-
1
-
-
18944395803
-
Nucleophosmin/B23, a nuclear PI(3, 4, 5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD
-
Ahn, J. Y., Liu, X., Cheng, D., Peng, J., Chan, P. K., Wade, P. A., et al. (2005). Nucleophosmin/B23, a nuclear PI(3, 4, 5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD. Mol. Cell 18, 435-445. doi: 10.1016/j.molcel.2005.04.010
-
(2005)
Mol. Cell
, vol.18
, pp. 435-445
-
-
Ahn, J.Y.1
Liu, X.2
Cheng, D.3
Peng, J.4
Chan, P.K.5
Wade, P.A.6
-
2
-
-
8144228424
-
PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus
-
Ahn, J. Y., Rong, R., Liu, X., and Ye, K. (2004). PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus. EMBO J. 23, 3995-4006. doi: 10.1038/sj.emboj.7600392
-
(2004)
EMBO J
, vol.23
, pp. 3995-4006
-
-
Ahn, J.Y.1
Rong, R.2
Liu, X.3
Ye, K.4
-
3
-
-
21444444598
-
Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair
-
Alt, J. R., Bouska, A., Fernandez, M. R., Cerny, R. L., Xiao, H., and Eischen, C. M. (2005). Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair. J. Biol. Chem. 280, 18771-18781. doi: 10.1074/jbc.M413387200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 18771-18781
-
-
Alt, J.R.1
Bouska, A.2
Fernandez, M.R.3
Cerny, R.L.4
Xiao, H.5
Eischen, C.M.6
-
4
-
-
0027533679
-
Oncogenic activity of the c-Myc protein requires dimerization with Max
-
Amati, B., Brooks, M. W., Levy, N., Littlewood, T. D., Evan, G. I., and Land, H. (1993). Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell 72, 233-245. doi: 10.1016/0092-8674(93)90663-B
-
(1993)
Cell
, vol.72
, pp. 233-245
-
-
Amati, B.1
Brooks, M.W.2
Levy, N.3
Littlewood, T.D.4
Evan, G.I.5
Land, H.6
-
5
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic, M., Alessi, D. R., Meier, R., Fernandez, A., Lamb, N. J., Frech, M., et al. (1997). Role of translocation in the activation and function of protein kinase B. J. Biol. Chem. 272, 31515-31524. doi: 10.1074/jbc.272.50.31515
-
(1997)
J. Biol. Chem
, vol.272
, pp. 31515-31524
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.J.5
Frech, M.6
-
6
-
-
15644362968
-
Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity
-
Arcaro, A., Volinia, S., Zvelebil, M. J., Stein, R., Watton, S. J., Layton, M. J., et al. (1998). Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity. J. Biol. Chem. 273, 33082-33090. doi: 10.1074/jbc.273.49.33082
-
(1998)
J. Biol. Chem
, vol.273
, pp. 33082-33090
-
-
Arcaro, A.1
Volinia, S.2
Zvelebil, M.J.3
Stein, R.4
Watton, S.J.5
Layton, M.J.6
-
7
-
-
77952077124
-
Subcellular localization of activated AKT in estrogen receptor-and progesterone receptor-expressing breast cancers: potential clinical implications
-
Badve, S., Collins, N. R., Bhat-Nakshatri, P., Turbin, D., Leung, S., Thorat, M., et al. (2010). Subcellular localization of activated AKT in estrogen receptor-and progesterone receptor-expressing breast cancers: potential clinical implications. Am. J. Pathol. 176, 2139-2149. doi: 10.2353/ajpath.2010.090477
-
(2010)
Am. J. Pathol
, vol.176
, pp. 2139-2149
-
-
Badve, S.1
Collins, N.R.2
Bhat-Nakshatri, P.3
Turbin, D.4
Leung, S.5
Thorat, M.6
-
8
-
-
0034653998
-
c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover
-
Bahram, F., N., von der Lehr, Cetinkaya, C., and Larsson, L. G. (2000). c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover. Blood 95, 2104-2110
-
(2000)
Blood
, vol.95
, pp. 2104-2110
-
-
Bahram, F.N.1
von der Lehr Cetinkaya, C.2
Larsson, L.G.3
-
9
-
-
68749119758
-
Epidermal growth factor stimulates translocation of the class II phosphoinositide 3-kinase PI3K-C2beta to the nucleus
-
Banfic, H., Visnjic, D., Mise, N., Balakrishnan, S., Deplano, S., Korchev, Y. E., et al. (2009). Epidermal growth factor stimulates translocation of the class II phosphoinositide 3-kinase PI3K-C2beta to the nucleus. Biochem. J. 422, 53-60. doi: 10.1042/BJ20090654
-
(2009)
Biochem. J
, vol.422
, pp. 53-60
-
-
Banfic, H.1
Visnjic, D.2
Mise, N.3
Balakrishnan, S.4
Deplano, S.5
Korchev, Y.E.6
-
10
-
-
84880710673
-
Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress
-
Bassi, C., Ho, J., Srikumar, T., Dowling, R. J., Gorrini, C., Miller, S. J., et al. (2013). Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress. Science 341, 395-399. doi: 10.1126/science.1236188
-
(2013)
Science
, vol.341
, pp. 395-399
-
-
Bassi, C.1
Ho, J.2
Srikumar, T.3
Dowling, R.J.4
Gorrini, C.5
Miller, S.J.6
-
11
-
-
84863420854
-
Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells
-
Bechard, M., Trost, R., Singh, A. M., and Dalton, S. (2012). Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells. Mol. Cell. Biol. 32, 288-296. doi: 10.1128/MCB.05372-11
-
(2012)
Mol. Cell. Biol
, vol.32
, pp. 288-296
-
-
Bechard, M.1
Trost, R.2
Singh, A.M.3
Dalton, S.4
-
12
-
-
46649120323
-
The ins and outs of syntenin, a multifunctional intracellular adaptor protein
-
Beekman, J. M., and Coffer, P. J. (2008). The ins and outs of syntenin, a multifunctional intracellular adaptor protein. J. Cell Sci. 121, 1349-1355. doi: 10.1242/jcs.026401
-
(2008)
J. Cell Sci
, vol.121
, pp. 1349-1355
-
-
Beekman, J.M.1
Coffer, P.J.2
-
13
-
-
0036185944
-
Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase
-
Bi, L., Okabe, I., Bernard, D. J., and Nussbaum, R. L. (2002). Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase. Mamm. Genome 13, 169-172. doi: 10.1007/BF02684023
-
(2002)
Mamm. Genome
, vol.13
, pp. 169-172
-
-
Bi, L.1
Okabe, I.2
Bernard, D.J.3
Nussbaum, R.L.4
-
14
-
-
0033574429
-
Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase
-
Bi, L., Okabe, I., Bernard, D. J., Wynshaw-Boris, A., and Nussbaum, R. L. (1999). Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase. J. Biol. Chem. 274, 10963-10968. doi: 10.1074/jbc.274.16.10963
-
(1999)
J. Biol. Chem
, vol.274
, pp. 10963-10968
-
-
Bi, L.1
Okabe, I.2
Bernard, D.J.3
Wynshaw-Boris, A.4
Nussbaum, R.L.5
-
15
-
-
49349108776
-
Structure and function of ribosomal RNA gene chromatin
-
Birch, J. L., and Zomerdijk, J. C. (2008). Structure and function of ribosomal RNA gene chromatin. Biochem. Soc. Trans. 36, 619-624. doi: 10.1042/BST0360619
-
(2008)
Biochem. Soc. Trans
, vol.36
, pp. 619-624
-
-
Birch, J.L.1
Zomerdijk, J.C.2
-
16
-
-
84908065769
-
The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1
-
Blind, R. D., Sablin, E. P., Kuchenbecker, K. M., Chiu, H.-J., Deacon, A. M., Das, D., et al. (2014). The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1. Proc. Natl. Acad. Sci. U.S.A. 111, 15054-15059. doi: 10.1073/pnas.1416740111
-
(2014)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. 15054-15059
-
-
Blind, R.D.1
Sablin, E.P.2
Kuchenbecker, K.M.3
Chiu, H.-J.4
Deacon, A.M.5
Das, D.6
-
17
-
-
84862884630
-
Direct modification and activation of a nuclear receptor-PIP2 complex by the inositol lipid kinase IPMK
-
Blind, R. D., Suzawa, M., and Ingraham, H. A. (2012). Direct modification and activation of a nuclear receptor-PIP2 complex by the inositol lipid kinase IPMK. Sci. Signal. 5:ra44. doi: 10.1126/scisignal.2003111
-
(2012)
Sci. Signal
, vol.5
, pp. 44
-
-
Blind, R.D.1
Suzawa, M.2
Ingraham, H.A.3
-
18
-
-
45549104364
-
p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK
-
Boehme, K. A., Kulikov, R., and Blattner, C. (2008). p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK. Proc. Natl. Acad. Sci. U.S.A. 105, 7785-7790. doi: 10.1073/pnas.0703423105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 7785-7790
-
-
Boehme, K.A.1
Kulikov, R.2
Blattner, C.3
-
19
-
-
0024966024
-
Major nucleolar proteins shuttle between nucleus and cytoplasm
-
Borer, R. A., Lehner, C. F., Eppenberger, H. M., and Nigg, E. A. (1989). Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell 56, 379-390. doi: 10.1016/0092-8674(89)90241-9
-
(1989)
Cell
, vol.56
, pp. 379-390
-
-
Borer, R.A.1
Lehner, C.F.2
Eppenberger, H.M.3
Nigg, E.A.4
-
20
-
-
0031771547
-
Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors
-
Boronenkov, I. V., Loijens, J. C., Umeda, M., and Anderson, R. A. (1998). Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors. Mol. Biol. Cell 9, 3547-3560. doi: 10.1091/mbc.9.12.3547
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 3547-3560
-
-
Boronenkov, I.V.1
Loijens, J.C.2
Umeda, M.3
Anderson, R.A.4
-
21
-
-
3543028648
-
Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins
-
Bouchard, C., Marquardt, J., Bras, A., Medema, R. H., and Eilers, M. (2004). Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. EMBO J. 23, 2830-2840. doi: 10.1038/sj.emboj.7600279
-
(2004)
EMBO J
, vol.23
, pp. 2830-2840
-
-
Bouchard, C.1
Marquardt, J.2
Bras, A.3
Medema, R.H.4
Eilers, M.5
-
22
-
-
84864751451
-
Phosphatidylinositol 3, 5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1
-
Bridges, D., Ma, J.-T., Park, S., Inoki, K., Weisman, L. S., and Saltiel, A. R. (2012). Phosphatidylinositol 3, 5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1. Mol. Biol. Cell 23, 2955-2962. doi: 10.1091/mbc.E11-12-1034
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 2955-2962
-
-
Bridges, D.1
Ma, J.-T.2
Park, S.3
Inoki, K.4
Weisman, L.S.5
Saltiel, A.R.6
-
23
-
-
33947203621
-
PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms
-
Brognard, J., Sierecki, E., Gao, T., and Newton, A. C. (2007). PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms. Mol. Cell 25, 917-931. doi: 10.1016/j.molcel.2007.02.017
-
(2007)
Mol. Cell
, vol.25
, pp. 917-931
-
-
Brognard, J.1
Sierecki, E.2
Gao, T.3
Newton, A.C.4
-
24
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., et al. (1999). Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96, 857-868. doi: 10.1016/S0092-8674(00)80595-4
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
-
25
-
-
0347160176
-
p21CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase delta at the G1/S phase transition
-
Cazzalini, O., Perucca, P., Riva, F., Stivala, L. A., Bianchi, L., Vannini, V., et al. (2003). p21CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase delta at the G1/S phase transition. Cell Cycle 2, 596-603. doi: 10.4161/cc.2.6.502
-
(2003)
Cell Cycle
, vol.2
, pp. 596-603
-
-
Cazzalini, O.1
Perucca, P.2
Riva, F.3
Stivala, L.A.4
Bianchi, L.5
Vannini, V.6
-
26
-
-
80052282364
-
AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer
-
Chan, J. C., Hannan, K. M., Riddell, K., Ng, P. Y., Peck, A., Lee, R. S., et al. (2011). AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer. Sci. Signal. 4:ra56. doi: 10.1126/scisignal.2001754
-
(2011)
Sci. Signal
, vol.4
, pp. 56
-
-
Chan, J.C.1
Hannan, K.M.2
Riddell, K.3
Ng, P.Y.4
Peck, A.5
Lee, R.S.6
-
27
-
-
4644354099
-
SUMO modification of repression domains modulates function of nuclear receptor 5A1 (steroidogenic factor-1)
-
Chen, W.-Y., Lee, W.-C., Hsu, N.-C., Huang, F., and Chung, B.-C. (2004). SUMO modification of repression domains modulates function of nuclear receptor 5A1 (steroidogenic factor-1). J. Biol. Chem. 279, 38730-38735. doi: 10.1074/jbc.M405006200
-
(2004)
J. Biol. Chem
, vol.279
, pp. 38730-38735
-
-
Chen, W.-Y.1
Lee, W.-C.2
Hsu, N.-C.3
Huang, F.4
Chung, B.-C.5
-
28
-
-
84903464777
-
Cdh1, a substrate-recruiting component of anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, specifically interacts with phosphatase and tensin homolog (PTEN) and promotes its removal from chromatin
-
Choi, B. H., Pagano, M., Huang, C., and Dai, W. (2014). Cdh1, a substrate-recruiting component of anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, specifically interacts with phosphatase and tensin homolog (PTEN) and promotes its removal from chromatin. J. Biol. Chem. 289, 17951-17959. doi: 10.1074/jbc.M114.559005
-
(2014)
J. Biol. Chem
, vol.289
, pp. 17951-17959
-
-
Choi, B.H.1
Pagano, M.2
Huang, C.3
Dai, W.4
-
29
-
-
24944568790
-
Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis
-
Chung, J. H., and Eng, C. (2005). Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis. Cancer Res. 65, 8096-8100. doi: 10.1158/0008-5472.CAN-05-1888
-
(2005)
Cancer Res
, vol.65
, pp. 8096-8100
-
-
Chung, J.H.1
Eng, C.2
-
30
-
-
55649084906
-
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development
-
Ciraolo, E., Iezzi, M., Marone, R., Marengo, S., Curcio, C., Costa, C., et al. (2008). Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development. Sci. Signal. 1:ra3. doi: 10.1126/scisignal.1161577
-
(2008)
Sci. Signal
, vol.1
, pp. 3
-
-
Ciraolo, E.1
Iezzi, M.2
Marone, R.3
Marengo, S.4
Curcio, C.5
Costa, C.6
-
31
-
-
0034654363
-
Nuclear targeting of the beta isoform of type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its alpha-helix 7
-
Ciruela, A., Hinchliffe, K. A., Divecha, N., and Irvine, R. F. (2000). Nuclear targeting of the beta isoform of type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its alpha-helix 7. Biochem. J. 346(Pt 3), 587-591. doi: 10.1042/0264-6021:3460587
-
(2000)
Biochem. J
, vol.346
, pp. 587-591
-
-
Ciruela, A.1
Hinchliffe, K.A.2
Divecha, N.3
Irvine, R.F.4
-
32
-
-
0023657043
-
Synthesis of polyphosphoinositides in nuclei of Friend cells Evidence for polyphosphoinositide metabolism inside the nucleus which changes with cell differentiation
-
Cocco, L., Gilmour, R. S., Ognibene, A., Letcher, A. J., Manzoli, F. A., and Irvine, R. F. (1987). Synthesis of polyphosphoinositides in nuclei of Friend cells. Evidence for polyphosphoinositide metabolism inside the nucleus which changes with cell differentiation. Biochem. J. 248, 765-770
-
(1987)
Biochem. J
, vol.248
, pp. 765-770
-
-
Cocco, L.1
Gilmour, R.S.2
Ognibene, A.3
Letcher, A.J.4
Manzoli, F.A.5
Irvine, R.F.6
-
33
-
-
0033861775
-
Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis
-
Conzen, S. D., Gottlob, K., Kandel, E. S., Khanduri, P., Wagner, A. J., O'Leary, M., et al. (2000). Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis. Mol. Cell. Biol. 20, 6008-6018. doi: 10.1128/MCB.20.16.6008-6018.2000
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 6008-6018
-
-
Conzen, S.D.1
Gottlob, K.2
Kandel, E.S.3
Khanduri, P.4
Wagner, A.J.5
O'Leary, M.6
-
34
-
-
84964204680
-
Measurement of PIP3 levels reveals an unexpected role for p110beta in early adaptive responses to p110alpha-specific inhibitors in luminal breast cancer
-
Costa, C., Ebi, H., Martini, M., Beausoleil, S. A., Faber, A. C., Jakubik, C. T., et al. (2015). Measurement of PIP3 levels reveals an unexpected role for p110beta in early adaptive responses to p110alpha-specific inhibitors in luminal breast cancer. Cancer Cell 27, 97-108. doi: 10.1016/j.ccell.2014.11.007
-
(2015)
Cancer Cell
, vol.27
, pp. 97-108
-
-
Costa, C.1
Ebi, H.2
Martini, M.3
Beausoleil, S.A.4
Faber, A.C.5
Jakubik, C.T.6
-
35
-
-
34547151021
-
Inhibition of c-Myc activity by ribosomal protein L11
-
Dai, M.-S., Arnold, H., Sun, X.-X., Sears, R., and Lu, H. (2007). Inhibition of c-Myc activity by ribosomal protein L11. EMBO J. 26, 3332-3345. doi: 10.1038/sj.emboj.7601776
-
(2007)
EMBO J
, vol.26
, pp. 3332-3345
-
-
Dai, M.-S.1
Arnold, H.2
Sun, X.-X.3
Sears, R.4
Lu, H.5
-
36
-
-
84859171807
-
MYC on the path to cancer
-
Dang, C. V. (2012). MYC on the path to cancer. Cell 149, 22-35. doi: 10.1016/j.cell.2012.03.003
-
(2012)
Cell
, vol.149
, pp. 22-35
-
-
Dang, C.V.1
-
37
-
-
0141866729
-
SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles
-
Déléris, P., Bacqueville, D., Gayral, S., Carrez, L., Salles, J.-P., Perret, B., et al. (2003). SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles. J. Biol. Chem. 278, 38884-38891. doi: 10.1074/jbc.M300816200
-
(2003)
J. Biol. Chem
, vol.278
, pp. 38884-38891
-
-
Déléris, P.1
Bacqueville, D.2
Gayral, S.3
Carrez, L.4
Salles, J.-P.5
Perret, B.6
-
38
-
-
42249098543
-
Oncogenic signaling of class I PI3K isoforms
-
Denley, A., Kang, S., Karst, U., and Vogt, P. K. (2008). Oncogenic signaling of class I PI3K isoforms. Oncogene 27, 2561-2574. doi: 10.1038/sj.onc.1210918
-
(2008)
Oncogene
, vol.27
, pp. 2561-2574
-
-
Denley, A.1
Kang, S.2
Karst, U.3
Vogt, P.K.4
-
39
-
-
0035930577
-
Phosphatidylinositol 3-kinase c2alpha contains a nuclear localization sequence and associates with nuclear speckles
-
Didichenko, S. A., and Thelen, M. (2001). Phosphatidylinositol 3-kinase c2alpha contains a nuclear localization sequence and associates with nuclear speckles. J. Biol. Chem. 276, 48135-48142. doi: 10.1074/jbc.M104610200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 48135-48142
-
-
Didichenko, S.A.1
Thelen, M.2
-
40
-
-
0026040577
-
The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus
-
Divecha, N., BanfiC, H., and Irvine, R. F. (1991). The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus. EMBO J. 10, 3207-3214
-
(1991)
EMBO J
, vol.10
, pp. 3207-3214
-
-
Divecha, N.1
Banfi, C.H.2
Irvine, R.F.3
-
41
-
-
70449700091
-
Controlling subcellular localization to alter function: sending oncogenic Bcr-Abl to the nucleus causes apoptosis
-
Dixon, A. S., Kakar, M., Schneider, K. M., Constance, J. E., Paullin, B. C., and Lim, C. S. (2009). Controlling subcellular localization to alter function: sending oncogenic Bcr-Abl to the nucleus causes apoptosis. J. Control. Release 140, 245-249. doi: 10.1016/j.jconrel.2009.06.026
-
(2009)
J. Control. Release
, vol.140
, pp. 245-249
-
-
Dixon, A.S.1
Kakar, M.2
Schneider, K.M.3
Constance, J.E.4
Paullin, B.C.5
Lim, C.S.6
-
42
-
-
78349244834
-
The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy
-
Dou, Z., Chattopadhyay, M., Pan, J.-A., Guerriero, J. L., Jiang, Y.-P., Ballou, L. M., et al. (2010). The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy. J. Cell Biol. 191, 827-843. doi: 10.1083/jcb.201006056
-
(2010)
J. Cell Biol
, vol.191
, pp. 827-843
-
-
Dou, Z.1
Chattopadhyay, M.2
Pan, J.-A.3
Guerriero, J.L.4
Jiang, Y.-P.5
Ballou, L.M.6
-
43
-
-
3042647602
-
Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase
-
Drakas, R., Tu, X., and Baserga, R. (2004). Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. U.S.A. 101, 9272-9276. doi: 10.1073/pnas.0403328101
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 9272-9276
-
-
Drakas, R.1
Tu, X.2
Baserga, R.3
-
44
-
-
54349087788
-
Myc's broad reach
-
Eilers, M., and Eisenman, R. N. (2008). Myc's broad reach. Genes Dev. 22, 2755-2766. doi: 10.1101/gad.1712408
-
(2008)
Genes Dev
, vol.22
, pp. 2755-2766
-
-
Eilers, M.1
Eisenman, R.N.2
-
45
-
-
80054028201
-
Evidence of SHIP2 Ser132 phosphorylation, its nuclear localization and stability
-
Elong Edimo, W., Derua, R., Janssens, V., Nakamura, T., Vanderwinden, J. M., Waelkens, E., et al. (2011). Evidence of SHIP2 Ser132 phosphorylation, its nuclear localization and stability. Biochem. J. 439, 391-401. doi: 10.1042/BJ20110173
-
(2011)
Biochem. J
, vol.439
, pp. 391-401
-
-
Elong Edimo, W.1
Derua, R.2
Janssens, V.3
Nakamura, T.4
Vanderwinden, J.M.5
Waelkens, E.6
-
46
-
-
84874002628
-
SHIP2 signalling at the plasma membrane, in the nucleus and at focal contacts
-
Elong Edimo, W., Vanderwinden, J. M., and Erneux, C. (2013). SHIP2 signalling at the plasma membrane, in the nucleus and at focal contacts. Adv. Biol. Regul. 53, 28-37. doi: 10.1016/j.jbior.2012.09.003
-
(2013)
Adv. Biol. Regul
, vol.53
, pp. 28-37
-
-
Elong Edimo, W.1
Vanderwinden, J.M.2
Erneux, C.3
-
47
-
-
77954903710
-
Activity of any class IA PI3K isoform can sustain cell proliferation and survival
-
Foukas, L. C., Berenjeno, I. M., Gray, A., Khwaja, A., and Vanhaesebroeck, B. (2010). Activity of any class IA PI3K isoform can sustain cell proliferation and survival. Proc. Natl. Acad. Sci. U.S.A. 107, 11381-11386. doi: 10.1073/pnas.0906461107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 11381-11386
-
-
Foukas, L.C.1
Berenjeno, I.M.2
Gray, A.3
Khwaja, A.4
Vanhaesebroeck, B.5
-
48
-
-
33744990592
-
Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation
-
Foukas, L. C., Claret, M., Pearce, W., Okkenhaug, K., Meek, S., Peskett, E., et al. (2006). Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature 441, 366-370. doi: 10.1038/nature04694
-
(2006)
Nature
, vol.441
, pp. 366-370
-
-
Foukas, L.C.1
Claret, M.2
Pearce, W.3
Okkenhaug, K.4
Meek, S.5
Peskett, E.6
-
49
-
-
0037113982
-
The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP
-
Franca-Koh, J., Yeo, M., Fraser, E., Young, N., and Dale, T. C. (2002). The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP. J. Biol. Chem. 277, 43844-43848. doi: 10.1074/jbc.M207265200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 43844-43848
-
-
Franca-Koh, J.1
Yeo, M.2
Fraser, E.3
Young, N.4
Dale, T.C.5
-
50
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate
-
Franke, T. F., Kaplan, D. R., Cantley, L. C., and Toker, A. (1997). Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate. Science 275, 665-668. doi: 10.1126/science.275.5300.665
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
Toker, A.4
-
51
-
-
84893249799
-
PI3K and cancer: lessons, challenges and opportunities
-
Fruman, D. A., and Rommel, C. (2014). PI3K and cancer: lessons, challenges and opportunities. Nat. Rev. Drug Discov. 13, 140-156. doi: 10.1038/nrd4204
-
(2014)
Nat. Rev. Drug Discov
, vol.13
, pp. 140-156
-
-
Fruman, D.A.1
Rommel, C.2
-
52
-
-
39449099339
-
Role of poly (A) tail as an identity element for mRNA nuclear export
-
Fuke, H., and Ohno, M. (2008). Role of poly (A) tail as an identity element for mRNA nuclear export. Nucleic Acids Res. 36, 1037-1049. doi: 10.1093/nar/gkm1120
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1037-1049
-
-
Fuke, H.1
Ohno, M.2
-
53
-
-
15944406764
-
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
-
Gao, T., Furnari, F., and Newton, A. C. (2005). PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Mol. Cell 18, 13-24. doi: 10.1016/j.molcel.2005.03.008
-
(2005)
Mol. Cell
, vol.18
, pp. 13-24
-
-
Gao, T.1
Furnari, F.2
Newton, A.C.3
-
54
-
-
84872855144
-
Involvement of Akt isoforms in chemoresistance of endometrial carcinoma cells
-
Girouard, J., Lafleur, M. J., Parent, S., Leblanc, V., and Asselin, E. (2013). Involvement of Akt isoforms in chemoresistance of endometrial carcinoma cells. Gynecol. Oncol. 128, 335-343. doi: 10.1016/j.ygyno.2012.11.016
-
(2013)
Gynecol. Oncol
, vol.128
, pp. 335-343
-
-
Girouard, J.1
Lafleur, M.J.2
Parent, S.3
Leblanc, V.4
Asselin, E.5
-
55
-
-
0003288676
-
Beitrag zur histologie und aetiologie der carcinoma
-
Giuseppe, P. (1896). Beitrag zur histologie und aetiologie der carcinoma. Beitr. Pathol. Anat. Allgem. Pathol. 142, 1-193
-
(1896)
Beitr. Pathol. Anat. Allgem. Pathol
, vol.142
, pp. 1-193
-
-
Giuseppe, P.1
-
56
-
-
0347721764
-
Direct activation of RNA polymerase III transcription by c-Myc
-
Gomez-Roman, N., Grandori, C., Eisenman, R. N., and White, R. J. (2003). Direct activation of RNA polymerase III transcription by c-Myc. Nature 421, 290-294. doi: 10.1038/nature01327
-
(2003)
Nature
, vol.421
, pp. 290-294
-
-
Gomez-Roman, N.1
Grandori, C.2
Eisenman, R.N.3
White, R.J.4
-
57
-
-
18544371820
-
90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors
-
Grandi, P., Rybin, V., Bassler, J., Petfalski, E., Strauss, D., Marzioch, M., et al. (2002). 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol. Cell 10, 105-115. doi: 10.1016/S1097-2765(02)00579-8
-
(2002)
Mol. Cell
, vol.10
, pp. 105-115
-
-
Grandi, P.1
Rybin, V.2
Bassler, J.3
Petfalski, E.4
Strauss, D.5
Marzioch, M.6
-
58
-
-
14744284578
-
c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
-
Grandori, C., Gomez-Roman, N., Felton-Edkins, Z. A., Ngouenet, C., Galloway, D. A., Eisenman, R. N., et al. (2005). c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat. Cell Biol. 7, 311-318. doi: 10.1038/ncb1224
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 311-318
-
-
Grandori, C.1
Gomez-Roman, N.2
Felton-Edkins, Z.A.3
Ngouenet, C.4
Galloway, D.A.5
Eisenman, R.N.6
-
59
-
-
0347695988
-
Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization
-
Gregory, M. A., Qi, Y., and Hann, S. R. (2003). Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization. J. Biol. Chem. 278, 51606-51612. doi: 10.1074/jbc.M310722200
-
(2003)
J. Biol. Chem
, vol.278
, pp. 51606-51612
-
-
Gregory, M.A.1
Qi, Y.2
Hann, S.R.3
-
60
-
-
0242637318
-
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF
-
Hannan, K. M., Brandenburger, Y., Jenkins, A., Sharkey, K., Cavanaugh, A., Rothblum, L., et al. (2003). mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF. Mol. Cell. Biol. 23, 8862-8877. doi: 10.1128/MCB.23.23.8862-8877.2003
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 8862-8877
-
-
Hannan, K.M.1
Brandenburger, Y.2
Jenkins, A.3
Sharkey, K.4
Cavanaugh, A.5
Rothblum, L.6
-
61
-
-
0015422530
-
Location of ribosomal DNA in the human chromosome complement
-
Henderson, A. S., Warburton, D., and Atwood, K. C. (1972). Location of ribosomal DNA in the human chromosome complement. Proc. Natl. Acad. Sci. U.S.A. 69, 3394-3398. doi: 10.1073/pnas.69.11.3394
-
(1972)
Proc. Natl. Acad. Sci. U.S.A
, vol.69
, pp. 3394-3398
-
-
Henderson, A.S.1
Warburton, D.2
Atwood, K.C.3
-
62
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijmakers, J. H. (2001). Genome maintenance mechanisms for preventing cancer. Nature 411, 366-374. doi: 10.1038/35077232
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.1
-
63
-
-
84859366546
-
mTOR signaling regulates the processing of pre-rRNA in human cells
-
Iadevaia, V., Zhang, Z., Jan, E., and Proud, C. G. (2012). mTOR signaling regulates the processing of pre-rRNA in human cells. Nucleic Acids Res. 40, 2527-2539. doi: 10.1093/nar/gkr1040
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 2527-2539
-
-
Iadevaia, V.1
Zhang, Z.2
Jan, E.3
Proud, C.G.4
-
64
-
-
70349101615
-
Overexpression and activation of Akt2 protein in oral squamous cell carcinoma
-
Iamaroon, A., and Krisanaprakornkit, S. (2009). Overexpression and activation of Akt2 protein in oral squamous cell carcinoma. Oral Oncol. 45, e175-e179. doi: 10.1016/j.oraloncology.2009.06.003
-
(2009)
Oral Oncol
, vol.45
, pp. e175-e179
-
-
Iamaroon, A.1
Krisanaprakornkit, S.2
-
65
-
-
33749033347
-
The replication clamp-loading machine at work in the three domains of life
-
Indiani, C., and O'Donnell, M. (2006). The replication clamp-loading machine at work in the three domains of life. Nat. Rev. Mol. Cell Biol. 7, 751-761. doi: 10.1038/nrm2022
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 751-761
-
-
Indiani, C.1
O'Donnell, M.2
-
66
-
-
0345276485
-
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
-
Itahana, K., Bhat, K. P., Jin, A., Itahana, Y., Hawke, D., Kobayashi, R., et al. (2003). Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. Mol. Cell 12, 1151-1164. doi: 10.1016/S1097-2765(03)00431-3
-
(2003)
Mol. Cell
, vol.12
, pp. 1151-1164
-
-
Itahana, K.1
Bhat, K.P.2
Jin, A.3
Itahana, Y.4
Hawke, D.5
Kobayashi, R.6
-
67
-
-
1542305503
-
Phosphatidylinositol 3-kinase and mTOR signaling pathways regulate RNA polymerase I transcription in response to IGF-1 and nutrients
-
James, M. J., and Zomerdijk, J. C. (2004). Phosphatidylinositol 3-kinase and mTOR signaling pathways regulate RNA polymerase I transcription in response to IGF-1 and nutrients. J. Biol. Chem. 279, 8911-8918. doi: 10.1074/jbc.M307735200
-
(2004)
J. Biol. Chem
, vol.279
, pp. 8911-8918
-
-
James, M.J.1
Zomerdijk, J.C.2
-
68
-
-
49649087385
-
Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis
-
Jia, S., Liu, Z., Zhang, S., Liu, P., Zhang, L., Lee, S. H., et al. (2008). Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis. Nature 454, 776-779. doi: 10.1038/nature07091
-
(2008)
Nature
, vol.454
, pp. 776-779
-
-
Jia, S.1
Liu, Z.2
Zhang, S.3
Liu, P.4
Zhang, L.5
Lee, S.H.6
-
69
-
-
84898726041
-
Roles for PI(3, 5)P2 in nutrient sensing through TORC1
-
Jin, N., Mao, K., Jin, Y., Tevzadze, G., Kauffman, E. J., Park, S., et al. (2014). Roles for PI(3, 5)P2 in nutrient sensing through TORC1. Mol. Biol. Cell 25, 1171-1185. doi: 10.1091/mbc.E14-01-0021
-
(2014)
Mol. Biol. Cell
, vol.25
, pp. 1171-1185
-
-
Jin, N.1
Mao, K.2
Jin, Y.3
Tevzadze, G.4
Kauffman, E.J.5
Park, S.6
-
70
-
-
84868623830
-
Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis
-
Kikani, C. K., Verona, E. V., Ryu, J., Shen, Y., Ye, Q., Zheng, L., et al. (2012). Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis. Sci. Signal. 5:ra80. doi: 10.1126/scisignal.2003065
-
(2012)
Sci. Signal
, vol.5
, pp. 80
-
-
Kikani, C.K.1
Verona, E.V.2
Ryu, J.3
Shen, Y.4
Ye, Q.5
Zheng, L.6
-
71
-
-
84897406530
-
Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability
-
Kim, T.-H., Leslie, P., and Zhang, Y. (2014). Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability. Oncotarget 5, 860-871
-
(2014)
Oncotarget
, vol.5
, pp. 860-871
-
-
Kim, T.-H.1
Leslie, P.2
Zhang, Y.3
-
72
-
-
73449142838
-
Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH
-
Kirkegaard, T., Witton, C. J., Edwards, J., Nielsen, K. V., Jensen, L. B., Campbell, F. M., et al. (2010). Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH. Histopathology 56, 203-211. doi: 10.1111/j.1365-2559.2009.03467.x
-
(2010)
Histopathology
, vol.56
, pp. 203-211
-
-
Kirkegaard, T.1
Witton, C.J.2
Edwards, J.3
Nielsen, K.V.4
Jensen, L.B.5
Campbell, F.M.6
-
73
-
-
84875812144
-
Genetically engineered mouse models of PI3K signaling in breast cancer
-
Klarenbeek, S., van Miltenburg, M. H., and Jonkers, J. (2013). Genetically engineered mouse models of PI3K signaling in breast cancer. Mol. Oncol. 7, 146-164. doi: 10.1016/j.molonc.2013.02.003
-
(2013)
Mol. Oncol
, vol.7
, pp. 146-164
-
-
Klarenbeek, S.1
van Miltenburg, M.H.2
Jonkers, J.3
-
74
-
-
84875261248
-
TFIIB-related factors in RNA polymerase I transcription
-
Knutson, B. A., and Hahn, S. (2013). TFIIB-related factors in RNA polymerase I transcription. Biochim. Biophys. Acta 1829, 265-273. doi: 10.1016/j.bbagrm.2012.08.003
-
(2013)
Biochim. Biophys. Acta
, vol.1829
, pp. 265-273
-
-
Knutson, B.A.1
Hahn, S.2
-
75
-
-
77952146825
-
Nuclear phosphoinositide 3-kinase β controls double-strand break DNA repair
-
Kumar, A., Fernandez-Capetillo, O., and Carrera, A. C. (2010). Nuclear phosphoinositide 3-kinase β controls double-strand break DNA repair. Proc. Natl. Acad. Sci. U.S.A. 107, 7491-7496. doi: 10.1073/pnas.0914242107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 7491-7496
-
-
Kumar, A.1
Fernandez-Capetillo, O.2
Carrera, A.C.3
-
76
-
-
79956108913
-
Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survival
-
Kumar, A., Redondo-Muñoz, J., Perez-García, V., Cortes, I., Chagoyen, M., and Carrera, A. C. (2011). Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survival. Mol. Cell. Biol. 31, 2122-2133. doi: 10.1128/MCB.01313-10
-
(2011)
Mol. Cell. Biol
, vol.31
, pp. 2122-2133
-
-
Kumar, A.1
Redondo-Muñoz, J.2
Perez-García, V.3
Cortes, I.4
Chagoyen, M.5
Carrera, A.C.6
-
77
-
-
77952522130
-
PI(3, 4, 5)P3 regulates the interaction between Akt and B23 in the nucleus
-
Kwon, I. S., Lee, K. H., Choi, J. W., and Ahn, J. Y. (2010). PI(3, 4, 5)P3 regulates the interaction between Akt and B23 in the nucleus. BMB Rep. 43, 127-132. doi: 10.5483/BMBRep.2010.43.2.127
-
(2010)
BMB Rep
, vol.43
, pp. 127-132
-
-
Kwon, I.S.1
Lee, K.H.2
Choi, J.W.3
Ahn, J.Y.4
-
78
-
-
0035824818
-
Regulation of ribosome biogenesis within the nucleolus
-
Leary, D. J., and Huang, S. (2001). Regulation of ribosome biogenesis within the nucleolus. FEBS Lett. 509, 145-150. doi: 10.1016/S0014-5793(01)03143-X
-
(2001)
FEBS Lett
, vol.509
, pp. 145-150
-
-
Leary, D.J.1
Huang, S.2
-
79
-
-
55949109177
-
Nuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survival
-
Lee, S. B., Xuan Nguyen, T. L., Choi, J. W., Lee, K.-H., Cho, S.-W., Liu, Z., et al. (2008). Nuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survival. Proc. Natl. Acad. Sci. U.S.A. 105, 16584-16589. doi: 10.1073/pnas.0807668105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 16584-16589
-
-
Lee, S.B.1
Xuan Nguyen, T.L.2
Choi, J.W.3
Lee, K.-H.4
Cho, S.-W.5
Liu, Z.6
-
80
-
-
77954641960
-
A constitutively activated form of the p110beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice
-
Lee, S. H., Poulogiannis, G., Pyne, S., Jia, S., Zou, L., Signoretti, S., et al. (2010). A constitutively activated form of the p110beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice. Proc. Natl. Acad. Sci. U.S.A. 107, 11002-11007. doi: 10.1073/pnas.1005642107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 11002-11007
-
-
Lee, S.H.1
Poulogiannis, G.2
Pyne, S.3
Jia, S.4
Zou, L.5
Signoretti, S.6
-
81
-
-
79953173627
-
Identification of nuclear phosphatidylinositol 4, 5-bisphosphate-interacting proteins by neomycin extraction
-
Lewis, A. E., Sommer, L., Arntzen, M. O., Strahm, Y., Morrice, N. A., Divecha, N., et al. (2011). Identification of nuclear phosphatidylinositol 4, 5-bisphosphate-interacting proteins by neomycin extraction. Mol. Cell. Proteomics 10:M110.003376. doi: 10.1074/mcp.M110.003376
-
(2011)
Mol. Cell. Proteomics
, vol.10
-
-
Lewis, A.E.1
Sommer, L.2
Arntzen, M.O.3
Strahm, Y.4
Morrice, N.A.5
Divecha, N.6
-
82
-
-
84862908573
-
Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIalpha and PKCdelta signaling
-
Li, W., Laishram, R. S., Ji, Z., Barlow, C. A., Tian, B., and Anderson, R. A. (2012). Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIalpha and PKCdelta signaling. Mol. Cell 45, 25-37. doi: 10.1016/j.molcel.2011.11.017
-
(2012)
Mol. Cell
, vol.45
, pp. 25-37
-
-
Li, W.1
Laishram, R.S.2
Ji, Z.3
Barlow, C.A.4
Tian, B.5
Anderson, R.A.6
-
83
-
-
33846080045
-
Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2
-
Li, W., Petrimpol, M., Molle, K. D., Hall, M. N., Battegay, E. J., and Humar, R. (2007). Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2. Circ. Res. 100, 79-87. doi: 10.1161/01.RES.0000253094.03023.3f
-
(2007)
Circ. Res
, vol.100
, pp. 79-87
-
-
Li, W.1
Petrimpol, M.2
Molle, K.D.3
Hall, M.N.4
Battegay, E.J.5
Humar, R.6
-
84
-
-
71949128142
-
Beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt
-
Li, X., Liu, J., and Gao, T. (2009). Beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt. Mol. Cell. Biol. 29, 6192-6205. doi: 10.1128/MCB.00681-09
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 6192-6205
-
-
Li, X.1
Liu, J.2
Gao, T.3
-
85
-
-
57749116048
-
Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation
-
Li, Z., Boone, D., and Hann, S. R. (2008). Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation. Proc. Natl. Acad. Sci. U.S.A. 105, 18794-18799. doi: 10.1073/pnas.0806879105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 18794-18799
-
-
Li, Z.1
Boone, D.2
Hann, S.R.3
-
86
-
-
84876104926
-
Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription
-
Li, Z., and Hann, S. R. (2013). Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription. Oncogene 32, 1988-1994. doi: 10.1038/onc.2012.227
-
(2013)
Oncogene
, vol.32
, pp. 1988-1994
-
-
Li, Z.1
Hann, S.R.2
-
87
-
-
84921771048
-
Ribosomal proteins L5 and L11 co-operatively inactivate c-Myc via RNA-induced silencing complex
-
Liao, J.-M., Zhou, X., Gatignol, A., and Lu, H. (2014). Ribosomal proteins L5 and L11 co-operatively inactivate c-Myc via RNA-induced silencing complex. Oncogene 33, 4916-4923. doi: 10.1038/onc.2013.430
-
(2014)
Oncogene
, vol.33
, pp. 4916-4923
-
-
Liao, J.-M.1
Zhou, X.2
Gatignol, A.3
Lu, H.4
-
88
-
-
0344270855
-
Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function
-
Lim, M. A., Kikani, C. K., Wick, M. J., and Dong, L. Q. (2003). Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function. Proc. Natl. Acad. Sci. U.S.A. 100, 14006-14011. doi: 10.1073/pnas.2335486100
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 14006-14011
-
-
Lim, M.A.1
Kikani, C.K.2
Wick, M.J.3
Dong, L.Q.4
-
89
-
-
0032579216
-
Melanoma differentiation associated gene-9, mda-9, is a human gamma interferon responsive gene
-
Lin, J. J., Jiang, H., and Fisher, P. B. (1998). Melanoma differentiation associated gene-9, mda-9, is a human gamma interferon responsive gene. Gene 207, 105-110. doi: 10.1016/S0378-1119(97)00562-3
-
(1998)
Gene
, vol.207
, pp. 105-110
-
-
Lin, J.J.1
Jiang, H.2
Fisher, P.B.3
-
90
-
-
33845972919
-
Localization of agonist-sensitive PtdIns(3, 4, 5)P3 reveals a nuclear pool that is insensitive to PTEN expression
-
Lindsay, Y., McCoull, D., Davidson, L., Leslie, N. R., Fairservice, A., Gray, A., et al. (2006). Localization of agonist-sensitive PtdIns(3, 4, 5)P3 reveals a nuclear pool that is insensitive to PTEN expression. J. Cell Sci. 119, 5160-5168. doi: 10.1242/jcs.000133
-
(2006)
J. Cell Sci
, vol.119
, pp. 5160-5168
-
-
Lindsay, Y.1
McCoull, D.2
Davidson, L.3
Leslie, N.R.4
Fairservice, A.5
Gray, A.6
-
91
-
-
0029002136
-
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
-
Littlewood, T. D., Hancock, D. C., Danielian, P. S., Parker, M. G., and Evan, G. I. (1995). A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res. 23, 1686-1690. doi: 10.1093/nar/23.10.1686
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1686-1690
-
-
Littlewood, T.D.1
Hancock, D.C.2
Danielian, P.S.3
Parker, M.G.4
Evan, G.I.5
-
92
-
-
21744441932
-
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation
-
Liu, J. L., Sheng, X., Hortobagyi, Z. K., Mao, Z., Gallick, G. E., and Yung, W. K. (2005). Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation. Mol. Cell. Biol. 25, 6211-6224. doi: 10.1128/MCB.25.14.6211-6224.2005
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 6211-6224
-
-
Liu, J.L.1
Sheng, X.2
Hortobagyi, Z.K.3
Mao, Z.4
Gallick, G.E.5
Yung, W.K.6
-
93
-
-
84925256439
-
Role of AKT signaling in DNA repair and clinical response to cancer therapy
-
Liu, Q., Turner, K. M., Alfred Yung, W. K., Chen, K., and Zhang, W. (2014). Role of AKT signaling in DNA repair and clinical response to cancer therapy. Neuro Oncol. 16, 1313-1323. doi: 10.1093/neuonc/nou058
-
(2014)
Neuro Oncol
, vol.16
, pp. 1313-1323
-
-
Liu, Q.1
Turner, K.M.2
Alfred Yung, W.K.3
Chen, K.4
Zhang, W.5
-
94
-
-
84890810992
-
Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA
-
Nguyen, L. X. T., and Mitchell, B. S. (2013). Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA. Proc. Natl. Acad. Sci. U.S.A. 110, 20681-20686. doi: 10.1073/pnas.1313097110
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 20681-20686
-
-
Nguyen, L.X.T.1
Mitchell, B.S.2
-
95
-
-
84899638613
-
Translation factors and ribosomal proteins control tumor onset and progression: how?
-
Loreni, F., Mancino, M., and Biffo, S. (2014). Translation factors and ribosomal proteins control tumor onset and progression: how? Oncogene 33, 2145-2156. doi: 10.1038/onc.2013.153
-
(2014)
Oncogene
, vol.33
, pp. 2145-2156
-
-
Loreni, F.1
Mancino, M.2
Biffo, S.3
-
96
-
-
0025580878
-
The numerous modified nucleotides in eukaryotic ribosomal RNA
-
Maden, B. E. (1990). The numerous modified nucleotides in eukaryotic ribosomal RNA. Prog. Nucleic Acid Res. Mol. Biol. 39, 241-303. doi: 10.1016/S0079-6603(08)60629-7
-
(1990)
Prog. Nucleic Acid Res. Mol. Biol
, vol.39
, pp. 241-303
-
-
Maden, B.E.1
-
97
-
-
0034723152
-
DNA polymerase switching: I Replication factor C displaces DNA polymerase alpha prior to PCNA loading
-
Maga, G., Stucki, M., Spadari, S., and Hübscher, U. (2000). DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading. J. Mol. Biol. 295, 791-801. doi: 10.1006/jmbi.1999.3394
-
(2000)
J. Mol. Biol
, vol.295
, pp. 791-801
-
-
Maga, G.1
Stucki, M.2
Spadari, S.3
Hübscher, U.4
-
98
-
-
84862103119
-
PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics
-
Mahajan, K., and Mahajan, N. P. (2012). PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics. J. Cell. Physiol. 227, 3178-3184. doi: 10.1002/jcp.24065
-
(2012)
J. Cell. Physiol
, vol.227
, pp. 3178-3184
-
-
Mahajan, K.1
Mahajan, N.P.2
-
99
-
-
0018049518
-
Chromatin lipids and their possible role in gene expression A study in normal and neoplastic cells
-
Manzoli, F. A., Capitani, S., Maraldi, N. M., Cocco, L., and Barnabei, O. (1978). Chromatin lipids and their possible role in gene expression. A study in normal and neoplastic cells. Adv. Enzyme Regul. 17, 175-194. doi: 10.1016/0065-2571(79)90013-X
-
(1978)
Adv. Enzyme Regul
, vol.17
, pp. 175-194
-
-
Manzoli, F.A.1
Capitani, S.2
Maraldi, N.M.3
Cocco, L.4
Barnabei, O.5
-
100
-
-
0020015278
-
Role of chromatin phospholipids on template availability and ultrastructure of isolated nuclei
-
Manzoli, F. A., Capitani, S., Mazzotti, G., Barnabei, O., and Maraldi, N. M. (1982). Role of chromatin phospholipids on template availability and ultrastructure of isolated nuclei. Adv. Enzyme Regul. 20, 247-262. doi: 10.1016/0065-2571(82)90019-X
-
(1982)
Adv. Enzyme Regul
, vol.20
, pp. 247-262
-
-
Manzoli, F.A.1
Capitani, S.2
Mazzotti, G.3
Barnabei, O.4
Maraldi, N.M.5
-
101
-
-
42149140646
-
Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase
-
Marqués, M., Kumar, A., Cortés, I., Gonzalez-García, A., Hernández, C., Moreno-Ortiz, M. C., et al. (2008). Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase. Mol. Cell. Biol. 28, 2803-2814. doi: 10.1128/MCB.01786-07
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 2803-2814
-
-
Marqués, M.1
Kumar, A.2
Cortés, I.3
Gonzalez-García, A.4
Hernández, C.5
Moreno-Ortiz, M.C.6
-
102
-
-
66149112970
-
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication
-
Marqués, M., Kumar, A., Poveda, A. M., Zuluaga, S., Hernández, C., Jackson, S., et al. (2009). Specific function of phosphoinositide 3-kinase beta in the control of DNA replication. Proc. Natl. Acad. Sci. U.S.A. 106, 7525-7530. doi: 10.1073/pnas.0812000106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 7525-7530
-
-
Marqués, M.1
Kumar, A.2
Poveda, A.M.3
Zuluaga, S.4
Hernández, C.5
Jackson, S.6
-
103
-
-
84867283425
-
The emerging multiple roles of nuclear Akt
-
Martelli, A. M., Tabellini, G., Bressanin, D., Ognibene, A., Goto, K., Cocco, L., et al. (2012). The emerging multiple roles of nuclear Akt. Biochim. Biophys. Acta 1823, 2168-2178. doi: 10.1016/j.bbamcr.2012.08.017
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 2168-2178
-
-
Martelli, A.M.1
Tabellini, G.2
Bressanin, D.3
Ognibene, A.4
Goto, K.5
Cocco, L.6
-
104
-
-
33750044901
-
Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases
-
Mayer, C., and Grummt, I. (2006). Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases. Oncogene 25, 6384-6391. doi: 10.1038/sj.onc.1209883
-
(2006)
Oncogene
, vol.25
, pp. 6384-6391
-
-
Mayer, C.1
Grummt, I.2
-
105
-
-
84871491627
-
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance
-
McCubrey, J. A., Steelman, L. S., Chappell, W. H., Abrams, S. L., Franklin, R. A., Montalto, G., et al. (2012). Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance. Oncotarget 3, 1068-1111
-
(2012)
Oncotarget
, vol.3
, pp. 1068-1111
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
Abrams, S.L.4
Franklin, R.A.5
Montalto, G.6
-
106
-
-
0032493894
-
The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins
-
McMahon, S. B., Van Buskirk, H. A., Dugan, K. A., Copeland, T. D., and Cole, M. D. (1998). The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94, 363-374. doi: 10.1016/S0092-8674(00)81479-8
-
(1998)
Cell
, vol.94
, pp. 363-374
-
-
McMahon, S.B.1
Van Buskirk, H.A.2
Dugan, K.A.3
Copeland, T.D.4
Cole, M.D.5
-
107
-
-
0030727172
-
Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta
-
Meier, R., Alessi, D. R., Cron, P., Andjelkovic, M., and Hemmings, B. A. (1997). Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta. J. Biol. Chem. 272, 30491-30497. doi: 10.1074/jbc.272.48.30491
-
(1997)
J. Biol. Chem
, vol.272
, pp. 30491-30497
-
-
Meier, R.1
Alessi, D.R.2
Cron, P.3
Andjelkovic, M.4
Hemmings, B.A.5
-
108
-
-
39749101733
-
A PtdIns4, 5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
-
Mellman, D. L., Gonzales, M. L., Song, C., Barlow, C. A., Wang, P., Kendziorski, C., et al. (2008). A PtdIns4, 5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs. Nature 451, 1013-1017. doi: 10.1038/nature06666
-
(2008)
Nature
, vol.451
, pp. 1013-1017
-
-
Mellman, D.L.1
Gonzales, M.L.2
Song, C.3
Barlow, C.A.4
Wang, P.5
Kendziorski, C.6
-
109
-
-
79958026380
-
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
-
Mendoza, M. C., Er, E. E., and Blenis, J. (2011). The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation. Trends Biochem. Sci. 36, 320-328. doi: 10.1016/j.tibs.2011.03.006
-
(2011)
Trends Biochem. Sci
, vol.36
, pp. 320-328
-
-
Mendoza, M.C.1
Er, E.E.2
Blenis, J.3
-
110
-
-
0035869039
-
hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters
-
Miller, G., Panov, K. I., Friedrich, J. K., Trinkle-Mulcahy, L., Lamond, A. I., and Zomerdijk, J. C. (2001). hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters. EMBO J. 20, 1373-1382. doi: 10.1093/emboj/20.6.1373
-
(2001)
EMBO J
, vol.20
, pp. 1373-1382
-
-
Miller, G.1
Panov, K.I.2
Friedrich, J.K.3
Trinkle-Mulcahy, L.4
Lamond, A.I.5
Zomerdijk, J.C.6
-
111
-
-
77956236967
-
Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatases
-
Mistafa, O., Ghalali, A., Kadekar, S., Högberg, J., and Stenius, U. (2010). Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatases. J. Biol. Chem. 285, 27900-27910. doi: 10.1074/jbc.M110.117093
-
(2010)
J. Biol. Chem
, vol.285
, pp. 27900-27910
-
-
Mistafa, O.1
Ghalali, A.2
Kadekar, S.3
Högberg, J.4
Stenius, U.5
-
112
-
-
0031834613
-
The cellular organization of gene expression
-
Misteli, T., and Spector, D. L. (1998). The cellular organization of gene expression. Curr. Opin. Cell Biol. 10, 323-331. doi: 10.1016/S0955-0674(98)80007-0
-
(1998)
Curr. Opin. Cell Biol
, vol.10
, pp. 323-331
-
-
Misteli, T.1
Spector, D.L.2
-
113
-
-
84872738779
-
Phosphoinositide 3-kinase gamma inhibits cardiac GSK-3 independently of Akt
-
Mohan, M. L., Jha, B. K., Gupta, M. K., Vasudevan, N. T., Martelli, E. E., Mosinski, J. D., et al. (2013). Phosphoinositide 3-kinase gamma inhibits cardiac GSK-3 independently of Akt. Sci. Signal. 6:ra4. doi: 10.1126/scisignal.2003308
-
(2013)
Sci. Signal
, vol.6
, pp. 4
-
-
Mohan, M.L.1
Jha, B.K.2
Gupta, M.K.3
Vasudevan, N.T.4
Martelli, E.E.5
Mosinski, J.D.6
-
114
-
-
23044468282
-
Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions
-
Mortier, E., Wuytens, G., Leenaerts, I., Hannes, F., Heung, M. Y., Degeest, G., et al. (2005). Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions. EMBO J. 24, 2556-2565. doi: 10.1038/sj.emboj.7600722
-
(2005)
EMBO J
, vol.24
, pp. 2556-2565
-
-
Mortier, E.1
Wuytens, G.2
Leenaerts, I.3
Hannes, F.4
Heung, M.Y.5
Degeest, G.6
-
115
-
-
77649175453
-
Genomic instability-an evolving hallmark of cancer
-
Negrini, S., Gorgoulis, V. G., and Halazonetis, T. D. (2010). Genomic instability-an evolving hallmark of cancer. Nat. Rev. Mol. Cell Biol. 11, 220-228. doi: 10.1038/nrm2858
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 220-228
-
-
Negrini, S.1
Gorgoulis, V.G.2
Halazonetis, T.D.3
-
116
-
-
0345193700
-
Nuclear translocation of phosphatidylinositol 3-kinase in rat pheochromocytoma PC 12 cells after treatment with nerve growth factor
-
Neri, L. M., Milani, D., Bertolaso, L., Stroscio, M., Bertagnolo, V., and Capitani, S. (1994). Nuclear translocation of phosphatidylinositol 3-kinase in rat pheochromocytoma PC 12 cells after treatment with nerve growth factor. Cell. Mol. Biol. 40, 619-626
-
(1994)
Cell. Mol. Biol
, vol.40
, pp. 619-626
-
-
Neri, L.M.1
Milani, D.2
Bertolaso, L.3
Stroscio, M.4
Bertagnolo, V.5
Capitani, S.6
-
117
-
-
84867010006
-
c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Nie, Z., Hu, G., Wei, G., Cui, K., Yamane, A., Resch, W., et al. (2012). c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 151, 68-79. doi: 10.1016/j.cell.2012.08.033
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
Cui, K.4
Yamane, A.5
Resch, W.6
-
118
-
-
0034677903
-
A role for nuclear inositol 1, 4, 5-trisphosphate kinase in transcriptional control
-
Odom, A. R., Stahlberg, A., Wente, S. R., and York, J. D. (2000). A role for nuclear inositol 1, 4, 5-trisphosphate kinase in transcriptional control. Science 287, 2026-2029. doi: 10.1126/science.287.5460.2026
-
(2000)
Science
, vol.287
, pp. 2026-2029
-
-
Odom, A.R.1
Stahlberg, A.2
Wente, S.R.3
York, J.D.4
-
119
-
-
47249128932
-
Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY
-
Okada, M., Jang, S.-W., and Ye, K. (2008). Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY. Proc. Natl. Acad. Sci. U.S.A. 105, 8649-8654. doi: 10.1073/pnas.0802533105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 8649-8654
-
-
Okada, M.1
Jang, S.-W.2
Ye, K.3
-
120
-
-
4344714889
-
PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and-independent effects
-
Patrucco, E., Notte, A., Barberis, L., Selvetella, G., Maffei, A., Brancaccio, M., et al. (2004). PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and-independent effects. Cell 118, 375-387. doi: 10.1016/j.cell.2004.07.017
-
(2004)
Cell
, vol.118
, pp. 375-387
-
-
Patrucco, E.1
Notte, A.2
Barberis, L.3
Selvetella, G.4
Maffei, A.5
Brancaccio, M.6
-
121
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., and Bonner, W. M. (2000). A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10, 886-895. doi: 10.1016/S0960-9822(00)00610-2
-
(2000)
Curr. Biol
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
122
-
-
69249228672
-
FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt
-
Pei, H., Li, L., Fridley, B. L., Jenkins, G. D., Kalari, K. R., Lingle, W., et al. (2009). FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. Cancer Cell 16, 259-266. doi: 10.1016/j.ccr.2009.07.016
-
(2009)
Cancer Cell
, vol.16
, pp. 259-266
-
-
Pei, H.1
Li, L.2
Fridley, B.L.3
Jenkins, G.D.4
Kalari, K.R.5
Lingle, W.6
-
123
-
-
20844440353
-
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
-
Poortinga, G., Hannan, K. M., Snelling, H., Walkley, C. R., Jenkins, A., Sharkey, K., et al. (2004). MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation. EMBO J. 23, 3325-3335. doi: 10.1038/sj.emboj.7600335
-
(2004)
EMBO J
, vol.23
, pp. 3325-3335
-
-
Poortinga, G.1
Hannan, K.M.2
Snelling, H.3
Walkley, C.R.4
Jenkins, A.5
Sharkey, K.6
-
124
-
-
60749136137
-
SHIP2 phosphoinositol phosphatase positively regulates EGFR-Akt pathway, CXCR4 expression, and cell migration in MDA-MB-231 breast cancer cells
-
Prasad, N. K. (2009). SHIP2 phosphoinositol phosphatase positively regulates EGFR-Akt pathway, CXCR4 expression, and cell migration in MDA-MB-231 breast cancer cells. Int. J. Oncol. 34, 97-105. doi: 10.3892/ijo_00000133
-
(2009)
Int. J. Oncol
, vol.34
, pp. 97-105
-
-
Prasad, N.K.1
-
125
-
-
38849148269
-
Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover
-
Prasad, N. K., Tandon, M., Badve, S., Snyder, P. W., and Nakshatri, H. (2008). Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover. Carcinogenesis 29, 25-34. doi: 10.1093/carcin/bgm213
-
(2008)
Carcinogenesis
, vol.29
, pp. 25-34
-
-
Prasad, N.K.1
Tandon, M.2
Badve, S.3
Snyder, P.W.4
Nakshatri, H.5
-
126
-
-
84876533724
-
Regulation of mRNA export by the PI3 kinase/AKT signal transduction pathway
-
Quaresma, A. J., Sievert, R., and Nickerson, J. A. (2013). Regulation of mRNA export by the PI3 kinase/AKT signal transduction pathway. Mol. Biol. Cell 24, 1208-1221. doi: 10.1091/mbc.E12-06-0450
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 1208-1221
-
-
Quaresma, A.J.1
Sievert, R.2
Nickerson, J.A.3
-
127
-
-
84875427448
-
Phosphoinositide 3-kinase beta controls replication factor C assembly and function
-
Redondo-Muñoz, J., Rodríguez, M. J., Silió, V., Pérez-García, V., Valpuesta, J. M., and Carrera, A. C. (2013). Phosphoinositide 3-kinase beta controls replication factor C assembly and function. Nucleic Acids Res. 41, 855-868. doi: 10.1093/nar/gks1095
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 855-868
-
-
Redondo-Muñoz, J.1
Rodríguez, M.J.2
Silió, V.3
Pérez-García, V.4
Valpuesta, J.M.5
Carrera, A.C.6
-
128
-
-
24644503488
-
Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity
-
Resnick, A. C., Snowman, A. M., Kang, B. N., Hurt, K. J., Snyder, S. H., and Saiardi, A. (2005). Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity. Proc. Natl. Acad. Sci. U.S.A. 102, 12783-12788. doi: 10.1073/pnas.0506184102
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 12783-12788
-
-
Resnick, A.C.1
Snowman, A.M.2
Kang, B.N.3
Hurt, K.J.4
Snyder, S.H.5
Saiardi, A.6
-
129
-
-
84883556505
-
Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer
-
Saini, K. S., Loi, S., de Azambuja, E., Metzger-Filho, O., Saini, M. L., Ignatiadis, M., et al. (2013). Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer. Cancer Treat. Rev. 39, 935-946. doi: 10.1016/j.ctrv.2013.03.009
-
(2013)
Cancer Treat. Rev
, vol.39
, pp. 935-946
-
-
Saini, K.S.1
Loi, S.2
de Azambuja, E.3
Metzger-Filho, O.4
Saini, M.L.5
Ignatiadis, M.6
-
130
-
-
77749292082
-
The Akt isoforms are present at distinct subcellular locations
-
Santi, S. A., and Lee, H. (2010). The Akt isoforms are present at distinct subcellular locations. Am. J. Physiol. Cell Physiol. 298, C580-C591. doi: 10.1152/ajpcell.00375.2009
-
(2010)
Am. J. Physiol. Cell Physiol
, vol.298
, pp. C580-C591
-
-
Santi, S.A.1
Lee, H.2
-
131
-
-
0032189707
-
Preferential cleavage in pre-ribosomal RNA byprotein B23 endoribonuclease
-
Savkur, R. S., and Olson, M. O. (1998). Preferential cleavage in pre-ribosomal RNA byprotein B23 endoribonuclease. Nucleic Acids Res. 26, 4508-4515. doi: 10.1093/nar/26.19.4508
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 4508-4515
-
-
Savkur, R.S.1
Olson, M.O.2
-
132
-
-
0037088681
-
Phosphatidylinositol (3, 4, 5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3, 4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockout mice
-
Scheid, M. P., Huber, M., Damen, J. E., Hughes, M., Kang, V., Neilsen, P., et al. (2002). Phosphatidylinositol (3, 4, 5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3, 4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockout mice. J. Biol. Chem. 277, 9027-9035. doi: 10.1074/jbc.M106755200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 9027-9035
-
-
Scheid, M.P.1
Huber, M.2
Damen, J.E.3
Hughes, M.4
Kang, V.5
Neilsen, P.6
-
133
-
-
70249119300
-
Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting
-
Schill, N. J., and Anderson, R. A. (2009). Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting. Biochem. J. 422, 473-482. doi: 10.1042/BJ20090638
-
(2009)
Biochem. J
, vol.422
, pp. 473-482
-
-
Schill, N.J.1
Anderson, R.A.2
-
134
-
-
0344442399
-
A role for c-Myc in the regulation of ribosomal RNA processing
-
Schlosser, I., Hölzel, M., Mürnseer, M., Burtscher, H., Weidle, U. H., and Eick, D. (2003). A role for c-Myc in the regulation of ribosomal RNA processing. Nucleic Acids Res. 31, 6148-6156. doi: 10.1093/nar/gkg794
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6148-6156
-
-
Schlosser, I.1
Hölzel, M.2
Mürnseer, M.3
Burtscher, H.4
Weidle, U.H.5
Eick, D.6
-
135
-
-
84929141919
-
Feedback suppression of PI3Kalpha signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kbeta
-
Schwartz, S., Wongvipat, J., Trigwell, C. B., Hancox, U., Carver, B. S., Rodrik-Outmezguine, V., et al. (2015). Feedback suppression of PI3Kalpha signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kbeta. Cancer Cell 27, 109-122. doi: 10.1016/j.ccell.2014.11.008
-
(2015)
Cancer Cell
, vol.27
, pp. 109-122
-
-
Schwartz, S.1
Wongvipat, J.2
Trigwell, C.B.3
Hancox, U.4
Carver, B.S.5
Rodrik-Outmezguine, V.6
-
136
-
-
0942290439
-
How versatile are inositol phosphate kinases?
-
Shears, S. B. (2004). How versatile are inositol phosphate kinases? Biochem. J. 377, 265-280. doi: 10.1042/BJ20031428
-
(2004)
Biochem. J
, vol.377
, pp. 265-280
-
-
Shears, S.B.1
-
137
-
-
33845999615
-
Essential role for nuclear PTEN in maintaining chromosomal integrity
-
Shen, W. H., Balajee, A. S., Wang, J., Wu, H., Eng, C., Pandolfi, P. P., et al. (2007). Essential role for nuclear PTEN in maintaining chromosomal integrity. Cell 128, 157-170. doi: 10.1016/j.cell.2006.11.042
-
(2007)
Cell
, vol.128
, pp. 157-170
-
-
Shen, W.H.1
Balajee, A.S.2
Wang, J.3
Wu, H.4
Eng, C.5
Pandolfi, P.P.6
-
138
-
-
84901321338
-
Myc-induced anchorage of the rDNA IGS region to nucleolar matrix modulates growth-stimulated changes in higher-order rDNA architecture
-
Shiue, C.-N., Nematollahi-Mahani, A., and Wright, A. P. H. (2014). Myc-induced anchorage of the rDNA IGS region to nucleolar matrix modulates growth-stimulated changes in higher-order rDNA architecture. Nucleic Acids Res. 42, 5505-5517. doi: 10.1093/nar/gku183
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 5505-5517
-
-
Shiue, C.-N.1
Nematollahi-Mahani, A.2
Wright, A.P.H.3
-
139
-
-
77952036652
-
Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells
-
Shor, B., Wu, J., Shakey, Q., Toral-Barza, L., Shi, C., Follettie, M., et al. (2010). Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells. J. Biol. Chem. 285, 15380-15392. doi: 10.1074/jbc.M109.071639
-
(2010)
J. Biol. Chem
, vol.285
, pp. 15380-15392
-
-
Shor, B.1
Wu, J.2
Shakey, Q.3
Toral-Barza, L.4
Shi, C.5
Follettie, M.6
-
140
-
-
84870487409
-
Phosphoinositide 3-kinase beta regulates chromosome segregation in mitosis
-
Silio, V., Redondo-Munoz, J., and Carrera, A. C. (2012). Phosphoinositide 3-kinase beta regulates chromosome segregation in mitosis. Mol. Biol. Cell 23, 4526-4542. doi: 10.1091/mbc.E12-05-0371
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 4526-4542
-
-
Silio, V.1
Redondo-Munoz, J.2
Carrera, A.C.3
-
141
-
-
33748031715
-
Activation of phosphoinositide 3-kinase C2 beta in the nuclear matrix during compensatory liver growth
-
Sindic, A., Crljen, V., Matkovic, K., Lukinovic-Skudar, V., Visnjic, D., and Banfic, H. (2006). Activation of phosphoinositide 3-kinase C2 beta in the nuclear matrix during compensatory liver growth. Adv. Enzyme Regul. 46, 280-287. doi: 10.1016/j.advenzreg.2006.01.008
-
(2006)
Adv. Enzyme Regul
, vol.46
, pp. 280-287
-
-
Sindic, A.1
Crljen, V.2
Matkovic, K.3
Lukinovic-Skudar, V.4
Visnjic, D.5
Banfic, H.6
-
142
-
-
78651482046
-
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
-
Song, M. S., Carracedo, A., Salmena, L., Song, S. J., Egia, A., Malumbres, M., et al. (2011). Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner. Cell 144, 187-199. doi: 10.1016/j.cell.2010.12.020
-
(2011)
Cell
, vol.144
, pp. 187-199
-
-
Song, M.S.1
Carracedo, A.2
Salmena, L.3
Song, S.J.4
Egia, A.5
Malumbres, M.6
-
143
-
-
84860217431
-
The functions and regulation of the PTEN tumour suppressor
-
Song, M. S., Salmena, L., and Pandolfi, P. P. (2012). The functions and regulation of the PTEN tumour suppressor. Nat. Rev. Mol. Cell Biol. 13, 283-296. doi: 10.1038/nrm3330
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 283-296
-
-
Song, M.S.1
Salmena, L.2
Pandolfi, P.P.3
-
144
-
-
33750571668
-
Mutational analysis of AKT1, AKT2 and AKT3 genes in common human carcinomas
-
Soung, Y. H., Lee, J. W., Nam, S. W., Lee, J. Y., Yoo, N. J., and Lee, S. H. (2006). Mutational analysis of AKT1, AKT2 and AKT3 genes in common human carcinomas. Oncology 70, 285-289. doi: 10.1159/000096289
-
(2006)
Oncology
, vol.70
, pp. 285-289
-
-
Soung, Y.H.1
Lee, J.W.2
Nam, S.W.3
Lee, J.Y.4
Yoo, N.J.5
Lee, S.H.6
-
146
-
-
84892397073
-
Developments in Burkitt's lymphoma: novel cooperations in oncogenic MYC signaling
-
Spender, L. C., and Inman, G. J. (2014). Developments in Burkitt's lymphoma: novel cooperations in oncogenic MYC signaling. Cancer Manag. Res. 6, 27-38. doi: 10.2147/CMAR.S37745
-
(2014)
Cancer Manag. Res
, vol.6
, pp. 27-38
-
-
Spender, L.C.1
Inman, G.J.2
-
147
-
-
0033548232
-
Evidence that a phosphatidylinositol 3, 4, 5-trisphosphate-binding protein can function in nucleus
-
Tanaka, K., Horiguchi, K., Yoshida, T., Takeda, M., Fujisawa, H., Takeuchi, K., et al. (1999). Evidence that a phosphatidylinositol 3, 4, 5-trisphosphate-binding protein can function in nucleus. J. Biol. Chem. 274, 3919-3922. doi: 10.1074/jbc.274.7.3919
-
(1999)
J. Biol. Chem
, vol.274
, pp. 3919-3922
-
-
Tanaka, K.1
Horiguchi, K.2
Yoshida, T.3
Takeda, M.4
Fujisawa, H.5
Takeuchi, K.6
-
148
-
-
84928927872
-
Mammalian MYC proteins and cancer
-
Tansey, W. P. (2014). Mammalian MYC proteins and cancer. New J. Sci. 2014:757534. doi: 10.1155/2014/757534
-
(2014)
New J. Sci
, vol.2014
-
-
Tansey, W.P.1
-
149
-
-
84899739046
-
Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions
-
Tapias, A., Zhou, Z. W., Shi, Y., Chong, Z., Wang, P., Groth, M., et al. (2014). Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions. Cell Stem Cell 14, 632-643. doi: 10.1016/j.stem.2014.04.001
-
(2014)
Cell Stem Cell
, vol.14
, pp. 632-643
-
-
Tapias, A.1
Zhou, Z.W.2
Shi, Y.3
Chong, Z.4
Wang, P.5
Groth, M.6
-
150
-
-
0001292985
-
Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells
-
Taub, R., Kirsch, I., Morton, C., Lenoir, G., Swan, D., Tronick, S., et al. (1982). Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc. Natl. Acad. Sci. U.S.A. 79, 7837-7841. doi: 10.1073/pnas.79.24.7837
-
(1982)
Proc. Natl. Acad. Sci. U.S.A
, vol.79
, pp. 7837-7841
-
-
Taub, R.1
Kirsch, I.2
Morton, C.3
Lenoir, G.4
Swan, D.5
Tronick, S.6
-
151
-
-
79959450256
-
Proteolytic control of the oncoprotein transcription factor Myc
-
Thomas, L. R., and Tansey, W. P. (2011). Proteolytic control of the oncoprotein transcription factor Myc. Adv. Cancer Res. 110, 77-106. doi: 10.1016/B978-0-12-386469-7.00004-9
-
(2011)
Adv. Cancer Res
, vol.110
, pp. 77-106
-
-
Thomas, L.R.1
Tansey, W.P.2
-
152
-
-
33845977965
-
Ubiquitination regulates PTEN nuclear import and tumor suppression
-
Trotman, L. C., Wang, X., Alimonti, A., Chen, Z., Teruya-Feldstein, J., Yang, H., et al. (2007). Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell 128, 141-156. doi: 10.1016/j.cell.2006.11.040
-
(2007)
Cell
, vol.128
, pp. 141-156
-
-
Trotman, L.C.1
Wang, X.2
Alimonti, A.3
Chen, Z.4
Teruya-Feldstein, J.5
Yang, H.6
-
153
-
-
0038738334
-
Pre-ribosomes on the road from the nucleolus to the cytoplasm
-
Tschochner, H., and Hurt, E. (2003). Pre-ribosomes on the road from the nucleolus to the cytoplasm. Trends Cell Biol. 13, 255-263. doi: 10.1016/S0962-8924(03)00054-0
-
(2003)
Trends Cell Biol
, vol.13
, pp. 255-263
-
-
Tschochner, H.1
Hurt, E.2
-
154
-
-
0032937828
-
Cycling, stressed-out and nervous: cellular functions of c-Abl
-
Van Etten, R. A. (1999). Cycling, stressed-out and nervous: cellular functions of c-Abl. Trends Cell Biol. 9, 179-186. doi: 10.1016/S0962-8924(99)01549-4
-
(1999)
Trends Cell Biol
, vol.9
, pp. 179-186
-
-
Van Etten, R.A.1
-
155
-
-
77951621262
-
The emerging mechanisms of isoform-specific PI3K signalling
-
Vanhaesebroeck, B., Guillermet-Guibert, J., Graupera, M., and Bilanges, B. (2010). The emerging mechanisms of isoform-specific PI3K signalling. Nat. Rev. Mol. Cell Biol. 11, 329-341. doi: 10.1038/nrm2882
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 329-341
-
-
Vanhaesebroeck, B.1
Guillermet-Guibert, J.2
Graupera, M.3
Bilanges, B.4
-
156
-
-
0025967280
-
Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants
-
Varticovski, L., Daley, G. Q., Jackson, P., Baltimore, D., and Cantley, L. C. (1991). Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants. Mol. Cell. Biol. 11, 1107-1113
-
(1991)
Mol. Cell. Biol
, vol.11
, pp. 1107-1113
-
-
Varticovski, L.1
Daley, G.Q.2
Jackson, P.3
Baltimore, D.4
Cantley, L.C.5
-
157
-
-
0035122485
-
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase
-
Vigneri, P., and Wang, J. Y. (2001). Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nat. Med. 7, 228-234. doi: 10.1038/84683
-
(2001)
Nat. Med
, vol.7
, pp. 228-234
-
-
Vigneri, P.1
Wang, J.Y.2
-
158
-
-
0037048652
-
The activation of nuclear phosphoinositide 3-kinase C2beta in all-trans-retinoic acid-differentiated HL-60 cells
-
Visnjic, D., Crljen, V., Curic, J., Batinic, D., Volinia, S., and Banfic, H. (2002). The activation of nuclear phosphoinositide 3-kinase C2beta in all-trans-retinoic acid-differentiated HL-60 cells. FEBS Lett. 529, 268-274. doi: 10.1016/S0014-5793(02)03357-4
-
(2002)
FEBS Lett
, vol.529
, pp. 268-274
-
-
Visnjic, D.1
Crljen, V.2
Curic, J.3
Batinic, D.4
Volinia, S.5
Banfic, H.6
-
159
-
-
12244275663
-
Nuclear phosphoinositide 3-kinase C2beta activation during G2/M phase of the cell cycle in HL-60 cells
-
Visnjic, D., Curic, J., Crljen, V., Batinic, D., Volinia, S., and Banfic, H. (2003). Nuclear phosphoinositide 3-kinase C2beta activation during G2/M phase of the cell cycle in HL-60 cells. Biochim. Biophys. Acta 1631, 61-71. doi: 10.1016/S1388-1981(02)00356-6
-
(2003)
Biochim. Biophys. Acta
, vol.1631
, pp. 61-71
-
-
Visnjic, D.1
Curic, J.2
Crljen, V.3
Batinic, D.4
Volinia, S.5
Banfic, H.6
-
160
-
-
80051670473
-
FKBP51 regulation of AKT/protein kinase B phosphorylation
-
Wang, L. (2011). FKBP51 regulation of AKT/protein kinase B phosphorylation. Curr. Opin. Pharmacol. 11, 360-364. doi: 10.1016/j.coph.2011.03.008
-
(2011)
Curr. Opin. Pharmacol
, vol.11
, pp. 360-364
-
-
Wang, L.1
-
161
-
-
0028176021
-
Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation
-
Wang, Q. M., Fiol, C. J., DePaoli-Roach, A. A., and Roach, P. J. (1994). Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation. J. Biol. Chem. 269, 14566-14574
-
(1994)
J. Biol. Chem
, vol.269
, pp. 14566-14574
-
-
Wang, Q.M.1
Fiol, C.J.2
DePaoli-Roach, A.A.3
Roach, P.J.4
-
162
-
-
0033229970
-
The economics of ribosome biosynthesis in yeast
-
Warner, J. R. (1999). The economics of ribosome biosynthesis in yeast. Trends Biochem. Sci. 24, 437-440. doi: 10.1016/S0968-0004(99)01460-7
-
(1999)
Trends Biochem. Sci
, vol.24
, pp. 437-440
-
-
Warner, J.R.1
-
163
-
-
84884557256
-
Human inositol polyphosphate multikinase regulates transcript-selective nuclear mRNA export to preserve genome integrity
-
Wickramasinghe, V. O., Savill, J. M., Chavali, S., Jonsdottir, A. B., Rajendra, E., Grüner, T., et al. (2013). Human inositol polyphosphate multikinase regulates transcript-selective nuclear mRNA export to preserve genome integrity. Mol. Cell 51, 737-750. doi: 10.1016/j.molcel.2013.08.031
-
(2013)
Mol. Cell
, vol.51
, pp. 737-750
-
-
Wickramasinghe, V.O.1
Savill, J.M.2
Chavali, S.3
Jonsdottir, A.B.4
Rajendra, E.5
Grüner, T.6
-
164
-
-
84855334413
-
MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells
-
Yamamura, S., Saini, S., Majid, S., Hirata, H., Ueno, K., Deng, G., et al. (2012). MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. PLoS ONE 7:e29722. doi: 10.1371/journal.pone.0029722
-
(2012)
PLoS ONE
, vol.7
-
-
Yamamura, S.1
Saini, S.2
Majid, S.3
Hirata, H.4
Ueno, K.5
Deng, G.6
-
165
-
-
0033637979
-
Pik A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N
-
Ye, K., Hurt, K. J., Wu, F. Y., Fang, M., Luo, H. R., Hong, J. J., et al. (2000). Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N. Cell 103, 919-930. doi: 10.1016/S0092-8674(00)00195-1
-
(2000)
Cell
, vol.103
, pp. 919-930
-
-
Ye, K.1
Hurt, K.J.2
Wu, F.Y.3
Fang, M.4
Luo, H.R.5
Hong, J.J.6
-
166
-
-
84855885805
-
Silencing p110β prevents rapid depletion of nuclear pAkt
-
Ye, Z.-W., Ghalali, A., Högberg, J., and Stenius, U. (2011). Silencing p110β prevents rapid depletion of nuclear pAkt. Biochem. Biophys. Res. Commun. 415, 613-618. doi: 10.1016/j.bbrc.2011.10.120
-
(2011)
Biochem. Biophys. Res. Commun
, vol.415
, pp. 613-618
-
-
Ye, Z.-W.1
Ghalali, A.2
Högberg, J.3
Stenius, U.4
-
167
-
-
0030810618
-
Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response
-
Yuan, Z. M., Utsugisawa, T., Huang, Y., Ishiko, T., Nakada, S., Kharbanda, S., et al. (1997). Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response. J. Biol. Chem. 272, 23485-23488. doi: 10.1074/jbc.272.38.23485
-
(1997)
J. Biol. Chem
, vol.272
, pp. 23485-23488
-
-
Yuan, Z.M.1
Utsugisawa, T.2
Huang, Y.3
Ishiko, T.4
Nakada, S.5
Kharbanda, S.6
-
168
-
-
84872619062
-
Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress
-
Zhou, X., Hao, Q., Liao, J., Zhang, Q., and Lu, H. (2013). Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress. Oncogene 32, 388-396. doi: 10.1038/onc.2012.63
-
(2013)
Oncogene
, vol.32
, pp. 388-396
-
-
Zhou, X.1
Hao, Q.2
Liao, J.3
Zhang, Q.4
Lu, H.5
-
169
-
-
76149141839
-
Protein phosphatase 2A PR130/B'alpha1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling
-
Zwaenepoel, K., Goris, J., Erneux, C., Parker, P. J., and Janssens, V. (2010). Protein phosphatase 2A PR130/B'alpha1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling. FASEB J. 24, 538-547. doi: 10.1096/fj.09-140228
-
(2010)
FASEB J
, vol.24
, pp. 538-547
-
-
Zwaenepoel, K.1
Goris, J.2
Erneux, C.3
Parker, P.J.4
Janssens, V.5
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