An acylation cycle regulates localization and activity of palmitoylated ras isoforms

Science

Volumn 307, Issue 5716, 2005, Pages 1746-1752

  Rocks, Oliver ^a,b   Peyker, Anna ^b   Kahms, Martin ^a   Verveer, Peter J ^b   Koerner, Carolin ^a   Lumbierres, Maria ^a   Kuhlmann, Jürgen ^a   Waldmann, Herbert ^a   Wittinghofer, Alfred ^a   Bastiaens, Philippe I H ^b  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ACYLATION; GROWTH KINETICS; PROTEINS; TRANSPORT PROPERTIES;

GOLGI APPARATUS; PALMITOYLATED RAS ISOFORMS; PLASMA MEMBRANE (PM); SUBCELLULAR DISTRIBUTION;

CELL MEMBRANES;

BINDING PROTEIN; ISOPROTEIN; PROTEIN HRAS GUANOSINE TRIPHOSPHATE; PROTEIN HRAS GUANOSINE TRIPHOSPHATE BINDING PROTEIN; PROTEIN NRAS GUANOSINE TRIPHOSPHATE; PROTEIN NRAS GUANOSINE TRIPHOSPHATE BINDING PROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG;

BIOLOGY;

ACYLATION; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT;

ACYLATION; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; DOGS; GOLGI APPARATUS; GUANOSINE TRIPHOSPHATE; KINETICS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PALMITIC ACID; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS P21(RAS); RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 20144375061     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1105654     Document Type: Article

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