Cholinergic chemosensory cells in the trachea regulate breathing

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 23, 2011, Pages 9478-9483

  Krasteva, Gabriela ^a   Canning, Brendan J ^a   Hartmann, Petra ^a   Veres, Tibor Z ^b   Papadakis, Tamara ^a   Mühlfeld, Christian ^a   Schliecker, Kirstin ^a   Tallini, Yvonne N ^c   Braun, Armin ^b   Hackstein, Holger ^d   Baal, Nelli ^d   Weihe, Eberhard ^e   Schütz, Burkhard ^e   Kotlikoff, Michael ^c   Ibanez Tallon, Ines ^f   Kummer, Wolfgang ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

^c FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^d Animal Health Diagnostic Center   (United States)

^e PHILIPPS UNIVERSITY MARBURG   (Germany)

^f MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Airway sensory innervation; Bitter tasting substances; Jugular nodose ganglion; Respiratory epithelium

Indexed keywords

ACETYLCHOLINE; CHOLINERGIC RECEPTOR; CYCLOHEXIMIDE; PHOSPHOLIPASE C BETA2;

ANIMAL CELL; ARTICLE; BREATHING; BREATHING RATE; BRUSH BORDER; CHOLINERGIC SYSTEM; CONTROLLED STUDY; EVOKED RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; TRACHEA;

ANIMALS; CHEMORECEPTOR CELLS; CHOLINE O-ACETYLTRANSFERASE; FEMALE; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HETEROTRIMERIC GTP-BINDING PROTEINS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICROFILAMENT PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROVILLI; PHOSPHOLIPASE C BETA; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC; RESPIRATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TASTE; TRACHEA; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

EID: 79959346115     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1019418108     Document Type: Article

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