Palmitoylation regulates intracellular trafficking of β2 adrenergic receptor/arrestin/phosphodiesterase 4D complexes in cardiomyocytes

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Liu, Ruijie ^a   Wang, Dayong ^a   Shi, Qian ^a   Fu, Qin ^a   Hizon, Steven ^a   Xiang, Yang K ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ARRESTIN 2; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTEINE; DYNAMIN; PHOSPHODIESTERASE 4D; PHOSPHODIESTERASE IV; UNCLASSIFIED DRUG;

ACYLATION; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAVEOLA; CELL MIGRATION; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVITY; HEART CONTRACTION; HEART MUSCLE CELL; INTERNALIZATION; INTRACELLULAR SIGNALING; MOUSE; NEWBORN; NONHUMAN; PALMITOYLATION; PHARMACOLOGICAL STIMULATION; POINT MUTATION; PROTEIN LOCALIZATION; REGULATORY MECHANISM;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ANIMALS; ARRESTIN; BASAL METABOLISM; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; INTRACELLULAR SPACE; ISOENZYMES; LIPOYLATION; MICE; MUSCLE CONTRACTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; SPATIO-TEMPORAL ANALYSIS;

EID: 84864978744     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042658     Document Type: Article

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