CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

Nature

Volumn 495, Issue 7440, 2013, Pages 223-226

  Taruno, Akiyuki ^a   Vingtdeux, Valérie ^b   Ohmoto, Makoto ^c   Ma, Zhongming ^a   Dvoryanchikov, Gennady ^d   Li, Ang ^a,g   Adrien, Leslie ^b   Zhao, Haitian ^b   Leung, Sze ^e   Abernethy, Maria ^e   Koppel, Jeremy ^b   Davies, Peter ^b,f   Civan, Mortimer M ^a   Chaudhari, Nirupa ^d   Matsumoto, Ichiro ^c   Hellekant, Göran ^e   Tordoff, Michael G ^c   Marambaud, Philippe ^b   Foskett, J Kevin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c MONELL CHEMICAL SENSES CENTER   (United States)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^g UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM HOMEOSTASIS MODULATOR 1; ION CHANNEL; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL M5; UNCLASSIFIED DRUG;

CELL ORGANELLE; HOMEOSTASIS; ION EXCHANGE; NEUROLOGY; TASTE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BITTER TASTE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; HETEROLOGOUS EXPRESSION; ION CURRENT; MALE; MOUSE; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STIMULUS RESPONSE; SWEETNESS; TASTE; TASTE BUD; TASTE DISCRIMINATION; UMAMI TASTE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM CHANNELS; FEMALE; HELA CELLS; HUMANS; ION CHANNEL GATING; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; RECEPTORS, PURINERGIC; SINGLE-CELL ANALYSIS; SYNAPTIC TRANSMISSION; TASTE; TASTE BUDS;

MUS;

EID: 84874956365     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11906     Document Type: Article

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