-
1
-
-
84902271945
-
Functional roles of the sweet taste receptor in oral and extraoral tissues
-
COI: 1:CAS:528:DC%2BC2cXpsVelt70%3D, PID: 2476306
-
Laffitte A, Neiers F, Briand L. Functional roles of the sweet taste receptor in oral and extraoral tissues. Curr Opin Clin Nutr Metab Care. 2014;17(4):379–85.
-
(2014)
Curr Opin Clin Nutr Metab Care
, vol.17
, Issue.4
, pp. 379-385
-
-
Laffitte, A.1
Neiers, F.2
Briand, L.3
-
2
-
-
84870314938
-
Extraoral bitter taste receptors as mediators of off-target drug effects
-
COI: 1:CAS:528:DC%2BC38XhvVCgtrjM, PID: 2296430
-
Clark AA, Liggett SB, Munger SD. Extraoral bitter taste receptors as mediators of off-target drug effects. FASEB J. 2012;26(12):4827–31.
-
(2012)
FASEB J
, vol.26
, Issue.12
, pp. 4827-4831
-
-
Clark, A.A.1
Liggett, S.B.2
Munger, S.D.3
-
3
-
-
84889637546
-
Taste receptors of the gut: emerging roles in health and disease
-
COI: 1:CAS:528:DC%2BC2cXit12htro%3D, PID: 2413163
-
Depoortere I. Taste receptors of the gut: emerging roles in health and disease. Gut. 2014;63(1):179–90.
-
(2014)
Gut
, vol.63
, Issue.1
, pp. 179-190
-
-
Depoortere, I.1
-
4
-
-
77957739610
-
Oral and extraoral bitter taste receptors
-
COI: 1:CAS:528:DC%2BC3cXhtlKgsb3F, PID: 2086537
-
Behrens M, Meyerhof W. Oral and extraoral bitter taste receptors. Results Probl Cell Differ. 2010;52:87–99.
-
(2010)
Results Probl Cell Differ
, vol.52
, pp. 87-99
-
-
Behrens, M.1
Meyerhof, W.2
-
5
-
-
84855357959
-
Taste receptor signalling—from tongues to lungs
-
COI: 1:CAS:528:DC%2BC38Xht1eitbo%3
-
Kinnamon SC. Taste receptor signalling—from tongues to lungs. Acta Physiol (Oxf). 2012;204(2):158–68.
-
(2012)
Acta Physiol (Oxf)
, vol.204
, Issue.2
, pp. 158-168
-
-
Kinnamon, S.C.1
-
6
-
-
38049129559
-
Enteroendocrine cells: a site of ‘taste’ in gastrointestinal chemosensing
-
COI: 1:CAS:528:DC%2BD1cXitFKgs74%3D, PID: 1818506
-
Sternini C, Anselmi L, Rozengurt E. Enteroendocrine cells: a site of ‘taste’ in gastrointestinal chemosensing. Curr Opin Endocrinol Diabetes Obes. 2008;15(1):73–8.
-
(2008)
Curr Opin Endocrinol Diabetes Obes
, vol.15
, Issue.1
, pp. 73-78
-
-
Sternini, C.1
Anselmi, L.2
Rozengurt, E.3
-
7
-
-
77649260272
-
Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals
-
COI: 1:CAS:528:DC%2BC3cXis1CgtLg%3D, PID: 20133764, Demonstrated that bitter taste receptors are used to detect bacterial products in the airway
-
Tizzano M et al. Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals. Proc Natl Acad Sci U S A. 2010;107(7):3210–5. Demonstrated that bitter taste receptors are used to detect bacterial products in the airway.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.7
, pp. 3210-3215
-
-
Tizzano, M.1
-
8
-
-
84868610108
-
T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection
-
COI: 1:CAS:528:DC%2BC38Xhs1CisL%2FL, PID: 23041624, Experiment to demonstrate the T2R38 stimulation causes downstream production of NO with subsequent increased MCC and bacterial killing
-
Lee RJ et al. T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J Clin Invest. 2012;122(11):4145–59. Experiment to demonstrate the T2R38 stimulation causes downstream production of NO with subsequent increased MCC and bacterial killing.
-
(2012)
J Clin Invest
, vol.122
, Issue.11
, pp. 4145-4159
-
-
Lee, R.J.1
-
9
-
-
0037423367
-
Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways
-
COI: 1:CAS:528:DC%2BD3sXhtlCmsLc%3D, PID: 1258152
-
Zhang Y et al. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Cell. 2003;112(3):293–301.
-
(2003)
Cell
, vol.112
, Issue.3
, pp. 293-301
-
-
Zhang, Y.1
-
10
-
-
84903696086
-
Taste transductions in taste receptor cells: basic tastes and moreover
-
COI: 1:CAS:528:DC%2BC2cXpt1WhtrY%3D, PID: 2388638
-
Iwata S, Yoshida R, Ninomiya Y. Taste transductions in taste receptor cells: basic tastes and moreover. Curr Pharm Des. 2014;20(16):2684–92.
-
(2014)
Curr Pharm Des
, vol.20
, Issue.16
, pp. 2684-2692
-
-
Iwata, S.1
Yoshida, R.2
Ninomiya, Y.3
-
11
-
-
0037016771
-
Molecular mechanisms of bitter and sweet taste transduction
-
COI: 1:CAS:528:DC%2BD38XjslCksw%3D%3D, PID: 1169655
-
Margolskee RF. Molecular mechanisms of bitter and sweet taste transduction. J Biol Chem. 2002;277(1):1–4.
-
(2002)
J Biol Chem
, vol.277
, Issue.1
, pp. 1-4
-
-
Margolskee, R.F.1
-
12
-
-
80053460282
-
The functional role of the T1R family of receptors in sweet taste and feeding
-
COI: 1:CAS:528:DC%2BC3MXht1Kmtr7M, PID: 2137606
-
Treesukosol Y, Smith KR, Spector AC. The functional role of the T1R family of receptors in sweet taste and feeding. Physiol Behav. 2011;105(1):14–26.
-
(2011)
Physiol Behav
, vol.105
, Issue.1
, pp. 14-26
-
-
Treesukosol, Y.1
Smith, K.R.2
Spector, A.C.3
-
13
-
-
0034677653
-
A novel family of mammalian taste receptors
-
COI: 1:CAS:528:DC%2BD3cXitFeks7o%3D, PID: 1076193
-
Adler E et al. A novel family of mammalian taste receptors. Cell. 2000;100(6):693–702.
-
(2000)
Cell
, vol.100
, Issue.6
, pp. 693-702
-
-
Adler, E.1
-
14
-
-
34547802810
-
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium
-
COI: 1:CAS:528:DC%2BD2sXmvV2qsbw%3D, PID: 1759510
-
Brockhoff A et al. Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium. J Agric Food Chem. 2007;55(15):6236–43.
-
(2007)
J Agric Food Chem
, vol.55
, Issue.15
, pp. 6236-6243
-
-
Brockhoff, A.1
-
15
-
-
0034677655
-
T2Rs function as bitter taste receptors
-
COI: 1:CAS:528:DC%2BD3cXitFeks7s%3D, PID: 1076193
-
Chandrashekar J et al. T2Rs function as bitter taste receptors. Cell. 2000;100(6):703–11.
-
(2000)
Cell
, vol.100
, Issue.6
, pp. 703-711
-
-
Chandrashekar, J.1
-
16
-
-
25144464874
-
Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat
-
COI: 1:CAS:528:DC%2BD2MXpvFOltrk%3D, PID: 1588633
-
Wu SV, Chen MC, Rozengurt E. Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat. Physiol Genomics. 2005;22(2):139–49.
-
(2005)
Physiol Genomics
, vol.22
, Issue.2
, pp. 139-149
-
-
Wu, S.V.1
Chen, M.C.2
Rozengurt, E.3
-
17
-
-
84895487775
-
Peripheral coding of taste
-
COI: 1:CAS:528:DC%2BC2cXjslyisbw%3D, PID: 2460722
-
Liman ER, Zhang YV, Montell C. Peripheral coding of taste. Neuron. 2014;81(5):984–1000.
-
(2014)
Neuron
, vol.81
, Issue.5
, pp. 984-1000
-
-
Liman, E.R.1
Zhang, Y.V.2
Montell, C.3
-
18
-
-
84873431549
-
Taste buds as peripheral chemosensory processors
-
COI: 1:CAS:528:DC%2BC3sXntFykug%3D%3D, PID: 2326195
-
Roper SD. Taste buds as peripheral chemosensory processors. Semin Cell Dev Biol. 2013;24(1):71–9.
-
(2013)
Semin Cell Dev Biol
, vol.24
, Issue.1
, pp. 71-79
-
-
Roper, S.D.1
-
19
-
-
77950114281
-
The molecular receptive ranges of human TAS2R bitter taste receptors
-
COI: 1:CAS:528:DC%2BC3cXnsVSqsg%3D%3D, PID: 2002291
-
Meyerhof W et al. The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses. 2010;35(2):157–70.
-
(2010)
Chem Senses
, vol.35
, Issue.2
, pp. 157-170
-
-
Meyerhof, W.1
-
20
-
-
0034721781
-
Targeted phosphorylation of inositol 1,4,5-trisphosphate receptors selectively inhibits localized Ca2+ release and shapes oscillatory Ca2+ signals
-
COI: 1:CAS:528:DC%2BD3cXnvVyjsbo%3D, PID: 1088719
-
Giovannucci DR et al. Targeted phosphorylation of inositol 1,4,5-trisphosphate receptors selectively inhibits localized Ca2+ release and shapes oscillatory Ca2+ signals. J Biol Chem. 2000;275(43):33704–11.
-
(2000)
J Biol Chem
, vol.275
, Issue.43
, pp. 33704-33711
-
-
Giovannucci, D.R.1
-
21
-
-
84867778180
-
Genetic labeling of Tas1r1 and Tas2r131 taste receptor cells in mice
-
COI: 1:CAS:528:DC%2BC38XhsFGit73L, PID: 2301079
-
Voigt A et al. Genetic labeling of Tas1r1 and Tas2r131 taste receptor cells in mice. Chem Senses. 2012;37(9):897–911.
-
(2012)
Chem Senses
, vol.37
, Issue.9
, pp. 897-911
-
-
Voigt, A.1
-
22
-
-
84880681249
-
Taste perception: from the tongue to the testis
-
COI: 1:CAS:528:DC%2BC3sXosVehs7g%3D, PID: 2342326
-
Li F. Taste perception: from the tongue to the testis. Mol Hum Reprod. 2013;19(6):349–60.
-
(2013)
Mol Hum Reprod
, vol.19
, Issue.6
, pp. 349-360
-
-
Li, F.1
-
23
-
-
84887619658
-
How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel
-
COI: 1:CAS:528:DC%2BC3sXhvVShsLjO, PID: 2410591
-
Taruno A et al. How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel. Bioessays. 2013;35(12):1111–8.
-
(2013)
Bioessays
, vol.35
, Issue.12
, pp. 1111-1118
-
-
Taruno, A.1
-
24
-
-
34250666600
-
The transduction channel TRPM5 is gated by intracellular calcium in taste cells
-
COI: 1:CAS:528:DC%2BD2sXmsVWnsLg%3D, PID: 1752232
-
Zhang Z et al. The transduction channel TRPM5 is gated by intracellular calcium in taste cells. J Neurosci. 2007;27(21):5777–86.
-
(2007)
J Neurosci
, vol.27
, Issue.21
, pp. 5777-5786
-
-
Zhang, Z.1
-
25
-
-
0035044181
-
IP(3) receptor type 3 and PLCbeta2 are co-expressed with taste receptors T1R and T2R in rat taste bud cells
-
COI: 1:STN:280:DC%2BD3M3ntFekug%3D%3D, PID: 1128738
-
Miyoshi MA, Abe K, Emori Y. IP(3) receptor type 3 and PLCbeta2 are co-expressed with taste receptors T1R and T2R in rat taste bud cells. Chem Senses. 2001;26(3):259–65.
-
(2001)
Chem Senses
, vol.26
, Issue.3
, pp. 259-265
-
-
Miyoshi, M.A.1
Abe, K.2
Emori, Y.3
-
26
-
-
84874956365
-
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes
-
COI: 1:CAS:528:DC%2BC3sXjvFejtLo%3D, PID: 2346709
-
Taruno A et al. CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature. 2013;495(7440):223–6.
-
(2013)
Nature
, vol.495
, Issue.7440
, pp. 223-226
-
-
Taruno, A.1
-
27
-
-
84863709168
-
Immunohistochemical detection of TAS2R38 protein in human taste cells
-
COI: 1:CAS:528:DC%2BC38XhtVCitLbF, PID: 2279227
-
Behrens M et al. Immunohistochemical detection of TAS2R38 protein in human taste cells. PLoS One. 2012;7(7), e40304.
-
(2012)
PLoS One
, vol.7
, Issue.7
-
-
Behrens, M.1
-
28
-
-
0014096826
-
The role of the respiratory mucosa in health and disease
-
COI: 1:STN:280:DyaF2s3ltFeltQ%3D%3D, PID: 604151
-
Hilding AC. The role of the respiratory mucosa in health and disease. Minn Med. 1967;50(6):915–9.
-
(1967)
Minn Med
, vol.50
, Issue.6
, pp. 915-919
-
-
Hilding, A.C.1
-
29
-
-
33646228394
-
Regional analysis of sinonasal ciliary beat frequency
-
PID: 1668637
-
Shaari J et al. Regional analysis of sinonasal ciliary beat frequency. Am J Rhinol. 2006;20(2):150–4.
-
(2006)
Am J Rhinol
, vol.20
, Issue.2
, pp. 150-154
-
-
Shaari, J.1
-
30
-
-
0023902304
-
The propulsion of mucus by cilia
-
COI: 1:STN:280:DyaL1c7kvVKjtQ%3D%3D, PID: 327866
-
Sleigh MA, Blake JR, Liron N. The propulsion of mucus by cilia. Am Rev Respir Dis. 1988;137(3):726–41.
-
(1988)
Am Rev Respir Dis
, vol.137
, Issue.3
, pp. 726-741
-
-
Sleigh, M.A.1
Blake, J.R.2
Liron, N.3
-
31
-
-
80051626877
-
Innate immunity in the respiratory epithelium
-
COI: 1:CAS:528:DC%2BC3MXhtVSitrrM, PID: 2133046
-
Parker D, Prince A. Innate immunity in the respiratory epithelium. Am J Respir Cell Mol Biol. 2011;45(2):189–201.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, Issue.2
, pp. 189-201
-
-
Parker, D.1
Prince, A.2
-
32
-
-
0036194724
-
Mucus clearance as a primary innate defense mechanism for mammalian airways
-
COI: 1:CAS:528:DC%2BD38XitVeqt78%3D, PID: 1187746
-
Knowles MR, Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest. 2002;109(5):571–7.
-
(2002)
J Clin Invest
, vol.109
, Issue.5
, pp. 571-577
-
-
Knowles, M.R.1
Boucher, R.C.2
-
33
-
-
39749095910
-
Innate immunity in the paranasal sinuses: a review of nasal host defenses
-
PID: 1828485
-
Ooi EH, Wormald PJ, Tan LW. Innate immunity in the paranasal sinuses: a review of nasal host defenses. Am J Rhinol. 2008;22(1):13–9.
-
(2008)
Am J Rhinol
, vol.22
, Issue.1
, pp. 13-19
-
-
Ooi, E.H.1
Wormald, P.J.2
Tan, L.W.3
-
34
-
-
0002958069
-
Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state
-
COI: 1:STN:280:DC%2BD3srgs1alsw%3D%3D, PID: 1168685
-
Hume DA et al. Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state. BMC Immunol. 2001;2:11.
-
(2001)
BMC Immunol
, vol.2
, pp. 11
-
-
Hume, D.A.1
-
35
-
-
84879700974
-
Solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosa
-
PID: 2340493
-
Barham HP et al. Solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosa. Int Forum Allergy Rhinol. 2013;3(6):450–7.
-
(2013)
Int Forum Allergy Rhinol
, vol.3
, Issue.6
, pp. 450-457
-
-
Barham, H.P.1
-
36
-
-
78651282172
-
Expression of taste receptors in solitary chemosensory cells of rodent airways
-
COI: 1:CAS:528:DC%2BC3MXht1Oht7g%3D, PID: 21232137, Analyzed the expression pattern of taste receptors in the rodent airway
-
Tizzano M et al. Expression of taste receptors in solitary chemosensory cells of rodent airways. BMC Pulm Med. 2011;11:3. Analyzed the expression pattern of taste receptors in the rodent airway.
-
(2011)
BMC Pulm Med
, vol.11
, pp. 3
-
-
Tizzano, M.1
-
37
-
-
84896770768
-
Bitter and sweet taste receptors regulate human upper respiratory innate immunity
-
COI: 1:CAS:528:DC%2BC2cXkt1Wrurs%3D, PID: 2453155
-
Lee RJ et al. Bitter and sweet taste receptors regulate human upper respiratory innate immunity. J Clin Invest. 2014;124(3):1393–405.
-
(2014)
J Clin Invest
, vol.124
, Issue.3
, pp. 1393-1405
-
-
Lee, R.J.1
-
38
-
-
69549084858
-
Motile cilia of human airway epithelia are chemosensory
-
COI: 1:CAS:528:DC%2BD1MXhtVersr%2FI, PID: 19628819, Seminal study demonstrating that cilia can detect chemicals in the sinonasal tract
-
Shah AS et al. Motile cilia of human airway epithelia are chemosensory. Science. 2009;325(5944):1131–4. Seminal study demonstrating that cilia can detect chemicals in the sinonasal tract.
-
(2009)
Science
, vol.325
, Issue.5944
, pp. 1131-1134
-
-
Shah, A.S.1
-
39
-
-
84899050450
-
Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation
-
COI: 1:CAS:528:DC%2BC2cXmtlWntL8%3D, PID: 24711432, Experiment to show that the SCC in the mouse transduces bitter taste signals into inflammatory responses
-
Saunders CJ et al. Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation. Proc Natl Acad Sci U S A. 2014;111(16):6075–80. Experiment to show that the SCC in the mouse transduces bitter taste signals into inflammatory responses.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.16
, pp. 6075-6080
-
-
Saunders, C.J.1
-
40
-
-
42149105016
-
Solitary chemoreceptor cell survival is independent of intact trigeminal innervation
-
PID: 1830026
-
Gulbransen B, Silver W, Finger TE. Solitary chemoreceptor cell survival is independent of intact trigeminal innervation. J Comp Neurol. 2008;508(1):62–71.
-
(2008)
J Comp Neurol
, vol.508
, Issue.1
, pp. 62-71
-
-
Gulbransen, B.1
Silver, W.2
Finger, T.E.3
-
41
-
-
33750479893
-
Involvement of nitric oxide in biofilm dispersal of Pseudomonas aeruginosa
-
COI: 1:CAS:528:DC%2BD28XhtFKjtLnK, PID: 1705092
-
Barraud N et al. Involvement of nitric oxide in biofilm dispersal of Pseudomonas aeruginosa. J Bacteriol. 2006;188(21):7344–53.
-
(2006)
J Bacteriol
, vol.188
, Issue.21
, pp. 7344-7353
-
-
Barraud, N.1
-
42
-
-
33947367829
-
Regulation of mammalian ciliary beating
-
COI: 1:CAS:528:DC%2BD2sXltVaksL0%3D, PID: 1694506
-
Salathe M. Regulation of mammalian ciliary beating. Annu Rev Physiol. 2007;69:401–22.
-
(2007)
Annu Rev Physiol
, vol.69
, pp. 401-422
-
-
Salathe, M.1
-
43
-
-
84879394923
-
Sesquiterpenoids lactones: benefits to plants and people
-
PID: 2378327
-
Chadwick M et al. Sesquiterpenoids lactones: benefits to plants and people. Int J Mol Sci. 2013;14(6):12780–805.
-
(2013)
Int J Mol Sci
, vol.14
, Issue.6
, pp. 12780-12805
-
-
Chadwick, M.1
-
44
-
-
84860539275
-
The multiple signaling systems regulating virulence in Pseudomonas aeruginosa
-
COI: 1:CAS:528:DC%2BC38XlslKisbw%3D, PID: 2239097
-
Jimenez PN et al. The multiple signaling systems regulating virulence in Pseudomonas aeruginosa. Microbiol Mol Biol Rev. 2012;76(1):46–65.
-
(2012)
Microbiol Mol Biol Rev
, vol.76
, Issue.1
, pp. 46-65
-
-
Jimenez, P.N.1
-
45
-
-
84866617309
-
Quorum sensing: how bacteria can coordinate activity and synchronize their response to external signals?
-
COI: 1:CAS:528:DC%2BC38XhtlKlt7nJ, PID: 2282585
-
Li Z, Nair SK. Quorum sensing: how bacteria can coordinate activity and synchronize their response to external signals? Protein Sci. 2012;21(10):1403–17.
-
(2012)
Protein Sci
, vol.21
, Issue.10
, pp. 1403-1417
-
-
Li, Z.1
Nair, S.K.2
-
46
-
-
0034254922
-
Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms
-
COI: 1:CAS:528:DC%2BD3cXls12lt7g%3D, PID: 1092203
-
Parsek MR, Greenberg EP. Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms. Proc Natl Acad Sci U S A. 2000;97(16):8789–93.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.16
, pp. 8789-8793
-
-
Parsek, M.R.1
Greenberg, E.P.2
-
47
-
-
0033407414
-
Alpha-gustducin expression in the vomeronasal organ of the mouse
-
COI: 1:STN:280:DC%2BD3c%2Fmt1GitQ%3D%3D, PID: 1059467
-
Zancanaro C et al. Alpha-gustducin expression in the vomeronasal organ of the mouse. Eur J Neurosci. 1999;11(12):4473–5.
-
(1999)
Eur J Neurosci
, vol.11
, Issue.12
, pp. 4473-4475
-
-
Zancanaro, C.1
-
48
-
-
35148856832
-
The solitary chemosensory cells and the diffuse chemosensory system of the airway
-
PID: 1770359
-
Osculati F et al. The solitary chemosensory cells and the diffuse chemosensory system of the airway. Eur J Histochem. 2007;51 Suppl 1:65–72.
-
(2007)
Eur J Histochem
, vol.51
, pp. 65-72
-
-
Osculati, F.1
-
49
-
-
61649093046
-
TRPM5-expressing microvillous cells in the main olfactory epithelium
-
PID: 1902563
-
Lin W et al. TRPM5-expressing microvillous cells in the main olfactory epithelium. BMC Neurosci. 2008;9:114.
-
(2008)
BMC Neurosci
, vol.9
, pp. 114
-
-
Lin, W.1
-
50
-
-
33745685286
-
Neuropeptide immunofluorescence in human nasal mucosa: assessment of the technique for vasoactive intestinal peptide (VIP)
-
PID: 1644690
-
Mendonca JC, Dolci JE. Neuropeptide immunofluorescence in human nasal mucosa: assessment of the technique for vasoactive intestinal peptide (VIP). Braz J Otorhinolaryngol. 2005;71(2):123–31.
-
(2005)
Braz J Otorhinolaryngol
, vol.71
, Issue.2
, pp. 123-131
-
-
Mendonca, J.C.1
Dolci, J.E.2
-
51
-
-
0027312746
-
Substance P, calcitonin gene-related peptide, and vasoactive intestinal peptide increase in nasal secretions after allergen challenge in atopic patients
-
COI: 1:STN:280:DyaK3szivV2rsA%3D%3D, PID: 768760
-
Mosimann BL et al. Substance P, calcitonin gene-related peptide, and vasoactive intestinal peptide increase in nasal secretions after allergen challenge in atopic patients. J Allergy Clin Immunol. 1993;92(1 Pt 1):95–104.
-
(1993)
J Allergy Clin Immunol
, vol.92
, pp. 95-104
-
-
Mosimann, B.L.1
-
52
-
-
84890535104
-
Vasoactive intestinal peptide regulates sinonasal mucociliary clearance and synergizes with histamine in stimulating sinonasal fluid secretion
-
COI: 1:CAS:528:DC%2BC3sXhvVOnsrbL, PID: 23934280, Experiment to show that the SCC in humans transduces bitter and sweet taste signals and show antimicrobial peptide secretory responses
-
Lee RJ et al. Vasoactive intestinal peptide regulates sinonasal mucociliary clearance and synergizes with histamine in stimulating sinonasal fluid secretion. FASEB J. 2013;27(12):5094–103. Experiment to show that the SCC in humans transduces bitter and sweet taste signals and show antimicrobial peptide secretory responses.
-
(2013)
FASEB J
, vol.27
, Issue.12
, pp. 5094-5103
-
-
Lee, R.J.1
-
53
-
-
84856576205
-
Solitary chemosensory cells in the respiratory and vomeronasal epithelium of the human nose: a pilot study
-
PID: 22125779, Identification of SCCs in the human sinonasal mucosa
-
Braun T, Mack B, Kramer MF. Solitary chemosensory cells in the respiratory and vomeronasal epithelium of the human nose: a pilot study. Rhinology. 2011;49(5):507–12. Identification of SCCs in the human sinonasal mucosa.
-
(2011)
Rhinology
, vol.49
, Issue.5
, pp. 507-512
-
-
Braun, T.1
Mack, B.2
Kramer, M.F.3
-
54
-
-
0041806520
-
Solitary chemoreceptor cells in the nasal cavity serve as sentinels of respiration
-
COI: 1:CAS:528:DC%2BD3sXlvVyiurg%3D, PID: 1285794
-
Finger TE et al. Solitary chemoreceptor cells in the nasal cavity serve as sentinels of respiration. Proc Natl Acad Sci U S A. 2003;100(15):8981–6.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.15
, pp. 8981-8986
-
-
Finger, T.E.1
-
55
-
-
79959346115
-
Cholinergic chemosensory cells in the trachea regulate breathing
-
COI: 1:CAS:528:DC%2BC3MXnslGhs7o%3D, PID: 2160635
-
Krasteva G et al. Cholinergic chemosensory cells in the trachea regulate breathing. Proc Natl Acad Sci U S A. 2011;108(23):9478–83.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.23
, pp. 9478-9483
-
-
Krasteva, G.1
-
56
-
-
84883200070
-
Chemosensory brush cells of the trachea. A stable population in a dynamic epithelium
-
COI: 1:CAS:528:DC%2BC3sXht1elt7%2FE, PID: 2352622
-
Saunders CJ, Reynolds SD, Finger TE. Chemosensory brush cells of the trachea. A stable population in a dynamic epithelium. Am J Respir Cell Mol Biol. 2013;49(2):190–6.
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, Issue.2
, pp. 190-196
-
-
Saunders, C.J.1
Reynolds, S.D.2
Finger, T.E.3
-
57
-
-
84865126124
-
TAS2R activation promotes airway smooth muscle relaxation despite beta(2)-adrenergic receptor tachyphylaxis
-
COI: 1:CAS:528:DC%2BC38XhtlSksr7E, PID: 22683571, Bitter taste receptor stimulation causes downstream bronchodilation
-
An SS et al. TAS2R activation promotes airway smooth muscle relaxation despite beta(2)-adrenergic receptor tachyphylaxis. Am J Physiol Lung Cell Mol Physiol. 2012;303(4):L304–11. Bitter taste receptor stimulation causes downstream bronchodilation.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
, Issue.4
, pp. L304-L311
-
-
An, S.S.1
-
58
-
-
78149355561
-
Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction
-
COI: 1:CAS:528:DC%2BC3cXhtlahu7rF, PID: 2097243
-
Deshpande DA et al. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nat Med. 2010;16(11):1299–304.
-
(2010)
Nat Med
, vol.16
, Issue.11
, pp. 1299-1304
-
-
Deshpande, D.A.1
-
59
-
-
84898727600
-
Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells
-
PID: 2421957
-
Robinett KS et al. Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells. Am J Respir Cell Mol Biol. 2014;50(4):678–83.
-
(2014)
Am J Respir Cell Mol Biol
, vol.50
, Issue.4
, pp. 678-683
-
-
Robinett, K.S.1
-
60
-
-
79951805645
-
Allelic variation in TAS2R bitter receptor genes associates with variation in sensations from and ingestive behaviors toward common bitter beverages in adults
-
COI: 1:CAS:528:DC%2BC3MXitlarurw%3D, PID: 2116391
-
Hayes JE et al. Allelic variation in TAS2R bitter receptor genes associates with variation in sensations from and ingestive behaviors toward common bitter beverages in adults. Chem Senses. 2011;36(3):311–9.
-
(2011)
Chem Senses
, vol.36
, Issue.3
, pp. 311-319
-
-
Hayes, J.E.1
-
61
-
-
13944250257
-
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception
-
COI: 1:CAS:528:DC%2BD2MXhsFSiu7k%3D, PID: 1572379
-
Bufe B et al. The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Curr Biol. 2005;15(4):322–7.
-
(2005)
Curr Biol
, vol.15
, Issue.4
, pp. 322-327
-
-
Bufe, B.1
-
62
-
-
15844424818
-
Genetics of individual differences in bitter taste perception: lessons from the PTC gene
-
COI: 1:CAS:528:DC%2BD2MXjtlartro%3D, PID: 1573326
-
Kim UK, Drayna D. Genetics of individual differences in bitter taste perception: lessons from the PTC gene. Clin Genet. 2005;67(4):275–80.
-
(2005)
Clin Genet
, vol.67
, Issue.4
, pp. 275-280
-
-
Kim, U.K.1
Drayna, D.2
-
63
-
-
84891595945
-
The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery
-
PID: 24302675, Prospective study demonstrating the increased need for FESS among AVI/AVI TAS2R38 genotype in CRS patients
-
Adappa ND et al. The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery. Int Forum Allergy Rhinol. 2014;4(1):3–7. Prospective study demonstrating the increased need for FESS among AVI/AVI TAS2R38 genotype in CRS patients.
-
(2014)
Int Forum Allergy Rhinol
, vol.4
, Issue.1
, pp. 3-7
-
-
Adappa, N.D.1
-
64
-
-
70350352914
-
Epithelium, cilia, and mucus: their importance in chronic rhinosinusitis
-
Antunes MB, Gudis DA, Cohen NA. Epithelium, cilia, and mucus: their importance in chronic rhinosinusitis. Immunol Allergy Clin N Am. 2009;29(4):631–43.
-
(2009)
Immunol Allergy Clin N Am
, vol.29
, Issue.4
, pp. 631-643
-
-
Antunes, M.B.1
Gudis, D.A.2
Cohen, N.A.3
-
65
-
-
0036695727
-
The effects of pneumolysin and hydrogen peroxide, alone and in combination, on human ciliated epithelium in vitro
-
COI: 1:STN:280:DC%2BD38vjvVWrtg%3D%3D, PID: 1219583
-
Feldman C et al. The effects of pneumolysin and hydrogen peroxide, alone and in combination, on human ciliated epithelium in vitro. Respir Med. 2002;96(8):580–5.
-
(2002)
Respir Med
, vol.96
, Issue.8
, pp. 580-585
-
-
Feldman, C.1
-
66
-
-
39049194566
-
Effects of staphylococcal enterotoxin on ciliary activity and histology of the sinus mucosa
-
COI: 1:CAS:528:DC%2BD28XhtVCmtrnP, PID: 1686449
-
Min YG et al. Effects of staphylococcal enterotoxin on ciliary activity and histology of the sinus mucosa. Acta Otolaryngol. 2006;126(9):941–7.
-
(2006)
Acta Otolaryngol
, vol.126
, Issue.9
, pp. 941-947
-
-
Min, Y.G.1
-
67
-
-
33746149026
-
Altered sinonasal ciliary dynamics in chronic rhinosinusitis
-
PID: 1687193
-
Chen B et al. Altered sinonasal ciliary dynamics in chronic rhinosinusitis. Am J Rhinol. 2006;20(3):325–9.
-
(2006)
Am J Rhinol
, vol.20
, Issue.3
, pp. 325-329
-
-
Chen, B.1
-
68
-
-
0242288486
-
Absorption enhancers for nasal drug delivery
-
COI: 1:CAS:528:DC%2BD3sXpsF2ls7s%3D, PID: 1453172
-
Davis SS, Illum L. Absorption enhancers for nasal drug delivery. Clin Pharmacokinet. 2003;42(13):1107–28.
-
(2003)
Clin Pharmacokinet
, vol.42
, Issue.13
, pp. 1107-1128
-
-
Davis, S.S.1
Illum, L.2
-
69
-
-
34548497194
-
Nitric oxide: a new concept in chronic sinusitis pathogenesis
-
COI: 1:CAS:528:DC%2BD2sXhtVWitb3N, PID: 1782653
-
Naraghi M et al. Nitric oxide: a new concept in chronic sinusitis pathogenesis. Am J Otolaryngol. 2007;28(5):334–7.
-
(2007)
Am J Otolaryngol
, vol.28
, Issue.5
, pp. 334-337
-
-
Naraghi, M.1
-
70
-
-
79959610799
-
Nasal nitric oxide and sinonasal disease: a systematic review of published evidence
-
PID: 2163405
-
Phillips PS et al. Nasal nitric oxide and sinonasal disease: a systematic review of published evidence. Otolaryngol Head Neck Surg. 2011;144(2):159–69.
-
(2011)
Otolaryngol Head Neck Surg
, vol.144
, Issue.2
, pp. 159-169
-
-
Phillips, P.S.1
-
71
-
-
84875042411
-
Genetics of the taste receptor T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention
-
PID: 23322450, T2R38 genotype determines necessity for surgical intervention in CRS
-
Adappa ND et al. Genetics of the taste receptor T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention. Int Forum Allergy Rhinol. 2013;3(3):184–7. T2R38 genotype determines necessity for surgical intervention in CRS.
-
(2013)
Int Forum Allergy Rhinol
, vol.3
, Issue.3
, pp. 184-187
-
-
Adappa, N.D.1
-
72
-
-
84895452125
-
Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study
-
PID: 24415641, Confirmation that T2R38 genotype is associated with CRS
-
Mfuna Endam L et al. Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study. Int Forum Allergy Rhinol. 2014;4(3):200–6. Confirmation that T2R38 genotype is associated with CRS.
-
(2014)
Int Forum Allergy Rhinol
, vol.4
, Issue.3
, pp. 200-206
-
-
Mfuna Endam, L.1
-
73
-
-
84883441174
-
The emerging role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis
-
PID: 2388380
-
Lee RJ, Cohen NA. The emerging role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis. Am J Rhinol Allergy. 2013;27(4):283–6.
-
(2013)
Am J Rhinol Allergy
, vol.27
, Issue.4
, pp. 283-286
-
-
Lee, R.J.1
Cohen, N.A.2
-
74
-
-
59849094422
-
Glucose homeostasis across human airway epithelial cell monolayers: role of diffusion, transport and metabolism
-
COI: 1:CAS:528:DC%2BD1MXhsFOnt78%3D, PID: 1878132
-
Kalsi KK et al. Glucose homeostasis across human airway epithelial cell monolayers: role of diffusion, transport and metabolism. Pflugers Arch. 2009;457(5):1061–70.
-
(2009)
Pflugers Arch
, vol.457
, Issue.5
, pp. 1061-1070
-
-
Kalsi, K.K.1
-
75
-
-
65649131584
-
Contribution of the T1r3 taste receptor to the response properties of central gustatory neurons
-
COI: 1:CAS:528:DC%2BD1MXmtVWqtbY%3D, PID: 1927915
-
Lemon CH, Margolskee RF. Contribution of the T1r3 taste receptor to the response properties of central gustatory neurons. J Neurophysiol. 2009;101(5):2459–71.
-
(2009)
J Neurophysiol
, vol.101
, Issue.5
, pp. 2459-2471
-
-
Lemon, C.H.1
Margolskee, R.F.2
-
76
-
-
17644389240
-
Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste
-
COI: 1:CAS:528:DC%2BD2MXjtFSlt7o%3D, PID: 1566825
-
Jiang P et al. Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste. J Biol Chem. 2005;280(15):15238–46.
-
(2005)
J Biol Chem
, vol.280
, Issue.15
, pp. 15238-15246
-
-
Jiang, P.1
-
77
-
-
77955493507
-
Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor
-
COI: 1:CAS:528:DC%2BC3cXotVChu7o%3D, PID: 2049382
-
Imada T et al. Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor. Biochem Biophys Res Commun. 2010;397(2):220–5.
-
(2010)
Biochem Biophys Res Commun
, vol.397
, Issue.2
, pp. 220-225
-
-
Imada, T.1
-
78
-
-
84903746597
-
Genetics of taste receptors
-
COI: 1:CAS:528:DC%2BC2cXpt1Wgtr4%3D, PID: 2388638
-
Bachmanov AA et al. Genetics of taste receptors. Curr Pharm Des. 2014;20(16):2669–83.
-
(2014)
Curr Pharm Des
, vol.20
, Issue.16
, pp. 2669-2683
-
-
Bachmanov, A.A.1
-
79
-
-
68149137765
-
Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose
-
COI: 1:CAS:528:DC%2BD1MXps1Crtrc%3D, PID: 1955961
-
Fushan AA et al. Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose. Curr Biol. 2009;19(15):1288–93.
-
(2009)
Curr Biol
, vol.19
, Issue.15
, pp. 1288-1293
-
-
Fushan, A.A.1
-
80
-
-
17844382462
-
Genetic and environmental determinants of bitter perception and sweet preferences
-
PID: 1568742
-
Mennella JA, Pepino MY, Reed DR. Genetic and environmental determinants of bitter perception and sweet preferences. Pediatrics. 2005;115(2):e216–22.
-
(2005)
Pediatrics
, vol.115
, Issue.2
, pp. e216-e222
-
-
Mennella, J.A.1
Pepino, M.Y.2
Reed, D.R.3
-
81
-
-
79251636742
-
Glucose depletion in the airway surface liquid is essential for sterility of the airways
-
COI: 1:CAS:528:DC%2BC3MXht1Ogtr8%3D, PID: 2131159
-
Pezzulo AA et al. Glucose depletion in the airway surface liquid is essential for sterility of the airways. PLoS One. 2011;6(1), e16166.
-
(2011)
PLoS One
, vol.6
, Issue.1
-
-
Pezzulo, A.A.1
-
82
-
-
84897379111
-
The effect of diabetes mellitus on chronic rhinosinusitis and sinus surgery outcome
-
PID: 2441555
-
Zhang Z et al. The effect of diabetes mellitus on chronic rhinosinusitis and sinus surgery outcome. Int Forum Allergy Rhinol. 2014;4(4):315–20.
-
(2014)
Int Forum Allergy Rhinol
, vol.4
, Issue.4
, pp. 315-320
-
-
Zhang, Z.1
-
83
-
-
84880170996
-
Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics
-
COI: 1:CAS:528:DC%2BC3sXht1Clu7jL, PID: 23222870, Asthmatics have an upregulation of bitter taste receptor expression
-
Orsmark-Pietras C et al. Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics. Eur Respir J. 2013;42(1):65–78. Asthmatics have an upregulation of bitter taste receptor expression.
-
(2013)
Eur Respir J
, vol.42
, Issue.1
, pp. 65-78
-
-
Orsmark-Pietras, C.1
-
84
-
-
78751653584
-
Reduction of disulphide bonds unmasks potent antimicrobial activity of human beta-defensin 1
-
COI: 1:CAS:528:DC%2BC3MXnvVKksg%3D%3D, PID: 2124885
-
Schroeder BO et al. Reduction of disulphide bonds unmasks potent antimicrobial activity of human beta-defensin 1. Nature. 2011;469(7330):419–23.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 419-423
-
-
Schroeder, B.O.1
-
85
-
-
84887989699
-
Antiviral mechanisms of human defensins
-
COI: 1:CAS:528:DC%2BC3sXhs1CrtLnN, PID: 2409589
-
Wilson SS, Wiens ME, Smith JG. Antiviral mechanisms of human defensins. J Mol Biol. 2013;425(24):4965–80.
-
(2013)
J Mol Biol
, vol.425
, Issue.24
, pp. 4965-4980
-
-
Wilson, S.S.1
Wiens, M.E.2
Smith, J.G.3
|