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Volumn 22, Issue , 2005, Pages 139-149

Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat

Author keywords

Calcium flux; Gustducin; Neuroendocrine cells; Transducin

Indexed keywords

CALCIUM ION; CYCLOHEXIMIDE; DENATONIUM BENZOATE; G PROTEIN COUPLED RECEPTOR; PHENYLTHIOUREA;

EID: 25144464874     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00030.2005     Document Type: Article
Times cited : (111)

References (29)
  • 2
    • 0028126482 scopus 로고
    • PTC/PROP tasting: Anatomy, psychophysics, and sex effects
    • Bartoshuk LM, Duffy VB, and Miller IJ. PTC/PROP tasting: anatomy, psychophysics, and sex effects. Physiol Behav 56: 1165-1171, 1994.
    • (1994) Physiol Behav , vol.56 , pp. 1165-1171
    • Bartoshuk, L.M.1    Duffy, V.B.2    Miller, I.J.3
  • 4
    • 0035936911 scopus 로고    scopus 로고
    • Taste receptor cells that discriminate between bitter stimuli
    • Caicedo A and Roper SD. Taste receptor cells that discriminate between bitter stimuli. Science 291: 1557-1560, 2001.
    • (2001) Science , vol.291 , pp. 1557-1560
    • Caicedo, A.1    Roper, S.D.2
  • 7
  • 8
    • 0036988501 scopus 로고    scopus 로고
    • Identification and characterization of human taste receptor genes belonging to the TAS2R family
    • Conte C, Ebeling M, Marcuz A, Nef P, and Andres-Barquin PJ. Identification and characterization of human taste receptor genes belonging to the TAS2R family. Cytogenet Genome Res 98: 45-53, 2002.
    • (2002) Cytogenet Genome Res , vol.98 , pp. 45-53
    • Conte, C.1    Ebeling, M.2    Marcuz, A.3    Nef, P.4    Andres-Barquin, P.J.5
  • 9
    • 0042040501 scopus 로고    scopus 로고
    • Evolutionary relationships of the Tas2r receptor gene families in mouse and human
    • Conte C, Ebeling M, Marcuz A, Nef P, and Andres-Barquin PJ. Evolutionary relationships of the Tas2r receptor gene families in mouse and human. Physiol Genomics 14: 73-82, 2003.
    • (2003) Physiol Genomics , vol.14 , pp. 73-82
    • Conte, C.1    Ebeling, M.2    Marcuz, A.3    Nef, P.4    Andres-Barquin, P.J.5
  • 10
    • 0030915416 scopus 로고    scopus 로고
    • Neural responses to bitter compounds in rats
    • Dahl M, Erickson RP, and Simon SA. Neural responses to bitter compounds in rats. Brain Res 756: 22-34, 1997.
    • (1997) Brain Res , vol.756 , pp. 22-34
    • Dahl, M.1    Erickson, R.P.2    Simon, S.A.3
  • 11
    • 14544295509 scopus 로고    scopus 로고
    • Evolution of bitter taste receptors in humans and apes
    • Fischer A, Gilad Y, Man O, and Paabo S. Evolution of bitter taste receptors in humans and apes. Mol Biol Evol 22: 432-436, 2004.
    • (2004) Mol Biol Evol , vol.22 , pp. 432-436
    • Fischer, A.1    Gilad, Y.2    Man, O.3    Paabo, S.4
  • 12
    • 0032848420 scopus 로고    scopus 로고
    • Regulation of cholecystokinin-mediated amylase secretion by leptin in rat pancreatic acinar tumor cell line AR42J
    • Harris DM, Flannigan KL, Go VL, and Wu SV. Regulation of cholecystokinin-mediated amylase secretion by leptin in rat pancreatic acinar tumor cell line AR42J. Pancreas 19: 224-230, 1999.
    • (1999) Pancreas , vol.19 , pp. 224-230
    • Harris, D.M.1    Flannigan, K.L.2    Go, V.L.3    Wu, S.V.4
  • 13
    • 0031713194 scopus 로고    scopus 로고
    • Identification of the taste cell G-protein, alpha-gustducin, in brush cells of the rat pancreatic duct system
    • Hofer D and Drenckhahn D. Identification of the taste cell G-protein, alpha-gustducin, in brush cells of the rat pancreatic duct system. Histochem Cell Biol 110: 303-309, 1998.
    • (1998) Histochem Cell Biol , vol.110 , pp. 303-309
    • Hofer, D.1    Drenckhahn, D.2
  • 14
    • 0029908546 scopus 로고    scopus 로고
    • Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin
    • Hofer D, Puschel B, and Drenckhahn D. Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin. Proc Natl Acad Sci USA 93: 6631-6634, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6631-6634
    • Hofer, D.1    Puschel, B.2    Drenckhahn, D.3
  • 15
    • 0037458815 scopus 로고    scopus 로고
    • Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide
    • Kim UK, Jorgerason E, Coon H, Leppert M, Risch N, and Drayna D. Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science 299: I22I-I225, 2003.
    • (2003) Science , vol.299
    • Kim, U.K.1    Jorgerason, E.2    Coon, H.3    Leppert, M.4    Risch, N.5    Drayna, D.6
  • 16
    • 0034611738 scopus 로고    scopus 로고
    • A family of candidate taste receptors in human and mouse
    • Matsunami H, Montmayeur JP, and Buck LB. A family of candidate taste receptors in human and mouse. Nature 404: 601-604, 2000.
    • (2000) Nature , vol.404 , pp. 601-604
    • Matsunami, H.1    Montmayeur, J.P.2    Buck, L.B.3
  • 17
    • 3042825343 scopus 로고    scopus 로고
    • Taste sensitivities to PROP and PTC vary independently in mice
    • Nelson TM, Munger SD, and Boughter JD Jr. Taste sensitivities to PROP and PTC vary independently in mice. Chem Senses 28: 695-704, 2003.
    • (2003) Chem Senses , vol.28 , pp. 695-704
    • Nelson, T.M.1    Munger, S.D.2    Boughter Jr., J.D.3
  • 18
    • 0032744464 scopus 로고    scopus 로고
    • 2+ from intracellular stores: A novel mechanism for transduction of bitter stimuli
    • 2+ from intracellular stores: a novel mechanism for transduction of bitter stimuli. J Neurophysiol 82: 2657-2666, 1999.
    • (1999) J Neurophysiol , vol.82 , pp. 2657-2666
    • Ogura, T.1    Kinnamon, S.C.2
  • 19
    • 0030203863 scopus 로고    scopus 로고
    • TreeView: An application to display phylogenetic trees on personal computers
    • Page RB. TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 12: 357-358, 1996.
    • (1996) Comput Appl Biosci , vol.12 , pp. 357-358
    • Page, R.B.1
  • 20
    • 6944241419 scopus 로고    scopus 로고
    • Divergence of T2R chemosensory receptor families in humans, bonobos, and chimpanzees
    • Parry CM, Erkner A, and le Coutre J. Divergence of T2R chemosensory receptor families in humans, bonobos, and chimpanzees. Proc Natl Acad Sci USA 101: 14830-14834, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14830-14834
    • Parry, C.M.1    Erkner, A.2    Le Coutre, J.3
  • 21
    • 16644395918 scopus 로고    scopus 로고
    • Bitter taste study in a sardinian genetic isolate supports the association of phenylthiocarbamide sensitivity to the TAS2R38 bitter receptor gene
    • Prodi DA, Drayna D, Forabosco P, Palmas MA, Maestrale GB, Piras D, Pirastu M, and Angius A. Bitter taste study in a sardinian genetic isolate supports the association of phenylthiocarbamide sensitivity to the TAS2R38 bitter receptor gene. Chem Senses 29: 697-702, 2004.
    • (2004) Chem Senses , vol.29 , pp. 697-702
    • Prodi, D.A.1    Drayna, D.2    Forabosco, P.3    Palmas, M.A.4    Maestrale, G.B.5    Piras, D.6    Pirastu, M.7    Angius, A.8
  • 22
    • 8544242989 scopus 로고    scopus 로고
    • Identification of ligands for two human bitter T2R receptors
    • Pronin AN, Tang H, Connor J, and Keung W. Identification of ligands for two human bitter T2R receptors. Chem Senses 29: 583-593, 2004.
    • (2004) Chem Senses , vol.29 , pp. 583-593
    • Pronin, A.N.1    Tang, H.2    Connor, J.3    Keung, W.4
  • 23
    • 0028650312 scopus 로고
    • Rat pancreatic AR42J cells. Amphicrine cells as an in vitro model to study peptide hormone receptor regulation
    • Rosewicz S, Ahnert-Hilger G, Haller H, Riecken EO, and Wiedenmann B. Rat pancreatic AR42J cells. Amphicrine cells as an in vitro model to study peptide hormone receptor regulation. Ann NY Acad Sci 733: 407-415, 1994.
    • (1994) Ann NY Acad Sci , vol.733 , pp. 407-415
    • Rosewicz, S.1    Ahnert-Hilger, G.2    Haller, H.3    Riecken, E.O.4    Wiedenmann, B.5
  • 24
    • 0038708520 scopus 로고    scopus 로고
    • Adaptive diversification of bitter taste receptor genes in mammalian evolution
    • Shi P, Zhang J, Yang H, and Zhang YP. Adaptive diversification of bitter taste receptor genes in mammalian evolution. Mol Biol Evol 20: 805-814, 2003.
    • (2003) Mol Biol Evol , vol.20 , pp. 805-814
    • Shi, P.1    Zhang, J.2    Yang, H.3    Zhang, Y.P.4
  • 25
    • 0037315194 scopus 로고    scopus 로고
    • Stimulation of insulin secretion by denatonium, one of the most bitter-tasting substances known
    • Straub SG, Mulvaney-Musa J, Yajima H, Weiland GA, and Sharp GW. Stimulation of insulin secretion by denatonium, one of the most bitter-tasting substances known. Diabetes 52: 356-364, 2003.
    • (2003) Diabetes , vol.52 , pp. 356-364
    • Straub, S.G.1    Mulvaney-Musa, J.2    Yajima, H.3    Weiland, G.A.4    Sharp, G.W.5
  • 26
    • 0034795163 scopus 로고    scopus 로고
    • Identification of coding single-nucleotide polymorphisms in human taste receptor genes involving bitter tasting
    • Ueda T, Ugawa S, Ishida Y, Shibata Y, Murakami S, and Shimada S. Identification of coding single-nucleotide polymorphisms in human taste receptor genes involving bitter tasting. Biochem Biophys Res Commun 285: 147-151, 2001.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 147-151
    • Ueda, T.1    Ugawa, S.2    Ishida, Y.3    Shibata, Y.4    Murakami, S.5    Shimada, S.6
  • 27
    • 8444225000 scopus 로고    scopus 로고
    • Relaxation of selective constraint and loss of function in the evolution of human bitter taste receptor genes
    • Wang X, Thomas SD, and Zhang J. Relaxation of selective constraint and loss of function in the evolution of human bitter taste receptor genes. Hum Mol Genet 13: 2671-2678, 2004.
    • (2004) Hum Mol Genet , vol.13 , pp. 2671-2678
    • Wang, X.1    Thomas, S.D.2    Zhang, J.3
  • 28
    • 0028073320 scopus 로고
    • Genetics of bitter perception in mice
    • Whitney G and Harder DB. Genetics of bitter perception in mice. Physiol Behav 56: 1141-1147, 1994.
    • (1994) Physiol Behav , vol.56 , pp. 1141-1147
    • Whitney, G.1    Harder, D.B.2
  • 29
    • 0037133261 scopus 로고    scopus 로고
    • Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells
    • Wu SV, Rozengurt N, Yang M, Young SH, Sinnett-Smith J, and Rozengurt E. Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells. Proc Natl Acad Sci USA 99: 2392-2397, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2392-2397
    • Wu, S.V.1    Rozengurt, N.2    Yang, M.3    Young, S.H.4    Sinnett-Smith, J.5    Rozengurt, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.