β-arrestin-biased agonism at the β2-adrenergic receptor

Journal of Biological Chemistry

Volumn 283, Issue 9, 2008, Pages 5669-5676

  Drake, Matthew T ^a,b   Violin, Jonathan D ^a   Whalen, Erin J ^a   Wisler, James W ^a   Shenoy, Sudha K ^a   Lefkowitz, Robert J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b Mayo Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; ARGON; ENERGY TRANSFER; ENZYME INHIBITION; FLUORESCENCE;

ADRENERGIC RECEPTORS; AGONISM; ARRESTIN; ARRESTINS; CYCLIC AMPS; FLUORESCENCE RESONANCE ENERGY TRANSFERS; G PROTEIN ACTIVATIONS; G PROTEINS; HIGHLY SENSITIVES; MEMBRANE TRANSLOCATIONS; RECEPTOR ACTIVITIES; SIGNALING PATHWAYS; STRUCTURAL COMPARISONS; TRANSMEMBRANE RECEPTORS;

LIGANDS;

BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN; ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; RETINA S ANTIGEN;

ARTICLE; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; CELL LINE; CELL MEMBRANE; CHEMISTRY; DRUG EFFECT; DRUG POTENTIATION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

ADRENERGIC AGONISTS; ARRESTINS; CELL LINE; CELL MEMBRANE; CYCLIC AMP; FLUORESCENCE RESONANCE ENERGY TRANSFER; GTP-BINDING PROTEINS; HUMANS; LIGANDS; PROTEIN TRANSPORT; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION;

EID: 41949089470     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708118200     Document Type: Article

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