Phosphoinositide 3-kinase regulates β2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/β-arrestin complex

Journal of Cell Biology

Volumn 158, Issue 3, 2002, Pages 563-575

  Naga Prasad, Sathyamangla V ^a   Laporte, Stéphane A ^a   Chamberlain, Dean ^a   Caron, Marc G ^a   Barak, Larry ^a   Rockman, Howard A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

adrenergic receptor; AP 2; Endocytosis; Phosphatidylinositols; Phosphoinositide 3 kinase

Indexed keywords

ADAPTOR PROTEIN; BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN; CLATHRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TRANSCRIPTION FACTOR AP 2; TRANSFERRIN; TRANSFERRIN RECEPTOR;

ARTICLE; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEIN COMPLEX DELTA SUBUNITS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ADRENERGIC BETA-AGONISTS; ARRESTINS; BETA-ADRENERGIC RECEPTOR KINASE; CARRIER PROTEINS; CELL MEMBRANE; CELLS, CULTURED; CLATHRIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOCYTOSIS; EUKARYOTIC CELLS; GENE EXPRESSION; HUMANS; ISOPROTERENOL; MEMBRANE PROTEINS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PTEN PHOSPHOHYDROLASE; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; TRANSFECTION; TRANSFERRIN; TUMOR SUPPRESSOR PROTEINS;

EID: 0036327388     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200202113     Document Type: Article

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