-
1
-
-
0033400311
-
Nutrient tasting and signaling mechanisms in the gut. III. Endocrine cell recognition of luminal nutrients
-
Buchan AM. Nutrient tasting and signaling mechanisms in the gut. III. Endocrine cell recognition of luminal nutrients. Am J Physiol 1999; 277:G1103-G1107.
-
(1999)
Am J Physiol
, vol.277
-
-
Buchan, A.M.1
-
2
-
-
1842528431
-
Luminal sensing in the gut: An overview
-
Dockray GJ. Luminal sensing in the gut: an overview. J Physiol Pharmacol 2003; 54 (Suppl 4):9-17.
-
(2003)
J Physiol Pharmacol
, vol.54
, Issue.SUPPL. 4
, pp. 9-17
-
-
Dockray, G.J.1
-
4
-
-
0032733324
-
Nutrient tasting and signaling mechanisms in the gut. II. The intestine as a sensory organ: Neural, endocrine, and immune responses
-
Furness JB, Kunze WA, Clerc N. Nutrient tasting and signaling mechanisms in the gut. II. The intestine as a sensory organ: neural, endocrine, and immune responses. Am J Physiol 1999; 277:G922-G928.
-
(1999)
Am J Physiol
, vol.277
-
-
Furness, J.B.1
Kunze, W.A.2
Clerc, N.3
-
5
-
-
0031722813
-
The new biology of gastrointestinal hormones
-
Rehfeld JF. The new biology of gastrointestinal hormones. Physiol Rev 1998; 78:1087-1108.
-
(1998)
Physiol Rev
, vol.78
, pp. 1087-1108
-
-
Rehfeld, J.F.1
-
6
-
-
0029794029
-
Gastric endocrine cells: Gene expression, processing, and targeting of active products
-
Dockray GJ, Varro A, Dimaline R. Gastric endocrine cells: gene expression, processing, and targeting of active products. Physiol Rev 1996; 76:767-798.
-
(1996)
Physiol Rev
, vol.76
, pp. 767-798
-
-
Dockray, G.J.1
Varro, A.2
Dimaline, R.3
-
7
-
-
13944270377
-
Gut endocrine secretions and their relevance to satiety
-
Dockray G. Gut endocrine secretions and their relevance to satiety. Curr Opin Pharmacol 2004; 4:557-560.
-
(2004)
Curr Opin Pharmacol
, vol.4
, pp. 557-560
-
-
Dockray, G.1
-
8
-
-
11144338712
-
Gastrointestinal hormones and food intake
-
Strader AD, Woods SC. Gastrointestinal hormones and food intake. Gastroenterology 2005; 128:175-191.
-
(2005)
Gastroenterology
, vol.128
, pp. 175-191
-
-
Strader, A.D.1
Woods, S.C.2
-
9
-
-
0035043906
-
Gastrin, CCK, signaling, and cancer
-
Rozengurt E, Walsh JH. Gastrin, CCK, signaling, and cancer. Annu Rev Physiol 2001; 63:49-76.
-
(2001)
Annu Rev Physiol
, vol.63
, pp. 49-76
-
-
Rozengurt, E.1
Walsh, J.H.2
-
10
-
-
0035758109
-
Peripheral signals conveying metabolic information to the brain: Short-term and long-term regulation of food intake and energy homeostasis
-
Havel PJ. Peripheral signals conveying metabolic information to the brain: short-term and long-term regulation of food intake and energy homeostasis. Exp Biol Med (Maywood) 2001; 226:963-977.
-
(2001)
Exp Biol Med (Maywood)
, vol.226
, pp. 963-977
-
-
Havel, P.J.1
-
11
-
-
0038116505
-
Chylomicron components activate duodenal vagal afferents via a cholecystokinin. A receptor-mediated pathway to inhibit gastric motor function in the rat
-
Glatzle J, Wang Y, Adelson DW, et al. Chylomicron components activate duodenal vagal afferents via a cholecystokinin. A receptor-mediated pathway to inhibit gastric motor function in the rat. J Physiol 2003; 550:657-664.
-
(2003)
J Physiol
, vol.550
, pp. 657-664
-
-
Glatzle, J.1
Wang, Y.2
Adelson, D.W.3
-
12
-
-
0021278421
-
The ileal brake: Inhibition of jejunal motility after ileal fat perfusion in man
-
Spiller RC, Trotman IF, Higgins BE, et al. The ileal brake: inhibition of jejunal motility after ileal fat perfusion in man. Gut 1984; 25:365-374.
-
(1984)
Gut
, vol.25
, pp. 365-374
-
-
Spiller, R.C.1
Trotman, I.F.2
Higgins, B.E.3
-
13
-
-
0041859261
-
Inhibition of food intake in obese subjects by peptide YY3-36
-
Batterham RL, Cohen MA, Ellis SM, et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 2003; 349:941-948.
-
(2003)
N Engl J Med
, vol.349
, pp. 941-948
-
-
Batterham, R.L.1
Cohen, M.A.2
Ellis, S.M.3
-
14
-
-
17844395786
-
Peripheral administration of PYY(3-36) produces conditioned taste aversion in mice
-
Halatchev IG, Cone RD. Peripheral administration of PYY(3-36) produces conditioned taste aversion in mice. Cell Metab 2005; 1:159-168.
-
(2005)
Cell Metab
, vol.1
, pp. 159-168
-
-
Halatchev, I.G.1
Cone, R.D.2
-
15
-
-
3142736319
-
-
Tschop M, Castaneda TR, Joost HG, et al. Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature 2004; 430:1; page following 165; discussion 2 page following 165.
-
Tschop M, Castaneda TR, Joost HG, et al. Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature 2004; 430:1; page following 165; discussion 2 page following 165.
-
-
-
-
16
-
-
21744433419
-
Biological actions of the incretins GIP and GLP-1 and therapeutic perspectives in patients with type 2 diabetes
-
Gautier JF, Fetita S, Sobngwi E, Salaun-Martin C. Biological actions of the incretins GIP and GLP-1 and therapeutic perspectives in patients with type 2 diabetes. Diabetes Metab 2005; 31:233-242.
-
(2005)
Diabetes Metab
, vol.31
, pp. 233-242
-
-
Gautier, J.F.1
Fetita, S.2
Sobngwi, E.3
Salaun-Martin, C.4
-
17
-
-
0032958126
-
Glucagonlike peptide-1 (GLP-1) participation in ileal brake induced by intraluminal peptones in rat
-
Giralt M, Vergara P. Glucagonlike peptide-1 (GLP-1) participation in ileal brake induced by intraluminal peptones in rat. Dig Dis Sci 1999; 44:322-329.
-
(1999)
Dig Dis Sci
, vol.44
, pp. 322-329
-
-
Giralt, M.1
Vergara, P.2
-
18
-
-
33846032275
-
Gastrointestinal regulation of food intake
-
Cummings DE, Overduin J. Gastrointestinal regulation of food intake. J Clin Invest 2007; 117:13-23.
-
(2007)
J Clin Invest
, vol.117
, pp. 13-23
-
-
Cummings, D.E.1
Overduin, J.2
-
19
-
-
0037372616
-
Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying
-
Raybould HE, Glatzle J, Robin C, et al. Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying. Am J Physiol Gastrointest Liver Physiol 2003; 284:G367-G372.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Raybould, H.E.1
Glatzle, J.2
Robin, C.3
-
20
-
-
0035855939
-
Receptors and transduction in taste
-
Lindemann B. Receptors and transduction in taste. Nature 2001; 413:219-225.
-
(2001)
Nature
, vol.413
, pp. 219-225
-
-
Lindemann, B.1
-
21
-
-
0034677655
-
T2Rs function as bitter taste receptors
-
Chandrashekar J, Mueller KL, Hoon MA, et al. T2Rs function as bitter taste receptors. Cell 2000; 100:703-711.
-
(2000)
Cell
, vol.100
, pp. 703-711
-
-
Chandrashekar, J.1
Mueller, K.L.2
Hoon, M.A.3
-
23
-
-
0034677653
-
A novel family of mammalian taste receptors
-
Adler E, Hoon MA, Mueller KL, et al. A novel family of mammalian taste receptors. Cell 2000; 100:693-702.
-
(2000)
Cell
, vol.100
, pp. 693-702
-
-
Adler, E.1
Hoon, M.A.2
Mueller, K.L.3
-
24
-
-
0037016771
-
Molecular mechanisms of bitter and sweet taste transduction
-
Margolskee RF. Molecular mechanisms of bitter and sweet taste transduction. J Biol Chem 2002; 277:1-4.
-
(2002)
J Biol Chem
, vol.277
, pp. 1-4
-
-
Margolskee, R.F.1
-
25
-
-
0242440813
-
Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli
-
Caicedo A, Pereira E, Margolskee RF, Roper SD. Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli. J Neurosci 2003; 23:9947-9952.
-
(2003)
J Neurosci
, vol.23
, pp. 9947-9952
-
-
Caicedo, A.1
Pereira, E.2
Margolskee, R.F.3
Roper, S.D.4
-
26
-
-
0029957779
-
Transduction of bitter and sweet taste by gustducin
-
Wong GT, Gannon KS, Margolskee RF. Transduction of bitter and sweet taste by gustducin. Nature 1996; 381:796-800.
-
(1996)
Nature
, vol.381
, pp. 796-800
-
-
Wong, G.T.1
Gannon, K.S.2
Margolskee, R.F.3
-
27
-
-
33751100128
-
Co-localization of the {alpha} subunit of gustducin with PYY and GLP-1 in L cells of human colon
-
Rozengurt N, Wu S, Chen MC, et al. Co-localization of the {alpha} subunit of gustducin with PYY and GLP-1 in L cells of human colon. Am J Physiol Gastrointest Liver Physiol 2006; 291:G792-G802.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.291
-
-
Rozengurt, N.1
Wu, S.2
Chen, M.C.3
-
28
-
-
25144464874
-
Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat
-
Wu SV, Chen MC, Rozengurt E. Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat. Physiol Genomics 2005; 22:139-149.
-
(2005)
Physiol Genomics
, vol.22
, pp. 139-149
-
-
Wu, S.V.1
Chen, M.C.2
Rozengurt, E.3
-
29
-
-
0037133261
-
Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells
-
Wu SV, Rozengurt N, Yang M, et al. Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells. Proc Natl Acad Sci U S A 2002; 99:2392-2397.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2392-2397
-
-
Wu, S.V.1
Rozengurt, N.2
Yang, M.3
-
30
-
-
14644415512
-
Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells
-
Dyer J, Salmon KS, Zibrik L, Shirazi-Beechey SP. Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells. Biochem Soc Trans 2005; 33:302-305.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 302-305
-
-
Dyer, J.1
Salmon, K.S.2
Zibrik, L.3
Shirazi-Beechey, S.P.4
-
31
-
-
34347236558
-
-
Mace OJ, Affleck J, Patel N, Kellett GL. Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2. J Physiol 2007; 582:379-392. This study supports the functionality of sweet taste receptors in the gut by showing the increase of glucose transporter in response to sweet taste ligands, which is likely due to the activation of sweet taste receptors expressed in the gut.
-
Mace OJ, Affleck J, Patel N, Kellett GL. Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2. J Physiol 2007; 582:379-392. This study supports the functionality of sweet taste receptors in the gut by showing the increase of glucose transporter in response to sweet taste ligands, which is likely due to the activation of sweet taste receptors expressed in the gut.
-
-
-
-
32
-
-
35448995622
-
-
Margolskee RF, Dyer J, Kokrashvili Z, et al. T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Proc Natl Acad Sci U S A 2007; 104:15075-15080. This study provides evidence that sweet taste receptor molecules act as luminal sensors for sugars and sweeteners supporting their participation in physiological responses that can affect carbohydrate absorption and regulation of insulin release.
-
Margolskee RF, Dyer J, Kokrashvili Z, et al. T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Proc Natl Acad Sci U S A 2007; 104:15075-15080. This study provides evidence that sweet taste receptor molecules act as luminal sensors for sugars and sweeteners supporting their participation in physiological responses that can affect carbohydrate absorption and regulation of insulin release.
-
-
-
-
33
-
-
33845865790
-
Taste-signaling proteins are coexpressed in solitary intestinal epithelial cells
-
Bezencon C, le Coutre J, Damak S. Taste-signaling proteins are coexpressed in solitary intestinal epithelial cells. Chem Senses 2007; 32:41-49.
-
(2007)
Chem Senses
, vol.32
, pp. 41-49
-
-
Bezencon, C.1
le Coutre, J.2
Damak, S.3
-
34
-
-
33847078811
-
Taste receptors in the gastrointestinal tract. IV. Functional implications of bitter taste receptors in gastrointestinal chemosensing
-
Sternini C. Taste receptors in the gastrointestinal tract. IV. Functional implications of bitter taste receptors in gastrointestinal chemosensing. Am J Physiol Gastrointest Liver Physiol 2007; 292:G457-G461.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
-
-
Sternini, C.1
-
35
-
-
0031713194
-
Identification of the taste cell G-protein, alpha-gustducin, in brush cells of the rat pancreatic duct system
-
Hofer D, Drenckhahn D. Identification of the taste cell G-protein, alpha-gustducin, in brush cells of the rat pancreatic duct system. Histochem Cell Biol 1998; 110:303-309.
-
(1998)
Histochem Cell Biol
, vol.110
, pp. 303-309
-
-
Hofer, D.1
Drenckhahn, D.2
-
36
-
-
0029908546
-
Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin
-
Hofer D, Puschel B, Drenckhahn D. Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin. Proc Natl Acad Sci U S A 1996;93:6631-6634.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 6631-6634
-
-
Hofer, D.1
Puschel, B.2
Drenckhahn, D.3
-
37
-
-
33745769295
-
Taste receptors in the gastrointestinal tract. I. Bitter taste receptors and {alpha}-gustducin in the mammalian gut
-
Rozengurt E. Taste receptors in the gastrointestinal tract. I. Bitter taste receptors and {alpha}-gustducin in the mammalian gut. Am J Physiol Gastrointest Liver Physiol 2006; 291:G171-G177.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.291
-
-
Rozengurt, E.1
-
38
-
-
35448986920
-
-
Jang HJ, Kokrashvili Z, Theodorakis MJ, et al. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci U S A 2007; 104:15069-15074. This study supports the functional significance of taste receptor signaling molecules in the gut by showing that enteroendocrine cells might act as sensors for lumen glucose with the same mechanisms as taste cells in the mouth.
-
Jang HJ, Kokrashvili Z, Theodorakis MJ, et al. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci U S A 2007; 104:15069-15074. This study supports the functional significance of taste receptor signaling molecules in the gut by showing that enteroendocrine cells might act as sensors for lumen glucose with the same mechanisms as taste cells in the mouth.
-
-
-
-
40
-
-
33749352662
-
-
2+]i and CCK release in response to bitter taste agonists.
-
2+]i and CCK release in response to bitter taste agonists.
-
-
-
|