-
1
-
-
0034464742
-
Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
-
Gether, U. (2000) Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr. Rev. 21, 90-113
-
(2000)
Endocr. Rev.
, vol.21
, pp. 90-113
-
-
Gether, U.1
-
2
-
-
0035083109
-
Inverse, protean, and ligandselective agonism: Matters of receptor conformation
-
Kenakin, T. (2001) Inverse, protean, and ligandselective agonism: matters of receptor conformation. FASEB J. 15, 598-611
-
(2001)
FASEB J.
, vol.15
, pp. 598-611
-
-
Kenakin, T.1
-
3
-
-
0036177114
-
Drug efficacy at G protein-coupled receptors
-
Kenakin, T. (2002) Drug efficacy at G protein-coupled receptors. Annu. Rev. Pharmacol. Toxicol. 42, 349-379
-
(2002)
Annu. Rev. Pharmacol. Toxicol.
, vol.42
, pp. 349-379
-
-
Kenakin, T.1
-
4
-
-
0025212680
-
1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function
-
1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function. Proc. Natl. Acad. Sci. U. S. A. 87,2896-2900
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 2896-2900
-
-
Cotecchia, S.1
-
5
-
-
0035170508
-
Collecting and harvesting biological data: The GPCRDB and NucleaRDB information systems
-
Horn, F. et al. (2001) Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems. Nucleic Acids Res, 29, 346-349
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 346-349
-
-
Horn, F.1
-
6
-
-
0001169515
-
Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins
-
Costa, T. and Herz, A. (1989) Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins. Proc. Natl. Acad. Sci. U. S. A. 86, 7321-7325
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 7321-7325
-
-
Costa, T.1
Herz, A.2
-
7
-
-
0026592357
-
1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation
-
1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation. J. Biol. Chem. 267, 1430-1433
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1430-1433
-
-
Kjelsberg, M.A.1
-
8
-
-
0027298812
-
Constitutive activation of opsin: Influence of charge at position 134 and size at position 296
-
Cohen, G.B. et al. (1993) Constitutive activation of opsin: influence of charge at position 134 and size at position 296. Biochemistry 32, 6111-6115
-
(1993)
Biochemistry
, vol.32
, pp. 6111-6115
-
-
Cohen, G.B.1
-
9
-
-
0028061193
-
A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin
-
Arnis, S. et al. (1994)A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin. J. Biol. Chem. 269, 23879-23881
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23879-23881
-
-
Arnis, S.1
-
10
-
-
0029897495
-
1B-adrenergic receptor: Role of highly conserved polar amino acids in receptor activation
-
1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation. EMBO J. 15, 3566-3578
-
(1996)
EMBO J.
, vol.15
, pp. 3566-3578
-
-
Scheer, A.1
-
11
-
-
0030614337
-
1B-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate
-
1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate. Proc. Natl. Acad. Sci. U. S. A. 94, 808-813
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 808-813
-
-
Scheer, A.1
-
12
-
-
0033061256
-
2-adrenergic receptor: Constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6
-
2-adrenergic receptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6. Mol. Pharmacol. 56, 175-184
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 175-184
-
-
Rasmussen, S.G.1
-
13
-
-
0035800850
-
2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6
-
2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6. J. Biol. Chem. 276, 29171-29177
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29171-29177
-
-
Ballesteros, J.A.1
-
14
-
-
0032562699
-
Functional microdomains in G protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor
-
Ballesteros, J. et al. (1998) Functional microdomains in G protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor. J. Biol. Chem. 273, 10445-10453
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10445-10453
-
-
Ballesteros, J.1
-
15
-
-
0031037632
-
The role of the aspartate-arginine-tyrosine triad in the ml muscarinic receptor: Mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling
-
Lu, Z.L. et al. (1997) The role of the aspartate-arginine-tyrosine triad in the ml muscarinic receptor: mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling. Mol. Pharmacol. 51, 234-241
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 234-241
-
-
Lu, Z.L.1
-
16
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski, K. et al. (2000) Crystal structure of rhodopsin: A G protein-coupled receptor. Science 289, 739-745
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
-
17
-
-
0032474444
-
Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6
-
Han, M. et al. (1998) Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6. Biochemistry 37, 8253-8261
-
(1998)
Biochemistry
, vol.37
, pp. 8253-8261
-
-
Han, M.1
-
18
-
-
0030614507
-
111 in the third transmembrane domain of the AT1A angiotensin II receptor induces its constitutive activation
-
111 in the third transmembrane domain of the AT1A angiotensin II receptor induces its constitutive activation. J. Biol. Chem. 272, 1822-1826
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1822-1826
-
-
Groblewski, T.1
-
19
-
-
0031041454
-
The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII
-
Balmforth, A.J. et al. (1997) The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII. J. Biol. Chem. 272, 4245-4251
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4245-4251
-
-
Balmforth, A.J.1
-
20
-
-
0032239841
-
Review: Amino acid domains involved in constitutive activation of G protein-coupled receptors
-
Pauwels, P.J. and Wurch, T. (1998) Review: amino acid domains involved in constitutive activation of G protein-coupled receptors. Mol. Neurobiol. 17, 109-135
-
(1998)
Mol. Neurobiol.
, vol.17
, pp. 109-135
-
-
Pauwels, P.J.1
Wurch, T.2
-
21
-
-
0037040202
-
The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constrain the transmembrane region: Studies using chimeric human and fly receptors
-
Nishi, S. et al. (2002) The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constrain the transmembrane region: studies using chimeric human and fly receptors. J. Biol. Chem. 277, 3958-3964
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3958-3964
-
-
Nishi, S.1
-
22
-
-
0029963929
-
Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity
-
Prezeau, L. et al. (1996) Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity. Mol. Pharmacol. 49, 422-429
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 422-429
-
-
Prezeau, L.1
-
23
-
-
0032555649
-
Identification of a ligand-dependent switch within a muscarinic receptor
-
Spalding, T.A. et al. (1998) Identification of a ligand-dependent switch within a muscarinic receptor. J. Biol. Chem. 273, 21563-21568
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21563-21568
-
-
Spalding, T.A.1
-
24
-
-
0032544633
-
The second intracellular loop of the m5 muscarinic receptor is the switch which enables G protein coupling
-
Burstein, E.S. et al. (1998) The second intracellular loop of the m5 muscarinic receptor is the switch which enables G protein coupling. J. Biol. Chem. 273, 24322-24327
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24322-24327
-
-
Burstein, E.S.1
-
25
-
-
0035957579
-
Constitutively active muscarinic receptors
-
Spalding, T.A. and Burstein, E.S. (2001) Constitutively active muscarinic receptors. Life Sci. 68, 2511-2516
-
(2001)
Life Sci.
, vol.68
, pp. 2511-2516
-
-
Spalding, T.A.1
Burstein, E.S.2
-
26
-
-
0034691035
-
Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay
-
Parnot, C. et al. (2000) Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay. Proc. Natl. Acad. Sci. U. S. A. 97, 7615-7620
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 7615-7620
-
-
Parnot, C.1
-
27
-
-
0035824582
-
1B-adrenergic receptor. Involvement of basic and hydrophobic residues in receptor activation and G protein coupling
-
1B-adrenergic receptor. Involvement of basic and hydrophobic residues in receptor activation and G protein coupling. J. Biol. Chem. 276, 46485-46494
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46485-46494
-
-
Greasley, P.J.1
-
28
-
-
0034634690
-
Genetic mapping of the human C5A receptor. Identification of transmembrane amino acids critical for receptor function
-
Geva, A. et al. (2000) Genetic mapping of the human C5A receptor. Identification of transmembrane amino acids critical for receptor function. J. Biol. Chem. 275, 35393-35401
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35393-35401
-
-
Geva, A.1
-
29
-
-
0031724218
-
Identification of a polar region in transmembrane domain 6 that regulates the function of the G protein-coupled α-factor receptor
-
Dube, P. and Konopka, J.B. (1998) Identification of a polar region in transmembrane domain 6 that regulates the function of the G protein-coupled α-factor receptor. Mol. Cell. Biol. 18, 7205-7215
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7205-7215
-
-
Dube, P.1
Konopka, J.B.2
-
30
-
-
0036190987
-
The cytoplasmic end of transmembrane domain 3 regulates the activity of the Saccharomyces cerevisiae G protein-coupled α-factor receptor
-
Parrish, W. et al. (2002) The cytoplasmic end of transmembrane domain 3 regulates the activity of the Saccharomyces cerevisiae G protein-coupled α-factor receptor. Genetics 160, 429-443
-
(2002)
Genetics
, vol.160
, pp. 429-443
-
-
Parrish, W.1
-
31
-
-
0031018485
-
Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility
-
Gether, U. et al. (1997) Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility. J. Biol. Chem. 272, 2587-2590
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2587-2590
-
-
Gether, U.1
-
32
-
-
0033049565
-
1B-adrenergic receptor mutants display different phosphorylation and internalization features
-
1B-adrenergic receptor mutants display different phosphorylation and internalization features. Mol. Pharmacol. 55, 339-347
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 339-347
-
-
Mhaouty-Kodja, S.1
-
33
-
-
0034723193
-
Agonist-induced phosphorylation of the angiotensin II (AT(1A)) receptor requires generation of a conformation that is distinct from the inositol phosphatesignaling state
-
Thomas, W.G. et al. (2000)Agonist-induced phosphorylation of the angiotensin II (AT(1A)) receptor requires generation of a conformation that is distinct from the inositol phosphatesignaling state. J. Biol. Chem. 275, 2893-2900
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2893-2900
-
-
Thomas, W.G.1
-
34
-
-
0030991648
-
Constitutive activation of the cyclic adenosine 3′,5′-monophosphate signaling pathway by parathyroid hormone (PTH)/PTH-related peptide receptors mutated at the two loci for Jansen's metaphyseal chondrodysplasia
-
Schipani, E. et al. (1997) Constitutive activation of the cyclic adenosine 3′,5′-monophosphate signaling pathway by parathyroid hormone (PTH)/PTH-related peptide receptors mutated at the two loci for Jansen's metaphyseal chondrodysplasia. Mol. Endocrinol. 11, 851-858
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 851-858
-
-
Schipani, E.1
-
35
-
-
0033580648
-
Molecular characterization of the receptor-ligand complex for parathyroid hormone
-
Rolz, C. et al. (1999) Molecular characterization of the receptor-ligand complex for parathyroid hormone. Biochemistry 38, 6397-6405
-
(1999)
Biochemistry
, vol.38
, pp. 6397-6405
-
-
Rolz, C.1
-
36
-
-
0035049091
-
Selective and nonselective inverse agonists for constitutively active type-1 parathyroid hormone receptors: Evidence for altered receptor conformations
-
Carter, P.H. et al. (2001) Selective and nonselective inverse agonists for constitutively active type-1 parathyroid hormone receptors: evidence for altered receptor conformations. Endocrinology 142, 1534-1545
-
(2001)
Endocrinology
, vol.142
, pp. 1534-1545
-
-
Carter, P.H.1
-
37
-
-
0035101820
-
Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
-
Ferguson, S.S. (2001) Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol. Rev. 53, 1-24
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 1-24
-
-
Ferguson, S.S.1
-
38
-
-
0032567352
-
Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the lutropin/choriogonadotropin receptor
-
Min, K.S. et al. (1998) Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the lutropin/choriogonadotropin receptor. J. Biol. Chem. 273, 34911-34919
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34911-34919
-
-
Min, K.S.1
-
39
-
-
0033645593
-
Effect of activating and inactivating mutations on the phosphorylation and trafficking of the human lutropin/choriogonadotropin receptor
-
Min, L. and Ascoli, M. (2000) Effect of activating and inactivating mutations on the phosphorylation and trafficking of the human lutropin/choriogonadotropin receptor. Mol. Endocrinol. 14, 1797-1810
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1797-1810
-
-
Min, L.1
Ascoli, M.2
-
40
-
-
0028331771
-
2-adrenergic receptor is constitutively desensitized and phosphorylated
-
2-adrenergic receptor is constitutively desensitized and phosphorylated. Proc. Natl. Acad. Sci. U. S. A. 91, 2699-2702
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 2699-2702
-
-
Pei, G.1
-
41
-
-
0037155153
-
Constitutive internalization of constitutively active angiotensin II AT(1A) receptor mutants is blocked by inverse agonists
-
Miserey-Lenkei, S. et al. (2002) Constitutive internalization of constitutively active angiotensin II AT(1A) receptor mutants is blocked by inverse agonists. J. Biol. Chem. 277, 5891-5901
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5891-5901
-
-
Miserey-Lenkei, S.1
-
42
-
-
0030478939
-
Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization
-
Shapiro, M.J. et al. (1996) Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization. J. Biol. Chem. 271, 32874-32880
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32874-32880
-
-
Shapiro, M.J.1
-
43
-
-
0030995508
-
Visualization of G protein-coupled receptor trafficking with the aid of the green fluorescent protein. Endocytosis and recycling of cholecystokinin receptor type A
-
Tarasova, N.I. et al. (1997) Visualization of G protein-coupled receptor trafficking with the aid of the green fluorescent protein. Endocytosis and recycling of cholecystokinin receptor type A. J. Biol. Chem. 272, 14817-14824
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14817-14824
-
-
Tarasova, N.I.1
-
44
-
-
0028886577
-
A constitutively active mutant thyrotropin-releasing hormone receptor is chronically down-regulated in pituitary cells: Evidence using chlordiazepoxide as a negative antagonist
-
Heinflink, M. et al. (1995) A constitutively active mutant thyrotropin-releasing hormone receptor is chronically down-regulated in pituitary cells: evidence using chlordiazepoxide as a negative antagonist. Mol. Endocrinol. 9, 1455-1460
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 1455-1460
-
-
Heinflink, M.1
-
45
-
-
0030752182
-
1B-adrenoceptor by ligands that act as inverse agonists
-
1B-adrenoceptor by ligands that act as inverse agonists. Biochem. J. 325, 733-739
-
(1997)
Biochem. J.
, vol.325
, pp. 733-739
-
-
Lee, T.W.1
-
47
-
-
0029948346
-
Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors
-
Smit, M.J. et al. (1996) Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors. Proc. Natl. Acad. Sci. U. S. A. 93, 6802-6807
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 6802-6807
-
-
Smit, M.J.1
-
48
-
-
0031941108
-
Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors
-
Stefan, C.J. et al. (1998) Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors. Mol. Biol. Cell 9, 885-899
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 885-899
-
-
Stefan, C.J.1
-
49
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
Parma, J. et al. (1993) Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature 365, 649-651
-
(1993)
Nature
, vol.365
, pp. 649-651
-
-
Parma, J.1
-
50
-
-
0027372340
-
A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty
-
Shenker, A. et al. (1993) A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty. Nature 365, 652-654
-
(1993)
Nature
, vol.365
, pp. 652-654
-
-
Shenker, A.1
-
51
-
-
0029913238
-
An activating mutation of the follicle-stimulating hormone receptor autonomously sustains spermatogenesis in a hypophysectomized man
-
Gromoll, J. et al. (1996) An activating mutation of the follicle-stimulating hormone receptor autonomously sustains spermatogenesis in a hypophysectomized man. J. Clin. Endocrinol. Metab. 81, 1367-1370
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 1367-1370
-
-
Gromoll, J.1
-
52
-
-
0028125886
-
Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness
-
Rao, VR. et al. (1994) Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness. Nature 367, 639-642
-
(1994)
Nature
, vol.367
, pp. 639-642
-
-
Rao, V.R.1
-
53
-
-
0028943780
-
A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia
-
Schipani, E. et al. (1995)A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science 268, 98-100
-
(1995)
Science
, vol.268
, pp. 98-100
-
-
Schipani, E.1
-
54
-
-
0029796174
-
The calcium-sensing receptor: A window into the physiology and pathophysiology of mineral ion metabolism
-
Chattopadhyay, N. et al. (1996) The calcium-sensing receptor: a window into the physiology and pathophysiology of mineral ion metabolism. Endocr Rev. 17, 289-307
-
(1996)
Endocr. Rev.
, vol.17
, pp. 289-307
-
-
Chattopadhyay, N.1
-
55
-
-
0031737430
-
Melanocortin receptor 1 (MC1R) mutations and coat color in pigs
-
Kijas, J.M. et al. (1998) Melanocortin receptor 1 (MC1R) mutations and coat color in pigs. Genetics 150, 1177-1185
-
(1998)
Genetics
, vol.150
, pp. 1177-1185
-
-
Kijas, J.M.1
-
56
-
-
0034118221
-
Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants
-
Morello, J.P. et al. (2000) Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants. J. Clin. Invest. 105, 887-895
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 887-895
-
-
Morello, J.P.1
-
57
-
-
0031032245
-
Somatic mutations of the angiotensin II (AT1) receptor gene are not present in aldosterone-producing adenoma
-
Davies, E. et al. (1997) Somatic mutations of the angiotensin II (AT1) receptor gene are not present in aldosterone-producing adenoma. J. Clin. Endocrinol. Metab. 82, 611-615
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 611-615
-
-
Davies, E.1
-
58
-
-
0031442990
-
Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide
-
Schipani, E. et al. (1997) Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide. Proc. Natl. Acad. Sci. U. S. A. 94, 13689-13694
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13689-13694
-
-
Schipani, E.1
-
59
-
-
0027940368
-
1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy
-
1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy. Proc. Natl. Acad. Sci. U. S. A. 91, 10109-10113
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 10109-10113
-
-
Milano, C.A.1
-
60
-
-
0031031054
-
2-adrenergic receptor: Pharmacological creation of a phenotype in transgenic mice
-
2-adrenergic receptor: pharmacological creation of a phenotype in transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 94, 137-141
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 137-141
-
-
Samama, P.1
-
61
-
-
0035903243
-
1A-adrenergic receptor overexpression induces enhanced cardiac contractility but not hypertrophy
-
1A-adrenergic receptor overexpression induces enhanced cardiac contractility but not hypertrophy. Circ. Res. 89, 343-350
-
(2001)
Circ. Res.
, vol.89
, pp. 343-350
-
-
Lin, F.1
-
62
-
-
0034891574
-
1B-adrenergic receptor induces dilated cardiomyopathy
-
1B-adrenergic receptor induces dilated cardiomyopathy. Am. J. Physiol. 281, H931-938
-
(2001)
Am. J. Physiol.
, vol.281
-
-
Lemire, I.1
-
64
-
-
0028987954
-
2-adrenoceptor
-
2-adrenoceptor. Nature 374, 272-276
-
(1995)
Nature
, vol.374
, pp. 272-276
-
-
Bond, R.A.1
-
65
-
-
0030610246
-
Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block
-
Hein, L. et al. (1997) Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block. Proc. Natl. Acad. Sci. U. S. A. 94, 6391-6396
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 6391-6396
-
-
Hein, L.1
-
66
-
-
0022536710
-
Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains
-
Young, D. et al. (1986) Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains. Cell 45, 711-719
-
(1986)
Cell
, vol.45
, pp. 711-719
-
-
Young, D.1
-
67
-
-
0026318020
-
1B-adrenergic receptor enhances mitogenesis and tumorigenicity
-
1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proc. Natl. Acad. Sci. U. S. A. 88, 11354-11358
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 11354-11358
-
-
Allen, L.F.1
-
68
-
-
0031937076
-
G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
-
Bais, C. et al. (1998) G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 391, 86-89
-
(1998)
Nature
, vol.391
, pp. 86-89
-
-
Bais, C.1
-
69
-
-
0031913524
-
Activating smoothened mutations in sporadic basal-cell carcinoma
-
Xie, J. et al. (1998) Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature 391, 90-92
-
(1998)
Nature
, vol.391
, pp. 90-92
-
-
Xie, J.1
-
70
-
-
0030960824
-
Human calcitonin receptors exhibit agonist-independent (constitutive) signaling activity
-
Cohen, D.P. et al. (1997) Human calcitonin receptors exhibit agonist-independent (constitutive) signaling activity. Endocrinology 138, 1400-1405
-
(1997)
Endocrinology
, vol.138
, pp. 1400-1405
-
-
Cohen, D.P.1
|