Restoration of β-adrenergic receptor signaling and contractile function in heart failure by disruption of the βARKl/phosphoinositide 3-kinase complex

Circulation

Volumn 111, Issue 20, 2005, Pages 2579-2587

  Perrino, Cinzia ^a   Prasad, Sathyamangla V Naga ^a   Schroder, Jacob N ^a   Hata, Jonathan A ^a   Milano, Carmelo ^a   Rockman, Howard A ^a,b  

^a DUKE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Catecholamines; Gene therapy; Heart failure; Receptors, adrenergic, beta

Indexed keywords

BETA ADRENERGIC RECEPTOR; ISOPRENALINE; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DESENSITIZATION; ENDOSOME; ENZYME ACTIVITY; GENE TRANSFER; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SWINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; ENDOSOMES; GENE THERAPY; HEART FAILURE, CONGESTIVE; ISOPROTERENOL; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION; SWINE;

EID: 19644397920     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.104.508796     Document Type: Article

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