-adrenergic receptor
    • Nabhan JF, Pan H, Lu Q. Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the beta2-adrenergic receptor. EMBO Rep. 2010;11(8):605-611.
    • (2010) EMBO Rep , vol.11 , Issue.8 , pp. 605-611
    • Nabhan, J.F.1    Pan, H.2    Lu, Q.3
  • 104
    • 28344456279 scopus 로고    scopus 로고
    • A genomic and functional inventory of deubiquitinating enzymes
    • Nijman SM, Luna-Vargas MP, Velds A, et al. A genomic and functional inventory of deubiquitinating enzymes. Cell. 2005;123(5):773-786.
    • (2005) Cell , vol.123 , Issue.5 , pp. 773-786
    • Nijman, S.M.1    Luna-Vargas, M.P.2    Velds, A.3
  • 105
    • 67649556158 scopus 로고    scopus 로고
    • The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization
    • Berthouze M, Venkataramanan V, Li Y, Shenoy SK. The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization. EMBO J. 2009;28(12):1684-1696.
    • (2009) EMBO J , vol.28 , Issue.12 , pp. 1684-1696
    • Berthouze, M.1    Venkataramanan, V.2    Li, Y.3    Shenoy, S.K.4
  • 106
    • 80053598334 scopus 로고    scopus 로고
    • Isoform-specific localization of the deubiquitinase USP33 to the Golgi apparatus
    • Thorne C, Eccles RL, Coulson JM, Urbe S, Clague MJ. Isoform-specific localization of the deubiquitinase USP33 to the Golgi apparatus. Traffic. 2011; 12(11):1563-1574.
    • (2011) Traffic , vol.12 , Issue.11 , pp. 1563-1574
    • Thorne, C.1    Eccles, R.L.2    Coulson, J.M.3    Urbe, S.4    Clague, M.J.5
  • 107
    • 0021019784 scopus 로고
    • Characterization of an altered membrane form of the beta-adrenergic receptor produced during agonist-induced desensitization
    • Waldo GL, Northup JK, Perkins JP, Harden TK. Characterization of an altered membrane form of the beta-adrenergic receptor produced during agonist-induced desensitization. J Biol Chem. 1983;258(22):13900-13908.
    • (1983) J Biol Chem , vol.258 , Issue.22 , pp. 13900-13908
    • Waldo, G.L.1    Northup, J.K.2    Perkins, J.P.3    Harden, T.K.4
  • 108
    • 84858203893 scopus 로고    scopus 로고
    • Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling
    • Lohse MJ, Nuber S, Hoffmann C. Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling. Pharmacol Rev. 2012;64(2):299-336.
    • (2012) Pharmacol Rev , vol.64 , Issue.2 , pp. 299-336
    • Lohse, M.J.1    Nuber, S.2    Hoffmann, C.3
  • 109
    • 70349309325 scopus 로고    scopus 로고
    • Sustained cyclic AMP production by parathyroid hormone receptor endocytosis
    • Ferrandon S, Feinstein TN, Castro M, et al. Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. Nat Chem Biol. 2009;5(10):734-742.
    • (2009) Nat Chem Biol , vol.5 , Issue.10 , pp. 734-742
    • Ferrandon, S.1    Feinstein, T.N.2    Castro, M.3
  • 110
    • 79955073671 scopus 로고    scopus 로고
    • Retromer terminates the generation of cAMP by internalized PTH receptors
    • Feinstein TN, Wehbi VL, Ardura JA, et al. Retromer terminates the generation of cAMP by internalized PTH receptors. Nat Chem Biol. 2011;7(5):278-284.
    • (2011) Nat Chem Biol , vol.7 , Issue.5 , pp. 278-284
    • Feinstein, T.N.1    Wehbi, V.L.2    Ardura, J.A.3
  • 111
    • 69249105154 scopus 로고    scopus 로고
    • Persistent cAMP-signals triggered by internalized G-protein-coupled receptors
    • Calebiro D, Nikolaev VO, Gagliani MC, et al. Persistent cAMP-signals triggered by internalized G-protein-coupled receptors. PLoS Biol. 2009;7(8):e1000172.
    • (2009) PLoS Biol , vol.7 , Issue.8 , pp. e1000172
    • Calebiro, D.1    Nikolaev, V.O.2    Gagliani, M.C.3
  • 112
    • 84860914331 scopus 로고    scopus 로고
    • Persistent cAMP signaling by internalized TSH receptors occurs in thyroid but not in HEK293 cells
    • Werthmann RC, Volpe S, Lohse MJ, Calebiro D. Persistent cAMP signaling by internalized TSH receptors occurs in thyroid but not in HEK293 cells. FASEB J. 2012;26(5):2043-2048.
    • (2012) FASEB J , vol.26 , Issue.5 , pp. 2043-2048
    • Werthmann, R.C.1    Volpe, S.2    Lohse, M.J.3    Calebiro, D.4
  • 113
    • 77954710506 scopus 로고    scopus 로고
    • Imaging of persistent cAMP signaling by internalized G protein-coupled receptors
    • Calebiro D, Nikolaev VO, Lohse MJ. Imaging of persistent cAMP signaling by internalized G protein-coupled receptors. J Mol Endocrinol. 2010;45(1):1-8.
    • (2010) J Mol Endocrinol , vol.45 , Issue.1 , pp. 1-8
    • Calebiro, D.1    Nikolaev, V.O.2    Lohse, M.J.3
  • 115
    • 84924877730 scopus 로고    scopus 로고
    • GPCR signaling via heterotrimeric G proteins from endosomes
    • Tsvetanova NG, Irannejad R, von Zastrow M. GPCR signaling via heterotrimeric G proteins from endosomes. J Biol Chem. 2015;290:6689-6696.
    • (2015) J Biol Chem , vol.290 , pp. 6689-6696
    • Tsvetanova, N.G.1    Irannejad, R.2    Von Zastrow, M.3
  • 116
    • 84875604499 scopus 로고    scopus 로고
    • Conformational biosensors reveal GPCR signalling from endosomes
    • Irannejad R, Tomshine JC, Tomshine JR, et al. Conformational biosensors reveal GPCR signalling from endosomes. Nature. 2013;495(7442):534-538.
    • (2013) Nature , vol.495 , Issue.7442 , pp. 534-538
    • Irannejad, R.1    Tomshine, J.C.2    Tomshine, J.R.3
  • 117
    • 84875607396 scopus 로고    scopus 로고
    • Cell biology: Receptor signals come in waves
    • Lohse MJ, Calebiro D. Cell biology: receptor signals come in waves. Nature. 2013;495(7442):457-458.
    • (2013) Nature , vol.495 , Issue.7442 , pp. 457-458
    • Lohse, M.J.1    Calebiro, D.2
  • 118
    • 84922480357 scopus 로고    scopus 로고
    • Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis
    • Tsvetanova NG, von Zastrow M. Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis. Nat Chem Biol. 2014;10(12):1061-1065.
    • (2014) Nat Chem Biol , vol.10 , Issue.12 , pp. 1061-1065
    • Tsvetanova, N.G.1    Von Zastrow, M.2
  • 119
    • 41149180568 scopus 로고    scopus 로고
    • Endocytosis machinery is required for beta1-adrenergic receptor-induced hypertrophy in neonatal rat cardiac myocytes
    • Morisco C, Marrone C, Galeotti J, et al. Endocytosis machinery is required for beta1-adrenergic receptor-induced hypertrophy in neonatal rat cardiac myocytes. Cardiovasc Res. 2008;78(1):36-44.
    • (2008) Cardiovasc Res , vol.78 , Issue.1 , pp. 36-44
    • Morisco, C.1    Marrone, C.2    Galeotti, J.3
  • 120
    • 0030680131 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of betaarrestin1
    • Lin FT, Krueger KM, Kendall HE, et al. Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of betaarrestin1. J Biol Chem. 1997;272(49):31051-31057.
    • (1997) J Biol Chem , vol.272 , Issue.49 , pp. 31051-31057
    • Lin, F.T.1    Krueger, K.M.2    Kendall, H.E.3
  • 121
    • 0029061324 scopus 로고
    • Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor
    • Koch WJ, Rockman HA, Samama P, et al. Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science. 1995; 268(5215):1350-1353.
    • (1995) Science , vol.268 , Issue.5215 , pp. 1350-1353
    • Koch, W.J.1    Rockman, H.A.2    Samama, P.3
  • 122
    • 0028986859 scopus 로고
    • Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization
    • Pippig S, Andexinger S, Lohse MJ. Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization. Mol Pharmacol. 1995;47(4):666-676.
    • (1995) Mol Pharmacol , vol.47 , Issue.4 , pp. 666-676
    • Pippig, S.1    Andexinger, S.2    Lohse, M.J.3
  • 123
    • 35748944113 scopus 로고    scopus 로고
    • Ubiquitination of beta-arrestin links seventransmembrane receptor endocytosis and ERK activation
    • Shenoy SK, Barak LS, Xiao K, et al. Ubiquitination of beta-arrestin links seventransmembrane receptor endocytosis and ERK activation. J Biol Chem. 2007; 282(40):29549-29562.
    • (2007) J Biol Chem , vol.282 , Issue.40 , pp. 29549-29562
    • Shenoy, S.K.1    Barak, L.S.2    Xiao, K.3
  • 124
    • 0031975838 scopus 로고    scopus 로고
    • Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
    • Daaka Y, Luttrell LM, Ahn S, et al. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J Biol Chem. 1998;273(2):685-688.
    • (1998) J Biol Chem , vol.273 , Issue.2 , pp. 685-688
    • Daaka, Y.1    Luttrell, L.M.2    Ahn, S.3
  • 125
    • 84891467843 scopus 로고    scopus 로고
    • GPCR signaling along the endocytic pathway
    • Irannejad R, von Zastrow M. GPCR signaling along the endocytic pathway. Curr Opin Cell Biol. 2014;27:109-116.
    • (2014) Curr Opin Cell Biol , vol.27 , pp. 109-116
    • Irannejad, R.1    Von Zastrow, M.2
  • 126
    • 0033613938 scopus 로고    scopus 로고
    • Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
    • Luttrell LM, Ferguson SS, Daaka Y, et al. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999;283(5402):655-661.
    • (1999) Science , vol.283 , Issue.5402 , pp. 655-661
    • Luttrell, L.M.1    Ferguson, S.S.2    Daaka, Y.3
  • 127
    • 8144222927 scopus 로고    scopus 로고
    • Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes
    • Terrillon S, Bouvier M. Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes. EMBO J. 2004;23(20):3950-3961.
    • (2004) EMBO J , vol.23 , Issue.20 , pp. 3950-3961
    • Terrillon, S.1    Bouvier, M.2
  • 128
    • 0033527663 scopus 로고    scopus 로고
    • Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
    • Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J Biol Chem. 1999;274(45):32248-32257.
    • (1999) J Biol Chem , vol.274 , Issue.45 , pp. 32248-32257
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Barak, L.S.4    Caron, M.G.5
  • 129
    • 0034689003 scopus 로고    scopus 로고
    • Beta-arrestindependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
    • DeFea KA, Zalevsky J, Thoma MS, Dery O, Mullins RD, Bunnett NW. beta-arrestindependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol. 2000;148(6):1267-1281.
    • (2000) J Cell Biol , vol.148 , Issue.6 , pp. 1267-1281
    • DeFea, K.A.1    Zalevsky, J.2    Thoma, M.S.3    Dery, O.4    Mullins, R.D.5    Bunnett, N.W.6
  • 130
    • 0034718604 scopus 로고    scopus 로고
    • The proliferative and anti apoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex
    • DeFea KA, Vaughn ZD, O'Bryan EM, Nishijima D, Dery O, Bunnett NW. The proliferative and anti apoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex. Proc Natl Acad Sci USA. 2000; 97(20):11086-11091.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.20 , pp. 11086-11091
    • DeFea, K.A.1    Vaughn, Z.D.2    O'Bryan, E.M.3    Nishijima, D.4    Dery, O.5    Bunnett, N.W.6
  • 131
    • 84855901533 scopus 로고    scopus 로고
    • Molecular mechanism of beta-arrestinbiased agonism at seven-transmembrane receptors
    • Reiter E, Ahn S, Shukla AK, Lefkowitz RJ. Molecular mechanism of beta-arrestinbiased agonism at seven-transmembrane receptors. Annu Rev Pharmacol Toxicol. 2012;52:179-197.
    • (2012) Annu Rev Pharmacol Toxicol , vol.52 , pp. 179-197
    • Reiter, E.1    Ahn, S.2    Shukla, A.K.3    Lefkowitz, R.J.4
  • 132
    • 36749094552 scopus 로고    scopus 로고
    • A unique mechanism of beta-blocker action: Carvedilol stimulates beta-arrestin signaling
    • Wisler JW, DeWire SM, Whalen EJ, et al. A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling. Proc Natl Acad Sci USA. 2007;104(42):16657-16662.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.42 , pp. 16657-16662
    • Wisler, J.W.1    DeWire, S.M.2    Whalen, E.J.3
  • 133
    • 34848820302 scopus 로고    scopus 로고
    • Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection
    • Noma T, Lemaire A, Naga Prasad SV, et al. Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. J Clin Invest. 2007;117(9):2445-2458.
    • (2007) J Clin Invest , vol.117 , Issue.9 , pp. 2445-2458
    • Noma, T.1    Lemaire, A.2    Naga Prasad, S.V.3
  • 134
    • 0242637601 scopus 로고    scopus 로고
    • What is the role of beta-adrenergic signaling in heart failure?
    • Lohse MJ, Engelhardt S, Eschenhagen T. What is the role of beta-adrenergic signaling in heart failure? Circ Res. 2003;93(10):896-906.
    • (2003) Circ Res , vol.93 , Issue.10 , pp. 896-906
    • Lohse, M.J.1    Engelhardt, S.2    Eschenhagen, T.3
  • 135
    • 0027528961 scopus 로고
    • Overexpression of beta-arrestin and betaadrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors
    • Pippig S, Andexinger S, Daniel K, et al. Overexpression of beta-arrestin and betaadrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors. J Biol Chem. 1993;268(5):3201-3208.
    • (1993) J Biol Chem , vol.268 , Issue.5 , pp. 3201-3208
    • Pippig, S.1    Andexinger, S.2    Daniel, K.3
  • 136
    • 0031036520 scopus 로고    scopus 로고
    • The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification
    • Krueger KM, Daaka Y, Pitcher JA, Lefkowitz RJ. The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification. J Biol Chem. 1997;272(1):5-8.
    • (1997) J Biol Chem , vol.272 , Issue.1 , pp. 5-8
    • Krueger, K.M.1    Daaka, Y.2    Pitcher, J.A.3    Lefkowitz, R.J.4
  • 137
    • 0031603730 scopus 로고    scopus 로고
    • I1PP2A and I2PP2A. Two potent protein phosphatase 2A-specific inhibitor proteins
    • Li M, Damuni Z. I1PP2A and I2PP2A. Two potent protein phosphatase 2A-specific inhibitor proteins. Methods Mol Biol. 1998;93:59-66.
    • (1998) Methods Mol Biol , vol.93 , pp. 59-66
    • Li, M.1    Damuni, Z.2
  • 138
    • 79952674323 scopus 로고    scopus 로고
    • Inhibition of protein phosphatase 2A activity by PI3Kgamma regulates beta-adrenergic receptor function
    • Vasudevan NT, Mohan ML, Gupta MK, Hussain AK, Naga Prasad SV. Inhibition of protein phosphatase 2A activity by PI3Kgamma regulates beta-adrenergic receptor function. Mol Cell. 2011;41(6):636-648.
    • (2011) Mol Cell , vol.41 , Issue.6 , pp. 636-648
    • Vasudevan, N.T.1    Mohan, M.L.2    Gupta, M.K.3    Hussain, A.K.4    Naga Prasad, S.V.5
  • 139
    • 78650265725 scopus 로고    scopus 로고
    • Regulation of GPCR signal networks via membrane trafficking
    • Jean-Alphonse F, Hanyaloglu AC. Regulation of GPCR signal networks via membrane trafficking. Mol Cell Endocrinol. 2011;331(2):205-214.
    • (2011) Mol Cell Endocrinol , vol.331 , Issue.2 , pp. 205-214
    • Jean-Alphonse, F.1    Hanyaloglu, A.C.2
  • 140
    • 71749113078 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation
    • Namkung Y, Dipace C, Urizar E, Javitch JA, Sibley DR. G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation. J Biol Chem. 2009;284(49):34103-34115.
    • (2009) J Biol Chem , vol.284 , Issue.49 , pp. 34103-34115
    • Namkung, Y.1    Dipace, C.2    Urizar, E.3    Javitch, J.A.4    Sibley, D.R.5
  • 141
    • 66349083804 scopus 로고    scopus 로고
    • Cargo-mediated regulation of a rapid Rab4-dependent recycling pathway
    • Yudowski GA, Puthenveedu MA, Henry AG, von Zastrow M. Cargo-mediated regulation of a rapid Rab4-dependent recycling pathway. Mol Biol Cell. 2009; 20(11):2774-2784.
    • (2009) Mol Biol Cell , vol.20 , Issue.11 , pp. 2774-2784
    • Yudowski, G.A.1    Puthenveedu, M.A.2    Henry, A.G.3    Von Zastrow, M.4
  • 142
    • 33745744494 scopus 로고    scopus 로고
    • Distinct modes of regulated receptor insertion to the somatodendritic plasma membrane
    • Yudowski GA, Puthenveedu MA, von Zastrow M. Distinct modes of regulated receptor insertion to the somatodendritic plasma membrane. Nat Neurosci. 2006; 9(5):622-627.
    • (2006) Nat Neurosci , vol.9 , Issue.5 , pp. 622-627
    • Yudowski, G.A.1    Puthenveedu, M.A.2    Von Zastrow, M.3
  • 143
    • 58249102214 scopus 로고    scopus 로고
    • G-protein-coupled receptor-associated A-kinase anchoring proteins AKAP5 and AKAP12: Differential signaling to MAPK and GPCR recycling
    • Tao J, Malbon CC. G-protein-coupled receptor-associated A-kinase anchoring proteins AKAP5 and AKAP12: differential signaling to MAPK and GPCR recycling. J Mol Signal. 2008;3:19.
    • (2008) J Mol Signal , vol.3 , pp. 19
    • Tao, J.1    Malbon, C.C.2
  • 144
    • 33947547544 scopus 로고    scopus 로고
    • Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta 1)-adrenergic receptor generates a receptosome involved in receptor recycling and networking
    • Gardner LA, Naren AP, Bahouth SW. Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta(1)-adrenergic receptor generates a receptosome involved in receptor recycling and networking. J Biol Chem. 2007;282(7):5085-5099.
    • (2007) J Biol Chem , vol.282 , Issue.7 , pp. 5085-5099
    • Gardner, L.A.1    Naren, A.P.2    Bahouth, S.W.3
  • 146
    • 4944256731 scopus 로고    scopus 로고
    • GPCR-GIP networks: A first step in the discovery of new therapeutic drugs?
    • Bockaert J, Dumuis A, Fagni L, Marin P. GPCR-GIP networks: a first step in the discovery of new therapeutic drugs? Curr Opin Drug Discov Devel. 2004;7(5):649-657.
    • (2004) Curr Opin Drug Discov Devel , vol.7 , Issue.5 , pp. 649-657
    • Bockaert, J.1    Dumuis, A.2    Fagni, L.3    Marin, P.4
  • 147
    • 13544253361 scopus 로고    scopus 로고
    • Type i PDZ ligands are sufficient to promote rapid recycling of G Protein-coupled receptors independent of binding to N-ethylmaleimide-sensitive factor
    • Gage RM, Matveeva EA, Whiteheart SW, von Zastrow M. Type I PDZ ligands are sufficient to promote rapid recycling of G Protein-coupled receptors independent of binding to N-ethylmaleimide-sensitive factor. J Biol Chem. 2005;280(5):3305-3313.
    • (2005) J Biol Chem , vol.280 , Issue.5 , pp. 3305-3313
    • Gage, R.M.1    Matveeva, E.A.2    Whiteheart, S.W.3    Von Zastrow, M.4
  • 148
    • 0035977027 scopus 로고    scopus 로고
    • A transplantable sorting signal that is sufficient to mediate rapid recycling of G protein-coupled receptors
    • Gage RM, Kim KA, Cao TT, von Zastrow M. A transplantable sorting signal that is sufficient to mediate rapid recycling of G protein-coupled receptors. J Biol Chem. 2001;276(48):44712-44720.
    • (2001) J Biol Chem , vol.276 , Issue.48 , pp. 44712-44720
    • Gage, R.M.1    Kim, K.A.2    Cao, T.T.3    Von Zastrow, M.4
  • 149
    • 0033005974 scopus 로고    scopus 로고
    • Regulation of cortical structure by the ezrin-radixin-moesin protein family
    • Bretscher A. Regulation of cortical structure by the ezrin-radixin-moesin protein family. Curr Opin Cell Biol. 1999;11(1):109-116.
    • (1999) Curr Opin Cell Biol , vol.11 , Issue.1 , pp. 109-116
    • Bretscher, A.1
  • 150
    • 59049089795 scopus 로고    scopus 로고
    • Engineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by Hrs
    • Lauffer BE, Chen S, Melero C, Kortemme T, von Zastrow M, Vargas GA. Engineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by Hrs. J Biol Chem. 2009;284(4):2448-2458.
    • (2009) J Biol Chem , vol.284 , Issue.4 , pp. 2448-2458
    • Lauffer, B.E.1    Chen, S.2    Melero, C.3    Kortemme, T.4    Von Zastrow, M.5    Vargas, G.A.6
  • 151
    • 77955866103 scopus 로고    scopus 로고
    • SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane
    • Lauffer BE, Melero C, Temkin P, et al. SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane. J Cell Biol. 2010;190(4):565-574.
    • (2010) J Cell Biol , vol.190 , Issue.4 , pp. 565-574
    • Lauffer, B.E.1    Melero, C.2    Temkin, P.3
  • 152
    • 33646346138 scopus 로고    scopus 로고
    • Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins
    • He J, Bellini M, Inuzuka H, et al. Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins. J Biol Chem. 2006;281(5):2820-2827.
    • (2006) J Biol Chem , vol.281 , Issue.5 , pp. 2820-2827
    • He, J.1    Bellini, M.2    Inuzuka, H.3
  • 153
    • 0038383458 scopus 로고    scopus 로고
    • Regulated endocytosis of opioid receptors: Cellular mechanisms and proposed roles in physiological adaptation to opiate drugs
    • von Zastrow M, Svingos A, Haberstock-Debic H, Evans C. Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs. Curr Opin Neurobiol. 2003;13(3):348-353.
    • (2003) Curr Opin Neurobiol , vol.13 , Issue.3 , pp. 348-353
    • Von Zastrow, M.1    Svingos, A.2    Haberstock-Debic, H.3    Evans, C.4
  • 154
    • 35748970461 scopus 로고    scopus 로고
    • Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) mediates post-endocytic trafficking of protease-activated receptor 2 and calcitonin receptor-like receptor
    • Hasdemir B, Bunnett NW, Cottrell GS. Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) mediates post-endocytic trafficking of protease-activated receptor 2 and calcitonin receptor-like receptor. J Biol Chem. 2007; 282(40):29646-29657.
    • (2007) J Biol Chem , vol.282 , Issue.40 , pp. 29646-29657
    • Hasdemir, B.1    Bunnett, N.W.2    Cottrell, G.S.3
  • 155
    • 0242384217 scopus 로고    scopus 로고
    • Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway
    • von Zastrow M. Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway. Life Sci. 2003;74(2-3):217-224.
    • (2003) Life Sci , vol.74 , Issue.2-3 , pp. 217-224
    • Von Zastrow, M.1
  • 156
    • 0035252096 scopus 로고    scopus 로고
    • Role of endocytosis in mediating downregulation of G-protein-coupled receptors
    • Tsao P, Cao T, von Zastrow M. Role of endocytosis in mediating downregulation of G-protein-coupled receptors. Trends Pharmacol Sci. 2001;22(2):91-96.
    • (2001) Trends Pharmacol Sci , vol.22 , Issue.2 , pp. 91-96
    • Tsao, P.1    Cao, T.2    Von Zastrow, M.3
  • 157
    • 0038487327 scopus 로고    scopus 로고
    • The ins and outs of G protein-coupled receptor trafficking
    • Marchese A, Chen C, Kim YM, Benovic JL. The ins and outs of G protein-coupled receptor trafficking. Trends Biochem Sci. 2003;28(7):369-376.
    • (2003) Trends Biochem Sci , vol.28 , Issue.7 , pp. 369-376
    • Marchese, A.1    Chen, C.2    Kim, Y.M.3    Benovic, J.L.4
  • 158
    • 0035213859 scopus 로고    scopus 로고
    • Agonist-stimulated and tonic internalization of metabotropic glutamate receptor 1a in human embryonic kidney 293 cells: Agonist-stimulated endocytosis is beta-arrestin1 isoform-specific
    • Dale LB, Bhattacharya M, Seachrist JL, Anborgh PH, Ferguson SS. Agonist-stimulated and tonic internalization of metabotropic glutamate receptor 1a in human embryonic kidney 293 cells: agonist-stimulated endocytosis is beta-arrestin1 isoform-specific. Mol Pharmacol. 2001;60(6):1243-1253.
    • (2001) Mol Pharmacol , vol.60 , Issue.6 , pp. 1243-1253
    • Dale, L.B.1    Bhattacharya, M.2    Seachrist, J.L.3    Anborgh, P.H.4    Ferguson, S.S.5
  • 159
    • 0032582534 scopus 로고    scopus 로고
    • Separate signals for agonist-independent and agonisttriggered trafficking of protease-activated receptor 1
    • Shapiro MJ, Coughlin SR. Separate signals for agonist-independent and agonisttriggered trafficking of protease-activated receptor 1. J Biol Chem. 1998;273(44): 29009-29014.
    • (1998) J Biol Chem , vol.273 , Issue.44 , pp. 29009-29014
    • Shapiro, M.J.1    Coughlin, S.R.2
  • 161
    • 0035793059 scopus 로고    scopus 로고
    • Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus
    • Barak LS, Oakley RH, Laporte SA, Caron MG. Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus. Proc Natl Acad Sci USA. 2001;98(1):93-98.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.1 , pp. 93-98
    • Barak, L.S.1    Oakley, R.H.2    Laporte, S.A.3    Caron, M.G.4
  • 162
    • 0036898466 scopus 로고    scopus 로고
    • Constitutive activation and endocytosis of the complement factor 5a receptor: Evidence for multiple activated conformations of a G protein-coupled receptor
    • Whistler JL, Gerber BO, Meng EC, Baranski TJ, von Zastrow M, Bourne HR. Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor. Traffic. 2002;3(12):866-877.
    • (2002) Traffic , vol.3 , Issue.12 , pp. 866-877
    • Whistler, J.L.1    Gerber, B.O.2    Meng, E.C.3    Baranski, T.J.4    Von Zastrow, M.5    Bourne, H.R.6
  • 163
    • 84862902356 scopus 로고    scopus 로고
    • The role of endocytosis in activating and regulating signal transduction
    • Andersson ER. The role of endocytosis in activating and regulating signal transduction. Cell Mol Life Sci. 2012;69(11):1755-1771.
    • (2012) Cell Mol Life Sci , vol.69 , Issue.11 , pp. 1755-1771
    • Andersson, E.R.1
  • 165
    • 34447649922 scopus 로고    scopus 로고
    • Beta-arrestin-biased ligands at seven-transmembrane receptors
    • Violin JD, Lefkowitz RJ. Beta-arrestin-biased ligands at seven-transmembrane receptors. Trends Pharmacol Sci. 2007;28(8):416-422.
    • (2007) Trends Pharmacol Sci , vol.28 , Issue.8 , pp. 416-422
    • Violin, J.D.1    Lefkowitz, R.J.2
  • 166
    • 77951844975 scopus 로고    scopus 로고
    • Teaching old receptors new tricks: Biasing seven-transmembrane receptors
    • Rajagopal S, Rajagopal K, Lefkowitz RJ. Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nat Rev Drug Discov. 2010;9(5):373-386.
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.5 , pp. 373-386
    • Rajagopal, S.1    Rajagopal, K.2    Lefkowitz, R.J.3
  • 167
    • 33644857279 scopus 로고    scopus 로고
    • Beta-arrestin-dependent, G proteinindependent ERK1/2 activation by the beta2 adrenergic receptor
    • Shenoy SK, Drake MT, Nelson CD, et al. beta-arrestin-dependent, G proteinindependent ERK1/2 activation by the beta2 adrenergic receptor. J Biol Chem. 2006;281(2):1261-1273.
    • (2006) J Biol Chem , vol.281 , Issue.2 , pp. 1261-1273
    • Shenoy, S.K.1    Drake, M.T.2    Nelson, C.D.3
  • 168
    • 0034737730 scopus 로고    scopus 로고
    • Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart
    • Yue TL, Wang C, Gu JL, et al. Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart. Circ Res. 2000;86(6):692-699.
    • (2000) Circ Res , vol.86 , Issue.6 , pp. 692-699
    • Yue, T.L.1    Wang, C.2    Gu, J.L.3
  • 169
    • 11144358069 scopus 로고    scopus 로고
    • MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo
    • Lips DJ, Bueno OF, Wilkins BJ, et al. MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo. Circulation. 2004;109(16):1938-1941.
    • (2004) Circulation , vol.109 , Issue.16 , pp. 1938-1941
    • Lips, D.J.1    Bueno, O.F.2    Wilkins, B.J.3
  • 171
    • 51649084026 scopus 로고    scopus 로고
    • Antagonism of dopamine D2 receptor/betaarrestin 2 interaction is a common property of clinically effective antipsychotics
    • Masri B, Salahpour A, Didriksen M, et al. Antagonism of dopamine D2 receptor/betaarrestin 2 interaction is a common property of clinically effective antipsychotics. Proc Natl Acad Sci USA. 2008;105(36):13656-13661.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.36 , pp. 13656-13661
    • Masri, B.1    Salahpour, A.2    Didriksen, M.3
  • 172
    • 34147164933 scopus 로고    scopus 로고
    • Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics
    • Gonzalez-Cabrera PJ, Hla T, Rosen H. Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics. J Biol Chem. 2007;282(10):7254-7264.
    • (2007) J Biol Chem , vol.282 , Issue.10 , pp. 7254-7264
    • Gonzalez-Cabrera, P.J.1    Hla, T.2    Rosen, H.3
  • 173
    • 34447624153 scopus 로고    scopus 로고
    • Collateral efficacy in drug discovery: Taking advantage of the good (allosteric) nature of 7TM receptors
    • Kenakin T. Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors. Trends Pharmacol Sci. 2007;28(8):407-415.
    • (2007) Trends Pharmacol Sci , vol.28 , Issue.8 , pp. 407-415
    • Kenakin, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.