Insulin inhibits cardiac contractility by inducing a Gi-Biased β2-adrenergic signaling in hearts

Diabetes

Volumn 63, Issue 8, 2014, Pages 2676-2689

  Fu, Qin ^a,b,c   Xu, Bing ^a   Liu, Yongming ^a,d   Parikh, Dippal ^a   Li, Jing ^e   Li, Ying ^e   Zhang, Yuan ^f,g   Riehle, Christian ^f,g   Zhu, Yi ^f   Rawlings, Tenley ^f   Shi, Qian ^a,c   Clark, Richard B ^h   Chen, Xiongwen ^e   Abel, E Dale ^f,g   Xiang, Yang K ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d SHUGUANG HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^e TEMPLE UNIVERSITY HOSPITAL   (United States)

^f UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF IOWA   (United States)

^h UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; G-PROTEIN-COUPLED RECEPTOR KINASE 2; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MICE; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION;

EID: 84904994548     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1763     Document Type: Article

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