Mechanisms of β-Adrenergic Receptor Desensitization and Resensitization

Advances in Pharmacology

Volumn 42, Issue C, 1997, Pages 416-420

  Lefkowitz, Robert J ^a   Pitcher, Julie ^a   Krueger, Kathleen ^a   Daaka, Yehia ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0344310763     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60777-2     Document Type: Article

References (5)

1. Inglese J., Freedman N.J., Koch W., and Lefkowitz R.J. Structure and mechanism of the G protein-coupled receptor kinases. J. Biol. Chem 268 (1993) 23735-23738
2. Premont R.T., Inglese J., and Lefkowitz R.J. Protein kinases that phosphorylate activated G protein-coupled receptors. FASEB J 9 (1995) 176-182
3. Pitcher J.A., Touhara K., Payne E.S., and Lefkowitz R.J. Pleckstrin homology domain-mediated membrane association and activation of the β-adrenergic receptor kinase requires coordinate interaction with Gβγ subunits and lipid. J. Biol. Chem. 270 (1995) 11707-11710
4. Pitcher J.A., Payne E.S., Csortos C., DePaoli-Roach A.A., and Lefkowitz R.J. The G protein-coupled receptor phosphatase: A protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 8343-8347
5. Krueger K.K., Daaka Y., Pitcher J.A., and Lefkowitz R.J. The role of sequestration in G protein-coupled receptor resensitization: Regulation of β 2-adrenergic receptor dephosphorylation by vesicular acidification. J. Biol. Chem 272 (1997) 5-8